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The map label for this gene is typA [H]

Identifier: 38233564

GI number: 38233564

Start: 939899

End: 941809

Strand: Direct

Name: typA [H]

Synonym: DIP0969

Alternate gene names: 38233564

Gene position: 939899-941809 (Clockwise)

Preceding gene: 38233559

Following gene: 38233565

Centisome position: 37.77

GC content: 57.09

Gene sequence:

>1911_bases
TTGACACGTCCAGAGTTTCGTAACGTCGCTATCGTCGCGCACGTTGACCATGGAAAGACCACGCTAGTCGACGCTATGCT
GCGCCAGTCCGGAGCCTTCGATGAGCATGCTGAGCTTGTTGACCGCGTGATGGACTCTGGTGACCTTGAAAAAGAAAAAG
GCATCACCATCCTCGCAAAGAACACCGCTGTGCGTCGCCGCGGTGCTGGCAAAGATGGCAATGACGTTGTTATTAACGTT
ATTGACACCCCAGGCCACGCTGACTTCGGTGGCGAGGTAGAACGCGCGCTGTCCATGGTGGACGGCGTTGTTTTGCTTGT
TGACGCCTCCGAAGGCCCACTGCCACAGACCCGCTTCGTGCTTGGCAAGGCTTTGGCCGCGAAGATGCCAGTCGTAATTT
TGGTGAACAAGACCGATCGTCCAGACGCTCGTATCGACGAGGTTGTCGAAGAGTCTCAGGATCTCCTCCTAGAGTTGGCA
TCGGCACTCGATGATCCAGAGGCTGCCGAAGCTGCAGAACAGCTGCTCGACCTGCCAGTTCTTTACGCTTCCGGCCGTGA
GGGCAAGGCAAGCACCGTTAACCCTGGCAACGGAAACGTTCCAGACGCTGAGGATCTGCAGGCATTGTTCGACGTGATCT
ACGAGGTCATGCCAGAGCCAACCGTGAACGTCGATGGCCCACTGCAGGCACACGTGACCAACTTGGACTCCTCTTCCTTC
TTGGGTCGTATCGGCCTGATCCGTGTGCACTCCGGTTCTTTGAAGAAGGGCCAGCAAGTTGCGTGGATTCACTACGACGA
AGAAGGCAACCAGCACACCAAGACCGCTAAGATCGCAGAATTGCTGCGCACCGTTGGCGTGACCCGTGTTCCTGCAGACG
AGGTTGTTGCAGGCGACATTGCTGCTATCTCCGGTATCGACTCCATCATGATCGGTGACACCCTCGCTGATCTTGAGCAC
CCAGTGGCTCTGCCTCGTATCACCGTTGATGAGCCAGCGATCTCCATGACCATCGGTGTGAACACCTCGCCACTTGCTGG
CCGTGGTGGCGGCGACAAGCTCACCGCACGTGTGGTCAAGGCACGCCTTGAGCAGGAACTCATCGGTAACGTTTCTCTGC
GCGTTTTGCCTACTGAGCGTCCAGACGCTTGGGAGGTTCAGGGCCGCGGCGAAATGGCTCTGTCCGTTCTCGTTGAAACC
ATGCGTCGCGAAGGCTTCGAGTTGACTGTGGGCAAGCCACAGGTTGTTACTCAGACTGTCGATGGCAAGCTCTTCGAGCC
ATACGAGCACATGGTCATCGACATTCCTTCCGAGTACCAAGGCAACGTCACCCAGCTCATGGCCGCTAGGAAGGGCCAGA
TGCTGTCCATGGACAACATCTCCGATGAGTGGGTTCGCATGGAATACAAGGTTCCAGCCCGTGGCCTGATCTCTTTCCGC
ACCATGTTCATGACCGAAACCCGTGGTACCGGTATCGCAAACTCCTACTCCGAAGGCCTTGACGAGTGGGCTGGCGAAAT
CAAGGGCCGTGCTACCGGTTCGCTCGTGGCTGACCGCTCCGGTCAGATCACTGCCTACGCACTTCAGCAGCTTGCCGACC
GCGGTAACTTCTTCGTCGAGCCAGGCACCGAAGCCTACGAGGGCATGGTTGTTGGTGCCAACAACCGTGACGAGGACATG
GATGTTAACATCACCCGTGAAAAGAAGCTGACCAACATGCGTTCCGCAACAGCAGACGCAACCGTCACCTTGGCAAAAGC
TCGTAGCCTCTCCTTGGATGAAGCGATGGAGTTCTGTGGCCAAGACGAGTGCGTTGAGGTCACCCCTGACGTGCTGCGCG
TACGCAAGGTCATCCTAAATGCAACCGAGCGTGGTCGCGCGCGTGCACGCGAAAAGGCTCGTAACAAGTAA

