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The map label for this gene is engD [H]

Identifier: 38233544

GI number: 38233544

Start: 919766

End: 920851

Strand: Direct

Name: engD [H]

Synonym: DIP0948

Alternate gene names: 38233544

Gene position: 919766-920851 (Clockwise)

Preceding gene: 38233539

Following gene: 38233546

Centisome position: 36.96

GC content: 53.5

Gene sequence:

>1086_bases
GTGAGCCTTACACTTGGAATCGTCGGCCTGCCCAATGTTGGCAAGTCCACGCTATTTAATGCCCTTACCCGCAACGACGT
TCTGGCGGCGAACTATCCCTTCGCAACCATCGAGCCCAACGTTGGTCTTGTCGAGCTTCCGGATGCTCGCCTGAACCGTC
TCGCAGAGATCTTCCAATCGGAGCGCATCTTGCCAGCTACGGTGTCCTTCGTTGACATTGCTGGCATTGTCAAAGGTGCA
TCCGAGGGTGAAGGCATGGGCAACGCCTTCCTAGCGAATATCCGCGAGGCTGACGCTATTTGCCAGGTAGTTCGTGCCTT
TGCTGACGACAACGTGATTCACGTTGATGGTCGAGTAGACCCAAGCTCAGACATCTCAGTGATCAACACCGAGCTCATCT
TGGCGGATCTACAAACAGTGGAAAAAGCGCTTCCTCGTCTTGAAAAAGAAGCCCGCAAGAACAAAGATCTGGCTGAAACC
GTCGAAGCAACCAAGAAAGCACAAGCCATTCTTGAAGACGACCGCACCTTATTCGCAGCATCCAAAAACGGTGAGATCGA
TCTCGCCCTAGTCCGCGAACTACACCTCATGACGGCTAAGCCATTCCTCTACGTCTTCAACTCCGATGAAGAAGTACTGA
CCGACGATGCCCGCAAGCAACAACTGCGTGACCTGGTAGCACCAGCAGAGGCAGTGTTCCTCGACGCAAAGACCGAGACT
GAGCTCCTCGAACTCGACGAGGATGAAGCCCTCGAATTGCTCGAGTCCGTCGGACAAACCGAACCTGGTCTTGCCACGCT
CGCAAAAGCCGGCTTTGCAACCTTGGGACTTCAGACTTACCTCACCGCAGGTCCTAAAGAATCGCGCGCATGGACGATCA
AGCAGGGATCTTTGGCGCCTCAAGCCGCTGGAGTTATCCACACCGACTTTGAAAAGAAATTCATCAAGGCCGAAATTGTC
TCCTTTGATGATCTCGATGCTGCTGGTTCCATTGCTGAAGCCAAGGCTCAGGGCAAGATGCGTATGGAAGGCAAAGACTA
CGTCATGCACGACGGCGATGTGTGTGACTTTAAGATCGGCGGCTAG

Upstream 100 bases:

>100_bases
ATGTTCACCGTTGCGACGCTTCCGTGATAGCTCCCCCTGATATACGTGCACAGCGCTGGTGGTGAGCCATTTTGCTGGCT
GCTTGCTAGGATGATCGTTC

Downstream 100 bases:

>100_bases
CTGCCAAAGCTATTAAAAACCGCGCCCCCTCCTAGAGACGAAGGGGCGCGGTTTTGCTGTGTTGAAGGGGATCCGGTTAG
TGCTTCTTTTTGTGGAAAGG

Product: GTP-dependent nucleic acid-binding protein EngD

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 361; Mature: 360

Protein sequence:

>361_residues
MSLTLGIVGLPNVGKSTLFNALTRNDVLAANYPFATIEPNVGLVELPDARLNRLAEIFQSERILPATVSFVDIAGIVKGA
SEGEGMGNAFLANIREADAICQVVRAFADDNVIHVDGRVDPSSDISVINTELILADLQTVEKALPRLEKEARKNKDLAET
VEATKKAQAILEDDRTLFAASKNGEIDLALVRELHLMTAKPFLYVFNSDEEVLTDDARKQQLRDLVAPAEAVFLDAKTET
ELLELDEDEALELLESVGQTEPGLATLAKAGFATLGLQTYLTAGPKESRAWTIKQGSLAPQAAGVIHTDFEKKFIKAEIV
SFDDLDAAGSIAEAKAQGKMRMEGKDYVMHDGDVCDFKIGG

Sequences:

>Translated_361_residues
MSLTLGIVGLPNVGKSTLFNALTRNDVLAANYPFATIEPNVGLVELPDARLNRLAEIFQSERILPATVSFVDIAGIVKGA
SEGEGMGNAFLANIREADAICQVVRAFADDNVIHVDGRVDPSSDISVINTELILADLQTVEKALPRLEKEARKNKDLAET
VEATKKAQAILEDDRTLFAASKNGEIDLALVRELHLMTAKPFLYVFNSDEEVLTDDARKQQLRDLVAPAEAVFLDAKTET
ELLELDEDEALELLESVGQTEPGLATLAKAGFATLGLQTYLTAGPKESRAWTIKQGSLAPQAAGVIHTDFEKKFIKAEIV
SFDDLDAAGSIAEAKAQGKMRMEGKDYVMHDGDVCDFKIGG
>Mature_360_residues
SLTLGIVGLPNVGKSTLFNALTRNDVLAANYPFATIEPNVGLVELPDARLNRLAEIFQSERILPATVSFVDIAGIVKGAS
EGEGMGNAFLANIREADAICQVVRAFADDNVIHVDGRVDPSSDISVINTELILADLQTVEKALPRLEKEARKNKDLAETV
EATKKAQAILEDDRTLFAASKNGEIDLALVRELHLMTAKPFLYVFNSDEEVLTDDARKQQLRDLVAPAEAVFLDAKTETE
LLELDEDEALELLESVGQTEPGLATLAKAGFATLGLQTYLTAGPKESRAWTIKQGSLAPQAAGVIHTDFEKKFIKAEIVS
FDDLDAAGSIAEAKAQGKMRMEGKDYVMHDGDVCDFKIGG

