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The map label for this gene is ygbD [C]

Identifier: 21674888

GI number: 21674888

Start: 1969618

End: 1970976

Strand: Direct

Name: ygbD [C]

Synonym: CT2078

Alternate gene names: 21674888

Gene position: 1969618-1970976 (Clockwise)

Preceding gene: 21674887

Following gene: 21674890

Centisome position: 91.4

GC content: 62.4

Gene sequence:

>1359_bases
ATGAACAAACAGGTCGATGTTCTTGTCATTGGCGGCAGCGCGGCTGGCATTGTCGCCGCCACCACCGGCAAGGCATTCTA
TGCATCCAAATCGTTTCTCATCGTCCGCAAGGAACCCGAAGCGGTCGTGCCGTGCGGGATTCCCTATATTTTCGGCACCC
TCGATGGCGTACACCAGAACATCGTTCCCACCGCGCCGCTGGCCAACGCTGACGTCGAGCTGCTCATCGACGAAGTCGTT
TCAATTGACCGCGAAGCCAAGTCAGCCACCACCGCCGGAGGCGTGGTCATCTCGTGGGACAAGCTCGTGCTCGCGACCGG
CTCCGAACCGAAAACCCCCGACTGGCTCGAAGGGCGCGACCTCGACGGCGTGTTCGTCATCCCGAAAAACCGCGACTACC
TGTGCCGTCTCCGCTCGCGGCTCGAAGAGCCTCGCCGGGTGGCCATCATCGGCGGCGGCTTCATCGGCGTCGAACTGGCC
GACGAGCTGGCCAAAAAGGGCCATGACGTGACCCTCGTCGAAATTCTTCCGCATGTCCTCAGCATGGCCTTCGACAGCGA
CCTCTCGCTCAAGGCCGAGGAGCTGCTCGTCAAGAGAGGCGTGAAGCTGAAAACCGGCGAGAAGCTCAAGAAGCTCGCAG
GTCAGGCGAGCGTCTCAAAGGTCATCCTCGAAAGCGGCGAAGAGATCGAGGTCGACATCGTCATTCTGGCCACCGGCTAC
GCGCCCAACGTCGAGCTGGCTCGCTCGGCGGGCATCAAGATCAATGAACTCGGCGCCATCCGGGTTGACGAGTACATGCG
CACCGAAGACAAGAATATCTTCGCCGTCGGCGACTGCGCCGAAAAGTTCTCCTTCATCACCCGCATCGTCAAGGGGCTGA
TGCTCGCCTCGACCGCCTGCTCGGAGGCGCGAATCGCGGGCATGAACCTGTTCGGCCTCTCCCGGCTGCGCACCTTCAGC
GGCACCATCGCCATCTTCTCGACGGCCATCGGCGGCACCACCTTCGCCGCCGCCGGAGTCACCGAACAGCTCGCCCGCGA
GCGCGGCTTCGAGGTCGTTTCGGCAGGCTTCACCGGCATCGACAAGCACCCCGGCACCCTGCCCGAAACCTCCAACCAGT
ACGTCAAGCTGATCGTCAACAGCGAAAACGGCCTGGTGCTCGGCGGCGCGGTCATGGGCGGACAGAGCGCTGGCGAGCTG
ATTAACGTCATTGGCGTCATCATCGAAACCAAGATGACCGTCAACGAACTGCTCACGCTCCAGTTCGGCACCCATCCGCT
GCTCACCGGCCCGCCGACCGCCTACGCCCTCATCAAGGCCGCTGAAGCCGTCGAAATGAAGCTCCGCCACTTCAAGTAA

Upstream 100 bases:

>100_bases
TTCGTTACACGCCCGTAAATCGTTCAGAAAAGCTTGTCGTTCTCCCAACAATAGTGTAATTAGGTGCGGTTTTTTCCCAA
CTCTTTTCCCAAGAAAAATT

Downstream 100 bases:

>100_bases
AGCCAGCCGAAAACCCACCATCCCCCCGGATCACGCCTGATCGGCAATCCGGGGGAAGCCTGGCCTGCCATGCCTGCGCG
ACCCCCCTGAGAACGATTTT

Product: NADH oxidase, putative

Products: NA

Alternate protein names: NOXase [H]

Number of amino acids: Translated: 452; Mature: 452

Protein sequence:

>452_residues
MNKQVDVLVIGGSAAGIVAATTGKAFYASKSFLIVRKEPEAVVPCGIPYIFGTLDGVHQNIVPTAPLANADVELLIDEVV
SIDREAKSATTAGGVVISWDKLVLATGSEPKTPDWLEGRDLDGVFVIPKNRDYLCRLRSRLEEPRRVAIIGGGFIGVELA
DELAKKGHDVTLVEILPHVLSMAFDSDLSLKAEELLVKRGVKLKTGEKLKKLAGQASVSKVILESGEEIEVDIVILATGY
APNVELARSAGIKINELGAIRVDEYMRTEDKNIFAVGDCAEKFSFITRIVKGLMLASTACSEARIAGMNLFGLSRLRTFS
GTIAIFSTAIGGTTFAAAGVTEQLARERGFEVVSAGFTGIDKHPGTLPETSNQYVKLIVNSENGLVLGGAVMGGQSAGEL
INVIGVIIETKMTVNELLTLQFGTHPLLTGPPTAYALIKAAEAVEMKLRHFK

Sequences:

>Translated_452_residues
MNKQVDVLVIGGSAAGIVAATTGKAFYASKSFLIVRKEPEAVVPCGIPYIFGTLDGVHQNIVPTAPLANADVELLIDEVV
SIDREAKSATTAGGVVISWDKLVLATGSEPKTPDWLEGRDLDGVFVIPKNRDYLCRLRSRLEEPRRVAIIGGGFIGVELA
DELAKKGHDVTLVEILPHVLSMAFDSDLSLKAEELLVKRGVKLKTGEKLKKLAGQASVSKVILESGEEIEVDIVILATGY
APNVELARSAGIKINELGAIRVDEYMRTEDKNIFAVGDCAEKFSFITRIVKGLMLASTACSEARIAGMNLFGLSRLRTFS
GTIAIFSTAIGGTTFAAAGVTEQLARERGFEVVSAGFTGIDKHPGTLPETSNQYVKLIVNSENGLVLGGAVMGGQSAGEL
INVIGVIIETKMTVNELLTLQFGTHPLLTGPPTAYALIKAAEAVEMKLRHFK
>Mature_452_residues
MNKQVDVLVIGGSAAGIVAATTGKAFYASKSFLIVRKEPEAVVPCGIPYIFGTLDGVHQNIVPTAPLANADVELLIDEVV
SIDREAKSATTAGGVVISWDKLVLATGSEPKTPDWLEGRDLDGVFVIPKNRDYLCRLRSRLEEPRRVAIIGGGFIGVELA
DELAKKGHDVTLVEILPHVLSMAFDSDLSLKAEELLVKRGVKLKTGEKLKKLAGQASVSKVILESGEEIEVDIVILATGY
APNVELARSAGIKINELGAIRVDEYMRTEDKNIFAVGDCAEKFSFITRIVKGLMLASTACSEARIAGMNLFGLSRLRTFS
GTIAIFSTAIGGTTFAAAGVTEQLARERGFEVVSAGFTGIDKHPGTLPETSNQYVKLIVNSENGLVLGGAVMGGQSAGEL
INVIGVIIETKMTVNELLTLQFGTHPLLTGPPTAYALIKAAEAVEMKLRHFK

Specific function: Catalyzes the four-electron reduction of molecular oxygen to water [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-III pyridine nucleotide-disulfide oxidoreductase family [H]

Homologues:

Organism=Homo sapiens, GI65787454, Length=345, Percent_Identity=26.3768115942029, Blast_Score=102, Evalue=7e-22,
Organism=Homo sapiens, GI21389617, Length=345, Percent_Identity=26.3768115942029, Blast_Score=102, Evalue=7e-22,
Organism=Homo sapiens, GI226437568, Length=345, Percent_Identity=26.3768115942029, Blast_Score=102, Evalue=8e-22,
Organism=Homo sapiens, GI91199540, Length=295, Percent_Identity=27.4576271186441, Blast_Score=81, Evalue=3e-15,
Organism=Homo sapiens, GI22202629, Length=250, Percent_Identity=28, Blast_Score=74, Evalue=3e-13,
Organism=Homo sapiens, GI4757732, Length=250, Percent_Identity=28, Blast_Score=74, Evalue=4e-13,
Organism=Escherichia coli, GI1789065, Length=203, Percent_Identity=35.9605911330049, Blast_Score=110, Evalue=3e-25,
Organism=Escherichia coli, GI1786307, Length=342, Percent_Identity=28.0701754385965, Blast_Score=95, Evalue=1e-20,
Organism=Escherichia coli, GI1789915, Length=192, Percent_Identity=33.8541666666667, Blast_Score=79, Evalue=7e-16,
Organism=Escherichia coli, GI1789765, Length=348, Percent_Identity=24.7126436781609, Blast_Score=76, Evalue=6e-15,
Organism=Escherichia coli, GI1788892, Length=237, Percent_Identity=27.8481012658228, Blast_Score=73, Evalue=4e-14,
Organism=Escherichia coli, GI87082354, Length=357, Percent_Identity=26.890756302521, Blast_Score=68, Evalue=1e-12,
Organism=Escherichia coli, GI87081717, Length=341, Percent_Identity=25.5131964809384, Blast_Score=65, Evalue=7e-12,
Organism=Caenorhabditis elegans, GI17559934, Length=211, Percent_Identity=33.175355450237, Blast_Score=100, Evalue=3e-21,
Organism=Caenorhabditis elegans, GI32565766, Length=265, Percent_Identity=24.1509433962264, Blast_Score=67, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI32564386, Length=349, Percent_Identity=22.9226361031519, Blast_Score=67, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6325166, Length=331, Percent_Identity=25.3776435045317, Blast_Score=72, Evalue=2e-13,
Organism=Drosophila melanogaster, GI21358499, Length=266, Percent_Identity=25.187969924812, Blast_Score=75, Evalue=9e-14,
Organism=Drosophila melanogaster, GI24585130, Length=264, Percent_Identity=25.3787878787879, Blast_Score=74, Evalue=3e-13,
Organism=Drosophila melanogaster, GI281359715, Length=203, Percent_Identity=27.5862068965517, Blast_Score=68, Evalue=1e-11,
Organism=Drosophila melanogaster, GI281359713, Length=203, Percent_Identity=27.5862068965517, Blast_Score=68, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24639250, Length=203, Percent_Identity=27.5862068965517, Blast_Score=68, Evalue=1e-11,
Organism=Drosophila melanogaster, GI18543267, Length=203, Percent_Identity=27.5862068965517, Blast_Score=68, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24639252, Length=203, Percent_Identity=27.5862068965517, Blast_Score=68, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24639257, Length=203, Percent_Identity=27.5862068965517, Blast_Score=68, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016156
- InterPro:   IPR013027
- InterPro:   IPR004099
- InterPro:   IPR001327 [H]

Pfam domain/function: PF00070 Pyr_redox; PF07992 Pyr_redox_2; PF02852 Pyr_redox_dim [H]

EC number: =1.6.99.3 [H]