Upstream 100 bases:

>100_bases
GCTCATTTCGACGTACTTCCGTGATGGCGGTTGCCAGGCGTTCGTCGAAAAGCGGCCACTGAGGCATGAGAGTGCATATT
TAATTTTTCAGGAGATTTCT

Downstream 100 bases:

>100_bases
GATAGGTTCCATGTCAAACAAGCACCGTATCCTCGTTCCACTACTGGCTACGGCGCTTGTGTCATGTTCAGCCAATCCAG
GACCTGCACCCGTGGAGAAG

Product: putative GTP-binding elongation factor

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 636; Mature: 635

Protein sequence:

>636_residues
MTRPEFRNVAIVAHVDHGKTTLVDAMLRQSGAFDEHAELVDRVMDSGDLEKEKGITILAKNTAVRRRGAGKDGNDVVINV
IDTPGHADFGGEVERALSMVDGVVLLVDASEGPLPQTRFVLGKALAAKMPVVILVNKTDRPDARIDEVVEESQDLLLELA
SALDDPEAAEAAEQLLDLPVLYASGREGKASTVNPGNGNVPDAEDLQALFDVIYEVMPEPTVNVDGPLQAHVTNLDSSSF
LGRIGLIRVHSGSLKKGQQVAWIHYDEEGNQHTKTAKIAELLRTVGVTRVPADEVVAGDIAAISGIDSIMIGDTLADLEH
PVALPRITVDEPAISMTIGVNTSPLAGRGGGDKLTARVVKARLEQELIGNVSLRVLPTERPDAWEVQGRGEMALSVLVET
MRREGFELTVGKPQVVTQTVDGKLFEPYEHMVIDIPSEYQGNVTQLMAARKGQMLSMDNISDEWVRMEYKVPARGLISFR
TMFMTETRGTGIANSYSEGLDEWAGEIKGRATGSLVADRSGQITAYALQQLADRGNFFVEPGTEAYEGMVVGANNRDEDM
DVNITREKKLTNMRSATADATVTLAKARSLSLDEAMEFCGQDECVEVTPDVLRVRKVILNATERGRARAREKARNK

Sequences:

>Translated_636_residues
MTRPEFRNVAIVAHVDHGKTTLVDAMLRQSGAFDEHAELVDRVMDSGDLEKEKGITILAKNTAVRRRGAGKDGNDVVINV
IDTPGHADFGGEVERALSMVDGVVLLVDASEGPLPQTRFVLGKALAAKMPVVILVNKTDRPDARIDEVVEESQDLLLELA
SALDDPEAAEAAEQLLDLPVLYASGREGKASTVNPGNGNVPDAEDLQALFDVIYEVMPEPTVNVDGPLQAHVTNLDSSSF
LGRIGLIRVHSGSLKKGQQVAWIHYDEEGNQHTKTAKIAELLRTVGVTRVPADEVVAGDIAAISGIDSIMIGDTLADLEH
PVALPRITVDEPAISMTIGVNTSPLAGRGGGDKLTARVVKARLEQELIGNVSLRVLPTERPDAWEVQGRGEMALSVLVET
MRREGFELTVGKPQVVTQTVDGKLFEPYEHMVIDIPSEYQGNVTQLMAARKGQMLSMDNISDEWVRMEYKVPARGLISFR
TMFMTETRGTGIANSYSEGLDEWAGEIKGRATGSLVADRSGQITAYALQQLADRGNFFVEPGTEAYEGMVVGANNRDEDM
DVNITREKKLTNMRSATADATVTLAKARSLSLDEAMEFCGQDECVEVTPDVLRVRKVILNATERGRARAREKARNK
>Mature_635_residues
TRPEFRNVAIVAHVDHGKTTLVDAMLRQSGAFDEHAELVDRVMDSGDLEKEKGITILAKNTAVRRRGAGKDGNDVVINVI
DTPGHADFGGEVERALSMVDGVVLLVDASEGPLPQTRFVLGKALAAKMPVVILVNKTDRPDARIDEVVEESQDLLLELAS
ALDDPEAAEAAEQLLDLPVLYASGREGKASTVNPGNGNVPDAEDLQALFDVIYEVMPEPTVNVDGPLQAHVTNLDSSSFL
GRIGLIRVHSGSLKKGQQVAWIHYDEEGNQHTKTAKIAELLRTVGVTRVPADEVVAGDIAAISGIDSIMIGDTLADLEHP
VALPRITVDEPAISMTIGVNTSPLAGRGGGDKLTARVVKARLEQELIGNVSLRVLPTERPDAWEVQGRGEMALSVLVETM
RREGFELTVGKPQVVTQTVDGKLFEPYEHMVIDIPSEYQGNVTQLMAARKGQMLSMDNISDEWVRMEYKVPARGLISFRT
MFMTETRGTGIANSYSEGLDEWAGEIKGRATGSLVADRSGQITAYALQQLADRGNFFVEPGTEAYEGMVVGANNRDEDMD
VNITREKKLTNMRSATADATVTLAKARSLSLDEAMEFCGQDECVEVTPDVLRVRKVILNATERGRARAREKARNK

