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The map label for this gene is 21674751

Identifier: 21674751

GI number: 21674751

Start: 1832114

End: 1833268

Strand: Reverse

Name: 21674751

Synonym: CT1939

Alternate gene names: NA

Gene position: 1833268-1832114 (Counterclockwise)

Preceding gene: 21674752

Following gene: 21674748

Centisome position: 85.07

GC content: 54.46

Gene sequence:

>1155_bases
ATGAGAATCATCCTTTATTTGGGCAAAGGTGGAGTGGGTAAGACCACCGTATCTGCTTCCACCGCGACGGCGATCGCTCG
CAGTGGCAAGCGCGTGCTGATCATGAGCACTGATGTCGCCCATAGCCTGGCCGATGCGTTTGGCGTCGAGTTGAGTTCGA
CTCCTGTGGAGGTCGAGAAAAATCTCTTTGCCATGGAGGTGAACATTCTTGCTGAAATCAGGGAAAACTGGACCGAACTG
TACTCCTATTTCTCCTCGATTCTCATGCACGACGGTACAAATGAAATCGTCGCCGAAGAGCTGGCCATCGTGCCCGGCAT
GGAGGAGATGATCAGCCTTCGCTACATCTGGAAAGCCGCAAAATCCGGGAAGTACGACGCCGTCGTGGTCGATGCCGCTC
CGACCGGCGAAACGATGCGCCTGCTCGGTATGCCCGAGTCTTACGGCTGGTACTCCGAGAAGATCGGCGGCTGGCACTCC
AAGGCGATCGGCTTTGCCGCGCCGCTTCTGAGCCGCTTCATGCCGAAGAAGAACATCTTCAAGCTCATGCCCGAGGTCAA
CGAGCACATGAAGGAGCTGCACGGCATGTTGCAGGACAAGAGCATCACCACTTTCAGGGTGGTGCTTAATCCGGAGAACA
TGGTCATCAAAGAAGCTTTGCGCGTTCAGACCTATCTCAACCTTTTTGGGTACAAGCTCGACGCGGCGGTTGTCAACAAG
GTGCTGCCTTCGAACTCTAGCGATCCCTACCTCCAGGCTCTGATCGATCAACAGGCAAAGTATCTCCGCGTGATCGACAA
CTGCTTCTATCCGGTGCCGATTTTCAGGGCGATGCAGTCCTCCAAGGAGGTTATCAGTACTGACAGGCTGTATGACCTGA
GCCAGGAGCTTTTCAGTGGCCGTAATCCGATGGAGGTGCTCTACAGCAACGACAAGACCCAGACGCTTGAAAAGATCAAC
GGCAAGTACGTACTGAGCCTCTATCTGCCGAACGTTGAGGTGGACAAGCTCGCGGTGAACATCAAGGGTGACGAGCTGCT
CGTCGATATCAACAACTTCCGTAAGAGCATCGTGCTGCCCAACGTGCTGGTAGGCCGCAAAACCGAAGGTGCCGATTTCG
AACAGGGTACACTGAATATCACTTTCGCGAACTGA

Upstream 100 bases:

>100_bases
GTCACGGCAAACGGCGCGGCAGATAAGTCTGACGGTGATAAGCCTGAGGGAAGCAAGCATTCAGTTTACAGTCAAGTTTA
CACTATAGTTTTTCAACACC

Downstream 100 bases:

>100_bases
GCGGAAAGCGAGGTTTTAATATAAAAGCGGGCTACTTCACGGTGGTCCGCTTTTTTTATTGGAAGATCAGCCGGGTCAGT
CAGGTCGGCCTGATCTTCAA

Product: ArsA ATPase family protein

Products: NA

Alternate protein names: Arsenical resistance ATPase; Arsenite-translocating ATPase; Arsenite-transporting ATPase [H]

Number of amino acids: Translated: 384; Mature: 384

Protein sequence:

>384_residues
MRIILYLGKGGVGKTTVSASTATAIARSGKRVLIMSTDVAHSLADAFGVELSSTPVEVEKNLFAMEVNILAEIRENWTEL
YSYFSSILMHDGTNEIVAEELAIVPGMEEMISLRYIWKAAKSGKYDAVVVDAAPTGETMRLLGMPESYGWYSEKIGGWHS
KAIGFAAPLLSRFMPKKNIFKLMPEVNEHMKELHGMLQDKSITTFRVVLNPENMVIKEALRVQTYLNLFGYKLDAAVVNK
VLPSNSSDPYLQALIDQQAKYLRVIDNCFYPVPIFRAMQSSKEVISTDRLYDLSQELFSGRNPMEVLYSNDKTQTLEKIN
GKYVLSLYLPNVEVDKLAVNIKGDELLVDINNFRKSIVLPNVLVGRKTEGADFEQGTLNITFAN

Sequences:

>Translated_384_residues
MRIILYLGKGGVGKTTVSASTATAIARSGKRVLIMSTDVAHSLADAFGVELSSTPVEVEKNLFAMEVNILAEIRENWTEL
YSYFSSILMHDGTNEIVAEELAIVPGMEEMISLRYIWKAAKSGKYDAVVVDAAPTGETMRLLGMPESYGWYSEKIGGWHS
KAIGFAAPLLSRFMPKKNIFKLMPEVNEHMKELHGMLQDKSITTFRVVLNPENMVIKEALRVQTYLNLFGYKLDAAVVNK
VLPSNSSDPYLQALIDQQAKYLRVIDNCFYPVPIFRAMQSSKEVISTDRLYDLSQELFSGRNPMEVLYSNDKTQTLEKIN
GKYVLSLYLPNVEVDKLAVNIKGDELLVDINNFRKSIVLPNVLVGRKTEGADFEQGTLNITFAN
>Mature_384_residues
MRIILYLGKGGVGKTTVSASTATAIARSGKRVLIMSTDVAHSLADAFGVELSSTPVEVEKNLFAMEVNILAEIRENWTEL
YSYFSSILMHDGTNEIVAEELAIVPGMEEMISLRYIWKAAKSGKYDAVVVDAAPTGETMRLLGMPESYGWYSEKIGGWHS
KAIGFAAPLLSRFMPKKNIFKLMPEVNEHMKELHGMLQDKSITTFRVVLNPENMVIKEALRVQTYLNLFGYKLDAAVVNK
VLPSNSSDPYLQALIDQQAKYLRVIDNCFYPVPIFRAMQSSKEVISTDRLYDLSQELFSGRNPMEVLYSNDKTQTLEKIN
GKYVLSLYLPNVEVDKLAVNIKGDELLVDINNFRKSIVLPNVLVGRKTEGADFEQGTLNITFAN

Specific function: Anion-transporting ATPase. Catalyzes the extrusion of arsenite [H]

COG id: COG0003

COG function: function code P; Oxyanion-translocating ATPase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the arsA ATPase family [H]

Homologues:

Organism=Homo sapiens, GI50428938, Length=299, Percent_Identity=25.752508361204, Blast_Score=79, Evalue=7e-15,
Organism=Caenorhabditis elegans, GI17557003, Length=280, Percent_Identity=28.2142857142857, Blast_Score=81, Evalue=8e-16,
Organism=Saccharomyces cerevisiae, GI6320103, Length=315, Percent_Identity=25.0793650793651, Blast_Score=90, Evalue=5e-19,
Organism=Drosophila melanogaster, GI24586297, Length=307, Percent_Identity=28.3387622149837, Blast_Score=92, Evalue=6e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003348
- InterPro:   IPR008978 [H]

Pfam domain/function: NA

EC number: =3.6.3.16 [H]

Molecular weight: Translated: 42960; Mature: 42960

Theoretical pI: Translated: 6.09; Mature: 6.09

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRIILYLGKGGVGKTTVSASTATAIARSGKRVLIMSTDVAHSLADAFGVELSSTPVEVEK
CEEEEEECCCCCCCEEECCHHHHHHHHCCCEEEEEECHHHHHHHHHHCCCCCCCCHHHCC
NLFAMEVNILAEIRENWTELYSYFSSILMHDGTNEIVAEELAIVPGMEEMISLRYIWKAA
CEEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHH
KSGKYDAVVVDAAPTGETMRLLGMPESYGWYSEKIGGWHSKAIGFAAPLLSRFMPKKNIF
CCCCCCEEEEECCCCCCCEEEEECCCCCCCHHHHCCCCHHHHHHHHHHHHHHHCCHHHHH
KLMPEVNEHMKELHGMLQDKSITTFRVVLNPENMVIKEALRVQTYLNLFGYKLDAAVVNK
HHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHCCCHHHHHHHH
VLPSNSSDPYLQALIDQQAKYLRVIDNCFYPVPIFRAMQSSKEVISTDRLYDLSQELFSG
HCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCC
RNPMEVLYSNDKTQTLEKINGKYVLSLYLPNVEVDKLAVNIKGDELLVDINNFRKSIVLP
CCCEEEEECCCHHHHHHHCCCEEEEEEEECCCEEEEEEEEECCCEEEEEHHHHHHHHCCC
NVLVGRKTEGADFEQGTLNITFAN
CCEECCCCCCCCCCCCEEEEEECC
>Mature Secondary Structure
MRIILYLGKGGVGKTTVSASTATAIARSGKRVLIMSTDVAHSLADAFGVELSSTPVEVEK
CEEEEEECCCCCCCEEECCHHHHHHHHCCCEEEEEECHHHHHHHHHHCCCCCCCCHHHCC
NLFAMEVNILAEIRENWTELYSYFSSILMHDGTNEIVAEELAIVPGMEEMISLRYIWKAA
CEEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHH
KSGKYDAVVVDAAPTGETMRLLGMPESYGWYSEKIGGWHSKAIGFAAPLLSRFMPKKNIF
CCCCCCEEEEECCCCCCCEEEEECCCCCCCHHHHCCCCHHHHHHHHHHHHHHHCCHHHHH
KLMPEVNEHMKELHGMLQDKSITTFRVVLNPENMVIKEALRVQTYLNLFGYKLDAAVVNK
HHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHCCCHHHHHHHH
VLPSNSSDPYLQALIDQQAKYLRVIDNCFYPVPIFRAMQSSKEVISTDRLYDLSQELFSG
HCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCC
RNPMEVLYSNDKTQTLEKINGKYVLSLYLPNVEVDKLAVNIKGDELLVDINNFRKSIVLP
CCCEEEEECCCHHHHHHHCCCEEEEEEEECCCEEEEEEEEECCCEEEEEHHHHHHHHCCC
NVLVGRKTEGADFEQGTLNITFAN
CCEECCCCCCCCCCCCEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8590279; 8905231 [H]