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The map label for this gene is glpX [H]

Identifier: 38233535

GI number: 38233535

Start: 910620

End: 911636

Strand: Reverse

Name: glpX [H]

Synonym: DIP0939

Alternate gene names: 38233535

Gene position: 911636-910620 (Counterclockwise)

Preceding gene: 38233537

Following gene: 38233534

Centisome position: 36.63

GC content: 57.42

Gene sequence:

>1017_bases
ATGACCAACCTCAACCCAGAGATTCCAGATCGCAACCTCGCCCTCGAGTTGGTTCGTGTTACCGAGGCAGCTGCACTGGC
GTCTGGCCGCTGGGTCGGTCGCGGCATGAAGAACGAGGGTGACGGAGCAGCTGTCGACGCCATGCGTAAGCTCATCAACT
CAGTTCAAATGAACGGCGTGGTTGTTATTGGAGAAGGCGAAAAAGACGAAGCCCCTATGCTCTTCAATGGCGAACAGGTA
GGCACCGGCGAAGGCGCAGCAGTTGACATTGCTGTTGATCCCGTCGATGGCACTACCTTGATGGCAGAAGGTCGCCCCAA
CGCTATTTCCGTCCTAGCCGCCGCCGAGCGTGGTTCCATGTACGACCCATCTGCCGTGTTCTACATGCGCAAGATCGCCG
TTGGACCAGAAGCAGCGGGCACCATCGACATCAACGCACCAGTCGAGTACAACATCAAGGCCGTAGCAAAGGCTAAGGGT
ATTGCCCCAGACCAGGTCACCGTTGTTGTCTTGGATCGCCCACGCCACGAAACCCTGATCAAAGACATTCGCGAGGCCGG
CGCTAAGGTGCGCCTGATTCGCGATGGCGACGTTGCAGGTGCAGTTGCTGCTGCTCAAGCAACCAACTCAGTCGACATCA
TGATGGGTACCGGTGGAACCCCAGAAGGTATCATCACCGCATGCGCTATGAAGTGCATGGGTGGCGAAATCCAAGGTGTG
CTGGCCCCCAAGGATGATGCGGAGGCCGCCAAGGCACGCAATGCTGGCCACGAGCTCAACCGCGTTCTGGGAACCCATGA
CCTCGTCTCTTCAGACAACTGCTTCTTCGTCGCTACCGGTGTGACTAATGGCGACATGCTCCGTGGCGTGAGCTACCGTG
CCGACGGCGCAACCACCCGCTCGCTCGTTATGCGTTCTAAGTCCGGCACTGTTCGTTTCATCGAATCCACCCACAAGCTG
CACAAACTGCAGGAATACTCTGTGGTTGATTACTCCCAGATTTCCCCACGGAAGTAG

Upstream 100 bases:

>100_bases
GAGGATCTCCCCCGTGTCCCCTCGCTATGCTGTTCGCGTCACCATATAAGCAGTTCCCACTATTGAGATTTTTAACGTCA
TCCACAGGAGGCATTCCCTT

Downstream 100 bases:

>100_bases
TGGCATCTAAAAAGTAATTTTTATCACCCACACCCCGTAACCTTTGTCCTAAGCACAGGTGAACGGGGTGTTTTTATTAG
CTTACGTAGCCCCGTTCTTA

Product: fructose 1,6-bisphosphatase II

Products: NA

Alternate protein names: FBPase class 2; D-fructose-1,6-bisphosphate 1-phosphohydrolase class 2 [H]

Number of amino acids: Translated: 338; Mature: 337

Protein sequence:

>338_residues
MTNLNPEIPDRNLALELVRVTEAAALASGRWVGRGMKNEGDGAAVDAMRKLINSVQMNGVVVIGEGEKDEAPMLFNGEQV
GTGEGAAVDIAVDPVDGTTLMAEGRPNAISVLAAAERGSMYDPSAVFYMRKIAVGPEAAGTIDINAPVEYNIKAVAKAKG
IAPDQVTVVVLDRPRHETLIKDIREAGAKVRLIRDGDVAGAVAAAQATNSVDIMMGTGGTPEGIITACAMKCMGGEIQGV
LAPKDDAEAAKARNAGHELNRVLGTHDLVSSDNCFFVATGVTNGDMLRGVSYRADGATTRSLVMRSKSGTVRFIESTHKL
HKLQEYSVVDYSQISPRK

Sequences:

>Translated_338_residues
MTNLNPEIPDRNLALELVRVTEAAALASGRWVGRGMKNEGDGAAVDAMRKLINSVQMNGVVVIGEGEKDEAPMLFNGEQV
GTGEGAAVDIAVDPVDGTTLMAEGRPNAISVLAAAERGSMYDPSAVFYMRKIAVGPEAAGTIDINAPVEYNIKAVAKAKG
IAPDQVTVVVLDRPRHETLIKDIREAGAKVRLIRDGDVAGAVAAAQATNSVDIMMGTGGTPEGIITACAMKCMGGEIQGV
LAPKDDAEAAKARNAGHELNRVLGTHDLVSSDNCFFVATGVTNGDMLRGVSYRADGATTRSLVMRSKSGTVRFIESTHKL
HKLQEYSVVDYSQISPRK
>Mature_337_residues
TNLNPEIPDRNLALELVRVTEAAALASGRWVGRGMKNEGDGAAVDAMRKLINSVQMNGVVVIGEGEKDEAPMLFNGEQVG
TGEGAAVDIAVDPVDGTTLMAEGRPNAISVLAAAERGSMYDPSAVFYMRKIAVGPEAAGTIDINAPVEYNIKAVAKAKGI
APDQVTVVVLDRPRHETLIKDIREAGAKVRLIRDGDVAGAVAAAQATNSVDIMMGTGGTPEGIITACAMKCMGGEIQGVL
APKDDAEAAKARNAGHELNRVLGTHDLVSSDNCFFVATGVTNGDMLRGVSYRADGATTRSLVMRSKSGTVRFIESTHKLH
KLQEYSVVDYSQISPRK

Specific function: Catalyzes the hydrolysis of fructose 1,6-bisphosphate to fructose 6-phosphate. Is essential for growth on gluconeogenic carbon sources. Also displays a low activity toward glucose 6- phosphate, and fructose 6-phosphate, glycerol 3-phosphate, ribulose 1,5-

COG id: COG1494

COG function: function code G; Fructose-1,6-bisphosphatase/sedoheptulose 1,7-bisphosphatase and related proteins

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FBPase class 2 family [H]

Homologues:

Organism=Escherichia coli, GI1790360, Length=325, Percent_Identity=44.6153846153846, Blast_Score=278, Evalue=3e-76,
Organism=Escherichia coli, GI1789298, Length=320, Percent_Identity=42.1875, Blast_Score=231, Evalue=5e-62,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004464 [H]

Pfam domain/function: PF03320 FBPase_glpX [H]

EC number: =3.1.3.11 [H]

Molecular weight: Translated: 35589; Mature: 35458

Theoretical pI: Translated: 5.47; Mature: 5.47

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTNLNPEIPDRNLALELVRVTEAAALASGRWVGRGMKNEGDGAAVDAMRKLINSVQMNGV
CCCCCCCCCCCCCEEEEEHHHHHHHHHCCCEECCCCCCCCCCHHHHHHHHHHHHHCCCCE
VVIGEGEKDEAPMLFNGEQVGTGEGAAVDIAVDPVDGTTLMAEGRPNAISVLAAAERGSM
EEEECCCCCCCCEEECCCEECCCCCCEEEEEEECCCCCEEEECCCCCEEEEEEECCCCCC
YDPSAVFYMRKIAVGPEAAGTIDINAPVEYNIKAVAKAKGIAPDQVTVVVLDRPRHETLI
CCCHHHHEEHHHHCCCCCCCEEEECCCCEECEEEEEHHCCCCCCCEEEEEECCCCHHHHH
KDIREAGAKVRLIRDGDVAGAVAAAQATNSVDIMMGTGGTPEGIITACAMKCMGGEIQGV
HHHHHCCCEEEEEECCCCCHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHHCCCCEEEE
LAPKDDAEAAKARNAGHELNRVLGTHDLVSSDNCFFVATGVTNGDMLRGVSYRADGATTR
ECCCCCHHHHHHHCCHHHHHHHHCCHHCCCCCCEEEEEECCCCCHHHCCEEECCCCCCEE
SLVMRSKSGTVRFIESTHKLHKLQEYSVVDYSQISPRK
HHEEECCCCCEEEEHHHHHHHHHHHCCCCCCCCCCCCC
>Mature Secondary Structure 
TNLNPEIPDRNLALELVRVTEAAALASGRWVGRGMKNEGDGAAVDAMRKLINSVQMNGV
CCCCCCCCCCCCEEEEEHHHHHHHHHCCCEECCCCCCCCCCHHHHHHHHHHHHHCCCCE
VVIGEGEKDEAPMLFNGEQVGTGEGAAVDIAVDPVDGTTLMAEGRPNAISVLAAAERGSM
EEEECCCCCCCCEEECCCEECCCCCCEEEEEEECCCCCEEEECCCCCEEEEEEECCCCCC
YDPSAVFYMRKIAVGPEAAGTIDINAPVEYNIKAVAKAKGIAPDQVTVVVLDRPRHETLI
CCCHHHHEEHHHHCCCCCCCEEEECCCCEECEEEEEHHCCCCCCCEEEEEECCCCHHHHH
KDIREAGAKVRLIRDGDVAGAVAAAQATNSVDIMMGTGGTPEGIITACAMKCMGGEIQGV
HHHHHCCCEEEEEECCCCCHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHHCCCCEEEE
LAPKDDAEAAKARNAGHELNRVLGTHDLVSSDNCFFVATGVTNGDMLRGVSYRADGATTR
ECCCCCHHHHHHHCCHHHHHHHHCCHHCCCCCCEEEEEECCCCCHHHCCEEECCCCCCEE
SLVMRSKSGTVRFIESTHKLHKLQEYSVVDYSQISPRK
HHEEECCCCCEEEEHHHHHHHHHHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12948626 [H]