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The map label for this gene is glpR [H]

Identifier: 38234014

GI number: 38234014

Start: 1450500

End: 1451303

Strand: Direct

Name: glpR [H]

Synonym: DIP1429

Alternate gene names: 38234014

Gene position: 1450500-1451303 (Clockwise)

Preceding gene: 38234012

Following gene: 38234015

Centisome position: 58.28

GC content: 50.25

Gene sequence:

>804_bases
GTGGCTACCGTAGAAGAAGTAAATCTGCGCCAAGCAACCATCGTTTCGCTCACCAATGAAACAGGACGATCAAGTGTAAC
GCAGCTAGCTCAGCAATTTGATGTTACGCCTGAAACCATCAGACGCGACCTGAAAAGTCTCGAGCAACAGGGGCTCCTTC
GACGTGTTCATGGGGGAGCTGTTTCCGGTAGTCCCAAACTTAACGTCGATGTGTTCGCTGTAGACGATGACGATGATCTG
CCAATTCATCAATCGCAGCGACGCAAGCAAAGCATCGCTTTAACTGCCCTATCGCTTATTCCTGGCCCTGAAGCATCAAT
CTTTATAGATGCCGGTTCAACTACCGAAACTTTTGCCAACGTTTTAGCCCGTACATACTTAGGACAAAATTGGCTCGTCG
TTACTACTTCGCCGAACGTCGCAAGAACGTTGAGTAGTGCCGGCGTCCCTGATGTCATCATGGTCGGCGGTTTTGTAAAG
GCACGCACCCAGGCAATTGTTGGCCCCCACGCCATAGAAACGTTGCACTCTATGAGGGCAGATATCGCCTTTTTAGGAAC
TAACGGGATTGACCCACACAAAGGTTTTACAACTTCAGATGAGCGTGAAGCCAAGGTGAAGCACGAGATGATCGCCCACG
CCCAAACATCTGTCATTCTCTGTGATTCCGGAAAAATCGGGCACAGTTCTGCGGTCAGTTTTGCGCAGCTTGCCGATGTT
GACTTTGTTGTTACTGATCGCAACTCTCCTCCTCAGCTTTCCCGCCAGCTCGGCGAACCCAATTTACAAGTGGTGATCCC
GTGA

Upstream 100 bases:

>100_bases
CATCATAAAACGAAGGATTTTTTGCCGTTACATAACAGCAATATGCCCTCAAAATTCTATTGGGGGTTAAAAGAATTCTT
GGTTCAATGAAGGAGTGAAG

Downstream 100 bases:

>100_bases
TTCTGACGTTTACCCCAAATCCCAGCATCGATAAGACCCTCCAGTTGGATTCCGTACTTACTCGAGGCGCAGTACAACGC
TTATCAGGCGTACAAACAGT

Product: putative sugar related operon transcriptional regulator (PTS system)

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 267; Mature: 266

Protein sequence:

>267_residues
MATVEEVNLRQATIVSLTNETGRSSVTQLAQQFDVTPETIRRDLKSLEQQGLLRRVHGGAVSGSPKLNVDVFAVDDDDDL
PIHQSQRRKQSIALTALSLIPGPEASIFIDAGSTTETFANVLARTYLGQNWLVVTTSPNVARTLSSAGVPDVIMVGGFVK
ARTQAIVGPHAIETLHSMRADIAFLGTNGIDPHKGFTTSDEREAKVKHEMIAHAQTSVILCDSGKIGHSSAVSFAQLADV
DFVVTDRNSPPQLSRQLGEPNLQVVIP

Sequences:

>Translated_267_residues
MATVEEVNLRQATIVSLTNETGRSSVTQLAQQFDVTPETIRRDLKSLEQQGLLRRVHGGAVSGSPKLNVDVFAVDDDDDL
PIHQSQRRKQSIALTALSLIPGPEASIFIDAGSTTETFANVLARTYLGQNWLVVTTSPNVARTLSSAGVPDVIMVGGFVK
ARTQAIVGPHAIETLHSMRADIAFLGTNGIDPHKGFTTSDEREAKVKHEMIAHAQTSVILCDSGKIGHSSAVSFAQLADV
DFVVTDRNSPPQLSRQLGEPNLQVVIP
>Mature_266_residues
ATVEEVNLRQATIVSLTNETGRSSVTQLAQQFDVTPETIRRDLKSLEQQGLLRRVHGGAVSGSPKLNVDVFAVDDDDDLP
IHQSQRRKQSIALTALSLIPGPEASIFIDAGSTTETFANVLARTYLGQNWLVVTTSPNVARTLSSAGVPDVIMVGGFVKA
RTQAIVGPHAIETLHSMRADIAFLGTNGIDPHKGFTTSDEREAKVKHEMIAHAQTSVILCDSGKIGHSSAVSFAQLADVD
FVVTDRNSPPQLSRQLGEPNLQVVIP

