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The map label for this gene is recD [H]

Identifier: 21673896

GI number: 21673896

Start: 1009840

End: 1011573

Strand: Direct

Name: recD [H]

Synonym: CT1070

Alternate gene names: 21673896

Gene position: 1009840-1011573 (Clockwise)

Preceding gene: 21673895

Following gene: 21673897

Centisome position: 46.86

GC content: 64.3

Gene sequence:

>1734_bases
ATGATCGACTTCATAGAACGGCCCATCGACTGGCAGGCAGCGGCATTTCTCTGCCGGGGTGTGACGGAGAACGCGGAGTT
GCTGCGCACAGTGGTTTCGCTGCTGAGTCAGGCGGTGGGGCAGGGGCATGTCTGCCTCGATCTGGAGGAAATTGCCGAAG
AGCTCGTGCGAATTCCCGAACGCGAGGAGCCGCTGCGCCTCCTGCCCGACGTTGCAAGCCTCATCGCTGCGCTGCGCTCG
CTGCCCACGCTTGGTGGGCCAGGGGAGCATTGCCCGTTGATTCTCGACGCCGCCGGACGGCTCTACCTCTACCGCTATTT
CCGTTACGAAACACTGCTTGCCGAAGCCATTCGCGCCCGCGCTGCGTCGGTGAGCCTCGAAATCGACGAAGCCGCGCTTG
CTGCACGGCTCGACCGCTACTTCGGTGTCGATAAATCCGGCGAGGATCGCCAGCGGCAGGCCGCACTGGCGGCGCTCCGG
CGGCACTTCTCGGTCATCTCCGGCGGCCCCGGCACCGGCAAGACCACCACCGTCGTGCGCATCCTCGGCCTGTTGCTCGA
ACAGCCAGGCGAAGCACGGATGCGTATCGCGATGGCCGCTCCTACCGGCAAAGCCGCCGCACGGCTCGCGTCGTCCATCA
CCTCGCTTCGGGAAGCGCTACCGTGCGCAGACGAGGTGAAACGCGCGATTCCAAGCCAGGTCACGACGATCCACCGCCTG
CTCGGCACCATTCCCGGCTCGACCGGCTTTCGCCACAACGAGCGCAACCCGCTGCCTTGCGATGTGGTGATCGTCGATGA
AGCCTCGATGGTCGATCTGCCGCTCATGACCGCGCTTGTCACGGCGCTCCCGCCGCACGCCCGGCTCATCCTCATTGGCG
ACCGTGACCAGCTCGCCTCGGTCGAAGCCGGAGCGGTGCTCGGCGACATCTGCTGCGCCGCCGAATCGCCCGTCTCCTTC
ATCGCCGGATGCGTCACCGTGCTCGACCGCAACTACCGCTTCGGCGACGGCTCCGGCATCGCCGCCCTCAGCCGCGCCGT
CAACGCAGGCGACCACAGCGAAGCCTTGCGCCTCTTCGCCGACTCCGGCAGCGGCATTGCTCTCGAAGCCACGCCGACGC
GCGAAACGATCAAAAAGCGCCTCGTCGCCCCGGTACTCGAAGGGTTTCGCCCTTGCCTCGAAGCCAAAACTCCCGCCGAA
GCCCTGCGTCTCTTCGACCGCTTCCGCATCCTCACCGCCCTTCGCGAAGGCCCGTGGGGAGCCAGCGGCATCAACCACGC
CGCCGAAACTTTCCTGAACGAAGCCGGACTCATTCGCCTCGATAGCCAGTTTTACCGGGGTCGCCCCGTGCTCGTCACCG
AAAACGACTACAACCACAAACTCTTCAACGGCGACACCGGCATCATGCTGCCCGACCCGGAAACCGGCAACCTCCGAGCC
TTCTTCGCCGCCCCCGACGGCACCGTCCGCGCCATTCCGCCAGAGTTTCTGCCCAAGCACGAAACCGCATTCGCGATGAC
CGTGCACAAAAGCCAGGGATCAGAATTCGACAGGGTTTTGATGGTTCTGCCTCCGGAGGATTCTGTTTTACTGACGAGAG
AGTTGATTTATACGGGGATCACGCGGGCGAAGCAGTCGGTGACAATCTGGAGCGATGCGGCTGTTTTTTCAGCTGCGGTA
AAGCGCCGGACGGAGCGGAGGAGCGGGTTGAGGGAGAGGTTGGTAAACAGCTAA

Upstream 100 bases:

>100_bases
GCGGCGAAGCGTTCGGGTTTTATCGCGACCTGCCATCTGCGGAGTTGATCCGCGAGCTGAGCGAACTGCTTGTCGAAATG
ACACCAGGGGAGGGCGAAGA

Downstream 100 bases:

>100_bases
TGATTGTTGATGAAGCGAGTTAATGAGACTAAATCGCGTATAAATAACATGAACTTACCGAAACGAATTGAATCTAAAGG
GCGCCTCTAAAAAGGGTGCA

Product: exodeoxyribonuclease V, alpha subunit

Products: NA

Alternate protein names: Exodeoxyribonuclease V 67 kDa polypeptide [H]

Number of amino acids: Translated: 577; Mature: 577

Protein sequence:

>577_residues
MIDFIERPIDWQAAAFLCRGVTENAELLRTVVSLLSQAVGQGHVCLDLEEIAEELVRIPEREEPLRLLPDVASLIAALRS
LPTLGGPGEHCPLILDAAGRLYLYRYFRYETLLAEAIRARAASVSLEIDEAALAARLDRYFGVDKSGEDRQRQAALAALR
RHFSVISGGPGTGKTTTVVRILGLLLEQPGEARMRIAMAAPTGKAAARLASSITSLREALPCADEVKRAIPSQVTTIHRL
LGTIPGSTGFRHNERNPLPCDVVIVDEASMVDLPLMTALVTALPPHARLILIGDRDQLASVEAGAVLGDICCAAESPVSF
IAGCVTVLDRNYRFGDGSGIAALSRAVNAGDHSEALRLFADSGSGIALEATPTRETIKKRLVAPVLEGFRPCLEAKTPAE
ALRLFDRFRILTALREGPWGASGINHAAETFLNEAGLIRLDSQFYRGRPVLVTENDYNHKLFNGDTGIMLPDPETGNLRA
FFAAPDGTVRAIPPEFLPKHETAFAMTVHKSQGSEFDRVLMVLPPEDSVLLTRELIYTGITRAKQSVTIWSDAAVFSAAV
KRRTERRSGLRERLVNS

Sequences:

>Translated_577_residues
MIDFIERPIDWQAAAFLCRGVTENAELLRTVVSLLSQAVGQGHVCLDLEEIAEELVRIPEREEPLRLLPDVASLIAALRS
LPTLGGPGEHCPLILDAAGRLYLYRYFRYETLLAEAIRARAASVSLEIDEAALAARLDRYFGVDKSGEDRQRQAALAALR
RHFSVISGGPGTGKTTTVVRILGLLLEQPGEARMRIAMAAPTGKAAARLASSITSLREALPCADEVKRAIPSQVTTIHRL
LGTIPGSTGFRHNERNPLPCDVVIVDEASMVDLPLMTALVTALPPHARLILIGDRDQLASVEAGAVLGDICCAAESPVSF
IAGCVTVLDRNYRFGDGSGIAALSRAVNAGDHSEALRLFADSGSGIALEATPTRETIKKRLVAPVLEGFRPCLEAKTPAE
ALRLFDRFRILTALREGPWGASGINHAAETFLNEAGLIRLDSQFYRGRPVLVTENDYNHKLFNGDTGIMLPDPETGNLRA
FFAAPDGTVRAIPPEFLPKHETAFAMTVHKSQGSEFDRVLMVLPPEDSVLLTRELIYTGITRAKQSVTIWSDAAVFSAAV
KRRTERRSGLRERLVNS
>Mature_577_residues
MIDFIERPIDWQAAAFLCRGVTENAELLRTVVSLLSQAVGQGHVCLDLEEIAEELVRIPEREEPLRLLPDVASLIAALRS
LPTLGGPGEHCPLILDAAGRLYLYRYFRYETLLAEAIRARAASVSLEIDEAALAARLDRYFGVDKSGEDRQRQAALAALR
RHFSVISGGPGTGKTTTVVRILGLLLEQPGEARMRIAMAAPTGKAAARLASSITSLREALPCADEVKRAIPSQVTTIHRL
LGTIPGSTGFRHNERNPLPCDVVIVDEASMVDLPLMTALVTALPPHARLILIGDRDQLASVEAGAVLGDICCAAESPVSF
IAGCVTVLDRNYRFGDGSGIAALSRAVNAGDHSEALRLFADSGSGIALEATPTRETIKKRLVAPVLEGFRPCLEAKTPAE
ALRLFDRFRILTALREGPWGASGINHAAETFLNEAGLIRLDSQFYRGRPVLVTENDYNHKLFNGDTGIMLPDPETGNLRA
FFAAPDGTVRAIPPEFLPKHETAFAMTVHKSQGSEFDRVLMVLPPEDSVLLTRELIYTGITRAKQSVTIWSDAAVFSAAV
KRRTERRSGLRERLVNS

Specific function: Exhibits several catalytic activities, including ATP- dependent exonuclease, ATP-stimulated endonuclease, ATP-dependent unwinding and DNA-dependent ATPase activities. Strand cleavage occurs 5' to 3' during the unwinding of duplex DNA at CHI sequences, whi

