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The map label for this gene is betP [H]

Identifier: 38233466

GI number: 38233466

Start: 841745

End: 843490

Strand: Direct

Name: betP [H]

Synonym: DIP0869

Alternate gene names: 38233466

Gene position: 841745-843490 (Clockwise)

Preceding gene: 38233464

Following gene: 38233467

Centisome position: 33.82

GC content: 52.29

Gene sequence:

>1746_bases
ATGATCGAGGGCGAAGGACTTATCGCTGAGGCAACCGCAGCACCGGAAAAAGAAATTACTTTCGAAGGTGAAGATGACAA
CGCAGGAGTGGACTGGAAAGTCACAGCCCCTGCCATGGTGATTGTTCTCGCTGTTGTCGCGTGGGGAATCCTCGGAACGA
CAAGCTTTGCCTCCTTTGCGGCATCCTCACTGGGTTACATTGTGGATAGCTTCGGCTGGGCATTTATTTTCTTTACTACG
GTGTTCTTGATCTTCGCCATTGCTATTGCATTGAGCAACTTTGGCACAATCAAGCTCGGACGCAATGATGAAGCCCCTGA
GTTTTCCACCACGTCGTGGATCGCCATGATGTTTGCTGCCGGCATGGGCATTGGTTTGATGTTCTATGGGGCATCCGAAC
CACTGAGCAATTACCTCAACGGCGTTCCAGGACATGAGCCACGTTCCGTGGGGCATGCCATGAGCACCACCTTGCTGCAC
TGGACGCTGCACCCATGGGCAATTTATGGCATTTTTGGCCTTGCTATTGCATATAGCACGTTCCGCTTGGGACGTCGTCA
GCTATTGAGCTCGGCGTTTATCCCACTGATCGGTGAACACGGAGCAAAAGGATGGATCGGCCGCATTGTCGATATTTTGG
CGATTATTGCCACCATCTTCGGTACTGCTTGTTCACTGGGCGTCGGTGCTACCCAGATCAGCGCTGGTCTTGATGCCGCA
GGTGTGGTGAAAGATCCAGGAATGAGCACGGTTTTGGCCATCGTGTCGGTATTAACCTTGGCCTTCTTGTTGTCGGCAAT
GTCTGGCGTAGGCAAAGGCATTCAGTACGTATCTAATGCCAACATGGTCCTTGCGGCACTCTTGGCAATTTTCGTATTCG
TTTTGGGACCGACCGTCACCATCTTGAACCTGATCCCAGGCTCGCTGGGCGCATACCTATCCAACTTCTTTGAGATGGTC
GGCCGTACTGCAGAATCTGCCGATGGATCGGCAGGAGAGTGGCTGGGCAGCTGGACCATCTTCTACTGGGCATGGTGGAT
CTCGTGGAGCCCATTTGTGGGCATGTTCTTAGCGCGTATTTCACGTGGCCGTACGATTCGTGAATTCCTGTTCGGCGTCA
TGCTTGTACCGGCAGCGGTGTCTGTTGTTTGGTTCGCCATCTTTGGTGGTACTGCTATTCACTTCGAACAAGAGGGTCGC
TCTATCTACGGCGACGGCTCTGCTGAATACCAGCTCTTCGAACTGTTGCATGCACTGCCAGGTGGCAAGATTGCCGGCGT
TGTTGCTGTGATTTTGTTGGCTACCTTCTTTATTACCTCTGCCGATTCGGCTTCCACGGTGATGGGATCCATGAGTCAAA
ATGGTCAAACAGATGCGAATAAATATGTGTCGGCTGCGTGGGGTCTGTTGGTTGCCTTGATCGGTATGACCATGTTGGTT
TCTGGTGGCGACGATGTTTTGAGCAACTTGCAAAATATCACCATCATTGCTGCAAGTCCGTTCCTGGTGGTGATCGTCAT
TTTGATGTTTGCCGTGTTGAAAGACCTCAGAAACGATGAGATCTACTTGGATTACCGTGAGCAGCAGCGCTTTGCTTCAC
GTTTGGCTCGTGAGCGTCGTATCCACTTGGAGCACGAGAAGCGGAAGAAGGCCCGTGAGAAGCGTCGTAACGCGAAGGAG
CACAAAGAGCACAAGGTTCGCGTGCCACGTGCTGGAAAGGGTGACCACCTACGGCACCGTCGATAA

Upstream 100 bases:

>100_bases
GTTCAGTACGGATCCTTCGTCCGGATCCAGTGAGAGCACGGCACTGGAATCGACAACCTCGTCAGCACCTGTCGTCAGCG
CAACGGCAGAGCTTGCCGCC

Downstream 100 bases:

>100_bases
GCAGGCATCGTAAAGATGTCAGAGCACAATTAAACAAAAATTTCACACACGTATTTTGAAAGGTGAGCACCTTTAACCAT
GCTCAAAAAAACAATTACTA

Product: glycine betaine transporter

Products: Proton [Cytoplasm]; choline [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 581; Mature: 581

Protein sequence:

>581_residues
MIEGEGLIAEATAAPEKEITFEGEDDNAGVDWKVTAPAMVIVLAVVAWGILGTTSFASFAASSLGYIVDSFGWAFIFFTT
VFLIFAIAIALSNFGTIKLGRNDEAPEFSTTSWIAMMFAAGMGIGLMFYGASEPLSNYLNGVPGHEPRSVGHAMSTTLLH
WTLHPWAIYGIFGLAIAYSTFRLGRRQLLSSAFIPLIGEHGAKGWIGRIVDILAIIATIFGTACSLGVGATQISAGLDAA
GVVKDPGMSTVLAIVSVLTLAFLLSAMSGVGKGIQYVSNANMVLAALLAIFVFVLGPTVTILNLIPGSLGAYLSNFFEMV
GRTAESADGSAGEWLGSWTIFYWAWWISWSPFVGMFLARISRGRTIREFLFGVMLVPAAVSVVWFAIFGGTAIHFEQEGR
SIYGDGSAEYQLFELLHALPGGKIAGVVAVILLATFFITSADSASTVMGSMSQNGQTDANKYVSAAWGLLVALIGMTMLV
SGGDDVLSNLQNITIIAASPFLVVIVILMFAVLKDLRNDEIYLDYREQQRFASRLARERRIHLEHEKRKKAREKRRNAKE
HKEHKVRVPRAGKGDHLRHRR

Sequences:

>Translated_581_residues
MIEGEGLIAEATAAPEKEITFEGEDDNAGVDWKVTAPAMVIVLAVVAWGILGTTSFASFAASSLGYIVDSFGWAFIFFTT
VFLIFAIAIALSNFGTIKLGRNDEAPEFSTTSWIAMMFAAGMGIGLMFYGASEPLSNYLNGVPGHEPRSVGHAMSTTLLH
WTLHPWAIYGIFGLAIAYSTFRLGRRQLLSSAFIPLIGEHGAKGWIGRIVDILAIIATIFGTACSLGVGATQISAGLDAA
GVVKDPGMSTVLAIVSVLTLAFLLSAMSGVGKGIQYVSNANMVLAALLAIFVFVLGPTVTILNLIPGSLGAYLSNFFEMV
GRTAESADGSAGEWLGSWTIFYWAWWISWSPFVGMFLARISRGRTIREFLFGVMLVPAAVSVVWFAIFGGTAIHFEQEGR
SIYGDGSAEYQLFELLHALPGGKIAGVVAVILLATFFITSADSASTVMGSMSQNGQTDANKYVSAAWGLLVALIGMTMLV
SGGDDVLSNLQNITIIAASPFLVVIVILMFAVLKDLRNDEIYLDYREQQRFASRLARERRIHLEHEKRKKAREKRRNAKE
HKEHKVRVPRAGKGDHLRHRR
>Mature_581_residues
MIEGEGLIAEATAAPEKEITFEGEDDNAGVDWKVTAPAMVIVLAVVAWGILGTTSFASFAASSLGYIVDSFGWAFIFFTT
VFLIFAIAIALSNFGTIKLGRNDEAPEFSTTSWIAMMFAAGMGIGLMFYGASEPLSNYLNGVPGHEPRSVGHAMSTTLLH
WTLHPWAIYGIFGLAIAYSTFRLGRRQLLSSAFIPLIGEHGAKGWIGRIVDILAIIATIFGTACSLGVGATQISAGLDAA
GVVKDPGMSTVLAIVSVLTLAFLLSAMSGVGKGIQYVSNANMVLAALLAIFVFVLGPTVTILNLIPGSLGAYLSNFFEMV
GRTAESADGSAGEWLGSWTIFYWAWWISWSPFVGMFLARISRGRTIREFLFGVMLVPAAVSVVWFAIFGGTAIHFEQEGR
SIYGDGSAEYQLFELLHALPGGKIAGVVAVILLATFFITSADSASTVMGSMSQNGQTDANKYVSAAWGLLVALIGMTMLV
SGGDDVLSNLQNITIIAASPFLVVIVILMFAVLKDLRNDEIYLDYREQQRFASRLARERRIHLEHEKRKKAREKRRNAKE
HKEHKVRVPRAGKGDHLRHRR

Specific function: High-affinity uptake of glycine betaine [H]

COG id: COG1292

COG function: function code M; Choline-glycine betaine transporter

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the BCCT transporter (TC 2.A.15) family [H]

Homologues:

Organism=Escherichia coli, GI1786506, Length=518, Percent_Identity=35.3281853281853, Blast_Score=308, Evalue=8e-85,
Organism=Escherichia coli, GI1786224, Length=519, Percent_Identity=29.0944123314065, Blast_Score=183, Evalue=3e-47,
Organism=Escherichia coli, GI1788102, Length=457, Percent_Identity=30.1969365426696, Blast_Score=173, Evalue=3e-44,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000060
- InterPro:   IPR018093 [H]

Pfam domain/function: PF02028 BCCT [H]

EC number: NA

Molecular weight: Translated: 62842; Mature: 62842

Theoretical pI: Translated: 7.50; Mature: 7.50

Prosite motif: PS01303 BCCT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIEGEGLIAEATAAPEKEITFEGEDDNAGVDWKVTAPAMVIVLAVVAWGILGTTSFASFA
CCCCCCCEEECCCCCCCCEEECCCCCCCCCCEEECHHHHHHHHHHHHHHHHHHHHHHHHH
ASSLGYIVDSFGWAFIFFTTVFLIFAIAIALSNFGTIKLGRNDEAPEFSTTSWIAMMFAA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCHHHHHHHHHHH
GMGIGLMFYGASEPLSNYLNGVPGHEPRSVGHAMSTTLLHWTLHPWAIYGIFGLAIAYST
CCCHHEEEECCCCHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHH
FRLGRRQLLSSAFIPLIGEHGAKGWIGRIVDILAIIATIFGTACSLGVGATQISAGLDAA
HHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCCCCC
GVVKDPGMSTVLAIVSVLTLAFLLSAMSGVGKGIQYVSNANMVLAALLAIFVFVLGPTVT
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHH
ILNLIPGSLGAYLSNFFEMVGRTAESADGSAGEWLGSWTIFYWAWWISWSPFVGMFLARI
HHHHCCCHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SRGRTIREFLFGVMLVPAAVSVVWFAIFGGTAIHFEQEGRSIYGDGSAEYQLFELLHALP
HCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCEEECCCCCHHHHHHHHHHCC
GGKIAGVVAVILLATFFITSADSASTVMGSMSQNGQTDANKYVSAAWGLLVALIGMTMLV
CCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
SGGDDVLSNLQNITIIAASPFLVVIVILMFAVLKDLRNDEIYLDYREQQRFASRLARERR
CCCHHHHHCCCCEEEEECCHHHHHHHHHHHHHHHHCCCCCEEEEHHHHHHHHHHHHHHHH
IHLEHEKRKKAREKRRNAKEHKEHKVRVPRAGKGDHLRHRR
HCCHHHHHHHHHHHHHCHHHHHHHCEECCCCCCCCCCCCCC
>Mature Secondary Structure
MIEGEGLIAEATAAPEKEITFEGEDDNAGVDWKVTAPAMVIVLAVVAWGILGTTSFASFA
CCCCCCCEEECCCCCCCCEEECCCCCCCCCCEEECHHHHHHHHHHHHHHHHHHHHHHHHH
ASSLGYIVDSFGWAFIFFTTVFLIFAIAIALSNFGTIKLGRNDEAPEFSTTSWIAMMFAA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCHHHHHHHHHHH
GMGIGLMFYGASEPLSNYLNGVPGHEPRSVGHAMSTTLLHWTLHPWAIYGIFGLAIAYST
CCCHHEEEECCCCHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHH
FRLGRRQLLSSAFIPLIGEHGAKGWIGRIVDILAIIATIFGTACSLGVGATQISAGLDAA
HHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCCCCC
GVVKDPGMSTVLAIVSVLTLAFLLSAMSGVGKGIQYVSNANMVLAALLAIFVFVLGPTVT
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHH
ILNLIPGSLGAYLSNFFEMVGRTAESADGSAGEWLGSWTIFYWAWWISWSPFVGMFLARI
HHHHCCCHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SRGRTIREFLFGVMLVPAAVSVVWFAIFGGTAIHFEQEGRSIYGDGSAEYQLFELLHALP
HCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCEEECCCCCHHHHHHHHHHCC
GGKIAGVVAVILLATFFITSADSASTVMGSMSQNGQTDANKYVSAAWGLLVALIGMTMLV
CCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
SGGDDVLSNLQNITIIAASPFLVVIVILMFAVLKDLRNDEIYLDYREQQRFASRLARERR
CCCHHHHHCCCCEEEEECCHHHHHHHHHHHHHHHHCCCCCEEEEHHHHHHHHHHHHHHHH
IHLEHEKRKKAREKRRNAKEHKEHKVRVPRAGKGDHLRHRR
HCCHHHHHHHHHHHHHCHHHHHHHCEECCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; choline [Periplasm] [C]

Specific reaction: Proton [Periplasm] + choline [Periplasm] = Proton [Cytoplasm] + choline [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12948626 [H]