Click here to switch to the map view.

The map label for this gene is pab [H]

Identifier: 21674529

GI number: 21674529

Start: 1622923

End: 1624809

Strand: Reverse

Name: pab [H]

Synonym: CT1712

Alternate gene names: 21674529

Gene position: 1624809-1622923 (Counterclockwise)

Preceding gene: 21674530

Following gene: 21674528

Centisome position: 75.4

GC content: 63.49

Gene sequence:

>1887_bases
GTGGCTCGAAGAGGTGCTCGGGAAACCCATTCTGATCGAAGCCCGCGTCCGGTAATGGCTTTGTACGAAAAGCTTGCTAG
TCCGGGATCGCTCTGGTTTGAATCGACCTTGCCCGGCGCGCTCTACGGCGATTCCCTCTTTTTCTCCGATCCGCTCGAAA
CGCTGACGCTCCATGCGGGCGACAGCGTCGCGCCGTGGTTCGCCACGCTGGAGTCGCGGCTCGACGCAGGCCTCTGCCTC
GCTGGATGGCTCAGCTATGAGGCGGGTTACCTGCTCGATCCGGCACTCGCGGCTCTCGCATCTGCCGGGGCTGATCGCGA
GCTTCTTGGCTGGTTCGGCGTCTATGGTCGCCCGGAGCGCGTCCGCCGCGAAACGGTTGAGGCCGAGGACGCGGCGGCAG
CGGCGCGGAGCTGCGCAGTCAGCGGATTCGGTTTCGAGTTCAGCGAGGCGGAGTATTGCGAGCGCATCGACAGACTTCGG
ACTGAGATCGCGGCGGGCAACGTCTATCAGGCAAACTTCACCGGGCGCTGCCGCTTCAGCTTCGACGGTGCTGTCGAAGC
GCTTTACGTCAAGATGAAGCGTCGCCAACCCTCGCCGTGGTCGGCCTTCCTCAACACCGGCGACCGTCAGATTCTTTCCT
TTTCCCCTGAACTCTTTTTCGCCAGCGATGGCCGCTTGATCGAAACCATGCCGATGAAGGGCACCGCGCCGCGCCGCGAG
CGGCCCGAAGAAGACCTCGCCGAAAAGGCGGGGCTGGCAAAGTGTGAGAAGAACCGCGCGGAGAACCTGATGATCGTCGA
TCTGTTGCGCAACGACCTGGGGCGCATCTGCGCGACCGGCTCGGTGCAGGCCTCCGGGCTGTTCGAGACGCAGACCTATC
CGACGCTGCACCAGATGGTTTCGACCGTGCGTGGCGAGCTGCGTCCGGCGACCCGGCTGCACGATCTTTTCCGGGCGCTG
TTTCCCTCCGGCTCCGTGACCGGTGCGCCGAAGGTGCGGGCGATGCAGCTCATCTGCGAGTTGGAAAAAAGCCTGCGAGG
GGTTTACACCGGCGCGGTCGGTTTCATGCTGCCCGAAGGGCGTATGGCCTTCAACGTGGCGATCCGTACCATCGAACTGC
GAGGGCAGAGCGGTGTTTACGGTACGGGGAGCGGCATCGTCTGGGACTCCGACCCGCACGCGGAGTTTCGCGAATGTATG
CTCAAGACGCGGATTCTCGCCGACCTCGTGCCGCCCTCCGATCCATCGGTTCCGGGCATTTTCGAGACGATGCAATGGAA
CGGCGGGGAGTTCCTGCTGGCTGGCGACCATCTCGACCGGCTCGTTTCGTCCGCCATGGCGCTCGGATTTACGTTCGACC
GCGCCGCTATCGCCGAGGCGCTGTCTGCCAAGGAACGCGAGTTGAGGAAAAACGGTGGCAGGCATCGCGTGCGGCTTACA
CTTTCTCACGACGGTGGGATTTTGATAACTTCGGAGCCGTTCGATTTCGATGCATCCGGCAAGTCCGTCCGGGTCTGCAT
TGCCGCCGAGCGGGTCGATTCGCGCGATCCGCTGCTTCGGCACAAGAGCGTCGCTCGCGAGCGGTACGATCGCGCCTTGC
GCGAGGCGCGGGAGCGTGGATTCGGCGAAGTACTGTTTCTGAACGAGCGCAACGAAGTCACCGAAGGGGCGATCAGCAAT
GTGCTCGCCCGCATCGACGGGCGCTGGCTGACGCCGCCGGAGTCGTGCGGACTGCTCAATGGTGTTTTCCGCCGCTACCT
CCTGCGCTCGCGCCCGTGGATCGTCGAAAAAGCGTTTACCCTTGACGATCTGCACCGGGCCGATATGGTGTTCGTTTGCA
ACTCACTGCGCGGCGTGCGCCCGGTGGCGATCGTCTTTCCGGAATAA

