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The map label for this gene is rho [H]

Identifier: 38233634

GI number: 38233634

Start: 1021371

End: 1023434

Strand: Direct

Name: rho [H]

Synonym: DIP1040

Alternate gene names: 38233634

Gene position: 1021371-1023434 (Clockwise)

Preceding gene: 38233632

Following gene: 38233635

Centisome position: 41.04

GC content: 53.59

Gene sequence:

>2064_bases
GTGACTAATACAGATAACAGCGCACAGCGTAATCTCGCTGCTCTGCGTTTGCCCGAACTGCGCAAAATTGCCGCAGAAAT
GGGCCTGAAAGGTACGTCCGCCCTGCGTAAGGGTGATCTAATCGCGGCTATTAACGGTACCTCTGCCGCTCATCCAACAT
CTGTGGCCCCCTCGGAAGAGAACAAAGCAGATGCACCAAAGAAGGAACGTCCAGCACGTCGTCGTGCGACTAAGCACGTT
GCCCAAGATGCCGGTTCCGAGCCAGCGCCAGTGGTAACAGAAGTTGCTGCGCCTGCAGAACAGAATCCTGCGCCAAAACA
AGAAAAAGAAGCTCCAGCTGGTGAGTCCGAGCGTCAGCCACGCCGTCGTCGTGCAGTAAAGACGTCTGTGAAAACAACGC
AGGAGGAACCCACTGAGGTTCGCGTAGCAGAAGCTGCAGAAGCTACTGACAAATCTTCCGAAGAGCAGTCCGCTGAGGCA
GGTTCTGAGGATAAAGATAACTACCACTACGAGTCTCGTTCTGCCGCTCGACGTGCCCGGCGTAACCGTGCTCGTCGTGA
GCAGCGCGAATACAATCGCCCTGGCACTAAAGATGAGAGCGAAGCATCTCAGCCAGAAAATGAGAACTCTCGCAACGACG
TCGCACCAGAATCCTCTAAGGTAGCAGACAACAGCAACGAGCAAGCTCGTTCTGATCAAGCTGATCAACCCACCAAGTCG
GACTCTAACGACAATGGTCGTGAGGATAACCGTCGTGGCAATCGACACGAGCGTGGGGAGCGTGGCGATCGTGGGGACCG
CAACCGTCGTAATCGTCGTAATCGTCGTGGCCGTGACCGTGATGATAACCGTGATAATCGCGAAAATAACAACAACGAAC
CACGTGAAGATGAAGTCTTGCAAAATGTTGCAGGCATCTTGGACATCGTGGACAACAATGTTGCTTTCGTGCGTACCTCT
GGTTACCACGCCGGTGCTGCTGACGTCTATGTGAACAACCAGATGATTCGCCGCTTGGGATTGCGTTCTGGCGACGCAAT
TGTGGGCCAAGTTCGTATGAATGGCGAAAACAATCACGGCGGACACAACCGTGGCCGTAACCGCCAGAAGTACAACCCAT
TGGTACGCGTTGATTCAGTCAACGGAATGACGGTGGAAGAAGCAAAGGCACGCCCTGAGTTTGCCAAGCTCACCCCGTTG
TACCCCAACCAGCGTCTGCGCCTCGAAACCGAGCCTAAGGTTTTGACTACCCGTGTGATCGATTTGATCATGCCGATTGG
TAAAGGTCAGCGTGCTTTGATCGTGTCTCCTCCTAAGGCTGGTAAGACCACGATCCTGCAAAATATCGCAAACGCTATTG
CTACCAACAACCCAGAGTGCTACCTCATGGTTGTTTTGGTGGATGAGCGTCCGGAAGAAGTTACCGATATGCAGCGTTCT
GTGAAGGGCGAAGTTATTGCATCGACCTTCGACCGTCCACCAAGTGAGCACACTGCTGTTGCAGAGCTCGCTATTGAGCG
TGCGAAGCGCCTTGTGGAGCAGGGACAGGATGTTGTAGTACTCCTAGACTCCATTACGCGTCTTGGCCGTGCCTACAATA
ACAGCTCACCTGCATCCGGCCGAATTCTCTCCGGTGGTGTGGACTCTAACGCGTTGTACCCACCAAAGCGTTTCCTTGGT
GCGGCTCGCAACATCGAAAATGGTGGATCGCTTACGATTATCGCCACGGCCATGGTTGAGACTGGTTCTGCCGGCGACAC
CGTGATCTTCGAGGAATTCAAGGGCACCGGTAACGCCGAGCTGAAGCTGGATCGTAAGATTTCTGAGCGCCGTGTATTCC
CAGCTGTCGACGTCAACCCATCGGGTACTCGTAAGGATGAGTTGCTGCTGGCTCCGGAAGAAGCTCGCATTATGCACAAA
CTCCGCCGCATGCTTTCTGCTTTGGATAATCAGCAGGCTATCGATTTGTTGATCAAGCAGCTCAAGAAGACCAAGTCCAA
TGGTGAATTCTTGATGCAGGTAGCAAGTTCTGCGCCGATGGCTGCGGATGCTGAGGAGGACTAA

