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The map label for this gene is argJ

Identifier: 21673936

GI number: 21673936

Start: 1043480

End: 1044694

Strand: Direct

Name: argJ

Synonym: CT1110

Alternate gene names: 21673936

Gene position: 1043480-1044694 (Clockwise)

Preceding gene: 21673935

Following gene: 21673937

Centisome position: 48.42

GC content: 62.96

Gene sequence:

>1215_bases
GTGAGGCCGGTTGTTGCCGATCCCGCTTCGGACGCTGTTTTCTGGCCTGAAGGCTTCACGCTCGCAGGCATCAACTGCGG
CATCAAGCCGACGAGCAAAGATCTGATGCTGATGCTCTGCGACGAACCGGCCAGCACCGCCTCGGTCTTCACAACCAACC
TTTGCTGCGCGGCTCCGGTCGAGCTGTCAAAGGCCGCATTGTCGGCCTCCGGCGGCAAGATGCGGGCCGTCATCTGCAAC
AGCGGCAACGCCAACGCCGCCACCGGCGCGGCAGGAATGCAGAATGCGCGACTGATGGCAGAGTCCACGGCGCAAGCCTT
CGACCTCAACGCAGGCGAGGTGCTGGTCGCCTCCACCGGTGTGATCGGCCAGCAGCTGCCGGTCGAAAAAATCGCCGGTG
CCATGCCCTCGCTGAAGGCGACCTCCGGTTCGACGCAATGGTGTGATGCCGCCGAGGCGATCATGACTACCGACACCTTC
CCGAAGGCGTTCGGGGTTGACGTGAAGCTCTCAGGCGGCACGGCGAGAATCGCGGGCATCGCTAAAGGCTCTGGCATGAT
CTGCCCGAACATGGCCACCATGCTCGCCTTCCTGGGCACCGACGCCACCATCGAACCGGCGCTGTTGCAGGAGCTGCTCG
CGGCAGCGAACGCGGTGAGTTTCAACGCCATCACGGTTGACGGCGACACCAGCACCAACGACATGGCGGCGATCATGGCA
AGCGGCAAAGGGCCTGAAGTACTGCGCGGTTCGGACAACGCACGCCTCTTCGGCGAAGCCTTGCGTTCCGTGATGACCAT
GCTCGCCCAGCTCATCATCGTCGATGGCGAAGGGGCAACCAAGTTCGTCGAACTGCGCGTCACCGGCGCAAAAAGCAACG
AAGAAGCTCGCATGGCGGCAATGACCGTGGCCAACTCGCCACTCGTCAAGACGGCCATCCACGGCGAAGACGCCAACTGG
GGCCGCATCATTGCTGCGGCGGGGCGCTCCGGCGCATCGTTCGTGCAAGAAGAGCTGTCGGTGTACTTCGACGACGAGCC
AATTCTCAAGCCGGGGCTCGATGCCAATTTCTCCGAAGAACGGGCCAAGGAGGTCATGTCGAAGGAGGAGTTCACCATCA
CCCTTTCGCTCGGCAAAGGTGCGGGCAGGGCGACCGTGTGGACCTGCGACCTGAGCCACGGCTACATCGAAATCAACGGC
AGCTATCGCAGCTGA

Upstream 100 bases:

>100_bases
TTTGCTTTAAACATTATCGACTTACACAAGATTGGAACCATTTGAAAAATCGATTGCCGCCGTCAAGCGCCTCGCCAAGA
GAACTGTCTGGCCTGAAGGC

Downstream 100 bases:

>100_bases
CCGGTTTTGCCCATCTTTTCACAAGGACTATTCATGGAAAAAATGTGCAGTGAGTTCCGCCCCGAGGGAAAAAGACCTGA
GCCGGCCATCGGCTACATGC

Product: bifunctional ornithine acetyltransferase/N-acetylglutamate synthase protein

Products: NA

Alternate protein names: Glutamate N-acetyltransferase; Ornithine acetyltransferase; OATase; Ornithine transacetylase; Amino-acid acetyltransferase; N-acetylglutamate synthase; AGS

Number of amino acids: Translated: 404; Mature: 404

Protein sequence:

>404_residues
MRPVVADPASDAVFWPEGFTLAGINCGIKPTSKDLMLMLCDEPASTASVFTTNLCCAAPVELSKAALSASGGKMRAVICN
SGNANAATGAAGMQNARLMAESTAQAFDLNAGEVLVASTGVIGQQLPVEKIAGAMPSLKATSGSTQWCDAAEAIMTTDTF
PKAFGVDVKLSGGTARIAGIAKGSGMICPNMATMLAFLGTDATIEPALLQELLAAANAVSFNAITVDGDTSTNDMAAIMA
SGKGPEVLRGSDNARLFGEALRSVMTMLAQLIIVDGEGATKFVELRVTGAKSNEEARMAAMTVANSPLVKTAIHGEDANW
GRIIAAAGRSGASFVQEELSVYFDDEPILKPGLDANFSEERAKEVMSKEEFTITLSLGKGAGRATVWTCDLSHGYIEING
SYRS

Sequences:

>Translated_404_residues
MRPVVADPASDAVFWPEGFTLAGINCGIKPTSKDLMLMLCDEPASTASVFTTNLCCAAPVELSKAALSASGGKMRAVICN
SGNANAATGAAGMQNARLMAESTAQAFDLNAGEVLVASTGVIGQQLPVEKIAGAMPSLKATSGSTQWCDAAEAIMTTDTF
PKAFGVDVKLSGGTARIAGIAKGSGMICPNMATMLAFLGTDATIEPALLQELLAAANAVSFNAITVDGDTSTNDMAAIMA
SGKGPEVLRGSDNARLFGEALRSVMTMLAQLIIVDGEGATKFVELRVTGAKSNEEARMAAMTVANSPLVKTAIHGEDANW
GRIIAAAGRSGASFVQEELSVYFDDEPILKPGLDANFSEERAKEVMSKEEFTITLSLGKGAGRATVWTCDLSHGYIEING
SYRS
>Mature_404_residues
MRPVVADPASDAVFWPEGFTLAGINCGIKPTSKDLMLMLCDEPASTASVFTTNLCCAAPVELSKAALSASGGKMRAVICN
SGNANAATGAAGMQNARLMAESTAQAFDLNAGEVLVASTGVIGQQLPVEKIAGAMPSLKATSGSTQWCDAAEAIMTTDTF
PKAFGVDVKLSGGTARIAGIAKGSGMICPNMATMLAFLGTDATIEPALLQELLAAANAVSFNAITVDGDTSTNDMAAIMA
SGKGPEVLRGSDNARLFGEALRSVMTMLAQLIIVDGEGATKFVELRVTGAKSNEEARMAAMTVANSPLVKTAIHGEDANW
GRIIAAAGRSGASFVQEELSVYFDDEPILKPGLDANFSEERAKEVMSKEEFTITLSLGKGAGRATVWTCDLSHGYIEING
SYRS

Specific function: Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis:the synthesis of acetylglutamate from glutamate and acetyl-CoA, and of ornithine by transacetylation between acetylornithine and glutamate

COG id: COG1364

COG function: function code E; N-acetylglutamate synthase (N-acetylornithine aminotransferase)

Gene ontology:

Cell location: Cytoplasm (Probable)

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ArgJ family

Homologues:

Organism=Saccharomyces cerevisiae, GI6323707, Length=415, Percent_Identity=40, Blast_Score=266, Evalue=4e-72,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ARGJ_CHLTE (P59611)

Other databases:

- EMBL:   AE006470
- RefSeq:   NP_662001.1
- ProteinModelPortal:   P59611
- SMR:   P59611
- MEROPS:   T05.001
- GeneID:   1006898
- GenomeReviews:   AE006470_GR
- KEGG:   cte:CT1110
- NMPDR:   fig|194439.1.peg.1095
- TIGR:   CT1110
- HOGENOM:   HBG284202
- OMA:   QNRFCAA
- ProtClustDB:   PRK05388
- BioCyc:   CTEP194439:CT_1110-MONOMER
- BRENDA:   2.3.1.1
- BRENDA:   2.3.1.35
- GO:   GO:0005737
- HAMAP:   MF_01106
- InterPro:   IPR002813
- InterPro:   IPR016117
- PANTHER:   PTHR23100
- TIGRFAMs:   TIGR00120