Specific function: Not known; probably interacts with the ribosomes in a GTP dependent manner [H]

COG id: COG1217

COG function: function code T; Predicted membrane GTPase involved in stress response

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GTP-binding elongation factor family. TypA subfamily [H]

Homologues:

Organism=Homo sapiens, GI157426893, Length=512, Percent_Identity=27.734375, Blast_Score=139, Evalue=1e-32,
Organism=Homo sapiens, GI94966754, Length=135, Percent_Identity=42.2222222222222, Blast_Score=106, Evalue=8e-23,
Organism=Homo sapiens, GI4503483, Length=145, Percent_Identity=37.9310344827586, Blast_Score=95, Evalue=2e-19,
Organism=Homo sapiens, GI18390331, Length=141, Percent_Identity=41.1347517730496, Blast_Score=95, Evalue=2e-19,
Organism=Homo sapiens, GI310132016, Length=115, Percent_Identity=41.7391304347826, Blast_Score=89, Evalue=1e-17,
Organism=Homo sapiens, GI310110807, Length=115, Percent_Identity=41.7391304347826, Blast_Score=89, Evalue=1e-17,
Organism=Homo sapiens, GI310123363, Length=115, Percent_Identity=41.7391304347826, Blast_Score=89, Evalue=1e-17,
Organism=Homo sapiens, GI217272892, Length=140, Percent_Identity=35, Blast_Score=87, Evalue=5e-17,
Organism=Homo sapiens, GI217272894, Length=140, Percent_Identity=35, Blast_Score=87, Evalue=6e-17,
Organism=Homo sapiens, GI25306283, Length=163, Percent_Identity=34.9693251533742, Blast_Score=82, Evalue=2e-15,
Organism=Homo sapiens, GI19923640, Length=163, Percent_Identity=34.9693251533742, Blast_Score=82, Evalue=2e-15,
Organism=Homo sapiens, GI25306287, Length=163, Percent_Identity=34.9693251533742, Blast_Score=81, Evalue=2e-15,
Organism=Homo sapiens, GI34147630, Length=273, Percent_Identity=28.2051282051282, Blast_Score=74, Evalue=4e-13,
Organism=Homo sapiens, GI94966752, Length=88, Percent_Identity=43.1818181818182, Blast_Score=69, Evalue=2e-11,
Organism=Escherichia coli, GI48994988, Length=624, Percent_Identity=46.474358974359, Blast_Score=542, Evalue=1e-155,
Organism=Escherichia coli, GI1789738, Length=533, Percent_Identity=26.8292682926829, Blast_Score=146, Evalue=5e-36,
Organism=Escherichia coli, GI1788922, Length=516, Percent_Identity=26.937984496124, Blast_Score=122, Evalue=1e-28,
Organism=Escherichia coli, GI1789737, Length=273, Percent_Identity=27.1062271062271, Blast_Score=72, Evalue=7e-14,
Organism=Escherichia coli, GI1790412, Length=273, Percent_Identity=27.1062271062271, Blast_Score=72, Evalue=7e-14,
Organism=Escherichia coli, GI1790835, Length=160, Percent_Identity=30.625, Blast_Score=70, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI17557151, Length=518, Percent_Identity=26.0617760617761, Blast_Score=128, Evalue=8e-30,
Organism=Caenorhabditis elegans, GI17556745, Length=349, Percent_Identity=27.5071633237822, Blast_Score=102, Evalue=7e-22,
Organism=Caenorhabditis elegans, GI17533571, Length=143, Percent_Identity=41.958041958042, Blast_Score=96, Evalue=7e-20,
