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The map label for this gene is rpe [H]

Identifier: 21674488

GI number: 21674488

Start: 1581093

End: 1581755

Strand: Direct

Name: rpe [H]

Synonym: CT1670

Alternate gene names: 21674488

Gene position: 1581093-1581755 (Clockwise)

Preceding gene: 21674487

Following gene: 21674493

Centisome position: 73.37

GC content: 56.41

Gene sequence:

>663_bases
ATGCCCGGAAAAACCACACTGCTTGCCCCGTCGATCCTCTCCGCAGACTTCACGAACCTGAAAGCCTCGGTCGAGCTTGC
TGAAAAGGCCGGTGCCGACTGGATGCACTGCGATGTGATGGATGGCATTTTCGTGCCCAACATCACCTTCGGCTCTTTCA
TCGTGCAGGCGATTAAACAGTGCACCAGCATAGTGATTGATACTCACCTGATGATCGTCGACCCCGACAAGTATATCGAA
GATTTCGCCAAGGCCGGTTCCGACCAGATTACCGTGCACCTCGAAGCCTGCCCGCACCTGCACCGCACGATCCAGCTCAT
CAAAAGCCTTGGGGTGAAGGCTGGCGTCTCAATCAACCCCGCAACTCCGGTGTCGCTGCTTGAACCGGTACTCGCCGATC
TCGATCTCGTGCTCCTGATGTCGGTCAACCCCGGCTTCGGCGGGCAGAAATTCATACCCGGCGCGATCAAAAAAATCATG
CAACTCGACGCCATGCGCATGGAGATGAATCCGGAGATGGTGATTGCCGTCGATGGAGGCGTCACCGAAGAGAATGCTGC
GATGATAGTCGATGCCGGAGCAGATGCACTCATCGCAGGCACCGCCTTCTTCCGCGCTCCCGATCCGGTAGCCGCAGCGA
AAAAATTAAAAGGGCTGGAGTAA

Upstream 100 bases:

>100_bases
CGTGGCGCTTCTCACAGACGAAACTGACCGATTTCACCTTTAACTTTGGAATCGGAGAAACGTTTTAACCGAATTCATTC
ACGCTTAACATTTTGAATCT

Downstream 100 bases:

>100_bases
GAAAAGAAAAAGACTTATAGGTCTCACAGGGCCTATAAGTCTTCTATGAAAAGAGAAGATTTCCGGAAGTTATCTGTCCA
CCACTCCCCCTAACCCCACG

Product: ribulose-phosphate 3-epimerase

Products: NA

Alternate protein names: Pentose-5-phosphate 3-epimerase; PPE; R5P3E [H]

Number of amino acids: Translated: 220; Mature: 219

Protein sequence:

>220_residues
MPGKTTLLAPSILSADFTNLKASVELAEKAGADWMHCDVMDGIFVPNITFGSFIVQAIKQCTSIVIDTHLMIVDPDKYIE
DFAKAGSDQITVHLEACPHLHRTIQLIKSLGVKAGVSINPATPVSLLEPVLADLDLVLLMSVNPGFGGQKFIPGAIKKIM
QLDAMRMEMNPEMVIAVDGGVTEENAAMIVDAGADALIAGTAFFRAPDPVAAAKKLKGLE

Sequences:

>Translated_220_residues
MPGKTTLLAPSILSADFTNLKASVELAEKAGADWMHCDVMDGIFVPNITFGSFIVQAIKQCTSIVIDTHLMIVDPDKYIE
DFAKAGSDQITVHLEACPHLHRTIQLIKSLGVKAGVSINPATPVSLLEPVLADLDLVLLMSVNPGFGGQKFIPGAIKKIM
QLDAMRMEMNPEMVIAVDGGVTEENAAMIVDAGADALIAGTAFFRAPDPVAAAKKLKGLE
>Mature_219_residues
PGKTTLLAPSILSADFTNLKASVELAEKAGADWMHCDVMDGIFVPNITFGSFIVQAIKQCTSIVIDTHLMIVDPDKYIED
FAKAGSDQITVHLEACPHLHRTIQLIKSLGVKAGVSINPATPVSLLEPVLADLDLVLLMSVNPGFGGQKFIPGAIKKIMQ
LDAMRMEMNPEMVIAVDGGVTEENAAMIVDAGADALIAGTAFFRAPDPVAAAKKLKGLE

