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The map label for this gene is argC

Identifier: 21673935

GI number: 21673935

Start: 1042364

End: 1043389

Strand: Direct

Name: argC

Synonym: CT1109

Alternate gene names: 21673935

Gene position: 1042364-1043389 (Clockwise)

Preceding gene: 21673934

Following gene: 21673936

Centisome position: 48.37

GC content: 59.06

Gene sequence:

>1026_bases
ATGAATCATATCCCGATGCAGAATAAGAAGGTTACGGTTTCGGTCATCGGCGCTTCAGGATATTCAGGAGCCGAGCTGGT
GAAGCTGCTCATGAAGCATCCGGGAATCGTTATCGAAGAGCTTTACGCCCACACCCAGGCGGGCAAGCGCTTTACGGAGC
TGTATCCGTCGATACCCTGCGACAAGACGTTCCAGACCTATGCCGGACAGACCAATAGTGATGTTTACTTGCTCGCTCTC
CCGCATGGCGAGGCGTTACAGCTGGTGCCGGGCATCGTGGCTGCCGGAAAAAAGGTGATCGACCTGTCGGGCGACTTCAG
ACTGAAAAACACCGCCGAGCACAAGCGCTTTTATGGCGGCGACAAGTCGGCGGAGGACGTGCTCCAGTACGGAATGCCAG
AGCTGTTCCGCGACGAAATCGCTGGATCGACAGCAATCAGCAATCCGGGTTGCTACGCCACGAGCATCATCCTCGGCCTT
GCGCCCCTCTTCCTTGGCGGCATGGCGGGGCTCGACGTCGAGTCGGTGAACGTGACAGCGGTTTCCGGCATTTCGGGCGC
GGGTCGAAGCGCGAAGCTCGAACTCTCGTTCTCGGAGATGAGCGGAAACATGCGAGCCTACAAGGTGGGCAAGCACCAGC
ACACGCCCGAGATCATGCAGACACTCGGCACCTCCGTGACCGATCCGTCGTTCCGCTTCGTCTTCACACCGATGATCGCG
CCTTATGTCCGAGGCATCTACTCGGTGCTGAACGTGCGCCTCGCCTCGCCGGTAGCCATGGAGCCGGTCCGCGAGCTGTA
TGCGGGATTCTACGCCAACGCTCCGTTCGTCAGGTTGCGCGACGGCGTAACCGAGGTGAGCCACGTCGCCTACACCAACT
TCTGCGACATCAGTCTCGCTTTCGAAAGCGACGGTTCGCTGGTGATCATCACAGCCATCGACAACCTCGTGAAGGGCGCG
GCGGGTCAGGCGGTGCAGAACATGAACCTGATGCTCGGCTTCGGCGAAACAACTGCTTTGCTTTAA

Upstream 100 bases:

>100_bases
TCGGAAATGCCCTGTTTCTTCATGGAAATAAAGCGTGAATTCACTAACATCCGCTTTCCTGAATATTTATTCACTCTGGT
GCATTCGCATTTAAACCCTG

Downstream 100 bases:

>100_bases
ACATTATCGACTTACACAAGATTGGAACCATTTGAAAAATCGATTGCCGCCGTCAAGCGCCTCGCCAAGAGAACTGTCTG
GCCTGAAGGCGTGAGGCCGG

Product: N-acetyl-gamma-glutamyl-phosphate reductase

Products: NA

Alternate protein names: AGPR; N-acetyl-glutamate semialdehyde dehydrogenase; NAGSA dehydrogenase

Number of amino acids: Translated: 341; Mature: 341

Protein sequence:

>341_residues
MNHIPMQNKKVTVSVIGASGYSGAELVKLLMKHPGIVIEELYAHTQAGKRFTELYPSIPCDKTFQTYAGQTNSDVYLLAL
PHGEALQLVPGIVAAGKKVIDLSGDFRLKNTAEHKRFYGGDKSAEDVLQYGMPELFRDEIAGSTAISNPGCYATSIILGL
APLFLGGMAGLDVESVNVTAVSGISGAGRSAKLELSFSEMSGNMRAYKVGKHQHTPEIMQTLGTSVTDPSFRFVFTPMIA
PYVRGIYSVLNVRLASPVAMEPVRELYAGFYANAPFVRLRDGVTEVSHVAYTNFCDISLAFESDGSLVIITAIDNLVKGA
AGQAVQNMNLMLGFGETTALL

Sequences:

>Translated_341_residues
MNHIPMQNKKVTVSVIGASGYSGAELVKLLMKHPGIVIEELYAHTQAGKRFTELYPSIPCDKTFQTYAGQTNSDVYLLAL
PHGEALQLVPGIVAAGKKVIDLSGDFRLKNTAEHKRFYGGDKSAEDVLQYGMPELFRDEIAGSTAISNPGCYATSIILGL
APLFLGGMAGLDVESVNVTAVSGISGAGRSAKLELSFSEMSGNMRAYKVGKHQHTPEIMQTLGTSVTDPSFRFVFTPMIA
PYVRGIYSVLNVRLASPVAMEPVRELYAGFYANAPFVRLRDGVTEVSHVAYTNFCDISLAFESDGSLVIITAIDNLVKGA
AGQAVQNMNLMLGFGETTALL
>Mature_341_residues
MNHIPMQNKKVTVSVIGASGYSGAELVKLLMKHPGIVIEELYAHTQAGKRFTELYPSIPCDKTFQTYAGQTNSDVYLLAL
PHGEALQLVPGIVAAGKKVIDLSGDFRLKNTAEHKRFYGGDKSAEDVLQYGMPELFRDEIAGSTAISNPGCYATSIILGL
APLFLGGMAGLDVESVNVTAVSGISGAGRSAKLELSFSEMSGNMRAYKVGKHQHTPEIMQTLGTSVTDPSFRFVFTPMIA
PYVRGIYSVLNVRLASPVAMEPVRELYAGFYANAPFVRLRDGVTEVSHVAYTNFCDISLAFESDGSLVIITAIDNLVKGA
AGQAVQNMNLMLGFGETTALL