Specific function: GTP-dependent nucleic acid-binding protein which may act as a translation factor [H]

COG id: COG0012

COG function: function code J; Predicted GTPase, probable translation factor

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 G (guanine nucleotide-binding) domain [H]

Homologues:

Organism=Homo sapiens, GI58761500, Length=369, Percent_Identity=40.9214092140921, Blast_Score=266, Evalue=2e-71,
Organism=Homo sapiens, GI58761502, Length=172, Percent_Identity=41.2790697674419, Blast_Score=125, Evalue=9e-29,
Organism=Escherichia coli, GI1787454, Length=360, Percent_Identity=50.8333333333333, Blast_Score=351, Evalue=3e-98,
Organism=Escherichia coli, GI1789574, Length=234, Percent_Identity=29.9145299145299, Blast_Score=75, Evalue=8e-15,
Organism=Caenorhabditis elegans, GI17509631, Length=369, Percent_Identity=39.0243902439024, Blast_Score=252, Evalue=2e-67,
Organism=Saccharomyces cerevisiae, GI6319499, Length=373, Percent_Identity=38.8739946380697, Blast_Score=240, Evalue=3e-64,
Organism=Saccharomyces cerevisiae, GI6321773, Length=391, Percent_Identity=33.7595907928389, Blast_Score=209, Evalue=6e-55,
Organism=Drosophila melanogaster, GI24640873, Length=371, Percent_Identity=40.1617250673854, Blast_Score=261, Evalue=7e-70,
Organism=Drosophila melanogaster, GI24640877, Length=371, Percent_Identity=40.1617250673854, Blast_Score=261, Evalue=7e-70,
Organism=Drosophila melanogaster, GI24640875, Length=371, Percent_Identity=40.1617250673854, Blast_Score=261, Evalue=7e-70,
Organism=Drosophila melanogaster, GI24640879, Length=329, Percent_Identity=37.9939209726444, Blast_Score=209, Evalue=2e-54,
Organism=Drosophila melanogaster, GI24585318, Length=151, Percent_Identity=30.4635761589404, Blast_Score=68, Evalue=9e-12,

Paralogues:

None

Copy number: 120 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 140 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012675
- InterPro:   IPR004396
- InterPro:   IPR013029
- InterPro:   IPR006073
- InterPro:   IPR002917
- InterPro:   IPR012676
- InterPro:   IPR023192 [H]

Pfam domain/function: PF01926 MMR_HSR1; PF06071 YchF-GTPase_C [H]

EC number: NA

Molecular weight: Translated: 39030; Mature: 38898

Theoretical pI: Translated: 4.32; Mature: 4.32

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLTLGIVGLPNVGKSTLFNALTRNDVLAANYPFATIEPNVGLVELPDARLNRLAEIFQS
CCEEEEEEECCCCCHHHHHHHHHCCCEEEECCCCEEECCCCCEEECCHHHHHHHHHHHHC
ERILPATVSFVDIAGIVKGASEGEGMGNAFLANIREADAICQVVRAFADDNVIHVDGRVD
CCCCHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCC
PSSDISVINTELILADLQTVEKALPRLEKEARKNKDLAETVEATKKAQAILEDDRTLFAA
CCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCEEEEE
SKNGEIDLALVRELHLMTAKPFLYVFNSDEEVLTDDARKQQLRDLVAPAEAVFLDAKTET
CCCCCEEHHHHHHHHHHCCCCEEEEECCCCHHHHCHHHHHHHHHHHCCCHHEEEECCCCC
ELLELDEDEALELLESVGQTEPGLATLAKAGFATLGLQTYLTAGPKESRAWTIKQGSLAP
HHHHCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCC
QAAGVIHTDFEKKFIKAEIVSFDDLDAAGSIAEAKAQGKMRMEGKDYVMHDGDVCDFKIG
CCCCCEECCHHHHHHHHHHCCCCCCCCCCCHHHHHHCCCEEECCCCEEEECCCEEEEEEC
G
C
>Mature Secondary Structure 
SLTLGIVGLPNVGKSTLFNALTRNDVLAANYPFATIEPNVGLVELPDARLNRLAEIFQS
CEEEEEEECCCCCHHHHHHHHHCCCEEEECCCCEEECCCCCEEECCHHHHHHHHHHHHC
ERILPATVSFVDIAGIVKGASEGEGMGNAFLANIREADAICQVVRAFADDNVIHVDGRVD
CCCCHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCC
PSSDISVINTELILADLQTVEKALPRLEKEARKNKDLAETVEATKKAQAILEDDRTLFAA
CCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCEEEEE
SKNGEIDLALVRELHLMTAKPFLYVFNSDEEVLTDDARKQQLRDLVAPAEAVFLDAKTET
CCCCCEEHHHHHHHHHHCCCCEEEEECCCCHHHHCHHHHHHHHHHHCCCHHEEEECCCCC
ELLELDEDEALELLESVGQTEPGLATLAKAGFATLGLQTYLTAGPKESRAWTIKQGSLAP
HHHHCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCC
QAAGVIHTDFEKKFIKAEIVSFDDLDAAGSIAEAKAQGKMRMEGKDYVMHDGDVCDFKIG
CCCCCEECCHHHHHHHHHHCCCCCCCCCCCHHHHHHCCCEEECCCCEEEECCCEEEEEEC
G
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377 [H]