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The map label for this gene is aspC-1 [H]

Identifier: 21674065

GI number: 21674065

Start: 1168813

End: 1170027

Strand: Reverse

Name: aspC-1 [H]

Synonym: CT1242

Alternate gene names: 21674065

Gene position: 1170027-1168813 (Counterclockwise)

Preceding gene: 21674066

Following gene: 21674061

Centisome position: 54.29

GC content: 53.99

Gene sequence:

>1215_bases
ATGTTCGACGAGATAGAATTTGACAGGATCAAGAGACTTCCAAAATATGTGTTTGCCGCCGTCAACGAGCTGAAAATGGC
TGAACGTCGGGCAGGGAGGGATGTTATCGATTTTTCGATGGGCAATCCTGACGGACCGACACCCCAGCACATTGTTGACA
AGCTTGTCGAGAGTGTTAGCAAACCCAAGACGCATGGCTATTCGGTTTCGAAGGGGATTTACAAGCTTCGCGGAGCTATC
GGCGGCTGGTACCGCGACAAGTACAATGTCGATCTCGATCTCGACCGCGAGGTGGTGGTAACGATGGGTTCGAAAGAGGG
CTACGTTCATCTGGTGCAGGCGATCACTAATCCGGGCGATCTGGCCATTGTACCCGATCCCTGCTATCCTATTCACTCGC
AGGCGTTCATTCTCGCTGGCGGCAACGTGCATCGCATGAAGCTGGAGATGAACGAGGACTACACGCTCGACGAGGAGGCC
TTTTTTCATAATGTCGAAACCGCTCTTCGCGAATCGTCGCCCAAGCCGAAGTATCTCGTGGTCAACTTCCCGAACAACCC
GACGACGGCTACGGTTGAGCTCCCGTTTTACGAGCGTCTGGTCGAGCTGGCGCGCAGAGAGCGATTTTACATTATCAGTG
ACATTGCCTATGCCGAGATTACCTTCGACGGTTATGTGACTCCCTCTATCCTCCAGGTGTCGGGGGCGAAAGATGTGGCT
GTCGAAAGCTACACGCTTTCAAAGACCTACAACATGGCCGGCTGGCGCATGGGCTTCATGGTCGGTAACGCCAAGCTTGT
CGGTGCTCTCGAAAAAATCAAGAGCTGGCTCGATTATGGCACCTTCACGCCGATCCAGGTTGCCGCGACGATCGCGCTCA
CCGGAGACCAGAGCTGCGTCCGGGAGATCAGGGAGGTGTATCGCAAACGGCGTGACGTGCTCATTTCAAGCTTCGCCAAT
GCAGGTTGGGATATTGTTTCTCCGAAGGCATCGATGTTCGTTTGGGCGAGAATTCCCGAACAGATGCGCGCCATGGGCAG
CCTCGAATTCAGTAAAAAGCTGCTCATCGAAGGCAAGGTTGCGGTCAGCCCCGGTATTGGCTTCGGCACTTATGGCGATG
AGTATGTTCGTGTGGCGATGATCGAGAACGAAGAGCGAATCCGTCAGGCCGCGAGAAATATCAAACGCTTTTTGAAGAAT
AACGCCGGGTCGTGA

Upstream 100 bases:

>100_bases
TAGTTCTTCTATGGAGATCAACAGCATTTTGTTTATGATTGGGTTTGCTTTAATAAAAATTTAGTGTAGCTGTTTCAACG
ATATTCCGAAACCAGAAACC

Downstream 100 bases:

>100_bases
GCGTTTGCAGATTTTGTCGGCAAAGGCATAAAGCAAAAAGGGAGCACTCGCTCCCTTTTTGCTTTTATCTTTTGTGCCGT
TACTCCTCGCTTTCGAACAA

Product: aspartate aminotransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 404; Mature: 404

Protein sequence:

>404_residues
MFDEIEFDRIKRLPKYVFAAVNELKMAERRAGRDVIDFSMGNPDGPTPQHIVDKLVESVSKPKTHGYSVSKGIYKLRGAI
GGWYRDKYNVDLDLDREVVVTMGSKEGYVHLVQAITNPGDLAIVPDPCYPIHSQAFILAGGNVHRMKLEMNEDYTLDEEA
FFHNVETALRESSPKPKYLVVNFPNNPTTATVELPFYERLVELARRERFYIISDIAYAEITFDGYVTPSILQVSGAKDVA
VESYTLSKTYNMAGWRMGFMVGNAKLVGALEKIKSWLDYGTFTPIQVAATIALTGDQSCVREIREVYRKRRDVLISSFAN
AGWDIVSPKASMFVWARIPEQMRAMGSLEFSKKLLIEGKVAVSPGIGFGTYGDEYVRVAMIENEERIRQAARNIKRFLKN
NAGS