Specific function: Arginine biosynthesis; third step. [C]

COG id: COG0002

COG function: function code E; Acetylglutamate semialdehyde dehydrogenase

Gene ontology:

Cell location: Cytoplasm (Probable)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NAGSA dehydrogenase family. Type 1 subfamily

Homologues:

Organism=Escherichia coli, GI1790396, Length=340, Percent_Identity=35.8823529411765, Blast_Score=183, Evalue=1e-47,
Organism=Saccharomyces cerevisiae, GI6320913, Length=339, Percent_Identity=29.2035398230088, Blast_Score=119, Evalue=6e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ARGC_CHLTE (Q8KDE3)

Other databases:

- EMBL:   AE006470
- RefSeq:   NP_662000.1
- ProteinModelPortal:   Q8KDE3
- SMR:   Q8KDE3
- GeneID:   1006899
- GenomeReviews:   AE006470_GR
- KEGG:   cte:CT1109
- NMPDR:   fig|194439.1.peg.1094
- TIGR:   CT1109
- HOGENOM:   HBG294213
- OMA:   VCRIAVH
- ProtClustDB:   PRK00436
- BioCyc:   CTEP194439:CT_1109-MONOMER
- BRENDA:   1.2.1.38
- GO:   GO:0005737
- HAMAP:   MF_00150
- InterPro:   IPR023013
- InterPro:   IPR000706
- InterPro:   IPR016040
- InterPro:   IPR000534
- InterPro:   IPR012280
- Gene3D:   G3DSA:3.40.50.720
- SMART:   SM00859
- TIGRFAMs:   TIGR01850

Pfam domain/function: PF01118 Semialdhyde_dh; PF02774 Semialdhyde_dhC

EC number: =1.2.1.38

Molecular weight: Translated: 36614; Mature: 36614

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: PS01224 ARGC

Important sites: ACT_SITE 151-151

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNHIPMQNKKVTVSVIGASGYSGAELVKLLMKHPGIVIEELYAHTQAGKRFTELYPSIPC
CCCCCCCCCEEEEEEEECCCCCHHHHHHHHHHCCCHHHHHHHHHHHHCHHHHHHCCCCCC
DKTFQTYAGQTNSDVYLLALPHGEALQLVPGIVAAGKKVIDLSGDFRLKNTAEHKRFYGG
CCCHHHHCCCCCCCEEEEEECCCCHHHHHHHHHHCCCEEEECCCCEEECCCHHHHHHCCC
DKSAEDVLQYGMPELFRDEIAGSTAISNPGCYATSIILGLAPLFLGGMAGLDVESVNVTA
CCCHHHHHHHCCHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCEECEEEEE
VSGISGAGRSAKLELSFSEMSGNMRAYKVGKHQHTPEIMQTLGTSVTDPSFRFVFTPMIA
ECCCCCCCCCEEEEEEHHHHCCCEEEEECCCCCCCHHHHHHHCCCCCCCCCEEEEHHHHH
PYVRGIYSVLNVRLASPVAMEPVRELYAGFYANAPFVRLRDGVTEVSHVAYTNFCDISLA
HHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCEEEECCCHHHHHHHHCCCEEEEEEE
FESDGSLVIITAIDNLVKGAAGQAVQNMNLMLGFGETTALL
EECCCCEEEEEEHHHHHHCCCCHHHHCCEEEEECCCHHHCC
>Mature Secondary Structure
MNHIPMQNKKVTVSVIGASGYSGAELVKLLMKHPGIVIEELYAHTQAGKRFTELYPSIPC
CCCCCCCCCEEEEEEEECCCCCHHHHHHHHHHCCCHHHHHHHHHHHHCHHHHHHCCCCCC
DKTFQTYAGQTNSDVYLLALPHGEALQLVPGIVAAGKKVIDLSGDFRLKNTAEHKRFYGG
CCCHHHHCCCCCCCEEEEEECCCCHHHHHHHHHHCCCEEEECCCCEEECCCHHHHHHCCC
DKSAEDVLQYGMPELFRDEIAGSTAISNPGCYATSIILGLAPLFLGGMAGLDVESVNVTA
CCCHHHHHHHCCHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCEECEEEEE
VSGISGAGRSAKLELSFSEMSGNMRAYKVGKHQHTPEIMQTLGTSVTDPSFRFVFTPMIA
ECCCCCCCCCEEEEEEHHHHCCCEEEEECCCCCCCHHHHHHHCCCCCCCCCEEEEHHHHH
PYVRGIYSVLNVRLASPVAMEPVRELYAGFYANAPFVRLRDGVTEVSHVAYTNFCDISLA
HHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCEEEECCCHHHHHHHHCCCEEEEEEE
FESDGSLVIITAIDNLVKGAAGQAVQNMNLMLGFGETTALL
EECCCCEEEEEEHHHHHHCCCCHHHHCCEEEEECCCHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12093901