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The map label for this gene is gatR [H]

Identifier: 38234012

GI number: 38234012

Start: 1447668

End: 1448444

Strand: Direct

Name: gatR [H]

Synonym: DIP1427

Alternate gene names: 38234012

Gene position: 1447668-1448444 (Clockwise)

Preceding gene: 38234011

Following gene: 38234014

Centisome position: 58.17

GC content: 49.68

Gene sequence:

>777_bases
ATGTATTCCGAGGAGCGCCGCAGGCAAATTGCCTCTTTGACTGCAGTTGAAGGCCGCGTCAACGTAACAGAGCTAGCAGC
ACGCTTCGACGTGACAGCAGAGACTATCCGTAGGGATTTAGCAGTCTTAGATAGAGAAGGAGTGGTCCACCGAGTACACG
GTGGGGCTGTCGCAAACCAAACATTTCAAACTGCCGAATTTAGCTTGGATACGCGATCACGCTCTGCGTCTGGTGCTAAA
AATTCCATCGCGCACGCAGCCCTTAGTTATCTTCCTGAAGCTCAGGGAGGTCTGTTTCTTGATGCCGGAACGACCACCGC
TGCATTAGCCGAACTCCTAGCAGCCCAACCATTTGCAAAACACTGGTCCATCGTTACCAATAGCTTGTCAATCGCACTTA
CCTTGGCGAATTCCGGCCTTGACGAAATCCAACTCCTCGGTGGCAGTGTCAGGGCCATTACCCAAGCCGTCGTTGGCGAT
ACTGCTCTTCGTACTTTGGCGCTCATGCGAGCCGATGTTGCCTTCATCGGTACAAACGCATTGACAATCGATCACGGACT
ATCGACTGCAGATTCACAAGAGGCTGCTATTAAGTCTGCAATGATTACTAATGCACATAAAGTTGTTGTTTTGTGCGATT
CGACCAAAATGGGCACTGATTACTTGGTAAGTTTTGGATCTATTTCTGATATTGATGTCATCATCACTGACGCTAATGCC
CCTGAGAGCTTTGTGAAAGCACTGCGCGACCGTGATGTGGAAGTCATTATCGCCTAG

Upstream 100 bases:

>100_bases
TTGGTTTTTGCATGAAAAGATAGAAGGAGGATAAATACAAAAACCAAAAGTCCTCAATCTCGGCTTTGCCCGATCTATTG
ATCCACGAAAGGTCAAACCA

Downstream 100 bases:

>100_bases
CTTCAATCTTTCAAGTTTTCTCATCATAATTAATGAAGTGGGGCGGGAAGAACTTTTGTTCTTCCCGCCCCACTTCATTA
ACGTTGCTCGAGCTTAAGGC

Product: putative sugar related operon transcriptional regulator (PTS system)

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 258; Mature: 258

Protein sequence:

>258_residues
MYSEERRRQIASLTAVEGRVNVTELAARFDVTAETIRRDLAVLDREGVVHRVHGGAVANQTFQTAEFSLDTRSRSASGAK
NSIAHAALSYLPEAQGGLFLDAGTTTAALAELLAAQPFAKHWSIVTNSLSIALTLANSGLDEIQLLGGSVRAITQAVVGD
TALRTLALMRADVAFIGTNALTIDHGLSTADSQEAAIKSAMITNAHKVVVLCDSTKMGTDYLVSFGSISDIDVIITDANA
PESFVKALRDRDVEVIIA

Sequences:

>Translated_258_residues
MYSEERRRQIASLTAVEGRVNVTELAARFDVTAETIRRDLAVLDREGVVHRVHGGAVANQTFQTAEFSLDTRSRSASGAK
NSIAHAALSYLPEAQGGLFLDAGTTTAALAELLAAQPFAKHWSIVTNSLSIALTLANSGLDEIQLLGGSVRAITQAVVGD
TALRTLALMRADVAFIGTNALTIDHGLSTADSQEAAIKSAMITNAHKVVVLCDSTKMGTDYLVSFGSISDIDVIITDANA
PESFVKALRDRDVEVIIA
>Mature_258_residues
MYSEERRRQIASLTAVEGRVNVTELAARFDVTAETIRRDLAVLDREGVVHRVHGGAVANQTFQTAEFSLDTRSRSASGAK
NSIAHAALSYLPEAQGGLFLDAGTTTAALAELLAAQPFAKHWSIVTNSLSIALTLANSGLDEIQLLGGSVRAITQAVVGD
TALRTLALMRADVAFIGTNALTIDHGLSTADSQEAAIKSAMITNAHKVVVLCDSTKMGTDYLVSFGSISDIDVIITDANA
PESFVKALRDRDVEVIIA

