Click here to switch to the map view.

The map label for this gene is pgsA1 [H]

Identifier: 21674481

GI number: 21674481

Start: 1572382

End: 1572978

Strand: Reverse

Name: pgsA1 [H]

Synonym: CT1663

Alternate gene names: 21674481

Gene position: 1572978-1572382 (Counterclockwise)

Preceding gene: 21674482

Following gene: 21674478

Centisome position: 72.99

GC content: 54.61

Gene sequence:

>597_bases
ATGACCTTCGGGTCTCTTTTCCGGAACCAAACAAGAACCGTTGTGAAGGGACATATTTTCAATCTCCCCAATTCGCTGAG
CATCCTGAGGATTCTGCTGATTCCCTGGTTCATCTACTACCTCGACGCGGGTCAGACGCACATCGCCCTCATCATCATGG
TGGTGGCGCTGCTTTCCGACTGGTTCGACGGCCAGATGGCCCGGTGGACCAACGAGGTCTCCGACATGGGCAAGATTCTC
GACCCCCTGGCCGACAAACTCTGCCTGGCCAGCGTCGCTCTCTACTACCTCTGGAAAGGGGAGTTGCCGGTATGGTTCGT
GGTGTTCGTTGTGTTTCGTGACCTGGTGATTTTCCTCGGCGCGGCCTGGATTCGTCACCGGCACAACGTGCTCACCACTT
CGCTCTGGCCCGGCAAGTGGGCGGTGGGATTCGTCTCAATGATGTTCATCTCGATGGTCTGGCCGCTTCCTGTTTTTCGG
CAGTGGCCGGTCAAAGAGTTCTTTATGTATCTTTCTGCTGCCACCCTTTTCTACTCGTTTGTAGAATACTGCATCAGGTT
CTACAAAATCCAGAAAGGGGCGGAATTCAAGGCCTGA

Upstream 100 bases:

>100_bases
CGTTCGTAAACGAGCATCCCGAGCTGATGGCCTGATTTTTTATCAACGAGTGGTGCCGGAGTTTGGATTTCGGCATCTGT
TTTGTCAAACGATCCTCAGG

Downstream 100 bases:

>100_bases
TTTTCCTCTTTTTTTCATAATCTCTTTGAATGCAGGAGGTTATCCACAGATTAACGCCTGCAATATGGATAAGTGTACAT
AAGTAACGGCCAGTGTTATA

Product: CDP-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase, putative

Products: NA

Alternate protein names: Phosphatidylglycerophosphate synthase; PGP synthase [H]

Number of amino acids: Translated: 198; Mature: 197

Protein sequence:

>198_residues
MTFGSLFRNQTRTVVKGHIFNLPNSLSILRILLIPWFIYYLDAGQTHIALIIMVVALLSDWFDGQMARWTNEVSDMGKIL
DPLADKLCLASVALYYLWKGELPVWFVVFVVFRDLVIFLGAAWIRHRHNVLTTSLWPGKWAVGFVSMMFISMVWPLPVFR
QWPVKEFFMYLSAATLFYSFVEYCIRFYKIQKGAEFKA

Sequences:

>Translated_198_residues
MTFGSLFRNQTRTVVKGHIFNLPNSLSILRILLIPWFIYYLDAGQTHIALIIMVVALLSDWFDGQMARWTNEVSDMGKIL
DPLADKLCLASVALYYLWKGELPVWFVVFVVFRDLVIFLGAAWIRHRHNVLTTSLWPGKWAVGFVSMMFISMVWPLPVFR
QWPVKEFFMYLSAATLFYSFVEYCIRFYKIQKGAEFKA
>Mature_197_residues
TFGSLFRNQTRTVVKGHIFNLPNSLSILRILLIPWFIYYLDAGQTHIALIIMVVALLSDWFDGQMARWTNEVSDMGKILD
PLADKLCLASVALYYLWKGELPVWFVVFVVFRDLVIFLGAAWIRHRHNVLTTSLWPGKWAVGFVSMMFISMVWPLPVFRQ
WPVKEFFMYLSAATLFYSFVEYCIRFYKIQKGAEFKA

Specific function: This protein catalyzes the committed step to the synthesis of the acidic phospholipids [H]

COG id: COG0558

COG function: function code I; Phosphatidylglycerophosphate synthase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CDP-alcohol phosphatidyltransferase class-I family [H]

Homologues:

Organism=Homo sapiens, GI188536108, Length=108, Percent_Identity=33.3333333333333, Blast_Score=65, Evalue=5e-11,
Organism=Drosophila melanogaster, GI24650130, Length=110, Percent_Identity=36.3636363636364, Blast_Score=77, Evalue=7e-15,
Organism=Drosophila melanogaster, GI24650126, Length=110, Percent_Identity=36.3636363636364, Blast_Score=77, Evalue=7e-15,
Organism=Drosophila melanogaster, GI24650128, Length=110, Percent_Identity=36.3636363636364, Blast_Score=77, Evalue=7e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000462
- InterPro:   IPR004570 [H]

Pfam domain/function: PF01066 CDP-OH_P_transf [H]

EC number: =2.7.8.5 [H]

Molecular weight: Translated: 23154; Mature: 23023

Theoretical pI: Translated: 9.74; Mature: 9.74

Prosite motif: PS00379 CDP_ALCOHOL_P_TRANSF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTFGSLFRNQTRTVVKGHIFNLPNSLSILRILLIPWFIYYLDAGQTHIALIIMVVALLSD
CCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHH
WFDGQMARWTNEVSDMGKILDPLADKLCLASVALYYLWKGELPVWFVVFVVFRDLVIFLG
HCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHH
AAWIRHRHNVLTTSLWPGKWAVGFVSMMFISMVWPLPVFRQWPVKEFFMYLSAATLFYSF
HHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCHHHHCCCHHHHHHHHHHHHHHHHH
VEYCIRFYKIQKGAEFKA
HHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
TFGSLFRNQTRTVVKGHIFNLPNSLSILRILLIPWFIYYLDAGQTHIALIIMVVALLSD
CHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHH
WFDGQMARWTNEVSDMGKILDPLADKLCLASVALYYLWKGELPVWFVVFVVFRDLVIFLG
HCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHH
AAWIRHRHNVLTTSLWPGKWAVGFVSMMFISMVWPLPVFRQWPVKEFFMYLSAATLFYSF
HHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCHHHHCCCHHHHHHHHHHHHHHHHH
VEYCIRFYKIQKGAEFKA
HHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]