Molecular weight: Translated: 48160; Mature: 48160

Theoretical pI: Translated: 5.78; Mature: 5.78

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKQVDVLVIGGSAAGIVAATTGKAFYASKSFLIVRKEPEAVVPCGIPYIFGTLDGVHQN
CCCEEEEEEECCCCCCEEEEECCCEEEECCEEEEEECCCCEEECCCCHHHHHCHHHHHHC
IVPTAPLANADVELLIDEVVSIDREAKSATTAGGVVISWDKLVLATGSEPKTPDWLEGRD
CCCCCCCCCCCHHHHHHHHHHHCCHHCCCCCCCCEEEEECEEEEEECCCCCCCCCCCCCC
LDGVFVIPKNRDYLCRLRSRLEEPRRVAIIGGGFIGVELADELAKKGHDVTLVEILPHVL
CCCEEEEECCCHHHHHHHHHCCCCCEEEEEECCEEEHHHHHHHHHCCCCEEHHHHHHHHH
SMAFDSDLSLKAEELLVKRGVKLKTGEKLKKLAGQASVSKVILESGEEIEVDIVILATGY
HHHCCCCCCCCHHHHHHHCCCCCCCCHHHHHHHCHHHHHHHHHCCCCEEEEEEEEEEECC
APNVELARSAGIKINELGAIRVDEYMRTEDKNIFAVGDCAEKFSFITRIVKGLMLASTAC
CCCCHHHHHCCCEEECCCCEEEHHHHHCCCCCEEEECCHHHHHHHHHHHHHHHHHHHHCC
SEARIAGMNLFGLSRLRTFSGTIAIFSTAIGGTTFAAAGVTEQLARERGFEVVSAGFTGI
CCHHCCCCCHHHHHHHHHHCCCEEEEEECCCCCHHHHCCHHHHHHHHCCCEEEECCCCCC
DKHPGTLPETSNQYVKLIVNSENGLVLGGAVMGGQSAGELINVIGVIIETKMTVNELLTL
CCCCCCCCCCCCCEEEEEEECCCCEEEEEEEECCCCHHHHHHHHHHHHHCCEEHHHEEEE
QFGTHPLLTGPPTAYALIKAAEAVEMKLRHFK
EECCCCCCCCCCHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MNKQVDVLVIGGSAAGIVAATTGKAFYASKSFLIVRKEPEAVVPCGIPYIFGTLDGVHQN
CCCEEEEEEECCCCCCEEEEECCCEEEECCEEEEEECCCCEEECCCCHHHHHCHHHHHHC
IVPTAPLANADVELLIDEVVSIDREAKSATTAGGVVISWDKLVLATGSEPKTPDWLEGRD
CCCCCCCCCCCHHHHHHHHHHHCCHHCCCCCCCCEEEEECEEEEEECCCCCCCCCCCCCC
LDGVFVIPKNRDYLCRLRSRLEEPRRVAIIGGGFIGVELADELAKKGHDVTLVEILPHVL
CCCEEEEECCCHHHHHHHHHCCCCCEEEEEECCEEEHHHHHHHHHCCCCEEHHHHHHHHH
SMAFDSDLSLKAEELLVKRGVKLKTGEKLKKLAGQASVSKVILESGEEIEVDIVILATGY
HHHCCCCCCCCHHHHHHHCCCCCCCCHHHHHHHCHHHHHHHHHCCCCEEEEEEEEEEECC
APNVELARSAGIKINELGAIRVDEYMRTEDKNIFAVGDCAEKFSFITRIVKGLMLASTAC
CCCCHHHHHCCCEEECCCCEEEHHHHHCCCCCEEEECCHHHHHHHHHHHHHHHHHHHHCC
SEARIAGMNLFGLSRLRTFSGTIAIFSTAIGGTTFAAAGVTEQLARERGFEVVSAGFTGI
CCHHCCCCCHHHHHHHHHHCCCEEEEEECCCCCHHHHCCHHHHHHHHCCCEEEECCCCCC
DKHPGTLPETSNQYVKLIVNSENGLVLGGAVMGGQSAGELINVIGVIIETKMTVNELLTL
CCCCCCCCCCCCCEEEEEEECCCCEEEEEEEECCCCHHHHHHHHHHHHHCCEEHHHEEEE
QFGTHPLLTGPPTAYALIKAAEAVEMKLRHFK
EECCCCCCCCCCHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]