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The map label for this gene is bsaA [H]

Identifier: 38234492

GI number: 38234492

Start: 1978463

End: 1978933

Strand: Reverse

Name: bsaA [H]

Synonym: DIP1925

Alternate gene names: 38234492

Gene position: 1978933-1978463 (Counterclockwise)

Preceding gene: 38234493

Following gene: 38234489

Centisome position: 79.52

GC content: 50.32

Gene sequence:

>471_bases
ATGAGTATTTTAGATACCGAGGTCACGCTGATCAACGGCGAGAAAGCCTCAATGGATCAGTGGGCTGGTCATTGCCTGTT
GATTGTGAATACGGCATCAGAGTGCGGCTATACCCCGCAGCTGGAGACGCTGGAAGAGCTTTATGAGGATTATGCGATGC
GTGGTTTCTTCGTAATCGGTGTTCCGTGTAACCAGTTCGGGGAGGAAGAACCTGGCAAGGATGCTCAGGTGGCGCGTCGA
TACGAAGAAAAGTTTGGGGTGCGCTTCCCGCTGTTGGCTAAGTCGGACGTCAATGGCCCCAACACTATTGAGCTGTATAA
GAAGCTCAAGGGTGATGGTCCAGATATTGAGTGGAACTTTGAAAAGTTTATCGTAGCGCCCAGCGGTGAGGTGGTAGGCC
GCTTTGCGCCCTCGCTTGATCCTGACGATATGAAGATCATTAACGTCTTAGAAGAGTATCTTCCTATCTAA

Upstream 100 bases:

>100_bases
GCTGGTCACGGCGGTGTTTCAGGCCGTTATGAAAAGTGGAAGCAAACCGCGTTTGAATACGCTTGGCTGTGCCATCAAGC
AACCGGAAAGGAATCCTAGG

Downstream 100 bases:

>100_bases
ATAAGCATCATTAAAATAAAGGGGCTCTTCTGGTTTTAGAGTGCATTGATTAGCTCGCCGAGGGTTCAGGCGTGGCACTA
CGCGGAGTAGGACATTTTCA

Product: putative glutathione peroxidase

Products: glutathione disulfide; H2O

Alternate protein names: NA

Number of amino acids: Translated: 156; Mature: 155

Protein sequence:

>156_residues
MSILDTEVTLINGEKASMDQWAGHCLLIVNTASECGYTPQLETLEELYEDYAMRGFFVIGVPCNQFGEEEPGKDAQVARR
YEEKFGVRFPLLAKSDVNGPNTIELYKKLKGDGPDIEWNFEKFIVAPSGEVVGRFAPSLDPDDMKIINVLEEYLPI

Sequences:

>Translated_156_residues
MSILDTEVTLINGEKASMDQWAGHCLLIVNTASECGYTPQLETLEELYEDYAMRGFFVIGVPCNQFGEEEPGKDAQVARR
YEEKFGVRFPLLAKSDVNGPNTIELYKKLKGDGPDIEWNFEKFIVAPSGEVVGRFAPSLDPDDMKIINVLEEYLPI
>Mature_155_residues
SILDTEVTLINGEKASMDQWAGHCLLIVNTASECGYTPQLETLEELYEDYAMRGFFVIGVPCNQFGEEEPGKDAQVARRY
EEKFGVRFPLLAKSDVNGPNTIELYKKLKGDGPDIEWNFEKFIVAPSGEVVGRFAPSLDPDDMKIINVLEEYLPI

Specific function: Not Essential For B12 Transport; However, It Is An Auxiliary Component Of The Transport System. [C]

COG id: COG0386

COG function: function code O; Glutathione peroxidase

Gene ontology:

Cell location: Periplasmic Protein [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glutathione peroxidase family [H]

Homologues:

Organism=Homo sapiens, GI15618997, Length=143, Percent_Identity=34.2657342657343, Blast_Score=99, Evalue=1e-21,
Organism=Homo sapiens, GI4557629, Length=180, Percent_Identity=32.7777777777778, Blast_Score=85, Evalue=2e-17,
Organism=Homo sapiens, GI75709200, Length=139, Percent_Identity=32.3741007194245, Blast_Score=84, Evalue=7e-17,
Organism=Homo sapiens, GI90903240, Length=148, Percent_Identity=31.0810810810811, Blast_Score=82, Evalue=1e-16,
Organism=Homo sapiens, GI6006001, Length=171, Percent_Identity=32.7485380116959, Blast_Score=80, Evalue=6e-16,
Organism=Homo sapiens, GI192455698, Length=138, Percent_Identity=32.6086956521739, Blast_Score=78, Evalue=3e-15,
Organism=Homo sapiens, GI33186887, Length=154, Percent_Identity=32.4675324675325, Blast_Score=74, Evalue=7e-14,
Organism=Homo sapiens, GI90903238, Length=121, Percent_Identity=32.2314049586777, Blast_Score=70, Evalue=6e-13,
Organism=Homo sapiens, GI32967607, Length=183, Percent_Identity=28.4153005464481, Blast_Score=68, Evalue=4e-12,
Organism=Homo sapiens, GI41406084, Length=166, Percent_Identity=30.7228915662651, Blast_Score=67, Evalue=9e-12,
Organism=Escherichia coli, GI1788003, Length=167, Percent_Identity=42.5149700598802, Blast_Score=132, Evalue=1e-32,
Organism=Caenorhabditis elegans, GI17535473, Length=150, Percent_Identity=39.3333333333333, Blast_Score=104, Evalue=2e-23,
Organism=Caenorhabditis elegans, GI17506887, Length=149, Percent_Identity=38.255033557047, Blast_Score=101, Evalue=1e-22,
Organism=Caenorhabditis elegans, GI193210707, Length=163, Percent_Identity=37.4233128834356, Blast_Score=95, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI71993584, Length=149, Percent_Identity=34.8993288590604, Blast_Score=94, Evalue=4e-20,
Organism=Caenorhabditis elegans, GI193209493, Length=164, Percent_Identity=31.7073170731707, Blast_Score=82, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI17550320, Length=164, Percent_Identity=29.8780487804878, Blast_Score=79, Evalue=1e-15,
Organism=Saccharomyces cerevisiae, GI6319721, Length=149, Percent_Identity=44.2953020134228, Blast_Score=135, Evalue=3e-33,
Organism=Saccharomyces cerevisiae, GI6322228, Length=139, Percent_Identity=43.8848920863309, Blast_Score=122, Evalue=2e-29,
Organism=Saccharomyces cerevisiae, GI6322826, Length=149, Percent_Identity=38.255033557047, Blast_Score=105, Evalue=2e-24,
Organism=Drosophila melanogaster, GI24656767, Length=151, Percent_Identity=39.0728476821192, Blast_Score=101, Evalue=2e-22,
Organism=Drosophila melanogaster, GI24656772, Length=151, Percent_Identity=39.0728476821192, Blast_Score=100, Evalue=3e-22,
Organism=Drosophila melanogaster, GI24656777, Length=151, Percent_Identity=39.0728476821192, Blast_Score=100, Evalue=3e-22,
Organism=Drosophila melanogaster, GI85726443, Length=141, Percent_Identity=39.7163120567376, Blast_Score=97, Evalue=4e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000889
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF00255 GSHPx [H]

EC number: 1.11.1.9

Molecular weight: Translated: 17527; Mature: 17396

Theoretical pI: Translated: 4.11; Mature: 4.11

Prosite motif: PS00460 GLUTATHIONE_PEROXID_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSILDTEVTLINGEKASMDQWAGHCLLIVNTASECGYTPQLETLEELYEDYAMRGFFVIG
CCCCCCEEEEECCCCCCHHHHCCEEEEEEECHHHCCCCCCHHHHHHHHHHHHHCCEEEEE
VPCNQFGEEEPGKDAQVARRYEEKFGVRFPLLAKSDVNGPNTIELYKKLKGDGPDIEWNF
CCHHHCCCCCCCCHHHHHHHHHHHHCCCCCEEECCCCCCCCHHHHHHHHCCCCCCCEECC
EKFIVAPSGEVVGRFAPSLDPDDMKIINVLEEYLPI
EEEEECCCCCCCEEECCCCCCCHHHHHHHHHHHHCC
>Mature Secondary Structure 
SILDTEVTLINGEKASMDQWAGHCLLIVNTASECGYTPQLETLEELYEDYAMRGFFVIG
CCCCCEEEEECCCCCCHHHHCCEEEEEEECHHHCCCCCCHHHHHHHHHHHHHCCEEEEE
VPCNQFGEEEPGKDAQVARRYEEKFGVRFPLLAKSDVNGPNTIELYKKLKGDGPDIEWNF
CCHHHCCCCCCCCHHHHHHHHHHHHCCCCCEEECCCCCCCCHHHHHHHHCCCCCCCEECC
EKFIVAPSGEVVGRFAPSLDPDDMKIINVLEEYLPI
EEEEECCCCCCCEEECCCCCCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: glutathione; H2O2

Specific reaction: 2 glutathione + H2O2 = glutathione disulfide + 2 H2O

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]