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The map label for this gene is arsC [H]

Identifier: 21674541

GI number: 21674541

Start: 1635441

End: 1635875

Strand: Reverse

Name: arsC [H]

Synonym: CT1725

Alternate gene names: 21674541

Gene position: 1635875-1635441 (Counterclockwise)

Preceding gene: 21674542

Following gene: 21674540

Centisome position: 75.91

GC content: 58.16

Gene sequence:

>435_bases
ATGAAAAAATCGATACTTGTTCTCTGCACTGGCAACTCCTGCCGCAGCCAGATGGCGGAGGGATTCCTTCGTTCGTTCGA
TTCCGAACTCGACGTGTTCTCTGCAGGCACGGTTCCGGCAAGCGAGGTGCATCCGCTGGCCGTTCAGGTGATGCGGGAAA
AAGGGATCGACCTCAGCGCCAATCGCCCGAAAAAAGTGGACGAATTTCTCACCAAGCCGTTCGATTACGTCGTGACGGTC
TGCGATAGCGCCAAGGAGAGCTGCCCGCTCTTTACCGGCCAGGTCAAGCACCGCCAGCACATCGGCTTCGACGATCCGGC
GGCGGCCACCGGCAGCAGCGAAGAGGTGCTCGCCGAGTTCCGCCGGGTACGCGACGAGATCGAGCAGGAGTTTGGGAAAT
TTTATCGTGAAACCATCCGGGGAGAAAAACCATGA

Upstream 100 bases:

>100_bases
CGCAGCTCATCGCGGTTTTCGCCGGAGTGGTAGCCACGGGCATCATGCTGGTCGGTTTCGTGTTCAATGCGATTTTCTGA
TCCGCAAAAACCTATAAGTC

Downstream 100 bases:

>100_bases
GTATCTCGACAAAACAGCTCTCTTTCCTTGACCGTTATTTGACGCTCTGGATTTTTCTCGCGATGGGCATCGGCGTGCTC
TCCGGCTTTCTCTACCCGCA

Product: arsenate reductase

Products: NA

Alternate protein names: Arsenate reductase; Arsenical pump modifier; Low molecular weight protein-tyrosine-phosphatase [H]

Number of amino acids: Translated: 144; Mature: 144

Protein sequence:

>144_residues
MKKSILVLCTGNSCRSQMAEGFLRSFDSELDVFSAGTVPASEVHPLAVQVMREKGIDLSANRPKKVDEFLTKPFDYVVTV
CDSAKESCPLFTGQVKHRQHIGFDDPAAATGSSEEVLAEFRRVRDEIEQEFGKFYRETIRGEKP

Sequences:

>Translated_144_residues
MKKSILVLCTGNSCRSQMAEGFLRSFDSELDVFSAGTVPASEVHPLAVQVMREKGIDLSANRPKKVDEFLTKPFDYVVTV
CDSAKESCPLFTGQVKHRQHIGFDDPAAATGSSEEVLAEFRRVRDEIEQEFGKFYRETIRGEKP
>Mature_144_residues
MKKSILVLCTGNSCRSQMAEGFLRSFDSELDVFSAGTVPASEVHPLAVQVMREKGIDLSANRPKKVDEFLTKPFDYVVTV
CDSAKESCPLFTGQVKHRQHIGFDDPAAATGSSEEVLAEFRRVRDEIEQEFGKFYRETIRGEKP

Specific function: Reduces arsenate [As(V)] to arsenite [As(III)] and dephosphorylates tyrosine phosphorylated proteins, low-MW aryl phosphates and natural and synthetic acyl phosphates. Could switch between different functions in different circumstances [H]

COG id: COG0394

COG function: function code T; Protein-tyrosine-phosphatase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the low molecular weight phosphotyrosine protein phosphatase superfamily. ArsC family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014064
- InterPro:   IPR017867 [H]

Pfam domain/function: PF01451 LMWPc [H]

EC number: =3.1.3.48 [H]

Molecular weight: Translated: 16119; Mature: 16119

Theoretical pI: Translated: 5.74; Mature: 5.74

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.8 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
2.8 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKSILVLCTGNSCRSQMAEGFLRSFDSELDVFSAGTVPASEVHPLAVQVMREKGIDLSA
CCCCEEEEECCCHHHHHHHHHHHHHHCCCCCHHCCCCCCCHHHHHHHHHHHHHCCCCCCC
NRPKKVDEFLTKPFDYVVTVCDSAKESCPLFTGQVKHRQHIGFDDPAAATGSSEEVLAEF
CCCHHHHHHHHCCHHHHHHHHHHHHHCCCCCCCCHHHHHCCCCCCCCCCCCCHHHHHHHH
RRVRDEIEQEFGKFYRETIRGEKP
HHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MKKSILVLCTGNSCRSQMAEGFLRSFDSELDVFSAGTVPASEVHPLAVQVMREKGIDLSA
CCCCEEEEECCCHHHHHHHHHHHHHHCCCCCHHCCCCCCCHHHHHHHHHHHHHCCCCCCC
NRPKKVDEFLTKPFDYVVTVCDSAKESCPLFTGQVKHRQHIGFDDPAAATGSSEEVLAEF
CCCHHHHHHHHCCHHHHHHHHHHHHHCCCCCCCCHHHHHCCCCCCCCCCCCCHHHHHHHH
RRVRDEIEQEFGKFYRETIRGEKP
HHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11058132 [H]