Specific function: Repressor of the gat operon for galacticol transport and metabolism [H]

COG id: COG1349

COG function: function code KG; Transcriptional regulators of sugar metabolism

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH deoR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789519, Length=256, Percent_Identity=32.421875, Blast_Score=125, Evalue=3e-30,
Organism=Escherichia coli, GI1789829, Length=255, Percent_Identity=30.9803921568627, Blast_Score=116, Evalue=1e-27,
Organism=Escherichia coli, GI87082344, Length=254, Percent_Identity=30.3149606299213, Blast_Score=115, Evalue=2e-27,
Organism=Escherichia coli, GI1789059, Length=259, Percent_Identity=31.2741312741313, Blast_Score=110, Evalue=6e-26,
Organism=Escherichia coli, GI226510968, Length=258, Percent_Identity=32.9457364341085, Blast_Score=102, Evalue=3e-23,
Organism=Escherichia coli, GI1788069, Length=263, Percent_Identity=29.6577946768061, Blast_Score=97, Evalue=9e-22,
Organism=Escherichia coli, GI1787540, Length=234, Percent_Identity=28.2051282051282, Blast_Score=82, Evalue=3e-17,
Organism=Escherichia coli, GI1790753, Length=217, Percent_Identity=26.2672811059908, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1790635, Length=255, Percent_Identity=26.2745098039216, Blast_Score=69, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014036
- InterPro:   IPR001034
- InterPro:   IPR018356
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00455 DeoR; PF08220 HTH_DeoR [H]

EC number: NA

Molecular weight: Translated: 27310; Mature: 27310

Theoretical pI: Translated: 5.10; Mature: 5.10

Prosite motif: PS51000 HTH_DEOR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYSEERRRQIASLTAVEGRVNVTELAARFDVTAETIRRDLAVLDREGVVHRVHGGAVANQ
CCCHHHHHHHHHHHHHCCCCCHHHHHHHHCCCHHHHHHHHHHHCCCCCEEEECCCCHHCC
TFQTAEFSLDTRSRSASGAKNSIAHAALSYLPEAQGGLFLDAGTTTAALAELLAAQPFAK
CCHHHEEEECCCCCCCCCCHHHHHHHHHHHCCCCCCCEEEECCCHHHHHHHHHHCCCHHH
HWSIVTNSLSIALTLANSGLDEIQLLGGSVRAITQAVVGDTALRTLALMRADVAFIGTNA
HHHHHCCCEEEEEEEECCCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCE
LTIDHGLSTADSQEAAIKSAMITNAHKVVVLCDSTKMGTDYLVSFGSISDIDVIITDANA
EEEECCCCCCCCHHHHHHHHHHCCCCEEEEEECCCCCCHHHEEECCCCCCEEEEEECCCC
PESFVKALRDRDVEVIIA
CHHHHHHHHCCCEEEEEC
>Mature Secondary Structure
MYSEERRRQIASLTAVEGRVNVTELAARFDVTAETIRRDLAVLDREGVVHRVHGGAVANQ
CCCHHHHHHHHHHHHHCCCCCHHHHHHHHCCCHHHHHHHHHHHCCCCCEEEECCCCHHCC
TFQTAEFSLDTRSRSASGAKNSIAHAALSYLPEAQGGLFLDAGTTTAALAELLAAQPFAK
CCHHHEEEECCCCCCCCCCHHHHHHHHHHHCCCCCCCEEEECCCHHHHHHHHHHCCCHHH
HWSIVTNSLSIALTLANSGLDEIQLLGGSVRAITQAVVGDTALRTLALMRADVAFIGTNA
HHHHHCCCEEEEEEEECCCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCE
LTIDHGLSTADSQEAAIKSAMITNAHKVVVLCDSTKMGTDYLVSFGSISDIDVIITDANA
EEEECCCCCCCCHHHHHHHHHHCCCCEEEEEECCCCCCHHHEEECCCCCCEEEEEECCCC
PESFVKALRDRDVEVIIA
CHHHHHHHHCCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9097040; 9278503; 7772602; 1661252 [H]