Sequences:

>Translated_404_residues
MFDEIEFDRIKRLPKYVFAAVNELKMAERRAGRDVIDFSMGNPDGPTPQHIVDKLVESVSKPKTHGYSVSKGIYKLRGAI
GGWYRDKYNVDLDLDREVVVTMGSKEGYVHLVQAITNPGDLAIVPDPCYPIHSQAFILAGGNVHRMKLEMNEDYTLDEEA
FFHNVETALRESSPKPKYLVVNFPNNPTTATVELPFYERLVELARRERFYIISDIAYAEITFDGYVTPSILQVSGAKDVA
VESYTLSKTYNMAGWRMGFMVGNAKLVGALEKIKSWLDYGTFTPIQVAATIALTGDQSCVREIREVYRKRRDVLISSFAN
AGWDIVSPKASMFVWARIPEQMRAMGSLEFSKKLLIEGKVAVSPGIGFGTYGDEYVRVAMIENEERIRQAARNIKRFLKN
NAGS
>Mature_404_residues
MFDEIEFDRIKRLPKYVFAAVNELKMAERRAGRDVIDFSMGNPDGPTPQHIVDKLVESVSKPKTHGYSVSKGIYKLRGAI
GGWYRDKYNVDLDLDREVVVTMGSKEGYVHLVQAITNPGDLAIVPDPCYPIHSQAFILAGGNVHRMKLEMNEDYTLDEEA
FFHNVETALRESSPKPKYLVVNFPNNPTTATVELPFYERLVELARRERFYIISDIAYAEITFDGYVTPSILQVSGAKDVA
VESYTLSKTYNMAGWRMGFMVGNAKLVGALEKIKSWLDYGTFTPIQVAATIALTGDQSCVREIREVYRKRRDVLISSFAN
AGWDIVSPKASMFVWARIPEQMRAMGSLEFSKKLLIEGKVAVSPGIGFGTYGDEYVRVAMIENEERIRQAARNIKRFLKN
NAGS

Specific function: Unknown

COG id: COG0436

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI95147551, Length=398, Percent_Identity=21.608040201005, Blast_Score=94, Evalue=3e-19,
Organism=Homo sapiens, GI169881279, Length=398, Percent_Identity=21.608040201005, Blast_Score=94, Evalue=3e-19,
Organism=Homo sapiens, GI56713256, Length=403, Percent_Identity=20.3473945409429, Blast_Score=79, Evalue=6e-15,
Organism=Homo sapiens, GI56713254, Length=331, Percent_Identity=20.8459214501511, Blast_Score=79, Evalue=6e-15,
Organism=Homo sapiens, GI7705897, Length=257, Percent_Identity=24.9027237354086, Blast_Score=66, Evalue=7e-11,
Organism=Homo sapiens, GI33469970, Length=257, Percent_Identity=24.9027237354086, Blast_Score=66, Evalue=7e-11,
Organism=Escherichia coli, GI1788722, Length=398, Percent_Identity=57.286432160804, Blast_Score=474, Evalue=1e-135,
Organism=Escherichia coli, GI1786816, Length=375, Percent_Identity=24.5333333333333, Blast_Score=130, Evalue=2e-31,
Organism=Escherichia coli, GI1788627, Length=396, Percent_Identity=27.5252525252525, Blast_Score=110, Evalue=2e-25,
Organism=Escherichia coli, GI1787710, Length=386, Percent_Identity=24.6113989637306, Blast_Score=69, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI17567369, Length=402, Percent_Identity=21.8905472636816, Blast_Score=100, Evalue=3e-21,
Organism=Caenorhabditis elegans, GI71994476, Length=405, Percent_Identity=24.1975308641975, Blast_Score=98, Evalue=6e-21,
Organism=Caenorhabditis elegans, GI71994472, Length=404, Percent_Identity=24.009900990099, Blast_Score=98, Evalue=6e-21,
Organism=Caenorhabditis elegans, GI17567663, Length=392, Percent_Identity=25.2551020408163, Blast_Score=85, Evalue=6e-17,
Organism=Saccharomyces cerevisiae, GI6322401, Length=333, Percent_Identity=24.024024024024, Blast_Score=82, Evalue=2e-16,
Organism=Drosophila melanogaster, GI28573069, Length=396, Percent_Identity=21.7171717171717, Blast_Score=94, Evalue=2e-19,
Organism=Drosophila melanogaster, GI24646114, Length=396, Percent_Identity=21.7171717171717, Blast_Score=94, Evalue=2e-19,
Organism=Drosophila melanogaster, GI28573067, Length=396, Percent_Identity=21.7171717171717, Blast_Score=94, Evalue=2e-19,
Organism=Drosophila melanogaster, GI28573065, Length=396, Percent_Identity=21.7171717171717, Blast_Score=94, Evalue=2e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004839
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: 2.6.1.- [C]

