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The map label for this gene is suhB [H]

Identifier: 21674479

GI number: 21674479

Start: 1569817

End: 1570611

Strand: Direct

Name: suhB [H]

Synonym: CT1661

Alternate gene names: 21674479

Gene position: 1569817-1570611 (Clockwise)

Preceding gene: 21674476

Following gene: 21674480

Centisome position: 72.85

GC content: 61.51

Gene sequence:

>795_bases
ATGAACCTCGAACTCCAGACGGCCGTGAAGGCAGCCAAAGCCGCAGGCGCGATTACGCTTTCGAGATTCGGCGAACTTTC
TCATCGCGAGATCGTCGCCAAAGAGTACAAGGATTTCGTCACCGAAGTTGACAAGCAGTGTGAAGCAACCATCACGGCCA
CCATCACCGAATCGTTCCCTGATGACGGTTTGCTCTGCGAGGAGGGCACCAGCGGCAGTGGCGCTTCCGGGCGCACCTGG
ATCGTCGATCCGCTCGATGGCACGCTGAACTTTATCCACTCGTTTCCGGTGTTCGGCATCAGCATCGCCATGCGCGACGC
ATCCGGCGAACTCGCGGTGGGCGTGGTTTATCAGCCGGTGCTCGACGAGCTGTTCACTGCCGTCAAGGGACGGGGCGCGT
TCCTGAACGGTAAGCGCATCAGTGTCTCGACGCGCGAAGAGATGCAGAGCTATCTCTTCGCCACCGGCCTGCCCTTCAGG
GATTACGATCACTACATGGACGGCTACATCGGCCTCTTGCGGGATGTCATCAAGGACTCGGCAGGCATCCGTCGCGCCGG
ATCGGCCTCCATCGACCTGGCCTACACCGCCGCCGGACGCTTCGACGGCTTCTTCGAGTACCGACTCTTTCCGTGGGACT
TCGCGGCGGGCGTGCTGCTGGTGCGCGAAGCGGGTGGCATCGTAACCGGCATTGCCGGCTCGGATGATGTGTTCGCCCAT
ACGAGCATCCTTGCTGGAAGCCCGCTCACCCATCCGCTGCTGCTGGAAAAAGCCCGGCGGCATTTCGGGGCCTGA

Upstream 100 bases:

>100_bases
ATTTAATTCCCGCGTGCCGTTATCTTGCTGCGCCTGCACTTCTCAACGACAAATGATATATTGGGCCAGCCATTTTCATT
CACCTGACACCATGCAGAAC

Downstream 100 bases:

>100_bases
CCCGCGTCAAGCAGCCAATTTGAAGAGTTGGCGCCGCTTTCGTATCTTTGATATTTTTCATCGCAAGCTCCAGCCATCCA
TGCTCATTCATCAACGCACC

Product: extragenic suppressor protein SuhB

Products: NA

Alternate protein names: I-1-Pase; IMPase; Inositol-1-phosphatase [H]

Number of amino acids: Translated: 264; Mature: 264

Protein sequence:

>264_residues
MNLELQTAVKAAKAAGAITLSRFGELSHREIVAKEYKDFVTEVDKQCEATITATITESFPDDGLLCEEGTSGSGASGRTW
IVDPLDGTLNFIHSFPVFGISIAMRDASGELAVGVVYQPVLDELFTAVKGRGAFLNGKRISVSTREEMQSYLFATGLPFR
DYDHYMDGYIGLLRDVIKDSAGIRRAGSASIDLAYTAAGRFDGFFEYRLFPWDFAAGVLLVREAGGIVTGIAGSDDVFAH
TSILAGSPLTHPLLLEKARRHFGA

Sequences:

>Translated_264_residues
MNLELQTAVKAAKAAGAITLSRFGELSHREIVAKEYKDFVTEVDKQCEATITATITESFPDDGLLCEEGTSGSGASGRTW
IVDPLDGTLNFIHSFPVFGISIAMRDASGELAVGVVYQPVLDELFTAVKGRGAFLNGKRISVSTREEMQSYLFATGLPFR
DYDHYMDGYIGLLRDVIKDSAGIRRAGSASIDLAYTAAGRFDGFFEYRLFPWDFAAGVLLVREAGGIVTGIAGSDDVFAH
TSILAGSPLTHPLLLEKARRHFGA
>Mature_264_residues
MNLELQTAVKAAKAAGAITLSRFGELSHREIVAKEYKDFVTEVDKQCEATITATITESFPDDGLLCEEGTSGSGASGRTW
IVDPLDGTLNFIHSFPVFGISIAMRDASGELAVGVVYQPVLDELFTAVKGRGAFLNGKRISVSTREEMQSYLFATGLPFR
DYDHYMDGYIGLLRDVIKDSAGIRRAGSASIDLAYTAAGRFDGFFEYRLFPWDFAAGVLLVREAGGIVTGIAGSDDVFAH
TSILAGSPLTHPLLLEKARRHFGA

Specific function: Unknown

COG id: COG0483

COG function: function code G; Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the inositol monophosphatase family [H]

Homologues:

Organism=Homo sapiens, GI7657236, Length=261, Percent_Identity=34.0996168582375, Blast_Score=135, Evalue=4e-32,
Organism=Homo sapiens, GI5031789, Length=201, Percent_Identity=31.8407960199005, Blast_Score=120, Evalue=1e-27,
Organism=Homo sapiens, GI221625487, Length=201, Percent_Identity=31.8407960199005, Blast_Score=120, Evalue=1e-27,
Organism=Homo sapiens, GI221625507, Length=113, Percent_Identity=38.0530973451327, Blast_Score=89, Evalue=3e-18,
Organism=Escherichia coli, GI1788882, Length=260, Percent_Identity=44.2307692307692, Blast_Score=205, Evalue=2e-54,
Organism=Caenorhabditis elegans, GI193202570, Length=250, Percent_Identity=29.6, Blast_Score=127, Evalue=4e-30,
Organism=Caenorhabditis elegans, GI193202572, Length=250, Percent_Identity=31.2, Blast_Score=124, Evalue=6e-29,
Organism=Saccharomyces cerevisiae, GI6320493, Length=205, Percent_Identity=39.0243902439024, Blast_Score=128, Evalue=8e-31,
Organism=Saccharomyces cerevisiae, GI6321836, Length=234, Percent_Identity=29.0598290598291, Blast_Score=96, Evalue=6e-21,
Organism=Drosophila melanogaster, GI21357329, Length=250, Percent_Identity=32.8, Blast_Score=140, Evalue=8e-34,
Organism=Drosophila melanogaster, GI24664922, Length=223, Percent_Identity=35.4260089686099, Blast_Score=139, Evalue=2e-33,
Organism=Drosophila melanogaster, GI24664926, Length=248, Percent_Identity=31.8548387096774, Blast_Score=137, Evalue=1e-32,
Organism=Drosophila melanogaster, GI21357303, Length=252, Percent_Identity=29.7619047619048, Blast_Score=125, Evalue=4e-29,
Organism=Drosophila melanogaster, GI21357957, Length=243, Percent_Identity=32.9218106995885, Blast_Score=124, Evalue=7e-29,
Organism=Drosophila melanogaster, GI24664918, Length=223, Percent_Identity=35.4260089686099, Blast_Score=120, Evalue=1e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020583
- InterPro:   IPR000760
- InterPro:   IPR020550
- InterPro:   IPR022337 [H]

Pfam domain/function: PF00459 Inositol_P [H]

EC number: =3.1.3.25 [H]

Molecular weight: Translated: 28515; Mature: 28515

Theoretical pI: Translated: 5.00; Mature: 5.00

Prosite motif: PS00629 IMP_1 ; PS00630 IMP_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNLELQTAVKAAKAAGAITLSRFGELSHREIVAKEYKDFVTEVDKQCEATITATITESFP
CCCCHHHHHHHHHHHCCEEHHHHCCCHHHHHHHHHHHHHHHHHHHHHCEEEEEEEECCCC
DDGLLCEEGTSGSGASGRTWIVDPLDGTLNFIHSFPVFGISIAMRDASGELAVGVVYQPV
CCCEEECCCCCCCCCCCCEEEECCCCHHHHHHHHCCCEEEEEEEECCCCCEEEEHHHHHH
LDELFTAVKGRGAFLNGKRISVSTREEMQSYLFATGLPFRDYDHYMDGYIGLLRDVIKDS
HHHHHHHHCCCCCEECCCEEEECHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCC
AGIRRAGSASIDLAYTAAGRFDGFFEYRLFPWDFAAGVLLVREAGGIVTGIAGSDDVFAH
CCCCCCCCCCEEEEEEECCCCCCEEEEEECCHHHHHHEEEEEECCCEEEECCCCCCHHHH
TSILAGSPLTHPLLLEKARRHFGA
HHHHCCCCCCCHHHHHHHHHHCCC
>Mature Secondary Structure
MNLELQTAVKAAKAAGAITLSRFGELSHREIVAKEYKDFVTEVDKQCEATITATITESFP
CCCCHHHHHHHHHHHCCEEHHHHCCCHHHHHHHHHHHHHHHHHHHHHCEEEEEEEECCCC
DDGLLCEEGTSGSGASGRTWIVDPLDGTLNFIHSFPVFGISIAMRDASGELAVGVVYQPV
CCCEEECCCCCCCCCCCCEEEECCCCHHHHHHHHCCCEEEEEEEECCCCCEEEEHHHHHH
LDELFTAVKGRGAFLNGKRISVSTREEMQSYLFATGLPFRDYDHYMDGYIGLLRDVIKDS
HHHHHHHHCCCCCEECCCEEEECHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCC
AGIRRAGSASIDLAYTAAGRFDGFFEYRLFPWDFAAGVLLVREAGGIVTGIAGSDDVFAH
CCCCCCCCCCEEEEEEECCCCCCEEEEEECCHHHHHHEEEEEECCCEEEECCCCCCHHHH
TSILAGSPLTHPLLLEKARRHFGA
HHHHCCCCCCCHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]