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The map label for this gene is aroC

Identifier: 38233931

GI number: 38233931

Start: 1357394

End: 1358605

Strand: Reverse

Name: aroC

Synonym: DIP1345

Alternate gene names: 38233931

Gene position: 1358605-1357394 (Counterclockwise)

Preceding gene: 38233933

Following gene: 38233930

Centisome position: 54.59

GC content: 49.34

Gene sequence:

>1212_bases
ATGCTTCGTTGGACAACTGCTGGAGAATCACACGGACAAGCATTGATTGCAATGCTCGAACACATGCCCGCTGGTGTGCC
TATTAGCCGAGAGGAAATTTCCTTTCAACTAGGCAGACGGCGTCTTGGTTTTGGACGTGGGGCACGAATGAAATTTGAAG
CTGACGAGGTAAGCATTCTGGGTGGTGTTCGTCATGGGTATACGATTGGCAGCCCAATCGCAATTATGGTTGGAAACACT
GAGTGGCCAAAATGGACGACCATTATGTCTGCAGATGCAATTGACGAGTCTGATCCTGATGTTGCCGCAGCTATGTCTTC
TGGACGCGGAGCCCGTCTGACGCGGCCCCGTCCTGGACATGCTGATTTTGCAGGAATGGTCAAATATAATCATGATGAAG
CTCGACCGATTTTAGAGCGATCCTCAGCACGAGAGACTGCTGCGCGAGTAGCTGCAGCCACAGTTGCACGGAGCTTTCTG
CGTGAAACGCTTGGCGTGGAAGTATTCTCGCATGTTATTTCCATTGGTCGCTCGGAAATTGATCAAACAGTTTGCCCAAC
ATTTGAGGACTTAGGAAGGATTGATGATTCTCCTGTCCGTTCAGCTTCAGCACAAGCGGAAGCGAGCATGATAGATCAAA
TTAATGCAGCTAAAAAACAAGGAGATACCCTTGGCGGCATTGTTGAGGTCATCGTTAACGGCCTTCCTATCGGCTTAGGC
TCTCATATTTCAGGCGAGGATCGACTAGATGCACAGCTTGCAGCGGCCCTCATGGGCATCCAAGCAATAAAAGGCGTGGA
AATCGGTGACGGATTTGAAGAAGCCCGAAGGCTAGGTTCAGAAGCACATGATGAGATTGTGTTGAGGGACGGCGTAGTTG
CACGACAAAGTAACAGGGCAGGTGGCATCGAAGGTGGTATGACCAATGGAGAAAGCCTTCGAGTACGTGCAGCAATGAAG
CCAATTTCGACCGTGCCTCGAGCATTACAATCCATTGATATGGATTCTGGTAAACGTGCTACTGGAATCCATCAGCGATC
TGACGTATGTGCTGTTCCTGCAGCTGGTGTTGTTGCAGAAGCAATGGTTGCGTTGGTTTTAGCGCGAGCAGTGTTGGAAA
AATTTGGTGGCGATTCCTTAGCCGAGACGAAGCGAAATATCGCTGCTTATAACGAATACGTTAAAACCCGGATTGCATTC
GATGGTGAGTAG

Upstream 100 bases:

>100_bases
GGAGTCAAATTACCCCCACATAGTCAGTGTTTTACCCAGAAACAACAAGAAATCATATGCAAACCGATCTTCTTGTTCAT
GACATGCCATAATTTCAAGC

Downstream 100 bases:

>100_bases
GAAAATGATGAACGATCAGTTACTCGAATCAGACGTGAGTGGTCGGGTTCGCCCAATCGTTGTTTTAGTAGGTCCACCGG
GGTCAGGTAAAACGACTATT

Product: chorismate synthase

Products: NA

Alternate protein names: 5-enolpyruvylshikimate-3-phosphate phospholyase

Number of amino acids: Translated: 403; Mature: 403

Protein sequence:

>403_residues
MLRWTTAGESHGQALIAMLEHMPAGVPISREEISFQLGRRRLGFGRGARMKFEADEVSILGGVRHGYTIGSPIAIMVGNT
EWPKWTTIMSADAIDESDPDVAAAMSSGRGARLTRPRPGHADFAGMVKYNHDEARPILERSSARETAARVAAATVARSFL
RETLGVEVFSHVISIGRSEIDQTVCPTFEDLGRIDDSPVRSASAQAEASMIDQINAAKKQGDTLGGIVEVIVNGLPIGLG
SHISGEDRLDAQLAAALMGIQAIKGVEIGDGFEEARRLGSEAHDEIVLRDGVVARQSNRAGGIEGGMTNGESLRVRAAMK
PISTVPRALQSIDMDSGKRATGIHQRSDVCAVPAAGVVAEAMVALVLARAVLEKFGGDSLAETKRNIAAYNEYVKTRIAF
DGE

Sequences:

>Translated_403_residues
MLRWTTAGESHGQALIAMLEHMPAGVPISREEISFQLGRRRLGFGRGARMKFEADEVSILGGVRHGYTIGSPIAIMVGNT
EWPKWTTIMSADAIDESDPDVAAAMSSGRGARLTRPRPGHADFAGMVKYNHDEARPILERSSARETAARVAAATVARSFL
RETLGVEVFSHVISIGRSEIDQTVCPTFEDLGRIDDSPVRSASAQAEASMIDQINAAKKQGDTLGGIVEVIVNGLPIGLG
SHISGEDRLDAQLAAALMGIQAIKGVEIGDGFEEARRLGSEAHDEIVLRDGVVARQSNRAGGIEGGMTNGESLRVRAAMK
PISTVPRALQSIDMDSGKRATGIHQRSDVCAVPAAGVVAEAMVALVLARAVLEKFGGDSLAETKRNIAAYNEYVKTRIAF
DGE
>Mature_403_residues
MLRWTTAGESHGQALIAMLEHMPAGVPISREEISFQLGRRRLGFGRGARMKFEADEVSILGGVRHGYTIGSPIAIMVGNT
EWPKWTTIMSADAIDESDPDVAAAMSSGRGARLTRPRPGHADFAGMVKYNHDEARPILERSSARETAARVAAATVARSFL
RETLGVEVFSHVISIGRSEIDQTVCPTFEDLGRIDDSPVRSASAQAEASMIDQINAAKKQGDTLGGIVEVIVNGLPIGLG
SHISGEDRLDAQLAAALMGIQAIKGVEIGDGFEEARRLGSEAHDEIVLRDGVVARQSNRAGGIEGGMTNGESLRVRAAMK
PISTVPRALQSIDMDSGKRATGIHQRSDVCAVPAAGVVAEAMVALVLARAVLEKFGGDSLAETKRNIAAYNEYVKTRIAF
DGE

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; seventh step. [C]

COG id: COG0082

COG function: function code E; Chorismate synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the chorismate synthase family

Homologues:

Organism=Escherichia coli, GI1788669, Length=374, Percent_Identity=35.2941176470588, Blast_Score=177, Evalue=1e-45,
Organism=Saccharomyces cerevisiae, GI6321290, Length=382, Percent_Identity=31.9371727748691, Blast_Score=176, Evalue=5e-45,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): AROC_CORDI (Q6NH02)

Other databases:

- EMBL:   BX248357
- RefSeq:   NP_939698.1
- ProteinModelPortal:   Q6NH02
- SMR:   Q6NH02
- GeneID:   2648788
- GenomeReviews:   BX248353_GR
- KEGG:   cdi:DIP1345
- NMPDR:   fig|257309.1.peg.1289
- HOGENOM:   HBG292336
- OMA:   GSEAHDE
- ProtClustDB:   PRK05382
- BioCyc:   CDIP257309:DIP1345-MONOMER
- BRENDA:   4.2.3.5
- HAMAP:   MF_00300_B
- InterPro:   IPR000453
- InterPro:   IPR020541
- PANTHER:   PTHR21085
- PIRSF:   PIRSF001456
- TIGRFAMs:   TIGR00033

Pfam domain/function: PF01264 Chorismate_synt; SSF103263 Chorismate_synth

EC number: =4.2.3.5

Molecular weight: Translated: 42892; Mature: 42892

Theoretical pI: Translated: 6.07; Mature: 6.07

Prosite motif: PS00787 CHORISMATE_SYNTHASE_1; PS00788 CHORISMATE_SYNTHASE_2; PS00789 CHORISMATE_SYNTHASE_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLRWTTAGESHGQALIAMLEHMPAGVPISREEISFQLGRRRLGFGRGARMKFEADEVSIL
CCEECCCCCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCCCCEEECCCHHHHH
GGVRHGYTIGSPIAIMVGNTEWPKWTTIMSADAIDESDPDVAAAMSSGRGARLTRPRPGH
HCCCCCCCCCCCEEEEECCCCCCCEEEEEECCCCCCCCCHHHHHHHCCCCCCCCCCCCCC
ADFAGMVKYNHDEARPILERSSARETAARVAAATVARSFLRETLGVEVFSHVISIGRSEI
CCCHHHEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DQTVCPTFEDLGRIDDSPVRSASAQAEASMIDQINAAKKQGDTLGGIVEVIVNGLPIGLG
HHHHCCCHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCC
SHISGEDRLDAQLAAALMGIQAIKGVEIGDGFEEARRLGSEAHDEIVLRDGVVARQSNRA
CCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHCCCHHHCCEEEECCCCEECCCCC
GGIEGGMTNGESLRVRAAMKPISTVPRALQSIDMDSGKRATGIHQRSDVCAVPAAGVVAE
CCCCCCCCCCCCEEEHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCHHHHHH
AMVALVLARAVLEKFGGDSLAETKRNIAAYNEYVKTRIAFDGE
HHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHEECCCC
>Mature Secondary Structure
MLRWTTAGESHGQALIAMLEHMPAGVPISREEISFQLGRRRLGFGRGARMKFEADEVSIL
CCEECCCCCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCCCCEEECCCHHHHH
GGVRHGYTIGSPIAIMVGNTEWPKWTTIMSADAIDESDPDVAAAMSSGRGARLTRPRPGH
HCCCCCCCCCCCEEEEECCCCCCCEEEEEECCCCCCCCCHHHHHHHCCCCCCCCCCCCCC
ADFAGMVKYNHDEARPILERSSARETAARVAAATVARSFLRETLGVEVFSHVISIGRSEI
CCCHHHEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DQTVCPTFEDLGRIDDSPVRSASAQAEASMIDQINAAKKQGDTLGGIVEVIVNGLPIGLG
HHHHCCCHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCC
SHISGEDRLDAQLAAALMGIQAIKGVEIGDGFEEARRLGSEAHDEIVLRDGVVARQSNRA
CCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHCCCHHHCCEEEECCCCEECCCCC
GGIEGGMTNGESLRVRAAMKPISTVPRALQSIDMDSGKRATGIHQRSDVCAVPAAGVVAE
CCCCCCCCCCCCEEEHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCHHHHHH
AMVALVLARAVLEKFGGDSLAETKRNIAAYNEYVKTRIAFDGE
HHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHEECCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 14602910