Upstream 100 bases:

>100_bases
TGAATCCAGTCAATTCCACAGAATGCTGTCAGCGGTTGTGTCTTGGTTGAACTATTCCCAGTGACTCCTTGACTGCTGAT
CACGCAATGAAAGGACATCT

Downstream 100 bases:

>100_bases
TGTCTCAGGTTTCTGCAGTTGACGACATCGTCTCGGAATACCAAGGCATTGAAGCCCAAATGTCTGATCCAGAGACGATG
GGTGACCAAACGCTATTCCG

Product: transcription termination factor Rho

Products: NA

Alternate protein names: ATP-dependent helicase Rho [H]

Number of amino acids: Translated: 687; Mature: 686

Protein sequence:

>687_residues
MTNTDNSAQRNLAALRLPELRKIAAEMGLKGTSALRKGDLIAAINGTSAAHPTSVAPSEENKADAPKKERPARRRATKHV
AQDAGSEPAPVVTEVAAPAEQNPAPKQEKEAPAGESERQPRRRRAVKTSVKTTQEEPTEVRVAEAAEATDKSSEEQSAEA
GSEDKDNYHYESRSAARRARRNRARREQREYNRPGTKDESEASQPENENSRNDVAPESSKVADNSNEQARSDQADQPTKS
DSNDNGREDNRRGNRHERGERGDRGDRNRRNRRNRRGRDRDDNRDNRENNNNEPREDEVLQNVAGILDIVDNNVAFVRTS
GYHAGAADVYVNNQMIRRLGLRSGDAIVGQVRMNGENNHGGHNRGRNRQKYNPLVRVDSVNGMTVEEAKARPEFAKLTPL
YPNQRLRLETEPKVLTTRVIDLIMPIGKGQRALIVSPPKAGKTTILQNIANAIATNNPECYLMVVLVDERPEEVTDMQRS
VKGEVIASTFDRPPSEHTAVAELAIERAKRLVEQGQDVVVLLDSITRLGRAYNNSSPASGRILSGGVDSNALYPPKRFLG
AARNIENGGSLTIIATAMVETGSAGDTVIFEEFKGTGNAELKLDRKISERRVFPAVDVNPSGTRKDELLLAPEEARIMHK
LRRMLSALDNQQAIDLLIKQLKKTKSNGEFLMQVASSAPMAADAEED

Sequences:

>Translated_687_residues
MTNTDNSAQRNLAALRLPELRKIAAEMGLKGTSALRKGDLIAAINGTSAAHPTSVAPSEENKADAPKKERPARRRATKHV
AQDAGSEPAPVVTEVAAPAEQNPAPKQEKEAPAGESERQPRRRRAVKTSVKTTQEEPTEVRVAEAAEATDKSSEEQSAEA
GSEDKDNYHYESRSAARRARRNRARREQREYNRPGTKDESEASQPENENSRNDVAPESSKVADNSNEQARSDQADQPTKS
DSNDNGREDNRRGNRHERGERGDRGDRNRRNRRNRRGRDRDDNRDNRENNNNEPREDEVLQNVAGILDIVDNNVAFVRTS
GYHAGAADVYVNNQMIRRLGLRSGDAIVGQVRMNGENNHGGHNRGRNRQKYNPLVRVDSVNGMTVEEAKARPEFAKLTPL
YPNQRLRLETEPKVLTTRVIDLIMPIGKGQRALIVSPPKAGKTTILQNIANAIATNNPECYLMVVLVDERPEEVTDMQRS
VKGEVIASTFDRPPSEHTAVAELAIERAKRLVEQGQDVVVLLDSITRLGRAYNNSSPASGRILSGGVDSNALYPPKRFLG
AARNIENGGSLTIIATAMVETGSAGDTVIFEEFKGTGNAELKLDRKISERRVFPAVDVNPSGTRKDELLLAPEEARIMHK
LRRMLSALDNQQAIDLLIKQLKKTKSNGEFLMQVASSAPMAADAEED
>Mature_686_residues
TNTDNSAQRNLAALRLPELRKIAAEMGLKGTSALRKGDLIAAINGTSAAHPTSVAPSEENKADAPKKERPARRRATKHVA
QDAGSEPAPVVTEVAAPAEQNPAPKQEKEAPAGESERQPRRRRAVKTSVKTTQEEPTEVRVAEAAEATDKSSEEQSAEAG
SEDKDNYHYESRSAARRARRNRARREQREYNRPGTKDESEASQPENENSRNDVAPESSKVADNSNEQARSDQADQPTKSD
SNDNGREDNRRGNRHERGERGDRGDRNRRNRRNRRGRDRDDNRDNRENNNNEPREDEVLQNVAGILDIVDNNVAFVRTSG
YHAGAADVYVNNQMIRRLGLRSGDAIVGQVRMNGENNHGGHNRGRNRQKYNPLVRVDSVNGMTVEEAKARPEFAKLTPLY
PNQRLRLETEPKVLTTRVIDLIMPIGKGQRALIVSPPKAGKTTILQNIANAIATNNPECYLMVVLVDERPEEVTDMQRSV
KGEVIASTFDRPPSEHTAVAELAIERAKRLVEQGQDVVVLLDSITRLGRAYNNSSPASGRILSGGVDSNALYPPKRFLGA
ARNIENGGSLTIIATAMVETGSAGDTVIFEEFKGTGNAELKLDRKISERRVFPAVDVNPSGTRKDELLLAPEEARIMHKL
RRMLSALDNQQAIDLLIKQLKKTKSNGEFLMQVASSAPMAADAEED

Specific function: Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template [H]

COG id: COG1158

COG function: function code K; Transcription termination factor

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Rho family [H]

Homologues:

Organism=Escherichia coli, GI1790217, Length=374, Percent_Identity=55.6149732620321, Blast_Score=407, Evalue=1e-114,

Paralogues:

None

Copy number: 300 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000194
- InterPro:   IPR003593
- InterPro:   IPR011129
- InterPro:   IPR012340
- InterPro:   IPR011112
- InterPro:   IPR011113
- InterPro:   IPR004665 [H]

Pfam domain/function: PF00006 ATP-synt_ab; PF07498 Rho_N; PF07497 Rho_RNA_bind [H]