Molecular weight: Translated: 45531; Mature: 45531

Theoretical pI: Translated: 8.14; Mature: 8.14

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFDEIEFDRIKRLPKYVFAAVNELKMAERRAGRDVIDFSMGNPDGPTPQHIVDKLVESVS
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCHHHHHHHHHHHHC
KPKTHGYSVSKGIYKLRGAIGGWYRDKYNVDLDLDREVVVTMGSKEGYVHLVQAITNPGD
CCCCCCCCHHHHHHHHHHHHCCCCCCCCCEEECCCCEEEEEECCCCCHHHEEHHHCCCCC
LAIVPDPCYPIHSQAFILAGGNVHRMKLEMNEDYTLDEEAFFHNVETALRESSPKPKYLV
EEEECCCCCCCCCCEEEEECCCEEEEEEEECCCCCCCHHHHHHHHHHHHHCCCCCCCEEE
VNFPNNPTTATVELPFYERLVELARRERFYIISDIAYAEITFDGYVTPSILQVSGAKDVA
EECCCCCCEEEEECHHHHHHHHHHHCCCEEEEEEEEEEEEEECCCCCCCCEEECCCCCEE
VESYTLSKTYNMAGWRMGFMVGNAKLVGALEKIKSWLDYGTFTPIQVAATIALTGDQSCV
EEEEEECCCCCCCCEEEEEEECCHHHHHHHHHHHHHHHCCCCCCEEEEEEEEEECCHHHH
REIREVYRKRRDVLISSFANAGWDIVSPKASMFVWARIPEQMRAMGSLEFSKKLLIEGKV
HHHHHHHHHHHHHHHHHHHCCCCEEECCCCCEEEEEECCHHHHHHCCHHHCCEEEEECEE
AVSPGIGFGTYGDEYVRVAMIENEERIRQAARNIKRFLKNNAGS
EECCCCCCCCCCCCEEEEEEECCHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MFDEIEFDRIKRLPKYVFAAVNELKMAERRAGRDVIDFSMGNPDGPTPQHIVDKLVESVS
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCHHHHHHHHHHHHC
KPKTHGYSVSKGIYKLRGAIGGWYRDKYNVDLDLDREVVVTMGSKEGYVHLVQAITNPGD
CCCCCCCCHHHHHHHHHHHHCCCCCCCCCEEECCCCEEEEEECCCCCHHHEEHHHCCCCC
LAIVPDPCYPIHSQAFILAGGNVHRMKLEMNEDYTLDEEAFFHNVETALRESSPKPKYLV
EEEECCCCCCCCCCEEEEECCCEEEEEEEECCCCCCCHHHHHHHHHHHHHCCCCCCCEEE
VNFPNNPTTATVELPFYERLVELARRERFYIISDIAYAEITFDGYVTPSILQVSGAKDVA
EECCCCCCEEEEECHHHHHHHHHHHCCCEEEEEEEEEEEEEECCCCCCCCEEECCCCCEE
VESYTLSKTYNMAGWRMGFMVGNAKLVGALEKIKSWLDYGTFTPIQVAATIALTGDQSCV
EEEEEECCCCCCCCEEEEEEECCHHHHHHHHHHHHHHHCCCCCCEEEEEEEEEECCHHHH
REIREVYRKRRDVLISSFANAGWDIVSPKASMFVWARIPEQMRAMGSLEFSKKLLIEGKV
HHHHHHHHHHHHHHHHHHHCCCCEEECCCCCEEEEEECCHHHHHHCCHHHCCEEEEECEE
AVSPGIGFGTYGDEYVRVAMIENEERIRQAARNIKRFLKNNAGS
EECCCCCCCCCCCCEEEEEEECCHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: Pyridoxal Phosphate. [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9205837; 9278503 [H]