COG id: COG0507

COG function: function code L; ATP-dependent exoDNAse (exonuclease V), alpha subunit - helicase superfamily I member

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the recD family [H]

Homologues:

Organism=Escherichia coli, GI1789182, Length=601, Percent_Identity=40.765391014975, Blast_Score=366, Evalue=1e-102,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR007807
- InterPro:   IPR006344
- InterPro:   IPR000606 [H]

Pfam domain/function: PF05127 DUF699; PF01443 Viral_helicase1 [H]

EC number: =3.1.11.5 [H]

Molecular weight: Translated: 62658; Mature: 62658

Theoretical pI: Translated: 6.59; Mature: 6.59

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIDFIERPIDWQAAAFLCRGVTENAELLRTVVSLLSQAVGQGHVCLDLEEIAEELVRIPE
CCCCCCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHCCC
REEPLRLLPDVASLIAALRSLPTLGGPGEHCPLILDAAGRLYLYRYFRYETLLAEAIRAR
CCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHH
AASVSLEIDEAALAARLDRYFGVDKSGEDRQRQAALAALRRHFSVISGGPGTGKTTTVVR
HHHEEEEEHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHH
ILGLLLEQPGEARMRIAMAAPTGKAAARLASSITSLREALPCADEVKRAIPSQVTTIHRL
HHHHHHCCCCCHHEEEEEECCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHH
LGTIPGSTGFRHNERNPLPCDVVIVDEASMVDLPLMTALVTALPPHARLILIGDRDQLAS
HHCCCCCCCCCCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHCCCCCEEEEEECCHHHHH
VEAGAVLGDICCAAESPVSFIAGCVTVLDRNYRFGDGSGIAALSRAVNAGDHSEALRLFA
HHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHCCCCHHHHHHHEE
DSGSGIALEATPTRETIKKRLVAPVLEGFRPCLEAKTPAEALRLFDRFRILTALREGPWG
CCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCC
ASGINHAAETFLNEAGLIRLDSQFYRGRPVLVTENDYNHKLFNGDTGIMLPDPETGNLRA
CCHHHHHHHHHHCCCCEEEECHHHHCCCCEEEECCCCCCEEECCCCCEECCCCCCCCEEE
FFAAPDGTVRAIPPEFLPKHETAFAMTVHKSQGSEFDRVLMVLPPEDSVLLTRELIYTGI
EEECCCCCEECCCHHHCCCCCCEEEEEEECCCCCCCCEEEEEECCCCCCHHHHHHHHHHH
TRAKQSVTIWSDAAVFSAAVKRRTERRSGLRERLVNS
HHHCCCEEEECHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MIDFIERPIDWQAAAFLCRGVTENAELLRTVVSLLSQAVGQGHVCLDLEEIAEELVRIPE
CCCCCCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHCCC
REEPLRLLPDVASLIAALRSLPTLGGPGEHCPLILDAAGRLYLYRYFRYETLLAEAIRAR
CCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHH
AASVSLEIDEAALAARLDRYFGVDKSGEDRQRQAALAALRRHFSVISGGPGTGKTTTVVR
HHHEEEEEHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHH
ILGLLLEQPGEARMRIAMAAPTGKAAARLASSITSLREALPCADEVKRAIPSQVTTIHRL
HHHHHHCCCCCHHEEEEEECCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHH
LGTIPGSTGFRHNERNPLPCDVVIVDEASMVDLPLMTALVTALPPHARLILIGDRDQLAS
HHCCCCCCCCCCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHCCCCCEEEEEECCHHHHH
VEAGAVLGDICCAAESPVSFIAGCVTVLDRNYRFGDGSGIAALSRAVNAGDHSEALRLFA
HHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHCCCCHHHHHHHEE
DSGSGIALEATPTRETIKKRLVAPVLEGFRPCLEAKTPAEALRLFDRFRILTALREGPWG
CCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCC
ASGINHAAETFLNEAGLIRLDSQFYRGRPVLVTENDYNHKLFNGDTGIMLPDPETGNLRA
CCHHHHHHHHHHCCCCEEEECHHHHCCCCEEEECCCCCCEEECCCCCEECCCCCCCCEEE
FFAAPDGTVRAIPPEFLPKHETAFAMTVHKSQGSEFDRVLMVLPPEDSVLLTRELIYTGI
EEECCCCCEECCCHHHCCCCCCEEEEEEECCCCCCCCEEEEEECCCCCCHHHHHHHHHHH
TRAKQSVTIWSDAAVFSAAVKRRTERRSGLRERLVNS
HHHCCCEEEECHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 3537961; 9278503; 3537960 [H]