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The map label for this gene is mshD

Identifier: 38234479

GI number: 38234479

Start: 1964778

End: 1965689

Strand: Reverse

Name: mshD

Synonym: DIP1911

Alternate gene names: 38234479

Gene position: 1965689-1964778 (Counterclockwise)

Preceding gene: 38234481

Following gene: 38234478

Centisome position: 78.99

GC content: 55.04

Gene sequence:

>912_bases
ATGAAGATGATTGAAACCTCCTTAGCTTCAGCCTCGGCGGCTTTGCGTGATCGTGTCGATGAGATTCTTGCGGCGGCGAC
CCGCGAAGATGGTTGCGCACCGTTGTCAGAAAGTTTTCTCAATGGCCTTCGGCGGGCTGACGATGGCCACGTGCATTCTT
GTGTGATGGATAGCCACGACCAGGTGGTAGGGGTTGCAGCACGCGATGGGGATAGTGCTGAGGTGGTAGTGGATCCGGCA
TTCCGGCGCCAAGGCTATGGCAGCTTCCTTATCCGGCATGTGGTGTCCCAGGGGGTTAAGAATGTGTGGGCGCATGGTGA
TGGTGCGGGTGCAAAGGCGGTGGCAAAAGCACTGCAGTTGGAACAAACGCGTCAGTTGCTTGTGATGGCGGTCGAGGGGG
ATCGGCTTGTGGAGTCTGCGCAGTTGCAGGTTCCTAGTGGTTTTAGGGTGTTGGCGTTAAACGAGGCTTATGAGAGCATC
CCTGATATTGAGCAGCAGTGGTTGCGTGTGAATAACGAGGCTTTTGAGTGGCATCCTGAGCAGGGTGGTTGGGATAGTGC
TCGGTTGGCTCAGGCACGTGATACACAGTGGTTCCGGGAATCTGATGTGTTGTTTCTTATCGATACCGCCAAGCGCACTG
TTGCCGGTTTCCACTGGACGAAGCGCCACGGTGATCTGGCAGAAGGCGCCGATGGTGAGGTGTACGTTGTGGGACTAGGA
AGCGCTTATCGACGCCGCGGTTTGGGTGATTTGTTAATCCGCATGGGACTGCACCATTTGGAGTATGAACATGCGCGCCG
TGTGATCCTTTATGTTGAAGGCGATAATGAGTCGGCGCGTAGGGCTTATGATGCCCTAGGTTTCCACGTGGTTGAATCCC
ATGTGACGTATTCTCCGCAGTCTTCTTCATAG

Upstream 100 bases:

>100_bases
ATGGTGATGAGCAGGGCGTGGGCGCCACGACGGCGCGCTCGGGGGTCGGAGTCGTTGTGCACTCCTTTATTTTTACCACT
AGGTGCGTAGGGTGGGGCAC

Downstream 100 bases:

>100_bases
CGAGCCGCTAGGTAACGCACAGGTGAACAGAAAGGGGTTTCTGTTCACCTTTCTTATTGTGGGGGTGATAGGGGGTGGGT
GTTGTGGGAGGGGGAGTGGG

Product: putative acetyltransferase

Products: NA

Alternate protein names: MSH acetyltransferase; Mycothiol synthase

Number of amino acids: Translated: 303; Mature: 303

Protein sequence:

>303_residues
MKMIETSLASASAALRDRVDEILAAATREDGCAPLSESFLNGLRRADDGHVHSCVMDSHDQVVGVAARDGDSAEVVVDPA
FRRQGYGSFLIRHVVSQGVKNVWAHGDGAGAKAVAKALQLEQTRQLLVMAVEGDRLVESAQLQVPSGFRVLALNEAYESI
PDIEQQWLRVNNEAFEWHPEQGGWDSARLAQARDTQWFRESDVLFLIDTAKRTVAGFHWTKRHGDLAEGADGEVYVVGLG
SAYRRRGLGDLLIRMGLHHLEYEHARRVILYVEGDNESARRAYDALGFHVVESHVTYSPQSSS

Sequences:

>Translated_303_residues
MKMIETSLASASAALRDRVDEILAAATREDGCAPLSESFLNGLRRADDGHVHSCVMDSHDQVVGVAARDGDSAEVVVDPA
FRRQGYGSFLIRHVVSQGVKNVWAHGDGAGAKAVAKALQLEQTRQLLVMAVEGDRLVESAQLQVPSGFRVLALNEAYESI
PDIEQQWLRVNNEAFEWHPEQGGWDSARLAQARDTQWFRESDVLFLIDTAKRTVAGFHWTKRHGDLAEGADGEVYVVGLG
SAYRRRGLGDLLIRMGLHHLEYEHARRVILYVEGDNESARRAYDALGFHVVESHVTYSPQSSS
>Mature_303_residues
MKMIETSLASASAALRDRVDEILAAATREDGCAPLSESFLNGLRRADDGHVHSCVMDSHDQVVGVAARDGDSAEVVVDPA
FRRQGYGSFLIRHVVSQGVKNVWAHGDGAGAKAVAKALQLEQTRQLLVMAVEGDRLVESAQLQVPSGFRVLALNEAYESI
PDIEQQWLRVNNEAFEWHPEQGGWDSARLAQARDTQWFRESDVLFLIDTAKRTVAGFHWTKRHGDLAEGADGEVYVVGLG
SAYRRRGLGDLLIRMGLHHLEYEHARRVILYVEGDNESARRAYDALGFHVVESHVTYSPQSSS

Specific function: Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol

COG id: COG0456

COG function: function code R; Acetyltransferases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 2 N-acetyltransferase domains

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MSHD_CORDI (Q6NFH9)

Other databases:

- EMBL:   BX248359
- RefSeq:   NP_940246.1
- ProteinModelPortal:   Q6NFH9
- SMR:   Q6NFH9
- GeneID:   2648960
- GenomeReviews:   BX248353_GR
- KEGG:   cdi:DIP1911
- NMPDR:   fig|257309.1.peg.1837
- HOGENOM:   HBG292446
- OMA:   GFHWTKI
- ProtClustDB:   CLSK633864
- BioCyc:   CDIP257309:DIP1911-MONOMER
- HAMAP:   MF_01698
- InterPro:   IPR000182
- InterPro:   IPR016181
- InterPro:   IPR017813
- Gene3D:   G3DSA:3.40.630.30
- TIGRFAMs:   TIGR03448

Pfam domain/function: PF00583 Acetyltransf_1; SSF55729 Acyl_CoA_acyltransferase

EC number: =2.3.1.189

Molecular weight: Translated: 33489; Mature: 33489

Theoretical pI: Translated: 5.72; Mature: 5.72

Prosite motif: PS51186 GNAT

Important sites: BINDING 37-37 BINDING 180-180 BINDING 221-221 BINDING 233-233 BINDING 271-271

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKMIETSLASASAALRDRVDEILAAATREDGCAPLSESFLNGLRRADDGHVHSCVMDSHD
CCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCCEEEEEECCCC
QVVGVAARDGDSAEVVVDPAFRRQGYGSFLIRHVVSQGVKNVWAHGDGAGAKAVAKALQL
CEEEEEECCCCCCEEEECHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHH
EQTRQLLVMAVEGDRLVESAQLQVPSGFRVLALNEAYESIPDIEQQWLRVNNEAFEWHPE
HHHHEEEEEEECCCHHHHHHEEECCCCCEEEEECHHHHHCCCHHHHHHHCCCCCEEEECC
QGGWDSARLAQARDTQWFRESDVLFLIDTAKRTVAGFHWTKRHGDLAEGADGEVYVVGLG
CCCCCHHHHHHHHCCHHHCCCCEEEEEECCCHHHHCCEEECCCCCCCCCCCCCEEEEECC
SAYRRRGLGDLLIRMGLHHLEYEHARRVILYVEGDNESARRAYDALGFHVVESHVTYSPQ
HHHHHCCHHHHHHHHHHHHHCHHCCCEEEEEEECCCHHHHHHHHHHHHHHHHHCEECCCC
SSS
CCC
>Mature Secondary Structure
MKMIETSLASASAALRDRVDEILAAATREDGCAPLSESFLNGLRRADDGHVHSCVMDSHD
CCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCCEEEEEECCCC
QVVGVAARDGDSAEVVVDPAFRRQGYGSFLIRHVVSQGVKNVWAHGDGAGAKAVAKALQL
CEEEEEECCCCCCEEEECHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHH
EQTRQLLVMAVEGDRLVESAQLQVPSGFRVLALNEAYESIPDIEQQWLRVNNEAFEWHPE
HHHHEEEEEEECCCHHHHHHEEECCCCCEEEEECHHHHHCCCHHHHHHHCCCCCEEEECC
QGGWDSARLAQARDTQWFRESDVLFLIDTAKRTVAGFHWTKRHGDLAEGADGEVYVVGLG
CCCCCHHHHHHHHCCHHHCCCCEEEEEECCCHHHHCCEEECCCCCCCCCCCCCEEEEECC
SAYRRRGLGDLLIRMGLHHLEYEHARRVILYVEGDNESARRAYDALGFHVVESHVTYSPQ
HHHHHCCHHHHHHHHHHHHHCHHCCCEEEEEEECCCHHHHHHHHHHHHHHHHHCEECCCC
SSS
CCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 14602910