Upstream 100 bases:

>100_bases
AGTCGATCACGGCCCGCATCGACCAGGAGCGCATCGTGCTCGAAGCGCTCACGCAGTTCGAGCCTGACATCGAACTCTGG
GCGGCTTGCGGGCTAAAGGA

Downstream 100 bases:

>100_bases
GCGCACCGGAGGTTGAAGCGCAACGGCTTGAGCTGTATATTGATGCTAGGACTCATCTTAAGCAACCGCTAACAGCTTTC
CACCATGAGAGACCACACGC

Product: para-aminobenzoate synthetase, putative

Products: NA

Alternate protein names: P-aminobenzoic acid synthase; PABA synthase [H]

Number of amino acids: Translated: 628; Mature: 627

Protein sequence:

>628_residues
MARRGARETHSDRSPRPVMALYEKLASPGSLWFESTLPGALYGDSLFFSDPLETLTLHAGDSVAPWFATLESRLDAGLCL
AGWLSYEAGYLLDPALAALASAGADRELLGWFGVYGRPERVRRETVEAEDAAAAARSCAVSGFGFEFSEAEYCERIDRLR
TEIAAGNVYQANFTGRCRFSFDGAVEALYVKMKRRQPSPWSAFLNTGDRQILSFSPELFFASDGRLIETMPMKGTAPRRE
RPEEDLAEKAGLAKCEKNRAENLMIVDLLRNDLGRICATGSVQASGLFETQTYPTLHQMVSTVRGELRPATRLHDLFRAL
FPSGSVTGAPKVRAMQLICELEKSLRGVYTGAVGFMLPEGRMAFNVAIRTIELRGQSGVYGTGSGIVWDSDPHAEFRECM
LKTRILADLVPPSDPSVPGIFETMQWNGGEFLLAGDHLDRLVSSAMALGFTFDRAAIAEALSAKERELRKNGGRHRVRLT
LSHDGGILITSEPFDFDASGKSVRVCIAAERVDSRDPLLRHKSVARERYDRALREARERGFGEVLFLNERNEVTEGAISN
VLARIDGRWLTPPESCGLLNGVFRRYLLRSRPWIVEKAFTLDDLHRADMVFVCNSLRGVRPVAIVFPE

Sequences:

>Translated_628_residues
MARRGARETHSDRSPRPVMALYEKLASPGSLWFESTLPGALYGDSLFFSDPLETLTLHAGDSVAPWFATLESRLDAGLCL
AGWLSYEAGYLLDPALAALASAGADRELLGWFGVYGRPERVRRETVEAEDAAAAARSCAVSGFGFEFSEAEYCERIDRLR
TEIAAGNVYQANFTGRCRFSFDGAVEALYVKMKRRQPSPWSAFLNTGDRQILSFSPELFFASDGRLIETMPMKGTAPRRE
RPEEDLAEKAGLAKCEKNRAENLMIVDLLRNDLGRICATGSVQASGLFETQTYPTLHQMVSTVRGELRPATRLHDLFRAL
FPSGSVTGAPKVRAMQLICELEKSLRGVYTGAVGFMLPEGRMAFNVAIRTIELRGQSGVYGTGSGIVWDSDPHAEFRECM
LKTRILADLVPPSDPSVPGIFETMQWNGGEFLLAGDHLDRLVSSAMALGFTFDRAAIAEALSAKERELRKNGGRHRVRLT
LSHDGGILITSEPFDFDASGKSVRVCIAAERVDSRDPLLRHKSVARERYDRALREARERGFGEVLFLNERNEVTEGAISN
VLARIDGRWLTPPESCGLLNGVFRRYLLRSRPWIVEKAFTLDDLHRADMVFVCNSLRGVRPVAIVFPE
>Mature_627_residues
ARRGARETHSDRSPRPVMALYEKLASPGSLWFESTLPGALYGDSLFFSDPLETLTLHAGDSVAPWFATLESRLDAGLCLA
GWLSYEAGYLLDPALAALASAGADRELLGWFGVYGRPERVRRETVEAEDAAAAARSCAVSGFGFEFSEAEYCERIDRLRT
EIAAGNVYQANFTGRCRFSFDGAVEALYVKMKRRQPSPWSAFLNTGDRQILSFSPELFFASDGRLIETMPMKGTAPRRER
PEEDLAEKAGLAKCEKNRAENLMIVDLLRNDLGRICATGSVQASGLFETQTYPTLHQMVSTVRGELRPATRLHDLFRALF
PSGSVTGAPKVRAMQLICELEKSLRGVYTGAVGFMLPEGRMAFNVAIRTIELRGQSGVYGTGSGIVWDSDPHAEFRECML
KTRILADLVPPSDPSVPGIFETMQWNGGEFLLAGDHLDRLVSSAMALGFTFDRAAIAEALSAKERELRKNGGRHRVRLTL
SHDGGILITSEPFDFDASGKSVRVCIAAERVDSRDPLLRHKSVARERYDRALREARERGFGEVLFLNERNEVTEGAISNV
LARIDGRWLTPPESCGLLNGVFRRYLLRSRPWIVEKAFTLDDLHRADMVFVCNSLRGVRPVAIVFPE

Specific function: Catalyzes the biosynthesis of 4-amino-4-deoxychorismate (ADC) from chorismate and glutamine [H]

COG id: COG0147

COG function: function code EH; Anthranilate/para-aminobenzoate synthases component I

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 glutamine amidotransferase type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1788114, Length=289, Percent_Identity=37.3702422145329, Blast_Score=199, Evalue=6e-52,
Organism=Escherichia coli, GI1787518, Length=270, Percent_Identity=35.9259259259259, Blast_Score=138, Evalue=1e-33,
Organism=Escherichia coli, GI1786809, Length=201, Percent_Identity=30.3482587064677, Blast_Score=77, Evalue=3e-15,
Organism=Saccharomyces cerevisiae, GI6320935, Length=253, Percent_Identity=37.9446640316205, Blast_Score=162, Evalue=1e-40,
Organism=Saccharomyces cerevisiae, GI6324361, Length=278, Percent_Identity=29.136690647482, Blast_Score=97, Evalue=1e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005801
- InterPro:   IPR006805
- InterPro:   IPR006220
- InterPro:   IPR001317
- InterPro:   IPR015890
- InterPro:   IPR011702
- InterPro:   IPR017926
- InterPro:   IPR000991
- InterPro:   IPR005802
- InterPro:   IPR006221 [H]

Pfam domain/function: PF04715 Anth_synt_I_N; PF00425 Chorismate_bind; PF00117 GATase [H]

EC number: =2.6.1.85 [H]

