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The map label for this gene is coaA

Identifier: 38233527

GI number: 38233527

Start: 902362

End: 903288

Strand: Reverse

Name: coaA

Synonym: DIP0931

Alternate gene names: 38233527

Gene position: 903288-902362 (Counterclockwise)

Preceding gene: 38233529

Following gene: 38233522

Centisome position: 36.3

GC content: 53.61

Gene sequence:

>927_bases
ATGGCTCGCGACAAAGACCTCAGCCCATATCTCGACTTTGATCGTGAGACGTGGCGTCATTTGCGCATGTCGATGCCCCA
GGTACTCACAGAGCAAGAGGTCGTGGAACTACGTGGTATTGGCGAAAACATCGATCTCGACGAAGTCGCCGAGGTTTATC
TACCGCTGTCGCGTCTCATTCATCTCCAAGTCCACGCGCGCCAAGAACTCACGCAGGCAACCGAAACCTTCTTAGGTGAA
AAAGCACCCCACATCCCGTTTGTTATCGGCGTTGCTGGATCTGTGGCAGTAGGAAAATCCACCACAGCACGTTTGCTCCA
AGTCCTTTTACAGCGGTGGGACGAACATCCTCGCGTAGATTTGGTCACCACCGATGGATTCCTCCACCCCACCGAGATTC
TGAAAAAACGCGGCATTTTGGACCGCAAAGGATTCCCAGAAAGCTACGATCAACGCGCGCTATTGCGCTTTGTCACTGAT
GTAAAAGCCGGAAAAGCGCACGTTAAAGCCCCAGTGTATTCGCACACTCTATACGACCGTGTAGAAAACGAATGTGTCAC
GGTCAGCCGCCCCGACATTTTGATCGTTGAGGGTCTTAATGTGTTGCAGACCGGCCCCACCTTGTCGGTCAGTGACCTTT
TTGACTTCAGTGTCTATGTCGACGCTGCCCTCGAAGACATCGAACGCTGGTATATCGATCGCTTCCTGAAACTCCGGCAG
CTAGCATTCCGCGCCCCCAATGCCCACTTCTCCCACTACGCGGACATGGGCGATCGCGCAGCGACTGACGAAGCACGACG
AATCTGGCAAACGATCAATCTCCCCAACCTTGTAGAACACATCCTGCCCACTCGGGTTCGAGCGTCTCTAGTGCTGTGCA
AAGGCGCAGACCATAAAGTCGCTCGCGTGCGCATGCGCAAAATTTAA

Upstream 100 bases:

>100_bases
ATATATCTAACCATTGATAGATTTCCATACTCCACTCCCCCTTATGGTGTTTTTTCACACTGATTTTTCCTCACGGGCTA
CGGAAGGCACAATAGAACCC

Downstream 100 bases:

>100_bases
ACGCAATTCTGGCGTTCCAGCACCCAGTGCTGAATTGCATCGAGTTCGGAAAAATCTACCCAATCGGTATCACGCTGGAA
CATCGAAATCATGCTCTTGT

Product: pantothenate kinase

Products: NA

Alternate protein names: Pantothenic acid kinase

Number of amino acids: Translated: 308; Mature: 307

Protein sequence:

>308_residues
MARDKDLSPYLDFDRETWRHLRMSMPQVLTEQEVVELRGIGENIDLDEVAEVYLPLSRLIHLQVHARQELTQATETFLGE
KAPHIPFVIGVAGSVAVGKSTTARLLQVLLQRWDEHPRVDLVTTDGFLHPTEILKKRGILDRKGFPESYDQRALLRFVTD
VKAGKAHVKAPVYSHTLYDRVENECVTVSRPDILIVEGLNVLQTGPTLSVSDLFDFSVYVDAALEDIERWYIDRFLKLRQ
LAFRAPNAHFSHYADMGDRAATDEARRIWQTINLPNLVEHILPTRVRASLVLCKGADHKVARVRMRKI

Sequences:

>Translated_308_residues
MARDKDLSPYLDFDRETWRHLRMSMPQVLTEQEVVELRGIGENIDLDEVAEVYLPLSRLIHLQVHARQELTQATETFLGE
KAPHIPFVIGVAGSVAVGKSTTARLLQVLLQRWDEHPRVDLVTTDGFLHPTEILKKRGILDRKGFPESYDQRALLRFVTD
VKAGKAHVKAPVYSHTLYDRVENECVTVSRPDILIVEGLNVLQTGPTLSVSDLFDFSVYVDAALEDIERWYIDRFLKLRQ
LAFRAPNAHFSHYADMGDRAATDEARRIWQTINLPNLVEHILPTRVRASLVLCKGADHKVARVRMRKI
>Mature_307_residues
ARDKDLSPYLDFDRETWRHLRMSMPQVLTEQEVVELRGIGENIDLDEVAEVYLPLSRLIHLQVHARQELTQATETFLGEK
APHIPFVIGVAGSVAVGKSTTARLLQVLLQRWDEHPRVDLVTTDGFLHPTEILKKRGILDRKGFPESYDQRALLRFVTDV
KAGKAHVKAPVYSHTLYDRVENECVTVSRPDILIVEGLNVLQTGPTLSVSDLFDFSVYVDAALEDIERWYIDRFLKLRQL
AFRAPNAHFSHYADMGDRAATDEARRIWQTINLPNLVEHILPTRVRASLVLCKGADHKVARVRMRKI

Specific function: Coenzyme A (CoA) biosynthesis; first step. [C]

COG id: COG1072

COG function: function code H; Panthothenate kinase

Gene ontology:

Cell location: Cytoplasm (Probable)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the prokaryotic pantothenate kinase family

Homologues:

Organism=Escherichia coli, GI1790409, Length=308, Percent_Identity=51.9480519480519, Blast_Score=332, Evalue=2e-92,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): COAA_CORDI (Q6NI48)

Other databases:

- EMBL:   BX248356
- RefSeq:   NP_939294.1
- HSSP:   P0A6I3
- ProteinModelPortal:   Q6NI48
- SMR:   Q6NI48
- GeneID:   2649971
- GenomeReviews:   BX248353_GR
- KEGG:   cdi:DIP0931
- NMPDR:   fig|257309.1.peg.885
- HOGENOM:   HBG732538
- OMA:   GLNVLQP
- PhylomeDB:   Q6NI48
- ProtClustDB:   PRK05439
- BioCyc:   CDIP257309:DIP0931-MONOMER
- BRENDA:   2.7.1.33
- GO:   GO:0005737
- HAMAP:   MF_00215
- InterPro:   IPR004566
- InterPro:   IPR006083
- PANTHER:   PTHR10285:SF7
- PIRSF:   PIRSF000545
- TIGRFAMs:   TIGR00554

Pfam domain/function: PF00485 PRK

EC number: =2.7.1.33

Molecular weight: Translated: 35233; Mature: 35102

Theoretical pI: Translated: 7.17; Mature: 7.17

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MARDKDLSPYLDFDRETWRHLRMSMPQVLTEQEVVELRGIGENIDLDEVAEVYLPLSRLI
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHH
HLQVHARQELTQATETFLGEKAPHIPFVIGVAGSVAVGKSTTARLLQVLLQRWDEHPRVD
HHHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCCCCCCHHHHHHHHHHHHHCCCCCCEE
LVTTDGFLHPTEILKKRGILDRKGFPESYDQRALLRFVTDVKAGKAHVKAPVYSHTLYDR
EEECCCCCCHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHCCCHHHCCCHHHHHHHHH
VENECVTVSRPDILIVEGLNVLQTGPTLSVSDLFDFSVYVDAALEDIERWYIDRFLKLRQ
HCCCEEEECCCCEEEECCCHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LAFRAPNAHFSHYADMGDRAATDEARRIWQTINLPNLVEHILPTRVRASLVLCKGADHKV
HHHCCCCCHHHHHHHCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHEEEECCCCCHH
ARVRMRKI
HHHHHHCC
>Mature Secondary Structure 
ARDKDLSPYLDFDRETWRHLRMSMPQVLTEQEVVELRGIGENIDLDEVAEVYLPLSRLI
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHH
HLQVHARQELTQATETFLGEKAPHIPFVIGVAGSVAVGKSTTARLLQVLLQRWDEHPRVD
HHHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCCCCCCHHHHHHHHHHHHHCCCCCCEE
LVTTDGFLHPTEILKKRGILDRKGFPESYDQRALLRFVTDVKAGKAHVKAPVYSHTLYDR
EEECCCCCCHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHCCCHHHCCCHHHHHHHHH
VENECVTVSRPDILIVEGLNVLQTGPTLSVSDLFDFSVYVDAALEDIERWYIDRFLKLRQ
HCCCEEEECCCCEEEECCCHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LAFRAPNAHFSHYADMGDRAATDEARRIWQTINLPNLVEHILPTRVRASLVLCKGADHKV
HHHCCCCCHHHHHHHCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHEEEECCCCCHH
ARVRMRKI
HHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 14602910