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The map label for this gene is 21674757

Identifier: 21674757

GI number: 21674757

Start: 1836574

End: 1837791

Strand: Reverse

Name: 21674757

Synonym: CT1945

Alternate gene names: NA

Gene position: 1837791-1836574 (Counterclockwise)

Preceding gene: 21674761

Following gene: 21674755

Centisome position: 85.28

GC content: 51.72

Gene sequence:

>1218_bases
ATGCGAATATTAACTTTTACTGGCAAGGGTGGTGTGGGCAAGACAAGCGTCTCGGCCGCCACGGCAGTTCGTCTTTCCGA
AATGGGTCACCGCACCCTCGTGCTTTCCACCGACCCCGCCCACAGTCTTTCCGATTCGTTCAACATTCAGCTTGGCGCCG
AGCCGACCAAGATCAAGGAAAACCTTCACGCCATCGAGGTGAACCCCTATGTTGACCTCAAGCAGAACTGGCATTCTGTA
CAGAAGTACTATACCCGTATTTTCATGGCCCAGGGCGTCTCCGGCGTCATGGCCGATGAAATGACGATTCTTCCCGGCAT
GGAGGAGCTTTTTTCTCTGCTCCGCATCAAACGCTACAAATCCGCCGGTCTCTACGATGCGCTTGTGCTTGATACGGCGC
CGACCGGTGAAACCCTTCGCCTGCTCTCATTGCCCGATACTCTTTCGTGGGGCATGAAGGCGGTCAAAAACGTCAACAAA
TACATTGTCCGTCCGCTCAGCAAACCGCTTTCCAAGATGTCGGACAAGATTGCTTACTACATTCCTCCGGAAGACGCCAT
CGAGTCGGTTGATCAGGTGTTCGACGAGCTCGAAGATATCCGCGAGATTCTGACTGACAACGTCAAGTCAACCGTCAGAT
TGGTGATGAATGCTGAGAAGATGTCAATCAAGGAGACCATGCGCGCCTTGACCTACCTGAACCTCTATGGTTTCAAGGTC
GATATGGTACTGGTCAACAAACTTCTCGACGCGCAAGAGAACAGCGGTTACCTTGAAAAGTGGAAAGGTATCCAACAAAA
ATATCTCGGTGAGATCGAAGAGGGATTCTCTCCGCTGCCAGTCAAAAAGCTGAAAATGTATGATCAGGAGATCGTTGGCG
TGAAGTCGCTGGAGGTCTTCGCGCATGACATCTACGGCGATACCGATCCGTCCGGTATGATGTATGACGAACCGCCGATC
AAGTTTGTCCGCCAAGGAGACGTGTATGAAGTTCAGCTCAAGCTTATGTTTGCCAACCCTGTCGATATCGACGTGTGGGT
GACTGGTGATGAGTTGTTTGTGCAGATCGGTAACCAGCGTAAGATCATCACTCTGCCGGTCAGTCTGACTGGTCTGGAAC
CCGGCGATGCCGTTTTCAAGGACAAGTGGCTCCATATTCCGTTTGATCTCGAAAAGCAGGGGCAGCATCACCGCACGAGG
GAGTATAACAAGGCATAA

Upstream 100 bases:

>100_bases
GGCTCTGCATGTGCGATGTGGTGAATGTTCCTTTGCAGAATGATGTGAGAAGTATATCTTAACGATCTTGGCTGTACAAT
AAACTTCCAATGCCTGGTTC

Downstream 100 bases:

>100_bases
CGCGTGGCTTGGTTCTGTTTGAGCATGGCTGATTTTTTTATTAGGTTTAAGTAGATGTAAATTTCACCATAAAACCAGTA
ACCGGTGGCTGCACCGGCCG

Product: ArsA ATPase family protein

Products: NA

Alternate protein names: Arsenical resistance ATPase; Arsenite-translocating ATPase; Arsenite-transporting ATPase