Specific function: Unknown

COG id: COG0036

COG function: function code G; Pentose-5-phosphate-3-epimerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ribulose-phosphate 3-epimerase family [H]

Homologues:

Organism=Homo sapiens, GI40385883, Length=214, Percent_Identity=37.8504672897196, Blast_Score=152, Evalue=2e-37,
Organism=Homo sapiens, GI219879828, Length=214, Percent_Identity=36.4485981308411, Blast_Score=143, Evalue=1e-34,
Organism=Homo sapiens, GI24307923, Length=169, Percent_Identity=31.9526627218935, Blast_Score=94, Evalue=1e-19,
Organism=Escherichia coli, GI1789788, Length=206, Percent_Identity=47.5728155339806, Blast_Score=183, Evalue=8e-48,
Organism=Escherichia coli, GI1790523, Length=196, Percent_Identity=36.734693877551, Blast_Score=139, Evalue=1e-34,
Organism=Escherichia coli, GI1790754, Length=215, Percent_Identity=31.1627906976744, Blast_Score=97, Evalue=6e-22,
Organism=Caenorhabditis elegans, GI17552948, Length=216, Percent_Identity=38.4259259259259, Blast_Score=156, Evalue=6e-39,
Organism=Saccharomyces cerevisiae, GI6322341, Length=216, Percent_Identity=41.6666666666667, Blast_Score=169, Evalue=5e-43,
Organism=Drosophila melanogaster, GI24586301, Length=211, Percent_Identity=38.3886255924171, Blast_Score=150, Evalue=7e-37,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR000056
- InterPro:   IPR011060 [H]

Pfam domain/function: PF00834 Ribul_P_3_epim [H]

EC number: =5.1.3.1 [H]

Molecular weight: Translated: 23368; Mature: 23236

Theoretical pI: Translated: 4.72; Mature: 4.72

Prosite motif: PS01086 RIBUL_P_3_EPIMER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
5.0 %Met     (Translated Protein)
6.4 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
4.6 %Met     (Mature Protein)
5.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPGKTTLLAPSILSADFTNLKASVELAEKAGADWMHCDVMDGIFVPNITFGSFIVQAIKQ
CCCCCCEECCHHHHCCHHHHHHHHHHHHHCCCCEEEEEHHCCEECCCCCHHHHHHHHHHH
CTSIVIDTHLMIVDPDKYIEDFAKAGSDQITVHLEACPHLHRTIQLIKSLGVKAGVSINP
HHHHHHHCEEEEECCHHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHHHCCCCCCCEECC
ATPVSLLEPVLADLDLVLLMSVNPGFGGQKFIPGAIKKIMQLDAMRMEMNPEMVIAVDGG
CCCHHHHHHHHHCCCEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCEEEEECCC
VTEENAAMIVDAGADALIAGTAFFRAPDPVAAAKKLKGLE
CCCCCCEEEEECCCCEEEECHHHCCCCCHHHHHHHHCCCC
>Mature Secondary Structure 
PGKTTLLAPSILSADFTNLKASVELAEKAGADWMHCDVMDGIFVPNITFGSFIVQAIKQ
CCCCCEECCHHHHCCHHHHHHHHHHHHHCCCCEEEEEHHCCEECCCCCHHHHHHHHHHH
CTSIVIDTHLMIVDPDKYIEDFAKAGSDQITVHLEACPHLHRTIQLIKSLGVKAGVSINP
HHHHHHHCEEEEECCHHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHHHCCCCCCCEECC
ATPVSLLEPVLADLDLVLLMSVNPGFGGQKFIPGAIKKIMQLDAMRMEMNPEMVIAVDGG
CCCHHHHHHHHHCCCEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCEEEEECCC
VTEENAAMIVDAGADALIAGTAFFRAPDPVAAAKKLKGLE
CCCCCCEEEEECCCCEEEECHHHCCCCCHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9534248; 9384377 [H]