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The map label for this gene is ripA

Identifier: 38233518

GI number: 38233518

Start: 895787

End: 896794

Strand: Direct

Name: ripA

Synonym: DIP0922

Alternate gene names: 38233518

Gene position: 895787-896794 (Clockwise)

Preceding gene: 38233517

Following gene: 38233519

Centisome position: 36.0

GC content: 53.08

Gene sequence:

>1008_bases
GTGAGTCTTCCATCAATTAAGACGACCAATAGTTACTGTGTGGTGCTGTGGTGCGATCAGGGTAGCGCAACGATTAACGC
TCCAGATCGGGTGGTCCAGGTGATGGCTGGTGATGTTGTGCTTGCTCCGCACGGTGCTTTTGTTACTGGCCATGGAGTGG
TTTTGCCGATGGCTTTTCCTGATTTTGATGGAGGGGAGCACACTCGTCGCCTGCATATGGGGACTGCGTGGTCGAAGCGA
ATGATTTTTGAGTTTTCGCGCAGTCTATTAGGTGAGACGCGCCCATCGGAATGCATTGCAGCGCTTTTCGACGATCGCGC
GCGGCCGCCACGGGTTCCTGAACCGCAGGCAGCACGGAAGGTTGCTCAGAAGCTGATTGCTTATCCGGCGGATCAAACAC
CTTTGTTGGAATTTGCTCAGCTTCACAACATTAGTAGCAGGACATTGCAGCGTCAGTTCGTCGCGTCGACTGGTTTTACG
TTTAGTGAATGGCGTGCAGCATTGCGTGTGTCTGTGGCGGCTGATTTATTGGCTCATGATTTCCGGATCGGTCAGGTTTC
ACAGATGGTGGGCTTTAGTGCGACGTCGTCACTTACGCGCGCATTTAAGCGTCATACTGGTGATACTCCTTCTTCTTTTA
CCTCGCCGCGTATGCATGCTGTGTGCGAGCAGCAGCCGCCGATGATTCCAGCAACTACAACGTTTGCGCGGGCTTCGGAC
GACATTGCTTTGTGGATTTATAGTGGAACGGCGACTGTTACCACCCCTGGTTATTGCCGATTTATGGGTGCGGGGGAGAC
TGTCACTATTCCCTCTGGTACAAGTACGCGTCTCGACGTTTCTGCTGGTTCTGTAGCATTGCCAGTCCCGCTTGCTGCGG
CTCATGACGACTTAACGCTGAGCGATGTTCTAGCTGCTTCTGTTAATCCACTTGCTGCGGTGGAATTGCAACGATTGAGC
GCCCAAGAACGCGCGGATGTTGAGCAGGTGTTGGTTCCTTCTGTGTAA

Upstream 100 bases:

>100_bases
AGGAGTAACCTTAGGCTTGCCTTTGTAACCATCCTTTGGTTTGATGGCATCTATACAGACCGTATAGGTGCCATTTGTAT
GTTCAAAGGGGTTTCGGCTC

Downstream 100 bases:

>100_bases
GTTGATAAAAAATTTTTAAAAATAGCTTTTTCTAGGGAACTAAAAAGCATTGCGATGCGTTATTGCAGATGTACGAAGAT
GTTCCTTTGGCAAAGATGTA

Product: AraC family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 335; Mature: 334

Protein sequence:

>335_residues
MSLPSIKTTNSYCVVLWCDQGSATINAPDRVVQVMAGDVVLAPHGAFVTGHGVVLPMAFPDFDGGEHTRRLHMGTAWSKR
MIFEFSRSLLGETRPSECIAALFDDRARPPRVPEPQAARKVAQKLIAYPADQTPLLEFAQLHNISSRTLQRQFVASTGFT
FSEWRAALRVSVAADLLAHDFRIGQVSQMVGFSATSSLTRAFKRHTGDTPSSFTSPRMHAVCEQQPPMIPATTTFARASD
DIALWIYSGTATVTTPGYCRFMGAGETVTIPSGTSTRLDVSAGSVALPVPLAAAHDDLTLSDVLAASVNPLAAVELQRLS
AQERADVEQVLVPSV

Sequences:

>Translated_335_residues
MSLPSIKTTNSYCVVLWCDQGSATINAPDRVVQVMAGDVVLAPHGAFVTGHGVVLPMAFPDFDGGEHTRRLHMGTAWSKR
MIFEFSRSLLGETRPSECIAALFDDRARPPRVPEPQAARKVAQKLIAYPADQTPLLEFAQLHNISSRTLQRQFVASTGFT
FSEWRAALRVSVAADLLAHDFRIGQVSQMVGFSATSSLTRAFKRHTGDTPSSFTSPRMHAVCEQQPPMIPATTTFARASD
DIALWIYSGTATVTTPGYCRFMGAGETVTIPSGTSTRLDVSAGSVALPVPLAAAHDDLTLSDVLAASVNPLAAVELQRLS
AQERADVEQVLVPSV
>Mature_334_residues
SLPSIKTTNSYCVVLWCDQGSATINAPDRVVQVMAGDVVLAPHGAFVTGHGVVLPMAFPDFDGGEHTRRLHMGTAWSKRM
IFEFSRSLLGETRPSECIAALFDDRARPPRVPEPQAARKVAQKLIAYPADQTPLLEFAQLHNISSRTLQRQFVASTGFTF
SEWRAALRVSVAADLLAHDFRIGQVSQMVGFSATSSLTRAFKRHTGDTPSSFTSPRMHAVCEQQPPMIPATTTFARASDD
IALWIYSGTATVTTPGYCRFMGAGETVTIPSGTSTRLDVSAGSVALPVPLAAAHDDLTLSDVLAASVNPLAAVELQRLSA
QERADVEQVLVPSV