EC number: NA

Molecular weight: Translated: 75832; Mature: 75701

Theoretical pI: Translated: 9.43; Mature: 9.43

Prosite motif: PS00138 SUBTILASE_SER

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.1 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.1 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTNTDNSAQRNLAALRLPELRKIAAEMGLKGTSALRKGDLIAAINGTSAAHPTSVAPSEE
CCCCCCHHHHHHHHHCCHHHHHHHHHHCCCHHHHHHCCCEEEEECCCCCCCCCCCCCCCC
NKADAPKKERPARRRATKHVAQDAGSEPAPVVTEVAAPAEQNPAPKQEKEAPAGESERQP
CCCCCCHHHCHHHHHHHHHHHHHCCCCCCCHHHHHCCCCCCCCCCCHHHCCCCCCCCCCH
RRRRAVKTSVKTTQEEPTEVRVAEAAEATDKSSEEQSAEAGSEDKDNYHYESRSAARRAR
HHHHHHHHHHHHCCCCCCCEEHHHHHHHHCCCCHHHHHHCCCCCCCCCCHHHHHHHHHHH
RNRARREQREYNRPGTKDESEASQPENENSRNDVAPESSKVADNSNEQARSDQADQPTKS
HHHHHHHHHHHCCCCCCCCHHHCCCCCCCCCCCCCCCCCCCCCCCCHHHHCCCCCCCCCC
DSNDNGREDNRRGNRHERGERGDRGDRNRRNRRNRRGRDRDDNRDNRENNNNEPREDEVL
CCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHH
QNVAGILDIVDNNVAFVRTSGYHAGAADVYVNNQMIRRLGLRSGDAIVGQVRMNGENNHG
HHHHHHHHHHCCCEEEEEECCCCCCCEEEEECHHHHHHHCCCCCCEEEEEEEECCCCCCC
GHNRGRNRQKYNPLVRVDSVNGMTVEEAKARPEFAKLTPLYPNQRLRLETEPKVLTTRVI
CCCCCCCCCCCCCEEEEECCCCCCHHHHHCCCCHHHCCCCCCCCCEEECCCCHHHHHHHH
DLIMPIGKGQRALIVSPPKAGKTTILQNIANAIATNNPECYLMVVLVDERPEEVTDMQRS
HHHHCCCCCCEEEEECCCCCCHHHHHHHHHHHHHCCCCCEEEEEEEECCCCHHHHHHHHH
VKGEVIASTFDRPPSEHTAVAELAIERAKRLVEQGQDVVVLLDSITRLGRAYNNSSPASG
HCCHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHCCCCCCCC
RILSGGVDSNALYPPKRFLGAARNIENGGSLTIIATAMVETGSAGDTVIFEEFKGTGNAE
CEEECCCCCCCCCCCHHHHHHHHCCCCCCCEEEEEEEEECCCCCCCEEEEECCCCCCCCE
LKLDRKISERRVFPAVDVNPSGTRKDELLLAPEEARIMHKLRRMLSALDNQQAIDLLIKQ
EEECCHHHHCCCCCEECCCCCCCCCCCEEECCHHHHHHHHHHHHHHHHCCHHHHHHHHHH
LKKTKSNGEFLMQVASSAPMAADAEED
HHHCCCCCHHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure 
TNTDNSAQRNLAALRLPELRKIAAEMGLKGTSALRKGDLIAAINGTSAAHPTSVAPSEE
CCCCCHHHHHHHHHCCHHHHHHHHHHCCCHHHHHHCCCEEEEECCCCCCCCCCCCCCCC
NKADAPKKERPARRRATKHVAQDAGSEPAPVVTEVAAPAEQNPAPKQEKEAPAGESERQP
CCCCCCHHHCHHHHHHHHHHHHHCCCCCCCHHHHHCCCCCCCCCCCHHHCCCCCCCCCCH
RRRRAVKTSVKTTQEEPTEVRVAEAAEATDKSSEEQSAEAGSEDKDNYHYESRSAARRAR
HHHHHHHHHHHHCCCCCCCEEHHHHHHHHCCCCHHHHHHCCCCCCCCCCHHHHHHHHHHH
RNRARREQREYNRPGTKDESEASQPENENSRNDVAPESSKVADNSNEQARSDQADQPTKS
HHHHHHHHHHHCCCCCCCCHHHCCCCCCCCCCCCCCCCCCCCCCCCHHHHCCCCCCCCCC
DSNDNGREDNRRGNRHERGERGDRGDRNRRNRRNRRGRDRDDNRDNRENNNNEPREDEVL
CCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHH
QNVAGILDIVDNNVAFVRTSGYHAGAADVYVNNQMIRRLGLRSGDAIVGQVRMNGENNHG
HHHHHHHHHHCCCEEEEEECCCCCCCEEEEECHHHHHHHCCCCCCEEEEEEEECCCCCCC
GHNRGRNRQKYNPLVRVDSVNGMTVEEAKARPEFAKLTPLYPNQRLRLETEPKVLTTRVI
CCCCCCCCCCCCCEEEEECCCCCCHHHHHCCCCHHHCCCCCCCCCEEECCCCHHHHHHHH
DLIMPIGKGQRALIVSPPKAGKTTILQNIANAIATNNPECYLMVVLVDERPEEVTDMQRS
HHHHCCCCCCEEEEECCCCCCHHHHHHHHHHHHHCCCCCEEEEEEEECCCCHHHHHHHHH
VKGEVIASTFDRPPSEHTAVAELAIERAKRLVEQGQDVVVLLDSITRLGRAYNNSSPASG
HCCHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHCCCCCCCC
RILSGGVDSNALYPPKRFLGAARNIENGGSLTIIATAMVETGSAGDTVIFEEFKGTGNAE
CEEECCCCCCCCCCCHHHHHHHHCCCCCCCEEEEEEEEECCCCCCCEEEEECCCCCCCCE
LKLDRKISERRVFPAVDVNPSGTRKDELLLAPEEARIMHKLRRMLSALDNQQAIDLLIKQ
EEECCHHHHCCCCCEECCCCCCCCCCCEEECCHHHHHHHHHHHHHHHHCCHHHHHHHHHH
LKKTKSNGEFLMQVASSAPMAADAEED
HHHCCCCCHHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11234002 [H]