Specific function: Repressor of the glycerol-3-phosphate regulon [H]

COG id: COG1349

COG function: function code KG; Transcriptional regulators of sugar metabolism

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH deoR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789829, Length=249, Percent_Identity=30.9236947791165, Blast_Score=113, Evalue=1e-26,
Organism=Escherichia coli, GI87082344, Length=261, Percent_Identity=29.8850574712644, Blast_Score=109, Evalue=2e-25,
Organism=Escherichia coli, GI1787540, Length=241, Percent_Identity=31.1203319502075, Blast_Score=105, Evalue=3e-24,
Organism=Escherichia coli, GI1789059, Length=262, Percent_Identity=32.824427480916, Blast_Score=105, Evalue=3e-24,
Organism=Escherichia coli, GI1789519, Length=260, Percent_Identity=27.3076923076923, Blast_Score=102, Evalue=3e-23,
Organism=Escherichia coli, GI1788069, Length=250, Percent_Identity=28, Blast_Score=89, Evalue=4e-19,
Organism=Escherichia coli, GI226510968, Length=257, Percent_Identity=28.4046692607004, Blast_Score=86, Evalue=2e-18,
Organism=Escherichia coli, GI1790635, Length=253, Percent_Identity=24.1106719367589, Blast_Score=75, Evalue=6e-15,
Organism=Escherichia coli, GI1789170, Length=241, Percent_Identity=28.2157676348548, Blast_Score=72, Evalue=4e-14,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014036
- InterPro:   IPR001034
- InterPro:   IPR018356
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00455 DeoR; PF08220 HTH_DeoR [H]

EC number: NA

Molecular weight: Translated: 28681; Mature: 28550

Theoretical pI: Translated: 6.09; Mature: 6.09

Prosite motif: PS51000 HTH_DEOR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATVEEVNLRQATIVSLTNETGRSSVTQLAQQFDVTPETIRRDLKSLEQQGLLRRVHGGA
CCCHHHCCCCEEEEEEEECCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCC
VSGSPKLNVDVFAVDDDDDLPIHQSQRRKQSIALTALSLIPGPEASIFIDAGSTTETFAN
CCCCCCCEEEEEEECCCCCCCCCHHHHHHHHHHHHHEECCCCCCCEEEEECCCCHHHHHH
VLARTYLGQNWLVVTTSPNVARTLSSAGVPDVIMVGGFVKARTQAIVGPHAIETLHSMRA
HHHHHHCCCCEEEEECCCHHHHHHHHCCCCCEEEECCHHHHHHHHHCCHHHHHHHHHHHH
DIAFLGTNGIDPHKGFTTSDEREAKVKHEMIAHAQTSVILCDSGKIGHSSAVSFAQLADV
CEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHCCCEEEEECCCCCCCHHHHHHHHHCCE
DFVVTDRNSPPQLSRQLGEPNLQVVIP
EEEEECCCCCHHHHHHHCCCCEEEECC
>Mature Secondary Structure 
ATVEEVNLRQATIVSLTNETGRSSVTQLAQQFDVTPETIRRDLKSLEQQGLLRRVHGGA
CCHHHCCCCEEEEEEEECCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCC
VSGSPKLNVDVFAVDDDDDLPIHQSQRRKQSIALTALSLIPGPEASIFIDAGSTTETFAN
CCCCCCCEEEEEEECCCCCCCCCHHHHHHHHHHHHHEECCCCCCCEEEEECCCCHHHHHH
VLARTYLGQNWLVVTTSPNVARTLSSAGVPDVIMVGGFVKARTQAIVGPHAIETLHSMRA
HHHHHHCCCCEEEEECCCHHHHHHHHCCCCCEEEECCHHHHHHHHHCCHHHHHHHHHHHH
DIAFLGTNGIDPHKGFTTSDEREAKVKHEMIAHAQTSVILCDSGKIGHSSAVSFAQLADV
CEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHCCCEEEEECCCCCCCHHHHHHHHHCCE
DFVVTDRNSPPQLSRQLGEPNLQVVIP
EEEEECCCCCHHHHHHHCCCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8752340; 10984043 [H]