Click here to switch to the map view.

The map label for this gene is hflX [H]

Identifier: 38234020

GI number: 38234020

Start: 1458338

End: 1459948

Strand: Reverse

Name: hflX [H]

Synonym: DIP1439

Alternate gene names: 38234020

Gene position: 1459948-1458338 (Counterclockwise)

Preceding gene: 38234023

Following gene: 38234019

Centisome position: 58.66

GC content: 49.66

Gene sequence:

>1611_bases
ATGACAAATAATACTTTTAAGAACTCGGAACTTGGCGCACAGTCTCACATTCTTGCTGGTCAAGGGGAGAAAAACTATAG
CTCACATGATGAGCTTTTGGCACGTGCGTTTCGCGATCATAAACCTGTGAGCCGCTCTGCGGATGACGGCGAAGACTTTA
CTGGCTTGATTGCGACAAAATCGGTGTCGGAAGGTCATACGAATGTGTCTGACCACACACCGACTGTCGGCGAATTAGAT
CTGGAAGCTCGATCGAGTTTAAGATCGTTGACGCGTGGCTCAGAGATCCATGCAACCGATCAGGATGACGGTTATGACGT
CGAATATCGTAAGTTACGCTTGGAACGCGTCATCCTAGTAGGGGTGTGGACCAAGGGGACGACTGCAGAGATCGAAGCGA
ATATGAATGAATTGGCTTCGCTGGCGGAGACTGCAGGTGCAGACGTTGTCGAAGTCTTGTACCAAAAGCGTGATAAGCCC
GACCCAGGAACTTATATTGGTTCCGGCAAGGTGTCGGAACTCAAGGAAATAGTGTCGTCGACAGGCGTCGATACGGTTAT
TTGCGATGGTGAGCTTTCGCCGAGTCAGATGATTGCTCTGGAAAAGGCTCTCGATGTCAAAGTCATCGATCGTACAATGT
TGATTTTGGACATTTTCGCTCAACATGCGAAATCCAAAGAAGGTAAAGCTCAAGTAAGTTTGGCTCAGATGGAGTACCTC
ATTACTCGAGTGCGTGGTTGGGGTGGGGCGCTATCGCGTCAGGCTGGTGGTCGTGCCGGATCCAATGGCGGTGTTGGTCT
TCGTGGCCCTGGCGAGACAAAGATCGAAGCAGATCGGCGACGCTTGCGTTCTGATATGGCTAAACTGCGCAAAGAGATCG
CGGGTATGAAGACGGCTCGTGAGGTGAAACGGTCGCAGCGAAAGCAGTCAACGATTCCTCAAATTGCCATTGCTGGATAT
ACCAATGCTGGAAAATCTTCGCTTATCAACGCAATGACCGGTGCTGGTGTCTTGGTAGAAGATGCTTTGTTTGCAACGTT
GGATCCAACAACACGACGTGCGGAGCTTGCAGATGGTCGCGCAGTTGTGTTTACGGATACGGTTGGCTTTGTGCGTCACC
TACCGACTCAATTAGTCGAGTCGTTTAGATCCACCTTGGAAGAGGTCGTTGATGCTGATCTCGTCCTGCATGTTGTTGAT
GGGTCTGATCCATTTCCGCTCAAACAAATCGAAGCCGTAAATACGGTGGTATCGGAAATTGTTCGTGAACTTAAGGTAGA
TGCGCCTCCAGAGATCATTGTGGTCAATAAAATTGACCAAGCTGACCCATTAGTTTTGGCTGAGCTGCGTCATGCTCTTG
ATGATGTGGTCTTCGTATCTGCGAAGACGGCAGAAGGAATACCCGAGCTAGAAATGCGGGTAGAACAGTTTCTTAATACC
CTAGATACTCATGTGCGATTGCTCGTTCCATACACTCGGGGAGATATCGTGTCGCGTCTCCACAGCAATGGCACGGTTCT
CAGCGAAGAATATGAAGCAGAAGGCACGCTTATCGACGTCCGGTTACCAGCTGCTATTGCGGCGGAACTAGGTGAGCTAC
GAGTTGATTAA

Upstream 100 bases:

>100_bases
GGCTTTGTTGAAGGTGGGCGATTAGGTCGTTCGCTGTCAGCGAGAATTCTCGTAAAAAGGTGGCTGCACCATCAAGAAAC
TGGAAGAATGTGTAACAACG

Downstream 100 bases:

>100_bases
GCACCTGACTTCATCTGCAATGGGGTAGACCCATGATGTTGTATTTGTTTTATTCCTTGTGTGGGAGCCATAATGAGGTT
TCGTGAGTACAGCATCTTGG

Product: putative GTP-binding protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 536; Mature: 535

Protein sequence:

>536_residues
MTNNTFKNSELGAQSHILAGQGEKNYSSHDELLARAFRDHKPVSRSADDGEDFTGLIATKSVSEGHTNVSDHTPTVGELD
LEARSSLRSLTRGSEIHATDQDDGYDVEYRKLRLERVILVGVWTKGTTAEIEANMNELASLAETAGADVVEVLYQKRDKP
DPGTYIGSGKVSELKEIVSSTGVDTVICDGELSPSQMIALEKALDVKVIDRTMLILDIFAQHAKSKEGKAQVSLAQMEYL
ITRVRGWGGALSRQAGGRAGSNGGVGLRGPGETKIEADRRRLRSDMAKLRKEIAGMKTAREVKRSQRKQSTIPQIAIAGY
TNAGKSSLINAMTGAGVLVEDALFATLDPTTRRAELADGRAVVFTDTVGFVRHLPTQLVESFRSTLEEVVDADLVLHVVD
GSDPFPLKQIEAVNTVVSEIVRELKVDAPPEIIVVNKIDQADPLVLAELRHALDDVVFVSAKTAEGIPELEMRVEQFLNT
LDTHVRLLVPYTRGDIVSRLHSNGTVLSEEYEAEGTLIDVRLPAAIAAELGELRVD

Sequences:

>Translated_536_residues
MTNNTFKNSELGAQSHILAGQGEKNYSSHDELLARAFRDHKPVSRSADDGEDFTGLIATKSVSEGHTNVSDHTPTVGELD
LEARSSLRSLTRGSEIHATDQDDGYDVEYRKLRLERVILVGVWTKGTTAEIEANMNELASLAETAGADVVEVLYQKRDKP
DPGTYIGSGKVSELKEIVSSTGVDTVICDGELSPSQMIALEKALDVKVIDRTMLILDIFAQHAKSKEGKAQVSLAQMEYL
ITRVRGWGGALSRQAGGRAGSNGGVGLRGPGETKIEADRRRLRSDMAKLRKEIAGMKTAREVKRSQRKQSTIPQIAIAGY
TNAGKSSLINAMTGAGVLVEDALFATLDPTTRRAELADGRAVVFTDTVGFVRHLPTQLVESFRSTLEEVVDADLVLHVVD
GSDPFPLKQIEAVNTVVSEIVRELKVDAPPEIIVVNKIDQADPLVLAELRHALDDVVFVSAKTAEGIPELEMRVEQFLNT
LDTHVRLLVPYTRGDIVSRLHSNGTVLSEEYEAEGTLIDVRLPAAIAAELGELRVD
>Mature_535_residues
TNNTFKNSELGAQSHILAGQGEKNYSSHDELLARAFRDHKPVSRSADDGEDFTGLIATKSVSEGHTNVSDHTPTVGELDL
EARSSLRSLTRGSEIHATDQDDGYDVEYRKLRLERVILVGVWTKGTTAEIEANMNELASLAETAGADVVEVLYQKRDKPD
PGTYIGSGKVSELKEIVSSTGVDTVICDGELSPSQMIALEKALDVKVIDRTMLILDIFAQHAKSKEGKAQVSLAQMEYLI
TRVRGWGGALSRQAGGRAGSNGGVGLRGPGETKIEADRRRLRSDMAKLRKEIAGMKTAREVKRSQRKQSTIPQIAIAGYT
NAGKSSLINAMTGAGVLVEDALFATLDPTTRRAELADGRAVVFTDTVGFVRHLPTQLVESFRSTLEEVVDADLVLHVVDG
SDPFPLKQIEAVNTVVSEIVRELKVDAPPEIIVVNKIDQADPLVLAELRHALDDVVFVSAKTAEGIPELEMRVEQFLNTL
DTHVRLLVPYTRGDIVSRLHSNGTVLSEEYEAEGTLIDVRLPAAIAAELGELRVD

Specific function: Unknown

COG id: COG2262

COG function: function code R; GTPases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 G (guanine nucleotide-binding) domain [H]

Homologues:

Organism=Homo sapiens, GI310124269, Length=207, Percent_Identity=38.1642512077295, Blast_Score=121, Evalue=2e-27,
Organism=Homo sapiens, GI310124267, Length=207, Percent_Identity=38.1642512077295, Blast_Score=121, Evalue=2e-27,
Organism=Homo sapiens, GI310124171, Length=207, Percent_Identity=38.1642512077295, Blast_Score=121, Evalue=2e-27,
Organism=Homo sapiens, GI310124169, Length=207, Percent_Identity=38.1642512077295, Blast_Score=121, Evalue=2e-27,
Organism=Homo sapiens, GI310133116, Length=215, Percent_Identity=38.1395348837209, Blast_Score=120, Evalue=3e-27,
Organism=Homo sapiens, GI310133118, Length=215, Percent_Identity=38.1395348837209, Blast_Score=120, Evalue=4e-27,
Organism=Escherichia coli, GI1790615, Length=419, Percent_Identity=40.3341288782816, Blast_Score=280, Evalue=2e-76,
Organism=Caenorhabditis elegans, GI17561038, Length=291, Percent_Identity=34.3642611683849, Blast_Score=134, Evalue=1e-31,
Organism=Drosophila melanogaster, GI24650079, Length=371, Percent_Identity=32.6145552560647, Blast_Score=132, Evalue=6e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009022
- InterPro:   IPR016496
- InterPro:   IPR006073
- InterPro:   IPR002917 [H]