Organism=Caenorhabditis elegans, GI71988811, Length=141, Percent_Identity=35.4609929078014, Blast_Score=92, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI71988819, Length=141, Percent_Identity=35.4609929078014, Blast_Score=91, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI17552882, Length=196, Percent_Identity=31.6326530612245, Blast_Score=89, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI17506493, Length=157, Percent_Identity=35.031847133758, Blast_Score=89, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI17556456, Length=283, Percent_Identity=30.0353356890459, Blast_Score=74, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI25141371, Length=264, Percent_Identity=27.2727272727273, Blast_Score=67, Evalue=3e-11,
Organism=Saccharomyces cerevisiae, GI6323320, Length=507, Percent_Identity=24.8520710059172, Blast_Score=117, Evalue=6e-27,
Organism=Saccharomyces cerevisiae, GI6324707, Length=145, Percent_Identity=40, Blast_Score=103, Evalue=1e-22,
Organism=Saccharomyces cerevisiae, GI6320593, Length=145, Percent_Identity=40, Blast_Score=103, Evalue=1e-22,
Organism=Saccharomyces cerevisiae, GI6323098, Length=230, Percent_Identity=33.9130434782609, Blast_Score=98, Evalue=3e-21,
Organism=Saccharomyces cerevisiae, GI6322359, Length=148, Percent_Identity=36.4864864864865, Blast_Score=85, Evalue=3e-17,
Organism=Saccharomyces cerevisiae, GI6324166, Length=141, Percent_Identity=38.2978723404255, Blast_Score=82, Evalue=3e-16,
Organism=Saccharomyces cerevisiae, GI6324761, Length=306, Percent_Identity=26.1437908496732, Blast_Score=81, Evalue=4e-16,
Organism=Drosophila melanogaster, GI78706572, Length=519, Percent_Identity=27.1676300578035, Blast_Score=135, Evalue=9e-32,
Organism=Drosophila melanogaster, GI21357743, Length=140, Percent_Identity=38.5714285714286, Blast_Score=97, Evalue=3e-20,
Organism=Drosophila melanogaster, GI28574573, Length=140, Percent_Identity=39.2857142857143, Blast_Score=96, Evalue=6e-20,
Organism=Drosophila melanogaster, GI24582462, Length=191, Percent_Identity=35.6020942408377, Blast_Score=94, Evalue=3e-19,
Organism=Drosophila melanogaster, GI24585709, Length=149, Percent_Identity=34.8993288590604, Blast_Score=89, Evalue=1e-17,
Organism=Drosophila melanogaster, GI24585711, Length=149, Percent_Identity=34.8993288590604, Blast_Score=89, Evalue=1e-17,
Organism=Drosophila melanogaster, GI24585713, Length=149, Percent_Identity=34.8993288590604, Blast_Score=89, Evalue=1e-17,
Organism=Drosophila melanogaster, GI221458488, Length=154, Percent_Identity=40.2597402597403, Blast_Score=88, Evalue=2e-17,
Organism=Drosophila melanogaster, GI281363316, Length=283, Percent_Identity=27.5618374558304, Blast_Score=83, Evalue=7e-16,
Organism=Drosophila melanogaster, GI17864358, Length=283, Percent_Identity=27.5618374558304, Blast_Score=83, Evalue=7e-16,
Organism=Drosophila melanogaster, GI19921738, Length=273, Percent_Identity=27.1062271062271, Blast_Score=73, Evalue=7e-13,
Organism=Drosophila melanogaster, GI28572034, Length=171, Percent_Identity=27.4853801169591, Blast_Score=69, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009022
- InterPro:   IPR000795
- InterPro:   IPR005225
- InterPro:   IPR000640
- InterPro:   IPR004161
- InterPro:   IPR009000
- InterPro:   IPR006298 [H]

