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The map label for this gene is glcK [H]

Identifier: 21674818

GI number: 21674818

Start: 1901527

End: 1902537

Strand: Reverse

Name: glcK [H]

Synonym: CT2007

Alternate gene names: 21674818

Gene position: 1902537-1901527 (Counterclockwise)

Preceding gene: 21674819

Following gene: 21674817

Centisome position: 88.29

GC content: 65.68

Gene sequence:

>1011_bases
ATGCCATCATGGGGGCTAGGCATCGATCTCGGCGGGACGAACATCAAGATAGCGGTCGTCGATGAGTTGAAAGGGATTCT
CTTCGAGGATACCCAGCCGACCGATGTACCTTCCGGTCCCGATGGCGTCGTGCGGCAACTGGCGTTCATGGCCAGCGAAC
TCTACCAGCGCGCCACGGAAACGCTCGATGCCGGCGAGTTCGCCGGAATCGGCCTCGGTGCTCCGGGCGCGGTCGATGCC
GAGAAGGGCACCCTCTCCTATCCGCCGAACCTGCCCGGCTGGGGGCGCGTGGCTTTGCGCGACGAGCTCCGGCTCCGCCT
CGAAGAGGCGCACAGTCTTTCGTCGCCGGTCATTATCGAGAACGACGCCAACGCAGCCGCCTACGGCGAGGCGATCTTCG
GCGGCGGCAACGCCTTCCGCGACTTCATGCTCGTGACGCTCGGCACCGGCGTGGGCGGCGGCATCATTCTCGATCGCAAG
CTCTATCGCGGCCCGACCGGCACGGCGGGGGAGATCGGCTTCATGATCGTCGATTTCGAGGGCGAAAGCGTTCACGCGGG
CATCCGGGGCACCATCGAAGGGTTGATCGGCAAGGAGCGCATCGTCGAAATGGCGTGCAGCGAACAGATCGGGGCGGAGC
GGTCGCCGCGCCTCGCGGAGCTGTGCAACCGCGATTTTTCCCGCCTCTCTCCCCGCCACCTCGAACAGGCGGCCCGGGAG
GGGGACGCCGCCGCCCTGCGCACCTGGGAGCGGATCGGCACCATTCTCGGTGTCGGGCTGGCCAACATCACCGCCCTGAT
GGATATTCGCAAGTTCGTGATCGGCGGAGGTATCGCTGCCGCTGGCGAGCTGATCTTCAAGCCGGCCATGATGCAACTGC
ATCGCTCGACCCTGCCCTCGATGCACGATGGGCTGGAGATCGTTCCAGCCCGGCTCGGCAACAAGGCCGGGATCTACGGC
GCGGCAGCGCTCTGTTTCAACGCCGCAAAACCTCCCGCAAGCGATGCTTGA

Upstream 100 bases:

>100_bases
TCCGCAAACGCCGGAGGTGGTTGAAATCCTCGACTTCTTCGCCTCGGGAGTGTACAATCGGAAGTTTCTCAAGCCCTTCA
ATTCATAAGCAGTGACGGAT

Downstream 100 bases:

>100_bases
CGGACTGGTGCATCTGCTCTTTCCCGAGGTCTGCATTCTCTGCCAGAAGCCGCTCGGTGAGGGCGAGGAGCACATCTGCG
CCGGATGCTTCAATGATTTC

Product: glucokinase, putative

Products: NA

Alternate protein names: Glucose kinase [H]

Number of amino acids: Translated: 336; Mature: 335

Protein sequence:

>336_residues
MPSWGLGIDLGGTNIKIAVVDELKGILFEDTQPTDVPSGPDGVVRQLAFMASELYQRATETLDAGEFAGIGLGAPGAVDA
EKGTLSYPPNLPGWGRVALRDELRLRLEEAHSLSSPVIIENDANAAAYGEAIFGGGNAFRDFMLVTLGTGVGGGIILDRK
LYRGPTGTAGEIGFMIVDFEGESVHAGIRGTIEGLIGKERIVEMACSEQIGAERSPRLAELCNRDFSRLSPRHLEQAARE
GDAAALRTWERIGTILGVGLANITALMDIRKFVIGGGIAAAGELIFKPAMMQLHRSTLPSMHDGLEIVPARLGNKAGIYG
AAALCFNAAKPPASDA

Sequences:

>Translated_336_residues
MPSWGLGIDLGGTNIKIAVVDELKGILFEDTQPTDVPSGPDGVVRQLAFMASELYQRATETLDAGEFAGIGLGAPGAVDA
EKGTLSYPPNLPGWGRVALRDELRLRLEEAHSLSSPVIIENDANAAAYGEAIFGGGNAFRDFMLVTLGTGVGGGIILDRK
LYRGPTGTAGEIGFMIVDFEGESVHAGIRGTIEGLIGKERIVEMACSEQIGAERSPRLAELCNRDFSRLSPRHLEQAARE
GDAAALRTWERIGTILGVGLANITALMDIRKFVIGGGIAAAGELIFKPAMMQLHRSTLPSMHDGLEIVPARLGNKAGIYG
AAALCFNAAKPPASDA
>Mature_335_residues
PSWGLGIDLGGTNIKIAVVDELKGILFEDTQPTDVPSGPDGVVRQLAFMASELYQRATETLDAGEFAGIGLGAPGAVDAE
KGTLSYPPNLPGWGRVALRDELRLRLEEAHSLSSPVIIENDANAAAYGEAIFGGGNAFRDFMLVTLGTGVGGGIILDRKL
YRGPTGTAGEIGFMIVDFEGESVHAGIRGTIEGLIGKERIVEMACSEQIGAERSPRLAELCNRDFSRLSPRHLEQAAREG
DAAALRTWERIGTILGVGLANITALMDIRKFVIGGGIAAAGELIFKPAMMQLHRSTLPSMHDGLEIVPARLGNKAGIYGA
AALCFNAAKPPASDA

Specific function: Acts As A Repressor Of The Nagebacd Operon And Acts Both As An Activator And A Repressor For The Transcription Of The Glmsu Operon. [C]

COG id: COG1940

COG function: function code KG; Transcriptional regulator/sugar kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ROK (nagC/xylR) family [H]

Homologues:

Organism=Homo sapiens, GI298566325, Length=301, Percent_Identity=27.906976744186, Blast_Score=81, Evalue=1e-15,
Organism=Homo sapiens, GI298566315, Length=301, Percent_Identity=27.906976744186, Blast_Score=81, Evalue=1e-15,
Organism=Homo sapiens, GI4885285, Length=301, Percent_Identity=27.906976744186, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI190014632, Length=301, Percent_Identity=27.906976744186, Blast_Score=80, Evalue=2e-15,
Organism=Escherichia coli, GI1786891, Length=332, Percent_Identity=25.9036144578313, Blast_Score=82, Evalue=6e-17,
Organism=Escherichia coli, GI1787363, Length=332, Percent_Identity=28.6144578313253, Blast_Score=82, Evalue=7e-17,
Organism=Escherichia coli, GI1787878, Length=270, Percent_Identity=25.5555555555556, Blast_Score=79, Evalue=4e-16,
Organism=Escherichia coli, GI87081733, Length=324, Percent_Identity=25.3086419753086, Blast_Score=63, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000600
- InterPro:   IPR004654 [H]

Pfam domain/function: PF00480 ROK [H]

EC number: =2.7.1.2 [H]

Molecular weight: Translated: 35364; Mature: 35233

Theoretical pI: Translated: 4.80; Mature: 4.80

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPSWGLGIDLGGTNIKIAVVDELKGILFEDTQPTDVPSGPDGVVRQLAFMASELYQRATE
CCCCCCEEEECCCEEEEEECCCCCCEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
TLDAGEFAGIGLGAPGAVDAEKGTLSYPPNLPGWGRVALRDELRLRLEEAHSLSSPVIIE
HCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEHHHHHHHHHHHHCCCCCEEEE
NDANAAAYGEAIFGGGNAFRDFMLVTLGTGVGGGIILDRKLYRGPTGTAGEIGFMIVDFE
CCCCCHHHCCEEECCCHHHHHHHHEEECCCCCCCEEECCHHHCCCCCCCCCEEEEEEEEC
GESVHAGIRGTIEGLIGKERIVEMACSEQIGAERSPRLAELCNRDFSRLSPRHLEQAARE
CCEEECCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHCCHHHHCCHHHHHHHHHC
GDAAALRTWERIGTILGVGLANITALMDIRKFVIGGGIAAAGELIFKPAMMQLHRSTLPS
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCC
MHDGLEIVPARLGNKAGIYGAAALCFNAAKPPASDA
HHCCCCHHHHHCCCCCCHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure 
PSWGLGIDLGGTNIKIAVVDELKGILFEDTQPTDVPSGPDGVVRQLAFMASELYQRATE
CCCCCEEEECCCEEEEEECCCCCCEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
TLDAGEFAGIGLGAPGAVDAEKGTLSYPPNLPGWGRVALRDELRLRLEEAHSLSSPVIIE
HCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEHHHHHHHHHHHHCCCCCEEEE
NDANAAAYGEAIFGGGNAFRDFMLVTLGTGVGGGIILDRKLYRGPTGTAGEIGFMIVDFE
CCCCCHHHCCEEECCCHHHHHHHHEEECCCCCCCEEECCHHHCCCCCCCCCEEEEEEEEC
GESVHAGIRGTIEGLIGKERIVEMACSEQIGAERSPRLAELCNRDFSRLSPRHLEQAARE
CCEEECCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHCCHHHHCCHHHHHHHHHC
GDAAALRTWERIGTILGVGLANITALMDIRKFVIGGGIAAAGELIFKPAMMQLHRSTLPS
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCC
MHDGLEIVPARLGNKAGIYGAAALCFNAAKPPASDA
HHCCCCHHHHHCCCCCCHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11058132 [H]