Pfam domain/function: PF01926 MMR_HSR1 [H]

EC number: NA

Molecular weight: Translated: 58250; Mature: 58118

Theoretical pI: Translated: 4.97; Mature: 4.97

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTNNTFKNSELGAQSHILAGQGEKNYSSHDELLARAFRDHKPVSRSADDGEDFTGLIATK
CCCCCCCCCCCCCCCCEECCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEEC
SVSEGHTNVSDHTPTVGELDLEARSSLRSLTRGSEIHATDQDDGYDVEYRKLRLERVILV
CCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCEEECCCCCCCCHHHHHHHEEEEEEE
GVWTKGTTAEIEANMNELASLAETAGADVVEVLYQKRDKPDPGTYIGSGKVSELKEIVSS
EEECCCCCEEECCCHHHHHHHHHHCCHHHHHHHHHHCCCCCCCCEECCCCHHHHHHHHHH
TGVDTVICDGELSPSQMIALEKALDVKVIDRTMLILDIFAQHAKSKEGKAQVSLAQMEYL
CCCCEEEECCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHH
ITRVRGWGGALSRQAGGRAGSNGGVGLRGPGETKIEADRRRLRSDMAKLRKEIAGMKTAR
HHHHHCCCCHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCHHHHH
EVKRSQRKQSTIPQIAIAGYTNAGKSSLINAMTGAGVLVEDALFATLDPTTRRAELADGR
HHHHHHHHHHCCCEEEEECCCCCCHHHHHHHHHCCCHHHHHHHHHCCCCCCCHHHHCCCC
AVVFTDTVGFVRHLPTQLVESFRSTLEEVVDADLVLHVVDGSDPFPLKQIEAVNTVVSEI
EEEEECCHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCHHHHHHHHHHHHHH
VRELKVDAPPEIIVVNKIDQADPLVLAELRHALDDVVFVSAKTAEGIPELEMRVEQFLNT
HHHHCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHEEEEEECCCCCCHHHHHHHHHHHHH
LDTHVRLLVPYTRGDIVSRLHSNGTVLSEEYEAEGTLIDVRLPAAIAAELGELRVD
HHCCEEEEEECCHHHHHHHHHCCCCEECCCCCCCCCEEEEECCHHHHHHHHHHCCC
>Mature Secondary Structure 
TNNTFKNSELGAQSHILAGQGEKNYSSHDELLARAFRDHKPVSRSADDGEDFTGLIATK
CCCCCCCCCCCCCCCEECCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEEC
SVSEGHTNVSDHTPTVGELDLEARSSLRSLTRGSEIHATDQDDGYDVEYRKLRLERVILV
CCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCEEECCCCCCCCHHHHHHHEEEEEEE
GVWTKGTTAEIEANMNELASLAETAGADVVEVLYQKRDKPDPGTYIGSGKVSELKEIVSS
EEECCCCCEEECCCHHHHHHHHHHCCHHHHHHHHHHCCCCCCCCEECCCCHHHHHHHHHH
TGVDTVICDGELSPSQMIALEKALDVKVIDRTMLILDIFAQHAKSKEGKAQVSLAQMEYL
CCCCEEEECCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHH
ITRVRGWGGALSRQAGGRAGSNGGVGLRGPGETKIEADRRRLRSDMAKLRKEIAGMKTAR
HHHHHCCCCHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCHHHHH
EVKRSQRKQSTIPQIAIAGYTNAGKSSLINAMTGAGVLVEDALFATLDPTTRRAELADGR
HHHHHHHHHHCCCEEEEECCCCCCHHHHHHHHHCCCHHHHHHHHHCCCCCCCHHHHCCCC
AVVFTDTVGFVRHLPTQLVESFRSTLEEVVDADLVLHVVDGSDPFPLKQIEAVNTVVSEI
EEEEECCHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCHHHHHHHHHHHHHH
VRELKVDAPPEIIVVNKIDQADPLVLAELRHALDDVVFVSAKTAEGIPELEMRVEQFLNT
HHHHCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHEEEEEECCCCCCHHHHHHHHHHHHH
LDTHVRLLVPYTRGDIVSRLHSNGTVLSEEYEAEGTLIDVRLPAAIAAELGELRVD
HHCCEEEEEECCHHHHHHHHHCCCCEECCCCCCCCCEEEEECCHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8248183; 7610040; 9278503; 2020545; 3040675 [H]