Pfam domain/function: PF00679 EFG_C; PF00009 GTP_EFTU; PF03144 GTP_EFTU_D2 [H]

EC number: NA

Molecular weight: Translated: 69038; Mature: 68907

Theoretical pI: Translated: 4.61; Mature: 4.61

Prosite motif: PS00301 EFACTOR_GTP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTRPEFRNVAIVAHVDHGKTTLVDAMLRQSGAFDEHAELVDRVMDSGDLEKEKGITILAK
CCCCCCCCEEEEEEECCCCHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCCCEEEEEC
NTAVRRRGAGKDGNDVVINVIDTPGHADFGGEVERALSMVDGVVLLVDASEGPLPQTRFV
CCHHHHCCCCCCCCCEEEEEEECCCCCCCCHHHHHHHHHHCCEEEEEECCCCCCCHHHHH
LGKALAAKMPVVILVNKTDRPDARIDEVVEESQDLLLELASALDDPEAAEAAEQLLDLPV
HHHHHHHCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCE
LYASGREGKASTVNPGNGNVPDAEDLQALFDVIYEVMPEPTVNVDGPLQAHVTNLDSSSF
EEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEECCCCHHH
LGRIGLIRVHSGSLKKGQQVAWIHYDEEGNQHTKTAKIAELLRTVGVTRVPADEVVAGDI
HCCEEEEEEECCCCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHCCH
AAISGIDSIMIGDTLADLEHPVALPRITVDEPAISMTIGVNTSPLAGRGGGDKLTARVVK
HHHHCCCHHHCCCHHHHCCCCCCCCEEEECCCCEEEEECCCCCCCCCCCCCHHHHHHHHH
ARLEQELIGNVSLRVLPTERPDAWEVQGRGEMALSVLVETMRREGFELTVGKPQVVTQTV
HHHHHHHHCCCEEEEEECCCCCCEEECCCCHHHHHHHHHHHHHCCCEEECCCCEEEEEEC
DGKLFEPYEHMVIDIPSEYQGNVTQLMAARKGQMLSMDNISDEWVRMEYKVPARGLISFR
CCCEECCCCCEEEECCCHHCCCHHHHHHHHCCCEEECCCCCCCCEEEEEECCCCHHHHHH
TMFMTETRGTGIANSYSEGLDEWAGEIKGRATGSLVADRSGQITAYALQQLADRGNFFVE
HHHEEECCCCCCCCHHHHHHHHHHHHCCCCCCCCEEECCCCCCHHHHHHHHHHCCCEEEC
PGTEAYEGMVVGANNRDEDMDVNITREKKLTNMRSATADATVTLAKARSLSLDEAMEFCG
CCCHHHCCEEECCCCCCCCCEEEEEHHHHHHHHHHCCCCCEEEEEHHHCCCHHHHHHHHC
QDECVEVTPDVLRVRKVILNATERGRARAREKARNK
CCCCEECCHHHHHHHHHHHCCHHHHHHHHHHHHCCC
>Mature Secondary Structure 
TRPEFRNVAIVAHVDHGKTTLVDAMLRQSGAFDEHAELVDRVMDSGDLEKEKGITILAK
CCCCCCCEEEEEEECCCCHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCCCEEEEEC
NTAVRRRGAGKDGNDVVINVIDTPGHADFGGEVERALSMVDGVVLLVDASEGPLPQTRFV
CCHHHHCCCCCCCCCEEEEEEECCCCCCCCHHHHHHHHHHCCEEEEEECCCCCCCHHHHH
LGKALAAKMPVVILVNKTDRPDARIDEVVEESQDLLLELASALDDPEAAEAAEQLLDLPV
HHHHHHHCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCE
LYASGREGKASTVNPGNGNVPDAEDLQALFDVIYEVMPEPTVNVDGPLQAHVTNLDSSSF
EEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEECCCCHHH
LGRIGLIRVHSGSLKKGQQVAWIHYDEEGNQHTKTAKIAELLRTVGVTRVPADEVVAGDI
HCCEEEEEEECCCCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHCCH
AAISGIDSIMIGDTLADLEHPVALPRITVDEPAISMTIGVNTSPLAGRGGGDKLTARVVK
HHHHCCCHHHCCCHHHHCCCCCCCCEEEECCCCEEEEECCCCCCCCCCCCCHHHHHHHHH
ARLEQELIGNVSLRVLPTERPDAWEVQGRGEMALSVLVETMRREGFELTVGKPQVVTQTV
HHHHHHHHCCCEEEEEECCCCCCEEECCCCHHHHHHHHHHHHHCCCEEECCCCEEEEEEC
DGKLFEPYEHMVIDIPSEYQGNVTQLMAARKGQMLSMDNISDEWVRMEYKVPARGLISFR
CCCEECCCCCEEEECCCHHCCCHHHHHHHHCCCEEECCCCCCCCEEEEEECCCCHHHHHH
TMFMTETRGTGIANSYSEGLDEWAGEIKGRATGSLVADRSGQITAYALQQLADRGNFFVE
HHHEEECCCCCCCCHHHHHHHHHHHHCCCCCCCCEEECCCCCCHHHHHHHHHHCCCEEEC
PGTEAYEGMVVGANNRDEDMDVNITREKKLTNMRSATADATVTLAKARSLSLDEAMEFCG
CCCHHHCCEEECCCCCCCCCEEEEEHHHHHHHHHHCCCCCEEEEEHHHCCCHHHHHHHHC
QDECVEVTPDVLRVRKVILNATERGRARAREKARNK
CCCCEECCHHHHHHHHHHHCCHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]