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The map label for this gene is ruvC

Identifier: 21674482

GI number: 21674482

Start: 1573044

End: 1573604

Strand: Reverse

Name: ruvC

Synonym: CT1664

Alternate gene names: 21674482

Gene position: 1573604-1573044 (Counterclockwise)

Preceding gene: 21674483

Following gene: 21674481

Centisome position: 73.02

GC content: 64.35

Gene sequence:

>561_bases
ATGATTGTACTGGGCATCGATCCGGGCAGCCGCAAAACCGGCTATGGCGTCATCGCCGAAACGGCGGCGGGCTATCGCGT
GCTTGGATGCGGCCTTGTTCGCCCTCGCGCAGCGGATACGCTGCATGAGCGGATCAGCCAGCTCTGCGCGGGCCTCGACG
AGGTGATCGAGCAGCTGAAGCCCGAGGCGGTGGCGCTTGAGACGGCCTTCGTGGGGCGCAATGTCAGAAGCGCGCTGATT
CTCGGCCAGGTCAGGGGGGCGGTGCTTGCCACGGTGATGAGGCATAGCTTGCCGGTGCGTGAATACGCGCCGCGCGAAAT
CAAGCTCTCGGTTACCGGCACCGGTTCGGCGTGCAAGGAGCAGGTGGCGGCAATGCTGTCGCGGATGCTCGAGCTTGGCG
GTGAGCTGAAGCCTCTCGATGTTACCGATGCGCTTGGCATCGCCTACTGCGATCTCGCTCGGGGTGCATCTTCGCTCGGC
GGCCAGTTGCGCAAGAACGGAAAAGGGCGGAGCAAGGGATGGGCGGCGTTCGTAAACGAGCATCCCGAGCTGATGGCCTG
A

Upstream 100 bases:

>100_bases
GCTGATCGACGCGCTCGAAAACAGCGATGACGTCCAGGCGGTCTACAGCAACATGGACATGAGTGAAAGCGTCATGAGCG
TGCTTGAAGAAGAGTAACCC

Downstream 100 bases:

>100_bases
TTTTTTATCAACGAGTGGTGCCGGAGTTTGGATTTCGGCATCTGTTTTGTCAAACGATCCTCAGGATGACCTTCGGGTCT
CTTTTCCGGAACCAAACAAG

Product: Holliday junction resolvase

Products: NA

Alternate protein names: Holliday junction nuclease ruvC; Holliday junction resolvase ruvC

Number of amino acids: Translated: 186; Mature: 186

Protein sequence:

>186_residues
MIVLGIDPGSRKTGYGVIAETAAGYRVLGCGLVRPRAADTLHERISQLCAGLDEVIEQLKPEAVALETAFVGRNVRSALI
LGQVRGAVLATVMRHSLPVREYAPREIKLSVTGTGSACKEQVAAMLSRMLELGGELKPLDVTDALGIAYCDLARGASSLG
GQLRKNGKGRSKGWAAFVNEHPELMA

Sequences:

>Translated_186_residues
MIVLGIDPGSRKTGYGVIAETAAGYRVLGCGLVRPRAADTLHERISQLCAGLDEVIEQLKPEAVALETAFVGRNVRSALI
LGQVRGAVLATVMRHSLPVREYAPREIKLSVTGTGSACKEQVAAMLSRMLELGGELKPLDVTDALGIAYCDLARGASSLG
GQLRKNGKGRSKGWAAFVNEHPELMA
>Mature_186_residues
MIVLGIDPGSRKTGYGVIAETAAGYRVLGCGLVRPRAADTLHERISQLCAGLDEVIEQLKPEAVALETAFVGRNVRSALI
LGQVRGAVLATVMRHSLPVREYAPREIKLSVTGTGSACKEQVAAMLSRMLELGGELKPLDVTDALGIAYCDLARGASSLG
GQLRKNGKGRSKGWAAFVNEHPELMA

Specific function: Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leav

COG id: COG0817

COG function: function code L; Holliday junction resolvasome, endonuclease subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ruvC family

Homologues:

Organism=Escherichia coli, GI1788170, Length=131, Percent_Identity=45.0381679389313, Blast_Score=113, Evalue=8e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RUVC_CHLTE (Q8KBW8)

Other databases:

- EMBL:   AE006470
- RefSeq:   NP_662547.1
- ProteinModelPortal:   Q8KBW8
- SMR:   Q8KBW8
- GeneID:   1007091
- GenomeReviews:   AE006470_GR
- KEGG:   cte:CT1664
- NMPDR:   fig|194439.1.peg.1641
- TIGR:   CT1664
- HOGENOM:   HBG437552
- OMA:   RTGWGVI
- ProtClustDB:   CLSK2303952
- BioCyc:   CTEP194439:CT_1664-MONOMER
- BRENDA:   3.1.22.4
- HAMAP:   MF_00034
- InterPro:   IPR012337
- InterPro:   IPR020563
- InterPro:   IPR002176
- PRINTS:   PR00696
- TIGRFAMs:   TIGR00228

Pfam domain/function: PF02075 RuvC; SSF53098 RNaseH_fold

EC number: =3.1.22.4

Molecular weight: Translated: 19695; Mature: 19695

Theoretical pI: Translated: 8.95; Mature: 8.95

Prosite motif: PS01321 RUVC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIVLGIDPGSRKTGYGVIAETAAGYRVLGCGLVRPRAADTLHERISQLCAGLDEVIEQLK
CEEEECCCCCCCCCCCEEECCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHC
PEAVALETAFVGRNVRSALILGQVRGAVLATVMRHSLPVREYAPREIKLSVTGTGSACKE
CHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCCEEEEEEECCCHHHHH
QVAAMLSRMLELGGELKPLDVTDALGIAYCDLARGASSLGGQLRKNGKGRSKGWAAFVNE
HHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCHHHHHHHHHHCCCCCCCCHHHHHCC
HPELMA
CCCCCC
>Mature Secondary Structure
MIVLGIDPGSRKTGYGVIAETAAGYRVLGCGLVRPRAADTLHERISQLCAGLDEVIEQLK
CEEEECCCCCCCCCCCEEECCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHC
PEAVALETAFVGRNVRSALILGQVRGAVLATVMRHSLPVREYAPREIKLSVTGTGSACKE
CHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCCEEEEEEECCCHHHHH
QVAAMLSRMLELGGELKPLDVTDALGIAYCDLARGASSLGGQLRKNGKGRSKGWAAFVNE
HHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCHHHHHHHHHHCCCCCCCCHHHHHCC
HPELMA
CCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12093901