Molecular weight: Translated: 69606; Mature: 69475

Theoretical pI: Translated: 6.84; Mature: 6.84

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MARRGARETHSDRSPRPVMALYEKLASPGSLWFESTLPGALYGDSLFFSDPLETLTLHAG
CCCCCCCCCCCCCCCCHHHHHHHHHCCCCCEEECCCCCCCCCCCCCEECCCHHHEEEECC
DSVAPWFATLESRLDAGLCLAGWLSYEAGYLLDPALAALASAGADRELLGWFGVYGRPER
CCCHHHHHHHHHHCCCCHHHHHHHHCCCCCEECHHHHHHHHCCCCHHHHHHHCCCCCHHH
VRRETVEAEDAAAAARSCAVSGFGFEFSEAEYCERIDRLRTEIAAGNVYQANFTGRCRFS
HHHHHHHHHHHHHHHHHHEEECCCCCCCHHHHHHHHHHHHHHHHCCCEEEECCCEEEEEE
FDGAVEALYVKMKRRQPSPWSAFLNTGDRQILSFSPELFFASDGRLIETMPMKGTAPRRE
CCCHHHHHHHHHHHCCCCCHHHHHCCCCCEEEEECCCEEEECCCCEEEECCCCCCCCCCC
RPEEDLAEKAGLAKCEKNRAENLMIVDLLRNDLGRICATGSVQASGLFETQTYPTLHQMV
CCHHHHHHHHCHHHHHHHCCCCEEEHHHHHHHHHHHCCCCCCEECCCCCCCCCHHHHHHH
STVRGELRPATRLHDLFRALFPSGSVTGAPKVRAMQLICELEKSLRGVYTGAVGFMLPEG
HHHHHCCCHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHEEECCC
RMAFNVAIRTIELRGQSGVYGTGSGIVWDSDPHAEFRECMLKTRILADLVPPSDPSVPGI
CEEEEEEEEEEEECCCCCCEECCCCEEECCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCH
FETMQWNGGEFLLAGDHLDRLVSSAMALGFTFDRAAIAEALSAKERELRKNGGRHRVRLT
HHHHCCCCCEEEEECHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEEE
LSHDGGILITSEPFDFDASGKSVRVCIAAERVDSRDPLLRHKSVARERYDRALREARERG
EECCCCEEEECCCCCCCCCCCEEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHCC
FGEVLFLNERNEVTEGAISNVLARIDGRWLTPPESCGLLNGVFRRYLLRSRPWIVEKAFT
CCEEEEEECCCCHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHCCCCEEEECCC
LDDLHRADMVFVCNSLRGVRPVAIVFPE
HHHHHHHHHHHHHHHCCCCCEEEEEECC
>Mature Secondary Structure 
ARRGARETHSDRSPRPVMALYEKLASPGSLWFESTLPGALYGDSLFFSDPLETLTLHAG
CCCCCCCCCCCCCCCHHHHHHHHHCCCCCEEECCCCCCCCCCCCCEECCCHHHEEEECC
DSVAPWFATLESRLDAGLCLAGWLSYEAGYLLDPALAALASAGADRELLGWFGVYGRPER
CCCHHHHHHHHHHCCCCHHHHHHHHCCCCCEECHHHHHHHHCCCCHHHHHHHCCCCCHHH
VRRETVEAEDAAAAARSCAVSGFGFEFSEAEYCERIDRLRTEIAAGNVYQANFTGRCRFS
HHHHHHHHHHHHHHHHHHEEECCCCCCCHHHHHHHHHHHHHHHHCCCEEEECCCEEEEEE
FDGAVEALYVKMKRRQPSPWSAFLNTGDRQILSFSPELFFASDGRLIETMPMKGTAPRRE
CCCHHHHHHHHHHHCCCCCHHHHHCCCCCEEEEECCCEEEECCCCEEEECCCCCCCCCCC
RPEEDLAEKAGLAKCEKNRAENLMIVDLLRNDLGRICATGSVQASGLFETQTYPTLHQMV
CCHHHHHHHHCHHHHHHHCCCCEEEHHHHHHHHHHHCCCCCCEECCCCCCCCCHHHHHHH
STVRGELRPATRLHDLFRALFPSGSVTGAPKVRAMQLICELEKSLRGVYTGAVGFMLPEG
HHHHHCCCHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHEEECCC
RMAFNVAIRTIELRGQSGVYGTGSGIVWDSDPHAEFRECMLKTRILADLVPPSDPSVPGI
CEEEEEEEEEEEECCCCCCEECCCCEEECCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCH
FETMQWNGGEFLLAGDHLDRLVSSAMALGFTFDRAAIAEALSAKERELRKNGGRHRVRLT
HHHHCCCCCEEEEECHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEEE
LSHDGGILITSEPFDFDASGKSVRVCIAAERVDSRDPLLRHKSVARERYDRALREARERG
EECCCCEEEECCCCCCCCCCCEEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHCC
FGEVLFLNERNEVTEGAISNVLARIDGRWLTPPESCGLLNGVFRRYLLRSRPWIVEKAFT
CCEEEEEECCCCHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHCCCCEEEECCC
LDDLHRADMVFVCNSLRGVRPVAIVFPE
HHHHHHHHHHHHHHHCCCCCEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8472954 [H]