Number of amino acids: Translated: 405; Mature: 405

Protein sequence:

>405_residues
MRILTFTGKGGVGKTSVSAATAVRLSEMGHRTLVLSTDPAHSLSDSFNIQLGAEPTKIKENLHAIEVNPYVDLKQNWHSV
QKYYTRIFMAQGVSGVMADEMTILPGMEELFSLLRIKRYKSAGLYDALVLDTAPTGETLRLLSLPDTLSWGMKAVKNVNK
YIVRPLSKPLSKMSDKIAYYIPPEDAIESVDQVFDELEDIREILTDNVKSTVRLVMNAEKMSIKETMRALTYLNLYGFKV
DMVLVNKLLDAQENSGYLEKWKGIQQKYLGEIEEGFSPLPVKKLKMYDQEIVGVKSLEVFAHDIYGDTDPSGMMYDEPPI
KFVRQGDVYEVQLKLMFANPVDIDVWVTGDELFVQIGNQRKIITLPVSLTGLEPGDAVFKDKWLHIPFDLEKQGQHHRTR
EYNKA

Sequences:

>Translated_405_residues
MRILTFTGKGGVGKTSVSAATAVRLSEMGHRTLVLSTDPAHSLSDSFNIQLGAEPTKIKENLHAIEVNPYVDLKQNWHSV
QKYYTRIFMAQGVSGVMADEMTILPGMEELFSLLRIKRYKSAGLYDALVLDTAPTGETLRLLSLPDTLSWGMKAVKNVNK
YIVRPLSKPLSKMSDKIAYYIPPEDAIESVDQVFDELEDIREILTDNVKSTVRLVMNAEKMSIKETMRALTYLNLYGFKV
DMVLVNKLLDAQENSGYLEKWKGIQQKYLGEIEEGFSPLPVKKLKMYDQEIVGVKSLEVFAHDIYGDTDPSGMMYDEPPI
KFVRQGDVYEVQLKLMFANPVDIDVWVTGDELFVQIGNQRKIITLPVSLTGLEPGDAVFKDKWLHIPFDLEKQGQHHRTR
EYNKA
>Mature_405_residues
MRILTFTGKGGVGKTSVSAATAVRLSEMGHRTLVLSTDPAHSLSDSFNIQLGAEPTKIKENLHAIEVNPYVDLKQNWHSV
QKYYTRIFMAQGVSGVMADEMTILPGMEELFSLLRIKRYKSAGLYDALVLDTAPTGETLRLLSLPDTLSWGMKAVKNVNK
YIVRPLSKPLSKMSDKIAYYIPPEDAIESVDQVFDELEDIREILTDNVKSTVRLVMNAEKMSIKETMRALTYLNLYGFKV
DMVLVNKLLDAQENSGYLEKWKGIQQKYLGEIEEGFSPLPVKKLKMYDQEIVGVKSLEVFAHDIYGDTDPSGMMYDEPPI
KFVRQGDVYEVQLKLMFANPVDIDVWVTGDELFVQIGNQRKIITLPVSLTGLEPGDAVFKDKWLHIPFDLEKQGQHHRTR
EYNKA

Specific function: Anion-transporting ATPase. Catalyzes the extrusion of arsenite

COG id: COG0003

COG function: function code P; Oxyanion-translocating ATPase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the arsA ATPase family

Homologues:

Organism=Homo sapiens, GI50428938, Length=290, Percent_Identity=27.2413793103448, Blast_Score=112, Evalue=7e-25,
Organism=Caenorhabditis elegans, GI17557003, Length=303, Percent_Identity=26.4026402640264, Blast_Score=87, Evalue=1e-17,
Organism=Saccharomyces cerevisiae, GI6320103, Length=317, Percent_Identity=28.391167192429, Blast_Score=115, Evalue=2e-26,
Organism=Drosophila melanogaster, GI24586297, Length=304, Percent_Identity=28.2894736842105, Blast_Score=120, Evalue=2e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ARSA_CHLTE (Q46366)

