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The map label for this gene is gmhB

Identifier: 21674822

GI number: 21674822

Start: 1907246

End: 1907845

Strand: Reverse

Name: gmhB

Synonym: CT2011

Alternate gene names: 21674822

Gene position: 1907845-1907246 (Counterclockwise)

Preceding gene: 21674823

Following gene: 21674821

Centisome position: 88.53

GC content: 59.83

Gene sequence:

>600_bases
ATGGAGTCTGCGAAGGTGCTTTTTCTTGACCGGGACGGAACGATCAACCGCGACATTGGCCGCTATGTTTCGAGCCGCGA
GGAGTTCATCCTGATCGACCGCGCGGACGAGGCCATCGCGATTGCGCGCGAGGCGGGGTTCCGGATCGTGCTCATTACCA
ACCAGGCGGGTATCGCCCGTGGCATCGTGACACCACAGGATGTCGAAGATGTCAACGACTATCTCAACGAACTGCTGGCG
GAGCGCCAGACCTCTTTCGACCGCTGCTACTACTGCCCGGCGCATCCAAACTATCCACATCCCGAGTACGACCGCTTCAT
CGATCACCGCAAACCCTCGCCCCGCATGGTGGAGCAGGCCATCGCCGACCTGCGCGAGGAGGGCTTCGAGGTGGATCGCA
GCGCATCGTTTTTCATCGGCGACAAGCTCATTGATGTCGAGTGCGGCCAGCGGGCCGGGTTGAAAACGATACTCGTCAGA
ACCGGCCACAACGAGGAGTCGCTCTGCGAGCAGCACCAGATTTTTCCGGATCATGTCGCCGACGATCTCTACCAGGCTGT
CACCGGCTACATTTTGGGGCAGCCAACATCAAGGGACTGA

Upstream 100 bases:

>100_bases
CGCGCTCATGCTCGAATGCATGGGGCGCGATTTTTCGTGGAGCACGTCGGCGGGGCAGTATGCCGAGCTCTACCGAAATC
TGCTTGGCTGAGGTGGTGCG

Downstream 100 bases:

>100_bases
AAGGACGAAAAGGACTTCAGGGACAGCAGGGTTTGGAGAATCGGTTTCGGGGTGTTGGAAAAATAATGAGAAAGGCGCCC
GATGATTTGCCTGTATTTGC

Product: histidinol phosphatase-related protein, putative

Products: NA

Alternate protein names: D-glycero-D-manno-heptose 1,7-bisphosphate phosphatase

Number of amino acids: Translated: 199; Mature: 199

Protein sequence:

>199_residues
MESAKVLFLDRDGTINRDIGRYVSSREEFILIDRADEAIAIAREAGFRIVLITNQAGIARGIVTPQDVEDVNDYLNELLA
ERQTSFDRCYYCPAHPNYPHPEYDRFIDHRKPSPRMVEQAIADLREEGFEVDRSASFFIGDKLIDVECGQRAGLKTILVR
TGHNEESLCEQHQIFPDHVADDLYQAVTGYILGQPTSRD

Sequences:

>Translated_199_residues
MESAKVLFLDRDGTINRDIGRYVSSREEFILIDRADEAIAIAREAGFRIVLITNQAGIARGIVTPQDVEDVNDYLNELLA
ERQTSFDRCYYCPAHPNYPHPEYDRFIDHRKPSPRMVEQAIADLREEGFEVDRSASFFIGDKLIDVECGQRAGLKTILVR
TGHNEESLCEQHQIFPDHVADDLYQAVTGYILGQPTSRD
>Mature_199_residues
MESAKVLFLDRDGTINRDIGRYVSSREEFILIDRADEAIAIAREAGFRIVLITNQAGIARGIVTPQDVEDVNDYLNELLA
ERQTSFDRCYYCPAHPNYPHPEYDRFIDHRKPSPRMVEQAIADLREEGFEVDRSASFFIGDKLIDVECGQRAGLKTILVR
TGHNEESLCEQHQIFPDHVADDLYQAVTGYILGQPTSRD

Specific function: Converts the D-glycero-D-manno-heptose 1,7-bisphosphate intermediate into D-glycero-D-manno-heptose 1-phosphate by removing the phosphate group at the C-7 position

COG id: COG0241

COG function: function code E; Histidinol phosphatase and related phosphatases

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the gmhB family

Homologues:

Organism=Escherichia coli, GI1786399, Length=162, Percent_Identity=39.5061728395062, Blast_Score=113, Evalue=8e-27,
Organism=Escherichia coli, GI87082027, Length=164, Percent_Identity=26.219512195122, Blast_Score=61, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): GMHB_CHLTE (Q8KAY7)

Other databases:

- EMBL:   AE006470
- RefSeq:   NP_662887.1
- ProteinModelPortal:   Q8KAY7
- SMR:   Q8KAY7
- GeneID:   1007550
- GenomeReviews:   AE006470_GR
- KEGG:   cte:CT2011
- NMPDR:   fig|194439.1.peg.1981
- TIGR:   CT2011
- HOGENOM:   HBG613347
- OMA:   RAGCRTV
- ProtClustDB:   CLSK638039
- BioCyc:   CTEP194439:CT_2011-MONOMER
- GO:   GO:0005737
- InterPro:   IPR023214
- InterPro:   IPR006549
- InterPro:   IPR006543
- InterPro:   IPR013954
- Gene3D:   G3DSA:3.40.50.1000
- TIGRFAMs:   TIGR01662
- TIGRFAMs:   TIGR01656

Pfam domain/function: PF08645 PNK3P; SSF56784 SSF56784

EC number: NA

Molecular weight: Translated: 22676; Mature: 22676

Theoretical pI: Translated: 4.55; Mature: 4.55

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MESAKVLFLDRDGTINRDIGRYVSSREEFILIDRADEAIAIAREAGFRIVLITNQAGIAR
CCCCEEEEEECCCCCCHHHHHHHCCCCCEEEEECCCCHHHHHHCCCEEEEEEECCCCCCC
GIVTPQDVEDVNDYLNELLAERQTSFDRCYYCPAHPNYPHPEYDRFIDHRKPSPRMVEQA
CCCCCCHHHHHHHHHHHHHHHHHCCCCCEEECCCCCCCCCCHHHHHHHCCCCCHHHHHHH
IADLREEGFEVDRSASFFIGDKLIDVECGQRAGLKTILVRTGHNEESLCEQHQIFPDHVA
HHHHHHHCCCCCCCCEEEECCEEEEECCCCCCCCEEEEEECCCCHHHHHHHHCCCHHHHH
DDLYQAVTGYILGQPTSRD
HHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MESAKVLFLDRDGTINRDIGRYVSSREEFILIDRADEAIAIAREAGFRIVLITNQAGIAR
CCCCEEEEEECCCCCCHHHHHHHCCCCCEEEEECCCCHHHHHHCCCEEEEEEECCCCCCC
GIVTPQDVEDVNDYLNELLAERQTSFDRCYYCPAHPNYPHPEYDRFIDHRKPSPRMVEQA
CCCCCCHHHHHHHHHHHHHHHHHCCCCCEEECCCCCCCCCCHHHHHHHCCCCCHHHHHHH
IADLREEGFEVDRSASFFIGDKLIDVECGQRAGLKTILVRTGHNEESLCEQHQIFPDHVA
HHHHHHHCCCCCCCCEEEECCEEEEECCCCCCCCEEEEEECCCCHHHHHHHHCCCHHHHH
DDLYQAVTGYILGQPTSRD
HHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12093901