Specific function: Under iron limitation, represses the acn (aconitase), catA (catechol 1,2 dioxygenase), leuCD (isopropylmalate dehydratase), narKGHJI (nitrite/nitrate transporter and nitrate reductase), sdhCAB (succinate dehydrogenase), pta (phosphotransacetylase) and kat

COG id: COG2207

COG function: function code K; AraC-type DNA-binding domain-containing proteins

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH araC/xylS-type DNA-binding domain

Homologues:

None

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): RIPA_CORDI (Q6NI56)

Other databases:

- EMBL:   BX248356
- RefSeq:   NP_939285.1
- ProteinModelPortal:   Q6NI56
- SMR:   Q6NI56
- GeneID:   2649962
- GenomeReviews:   BX248353_GR
- KEGG:   cdi:DIP0922
- NMPDR:   fig|257309.1.peg.876
- HOGENOM:   HBG428997
- OMA:   TTPGYCR
- ProtClustDB:   CLSK633150
- BioCyc:   CDIP257309:DIP0922-MONOMER
- GO:   GO:0005622
- InterPro:   IPR009057
- InterPro:   IPR012287
- InterPro:   IPR018062
- InterPro:   IPR018060
- Gene3D:   G3DSA:1.10.10.60
- SMART:   SM00342

Pfam domain/function: PF00165 HTH_AraC; SSF46689 Homeodomain_like

EC number: NA

Molecular weight: Translated: 36067; Mature: 35936

Theoretical pI: Translated: 7.00; Mature: 7.00

Prosite motif: PS00041 HTH_ARAC_FAMILY_1; PS01124 HTH_ARAC_FAMILY_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLPSIKTTNSYCVVLWCDQGSATINAPDRVVQVMAGDVVLAPHGAFVTGHGVVLPMAFP
CCCCCCCCCCCEEEEEEECCCCCEECCHHHHHHHHHCCEEEECCCCEEECCCEEEEEECC
DFDGGEHTRRLHMGTAWSKRMIFEFSRSLLGETRPSECIAALFDDRARPPRVPEPQAARK
CCCCCCCCEEEECCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCCHHHHHH
VAQKLIAYPADQTPLLEFAQLHNISSRTLQRQFVASTGFTFSEWRAALRVSVAADLLAHD
HHHHHHHCCCCCCHHHHHHHHHCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHH
FRIGQVSQMVGFSATSSLTRAFKRHTGDTPSSFTSPRMHAVCEQQPPMIPATTTFARASD
CCCCHHHHHHCCHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHCCCCCCCCCCCHHHCCCC
DIALWIYSGTATVTTPGYCRFMGAGETVTIPSGTSTRLDVSAGSVALPVPLAAAHDDLTL
CEEEEEEECCEEEECCCEEEEECCCCEEEECCCCCCEEEECCCCEEECCCEECCCCCCHH
SDVLAASVNPLAAVELQRLSAQERADVEQVLVPSV
HHHHHHCCCCHHHHHHHHHCCHHHCCHHHHHCCCC
>Mature Secondary Structure 
SLPSIKTTNSYCVVLWCDQGSATINAPDRVVQVMAGDVVLAPHGAFVTGHGVVLPMAFP
CCCCCCCCCCEEEEEEECCCCCEECCHHHHHHHHHCCEEEECCCCEEECCCEEEEEECC
DFDGGEHTRRLHMGTAWSKRMIFEFSRSLLGETRPSECIAALFDDRARPPRVPEPQAARK
CCCCCCCCEEEECCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCCHHHHHH
VAQKLIAYPADQTPLLEFAQLHNISSRTLQRQFVASTGFTFSEWRAALRVSVAADLLAHD
HHHHHHHCCCCCCHHHHHHHHHCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHH
FRIGQVSQMVGFSATSSLTRAFKRHTGDTPSSFTSPRMHAVCEQQPPMIPATTTFARASD
CCCCHHHHHHCCHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHCCCCCCCCCCCHHHCCCC
DIALWIYSGTATVTTPGYCRFMGAGETVTIPSGTSTRLDVSAGSVALPVPLAAAHDDLTL
CEEEEEEECCEEEECCCEEEEECCCCEEEECCCCCCEEEECCCCEEECCCEECCCCCCHH
SDVLAASVNPLAAVELQRLSAQERADVEQVLVPSV
HHHHHHCCCCHHHHHHHHHCCHHHCCHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 14602910