Other databases:

- EMBL:   AE006470
- EMBL:   U09866
- RefSeq:   NP_662822.1
- ProteinModelPortal:   Q46366
- GeneID:   1008253
- GenomeReviews:   AE006470_GR
- KEGG:   cte:CT1945
- NMPDR:   fig|194439.1.peg.1916
- TIGR:   CT1945
- HOGENOM:   HBG564762
- OMA:   YIPPEDA
- ProtClustDB:   CLSK903970
- BioCyc:   CTEP194439:CT_1945-MONOMER
- BRENDA:   3.6.3.16
- InterPro:   IPR003348
- TIGRFAMs:   TIGR00345

Pfam domain/function: NA

EC number: =3.6.3.16

Molecular weight: Translated: 45849; Mature: 45849

Theoretical pI: Translated: 5.92; Mature: 5.92

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRILTFTGKGGVGKTSVSAATAVRLSEMGHRTLVLSTDPAHSLSDSFNIQLGAEPTKIKE
CEEEEEECCCCCCCCHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCEEEECCCCHHHHC
NLHAIEVNPYVDLKQNWHSVQKYYTRIFMAQGVSGVMADEMTILPGMEELFSLLRIKRYK
CCEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHCCEEECCCHHHHHHHHHHHHHH
SAGLYDALVLDTAPTGETLRLLSLPDTLSWGMKAVKNVNKYIVRPLSKPLSKMSDKIAYY
CCCCEEEEEEECCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEE
IPPEDAIESVDQVFDELEDIREILTDNVKSTVRLVMNAEKMSIKETMRALTYLNLYGFKV
ECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEE
DMVLVNKLLDAQENSGYLEKWKGIQQKYLGEIEEGFSPLPVKKLKMYDQEIVGVKSLEVF
HHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCHHHHHHH
AHDIYGDTDPSGMMYDEPPIKFVRQGDVYEVQLKLMFANPVDIDVWVTGDELFVQIGNQR
HHHHCCCCCCCCCEECCCCHHHEECCCEEEEEEEEEEECCCEEEEEEECCEEEEEECCCC
KIITLPVSLTGLEPGDAVFKDKWLHIPFDLEKQGQHHRTREYNKA
EEEEEEEEEECCCCCCCHHCCCEEECCCCCCCCCCCHHCCCCCCC
>Mature Secondary Structure
MRILTFTGKGGVGKTSVSAATAVRLSEMGHRTLVLSTDPAHSLSDSFNIQLGAEPTKIKE
CEEEEEECCCCCCCCHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCEEEECCCCHHHHC
NLHAIEVNPYVDLKQNWHSVQKYYTRIFMAQGVSGVMADEMTILPGMEELFSLLRIKRYK
CCEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHCCEEECCCHHHHHHHHHHHHHH
SAGLYDALVLDTAPTGETLRLLSLPDTLSWGMKAVKNVNKYIVRPLSKPLSKMSDKIAYY
CCCCEEEEEEECCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEE
IPPEDAIESVDQVFDELEDIREILTDNVKSTVRLVMNAEKMSIKETMRALTYLNLYGFKV
ECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEE
DMVLVNKLLDAQENSGYLEKWKGIQQKYLGEIEEGFSPLPVKKLKMYDQEIVGVKSLEVF
HHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCHHHHHHH
AHDIYGDTDPSGMMYDEPPIKFVRQGDVYEVQLKLMFANPVDIDVWVTGDELFVQIGNQR
HHHHCCCCCCCCCEECCCCHHHEECCCEEEEEEEEEEECCCEEEEEEECCEEEEEECCCC
KIITLPVSLTGLEPGDAVFKDKWLHIPFDLEKQGQHHRTREYNKA
EEEEEEEEEECCCCCCCHHCCCEEECCCCCCCCCCCHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12093901