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The map label for this gene is asd [H]

Identifier: 21674740

GI number: 21674740

Start: 1822441

End: 1823457

Strand: Reverse

Name: asd [H]

Synonym: CT1928

Alternate gene names: 21674740

Gene position: 1823457-1822441 (Counterclockwise)

Preceding gene: 21674741

Following gene: 21674739

Centisome position: 84.62

GC content: 61.46

Gene sequence:

>1017_bases
ATGAGCAGTGAAGCAGGCTATCGAGTAGCCGTTCTTGGCGCAACCGGCCTGGTTGGCAGAACCATGATCAAGGTGCTCGA
AGAGCGCAATTTTCCGGTCAGCGAGCTGGTGCCACTCGCCTCTCCGCGGAGCCGGGGCGAAGTGATCACCTTCAATGGGC
GCGAGTTCGTGACCGAAGTGCCGTCGGCGGAGATTTTCAAAGGCGTTGACATTGCGCTCTTCTCGGCTGGCGCGACGGTG
AGCAAGGAGTGGGCGCCCGTGGCCGCCGAGGCAGGCGCGATCGTGATCGACAACTCCTCGGCTTTCCGTATGGACGAGGG
AATTCCGCTTGTTGTCCCGGAGGTCAATCCTGAAACTATCTTCGACCGCGAAGGCAAGGCGGCTCCGATCATCGCCAATC
CCAACTGCTCGACCATCCAGATGGTTGTGGTGCTCAAGCCGCTCTACGACGCCTACGGCATCCGCCGCGTGGTGGTTTCG
ACCTACCAGTCGGTGACGGGCAAGGGCAAGGCCGGACGCGATGCGCTCGAAAGCGAGCTGGCGGGCAACATCCCCGACGA
GTTCACCCACTTCCACCAGATCGCCTTCAACGCCGTACCGCAGATCGACGCCTTCACCGAGAACGGCTACACCAAAGAGG
AGATGAAGATGGTTAACGAGACGAAAAAGATCATGGGTGACGACACCATCCAGGTCTCGCCGACCACCGTGCGCATTCCG
GTTTATGGCGGCCACGGAGAAGCGCTGAACGTCGAGCTGAGGAGCGATTTCGATATCGACCAGGTGCGTGCTCTGCTCGC
GGGATCACCGGGCATCGTCATGCAGGACGACCCGTCGGCGCGTCTTTACCCGATGCCGATGACCTCCTACGAGCGCGATG
AGGTGTTCGTGGGCCGTCTGCGCCCCGACTACTGGCACCCGCGCACCCTGAATCTCTGGGTCGTTGCCGACAACCTCCGC
AAAGGCGCCGCCACCAATGCCGTGCAGATTGCTGAGCTGCTGGTGGGGAATCTGTGA

Upstream 100 bases:

>100_bases
CTCGACCGCGAGGGGCTTCTGAAGGAGGGGGGTGAAAACCTGAACGATCACTCGCCCAGACTGATTCTCAATTACTAAAC
CATCATCCATTCTTACGTAT

Downstream 100 bases:

>100_bases
GGATTGATGTGTGACTGAATTTCTTGTAGGGGCGGTTCTTGTGGCCGCTCTTTTTATTTGGGAGGACAGGACGGCAAGGA
CAGCAGGGGCGGGCGTTTTT

Product: aspartate-semialdehyde dehydrogenase

Products: NA

Alternate protein names: ASA dehydrogenase; ASADH [H]

Number of amino acids: Translated: 338; Mature: 337

Protein sequence:

>338_residues
MSSEAGYRVAVLGATGLVGRTMIKVLEERNFPVSELVPLASPRSRGEVITFNGREFVTEVPSAEIFKGVDIALFSAGATV
SKEWAPVAAEAGAIVIDNSSAFRMDEGIPLVVPEVNPETIFDREGKAAPIIANPNCSTIQMVVVLKPLYDAYGIRRVVVS
TYQSVTGKGKAGRDALESELAGNIPDEFTHFHQIAFNAVPQIDAFTENGYTKEEMKMVNETKKIMGDDTIQVSPTTVRIP
VYGGHGEALNVELRSDFDIDQVRALLAGSPGIVMQDDPSARLYPMPMTSYERDEVFVGRLRPDYWHPRTLNLWVVADNLR
KGAATNAVQIAELLVGNL

Sequences:

>Translated_338_residues
MSSEAGYRVAVLGATGLVGRTMIKVLEERNFPVSELVPLASPRSRGEVITFNGREFVTEVPSAEIFKGVDIALFSAGATV
SKEWAPVAAEAGAIVIDNSSAFRMDEGIPLVVPEVNPETIFDREGKAAPIIANPNCSTIQMVVVLKPLYDAYGIRRVVVS
TYQSVTGKGKAGRDALESELAGNIPDEFTHFHQIAFNAVPQIDAFTENGYTKEEMKMVNETKKIMGDDTIQVSPTTVRIP
VYGGHGEALNVELRSDFDIDQVRALLAGSPGIVMQDDPSARLYPMPMTSYERDEVFVGRLRPDYWHPRTLNLWVVADNLR
KGAATNAVQIAELLVGNL
>Mature_337_residues
SSEAGYRVAVLGATGLVGRTMIKVLEERNFPVSELVPLASPRSRGEVITFNGREFVTEVPSAEIFKGVDIALFSAGATVS
KEWAPVAAEAGAIVIDNSSAFRMDEGIPLVVPEVNPETIFDREGKAAPIIANPNCSTIQMVVVLKPLYDAYGIRRVVVST
YQSVTGKGKAGRDALESELAGNIPDEFTHFHQIAFNAVPQIDAFTENGYTKEEMKMVNETKKIMGDDTIQVSPTTVRIPV
YGGHGEALNVELRSDFDIDQVRALLAGSPGIVMQDDPSARLYPMPMTSYERDEVFVGRLRPDYWHPRTLNLWVVADNLRK
GAATNAVQIAELLVGNL

Specific function: Unknown

COG id: COG0136

COG function: function code E; Aspartate-semialdehyde dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aspartate-semialdehyde dehydrogenase family [H]

Homologues:

Organism=Escherichia coli, GI1788658, Length=336, Percent_Identity=34.8214285714286, Blast_Score=189, Evalue=3e-49,
Organism=Escherichia coli, GI1789841, Length=360, Percent_Identity=25.2777777777778, Blast_Score=84, Evalue=1e-17,
Organism=Saccharomyces cerevisiae, GI6320362, Length=390, Percent_Identity=28.7179487179487, Blast_Score=92, Evalue=1e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000319
- InterPro:   IPR012080
- InterPro:   IPR005986
- InterPro:   IPR016040
- InterPro:   IPR000534
- InterPro:   IPR012280 [H]

Pfam domain/function: PF01118 Semialdhyde_dh; PF02774 Semialdhyde_dhC [H]

EC number: =1.2.1.11 [H]

Molecular weight: Translated: 36840; Mature: 36709

Theoretical pI: Translated: 4.68; Mature: 4.68

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSEAGYRVAVLGATGLVGRTMIKVLEERNFPVSELVPLASPRSRGEVITFNGREFVTEV
CCCCCCEEEEEEECCCHHHHHHHHHHHHCCCCHHHHCCCCCCCCCCCEEEECCHHHHHCC
PSAEIFKGVDIALFSAGATVSKEWAPVAAEAGAIVIDNSSAFRMDEGIPLVVPEVNPETI
CCHHHHCCCEEEEEECCCCCCCCCCCCCCCCCEEEEECCCCEEECCCCEEEEECCCCCCE
FDREGKAAPIIANPNCSTIQMVVVLKPLYDAYGIRRVVVSTYQSVTGKGKAGRDALESEL
ECCCCCCCCEEECCCCCEEEEEEEEHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHH
AGNIPDEFTHFHQIAFNAVPQIDAFTENGYTKEEMKMVNETKKIMGDDTIQVSPTTVRIP
CCCCCHHHHHHHHHHHHCCCCCEEECCCCCCHHHHHHHHHHHHHCCCCEEEECCCEEEEE
VYGGHGEALNVELRSDFDIDQVRALLAGSPGIVMQDDPSARLYPMPMTSYERDEVFVGRL
EECCCCCEEEEEECCCCCHHHHHHHHCCCCCEEEECCCCCEEEECCCCCCCCCCEEEECC
RPDYWHPRTLNLWVVADNLRKGAATNAVQIAELLVGNL
CCCCCCCCEEEEEEEECCCCCCCCCCHHHHHHHHHCCC
>Mature Secondary Structure 
SSEAGYRVAVLGATGLVGRTMIKVLEERNFPVSELVPLASPRSRGEVITFNGREFVTEV
CCCCCEEEEEEECCCHHHHHHHHHHHHCCCCHHHHCCCCCCCCCCCEEEECCHHHHHCC
PSAEIFKGVDIALFSAGATVSKEWAPVAAEAGAIVIDNSSAFRMDEGIPLVVPEVNPETI
CCHHHHCCCEEEEEECCCCCCCCCCCCCCCCCEEEEECCCCEEECCCCEEEEECCCCCCE
FDREGKAAPIIANPNCSTIQMVVVLKPLYDAYGIRRVVVSTYQSVTGKGKAGRDALESEL
ECCCCCCCCEEECCCCCEEEEEEEEHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHH
AGNIPDEFTHFHQIAFNAVPQIDAFTENGYTKEEMKMVNETKKIMGDDTIQVSPTTVRIP
CCCCCHHHHHHHHHHHHCCCCCEEECCCCCCHHHHHHHHHHHHHCCCCEEEECCCEEEEE
VYGGHGEALNVELRSDFDIDQVRALLAGSPGIVMQDDPSARLYPMPMTSYERDEVFVGRL
EECCCCCEEEEEECCCCCHHHHHHHHCCCCCEEEECCCCCEEEECCCCCCCCCCEEEECC
RPDYWHPRTLNLWVVADNLRKGAATNAVQIAELLVGNL
CCCCCCCCEEEEEEEECCCCCCCCCCHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9537320 [H]