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The map label for this gene is 21674386

Identifier: 21674386

GI number: 21674386

Start: 1477932

End: 1478468

Strand: Reverse

Name: 21674386

Synonym: CT1568

Alternate gene names: NA

Gene position: 1478468-1477932 (Counterclockwise)

Preceding gene: 21674390

Following gene: 21674385

Centisome position: 68.61

GC content: 55.49

Gene sequence:

>537_bases
ATGCCGGTAAGAATACTTTTTGTCTGTTACGAAAATATCTGCCGTTCTCCGATGGCAGAGGGCGCTTTCGGACACGTCGC
ATCGCTGCTCGGGGCCGGTGGTTTTTTTGAAGTCGAATCTGCCGGAACGGTGTGCTACCAGTCGGGCTCTTCACCTGACC
ACCGCGCTGTTCGGGCGGCGGAGCGTTACGGTATCGATATCTCTTCGATCCGTGCGCGTTGTATTCACGACCTCGATCTC
GGAAGCTTTGACCGGATTTTCGTTATGGATGCAGAAAATCATCGTGACGTGCTCGACGCGCTTGACGGTCTGCCGGTGAC
AGTACACATGATGACCGATTTCGCTTTGTCTGATGCGGGCGTGGAAATCGAAGACCCTTATTACGGCAGCGAAGAGGGCT
TCGAGCGGACCATGGAGCGACTGCTGCACAGTGCTACGGGAATTTTGTCAGCCTTGCGGGAGGCATATGAACTGCCCATC
GTCGACAGAGAGGCAGGGGTGTTTTTGCAACACAGTGGGACGGGCGATGGGCGATAG

Upstream 100 bases:

>100_bases
ATATTGTATGGTCTTAAAAAACTGTTTACGTGATAATATGTTACGTTATAACCTCAATTTTGCATGGGTTTGCCGTCCTG
TTTCAATCAAATTTTAAGCC

Downstream 100 bases:

>100_bases
CTTTACCTTCATTTTCAACCCTGCTGCCGACAAGGGGCGCGCCGCCGACAAGACCGCGCTCATCGAGCGCTCGCTCGCAC
ACTTCGAGGTGGCTTCGCTC

Product: protein-tyrosine-phosphatase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 178; Mature: 177

Protein sequence:

>178_residues
MPVRILFVCYENICRSPMAEGAFGHVASLLGAGGFFEVESAGTVCYQSGSSPDHRAVRAAERYGIDISSIRARCIHDLDL
GSFDRIFVMDAENHRDVLDALDGLPVTVHMMTDFALSDAGVEIEDPYYGSEEGFERTMERLLHSATGILSALREAYELPI
VDREAGVFLQHSGTGDGR

Sequences:

>Translated_178_residues
MPVRILFVCYENICRSPMAEGAFGHVASLLGAGGFFEVESAGTVCYQSGSSPDHRAVRAAERYGIDISSIRARCIHDLDL
GSFDRIFVMDAENHRDVLDALDGLPVTVHMMTDFALSDAGVEIEDPYYGSEEGFERTMERLLHSATGILSALREAYELPI
VDREAGVFLQHSGTGDGR
>Mature_177_residues
PVRILFVCYENICRSPMAEGAFGHVASLLGAGGFFEVESAGTVCYQSGSSPDHRAVRAAERYGIDISSIRARCIHDLDLG
SFDRIFVMDAENHRDVLDALDGLPVTVHMMTDFALSDAGVEIEDPYYGSEEGFERTMERLLHSATGILSALREAYELPIV
DREAGVFLQHSGTGDGR

Specific function: Unknown

COG id: COG0394

COG function: function code T; Protein-tyrosine-phosphatase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the low molecular weight phosphotyrosine protein phosphatase family [H]

Homologues:

Organism=Homo sapiens, GI4757714, Length=148, Percent_Identity=32.4324324324324, Blast_Score=86, Evalue=2e-17,
Organism=Homo sapiens, GI6005988, Length=148, Percent_Identity=30.4054054054054, Blast_Score=78, Evalue=5e-15,
Organism=Saccharomyces cerevisiae, GI6325330, Length=153, Percent_Identity=30.718954248366, Blast_Score=81, Evalue=7e-17,
Organism=Drosophila melanogaster, GI78706770, Length=133, Percent_Identity=36.0902255639098, Blast_Score=74, Evalue=4e-14,
Organism=Drosophila melanogaster, GI78706772, Length=133, Percent_Identity=36.0902255639098, Blast_Score=74, Evalue=4e-14,
Organism=Drosophila melanogaster, GI78706766, Length=153, Percent_Identity=32.6797385620915, Blast_Score=70, Evalue=1e-12,
Organism=Drosophila melanogaster, GI78706768, Length=153, Percent_Identity=32.6797385620915, Blast_Score=70, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000106
- InterPro:   IPR017867 [H]

Pfam domain/function: PF01451 LMWPc [H]

EC number: =3.1.3.48 [H]

Molecular weight: Translated: 19462; Mature: 19331

Theoretical pI: Translated: 4.43; Mature: 4.43

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPVRILFVCYENICRSPMAEGAFGHVASLLGAGGFFEVESAGTVCYQSGSSPDHRAVRAA
CCEEEEEEEHHHHHCCCCCCCHHHHHHHHHCCCCCEEECCCCEEEECCCCCCHHHHHHHH
ERYGIDISSIRARCIHDLDLGSFDRIFVMDAENHRDVLDALDGLPVTVHMMTDFALSDAG
HHHCCCHHHHHHHHHHCCCCCCCCEEEEEECCCCHHHHHHHCCCCEEEEEEHHHHHCCCC
VEIEDPYYGSEEGFERTMERLLHSATGILSALREAYELPIVDREAGVFLQHSGTGDGR
CEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEECCCCEEEEECCCCCCC
>Mature Secondary Structure 
PVRILFVCYENICRSPMAEGAFGHVASLLGAGGFFEVESAGTVCYQSGSSPDHRAVRAA
CEEEEEEEHHHHHCCCCCCCHHHHHHHHHCCCCCEEECCCCEEEECCCCCCHHHHHHHH
ERYGIDISSIRARCIHDLDLGSFDRIFVMDAENHRDVLDALDGLPVTVHMMTDFALSDAG
HHHCCCHHHHHHHHHHCCCCCCCCEEEEEECCCCHHHHHHHCCCCEEEEEEHHHHHCCCC
VEIEDPYYGSEEGFERTMERLLHSATGILSALREAYELPIVDREAGVFLQHSGTGDGR
CEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEECCCCEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8590279; 8905231 [H]