Pfam domain/function: PF01960 ArgJ; SSF56266 Pept_S58_DmpA/Arg_biosyn_ArgJ

EC number: =2.3.1.35; =2.3.1.1

Molecular weight: Translated: 41800; Mature: 41800

Theoretical pI: Translated: 4.50; Mature: 4.50

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
4.5 %Met     (Translated Protein)
6.4 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
4.5 %Met     (Mature Protein)
6.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRPVVADPASDAVFWPEGFTLAGINCGIKPTSKDLMLMLCDEPASTASVFTTNLCCAAPV
CCCCCCCCCCCCEECCCCCEEEEEECCCCCCCCCEEEEEECCCCCCHHHEEECCEEECCH
ELSKAALSASGGKMRAVICNSGNANAATGAAGMQNARLMAESTAQAFDLNAGEVLVASTG
HHHHHHHHCCCCEEEEEEECCCCCCCCCCCCCCCCCEEEHHCCHHHEECCCCCEEEEECC
VIGQQLPVEKIAGAMPSLKATSGSTQWCDAAEAIMTTDTFPKAFGVDVKLSGGTARIAGI
CCCCCCCHHHHHCCCCCCCCCCCCCCHHHHHHHHEECCCCCHHHCEEEEECCCCEEEEEE
AKGSGMICPNMATMLAFLGTDATIEPALLQELLAAANAVSFNAITVDGDTSTNDMAAIMA
ECCCCEECCCHHHHHHHHCCCCCCCHHHHHHHHHHHCCEEEEEEEECCCCCCCCEEEEEE
SGKGPEVLRGSDNARLFGEALRSVMTMLAQLIIVDGEGATKFVELRVTGAKSNEEARMAA
CCCCCCEEECCCCHHHHHHHHHHHHHHHHHEEEECCCCCEEEEEEEEECCCCCCCHHEEE
MTVANSPLVKTAIHGEDANWGRIIAAAGRSGASFVQEELSVYFDDEPILKPGLDANFSEE
EEECCCCEEEEEECCCCCCCCEEEEECCCCCHHHHHHHHHEEECCCCCCCCCCCCCCCHH
RAKEVMSKEEFTITLSLGKGAGRATVWTCDLSHGYIEINGSYRS
HHHHHHCCCEEEEEEEECCCCCCEEEEEEECCCCEEEECCCCCC
>Mature Secondary Structure
MRPVVADPASDAVFWPEGFTLAGINCGIKPTSKDLMLMLCDEPASTASVFTTNLCCAAPV
CCCCCCCCCCCCEECCCCCEEEEEECCCCCCCCCEEEEEECCCCCCHHHEEECCEEECCH
ELSKAALSASGGKMRAVICNSGNANAATGAAGMQNARLMAESTAQAFDLNAGEVLVASTG
HHHHHHHHCCCCEEEEEEECCCCCCCCCCCCCCCCCEEEHHCCHHHEECCCCCEEEEECC
VIGQQLPVEKIAGAMPSLKATSGSTQWCDAAEAIMTTDTFPKAFGVDVKLSGGTARIAGI
CCCCCCCHHHHHCCCCCCCCCCCCCCHHHHHHHHEECCCCCHHHCEEEEECCCCEEEEEE
AKGSGMICPNMATMLAFLGTDATIEPALLQELLAAANAVSFNAITVDGDTSTNDMAAIMA
ECCCCEECCCHHHHHHHHCCCCCCCHHHHHHHHHHHCCEEEEEEEECCCCCCCCEEEEEE
SGKGPEVLRGSDNARLFGEALRSVMTMLAQLIIVDGEGATKFVELRVTGAKSNEEARMAA
CCCCCCEEECCCCHHHHHHHHHHHHHHHHHEEEECCCCCEEEEEEEEECCCCCCCHHEEE
MTVANSPLVKTAIHGEDANWGRIIAAAGRSGASFVQEELSVYFDDEPILKPGLDANFSEE
EEECCCCEEEEEECCCCCCCCEEEEECCCCCHHHHHHHHHEEECCCCCCCCCCCCCCCHH
RAKEVMSKEEFTITLSLGKGAGRATVWTCDLSHGYIEINGSYRS
HHHHHHCCCEEEEEEEECCCCCCEEEEEEECCCCEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12093901