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The map label for this gene is guaD [H]

Identifier: 21673822

GI number: 21673822

Start: 944473

End: 945057

Strand: Direct

Name: guaD [H]

Synonym: CT0994

Alternate gene names: 21673822

Gene position: 944473-945057 (Clockwise)

Preceding gene: 21673821

Following gene: 21673825

Centisome position: 43.83

GC content: 59.49

Gene sequence:

>585_bases
ATGTCCTACCAACCCAGCCACATACGCTTTTCACTCCCCGAATGGCTGGAGAGCTATTGCGGCACTTACCAGCCGTCAGC
TTCGCTCGAAGCGCGGATGCGGTTTGTCGTCGGGGCGTCGCGGAAAAGTGTCGAGGAGGTGAGCGGCGGGCCGTTTGCGG
CTGCGGTGTTTGAGATCGAGTCGGGAAGGCTTGTCTCGCTTGGCGTCAATCTGGTGCTCACTCAGAACTCATCAATCCTC
CATGCTGAAATGGTCGCCATTGTGCTCGCGCAAATGAAACTCGGCGCGTACGATCTTGGCGGCTTCGGTATGCCTGCGCA
TGAGCTGGTGACGAGCACCGAGCCGTGCGTGATGTGTTTCGGCGCAGTACTCTGGTCGGGCGTTCGGCACCTGGCGACCG
GGGCGCTTTCCGAGGATGCTCGGGCAATTGGATTCGACGAGGGGCCAAAACCGGAAAAATGGATAGAGGAACTCGAAGCC
CGAGGCATTCGCGTTACCACCGGTGTGGAGCGGGATACGGCTCGCGATGTGTTGCAGCTCTACGCTCGCATGGGCGGACA
GATTTATAACGCCCGAAAAGGCTGA

Upstream 100 bases:

>100_bases
TGTGCATGAGTTCATGAATAAATTGAAATCATTATTTAACCCTTAGCCGAACTGAATAATAAAGTCGTAATAGCTAAGCC
GTAGAACTCCGAAAACGCAC

Downstream 100 bases:

>100_bases
CGGCGGGCGCAGTATGCCAGACAAGCGATTCCGCGGGTATTGAGCAGAAAAGCATTTTAGCAGAAGTTTGCCGGATTTGG
AAGGGATATTGTCCCCGATG

Product: cytidine and deoxycytidylate deaminase family protein

Products: NA

Alternate protein names: GDEase; Guanase; Guanine aminase; Guanine aminohydrolase; GAH [H]

Number of amino acids: Translated: 194; Mature: 193

Protein sequence:

>194_residues
MSYQPSHIRFSLPEWLESYCGTYQPSASLEARMRFVVGASRKSVEEVSGGPFAAAVFEIESGRLVSLGVNLVLTQNSSIL
HAEMVAIVLAQMKLGAYDLGGFGMPAHELVTSTEPCVMCFGAVLWSGVRHLATGALSEDARAIGFDEGPKPEKWIEELEA
RGIRVTTGVERDTARDVLQLYARMGGQIYNARKG

Sequences:

>Translated_194_residues
MSYQPSHIRFSLPEWLESYCGTYQPSASLEARMRFVVGASRKSVEEVSGGPFAAAVFEIESGRLVSLGVNLVLTQNSSIL
HAEMVAIVLAQMKLGAYDLGGFGMPAHELVTSTEPCVMCFGAVLWSGVRHLATGALSEDARAIGFDEGPKPEKWIEELEA
RGIRVTTGVERDTARDVLQLYARMGGQIYNARKG
>Mature_193_residues
SYQPSHIRFSLPEWLESYCGTYQPSASLEARMRFVVGASRKSVEEVSGGPFAAAVFEIESGRLVSLGVNLVLTQNSSILH
AEMVAIVLAQMKLGAYDLGGFGMPAHELVTSTEPCVMCFGAVLWSGVRHLATGALSEDARAIGFDEGPKPEKWIEELEAR
GIRVTTGVERDTARDVLQLYARMGGQIYNARKG

Specific function: Catalyzes the hydrolytic deamination of guanine, producing xanthine and ammonia [H]

COG id: COG0590

COG function: function code FJ; Cytosine/adenosine deaminases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cytidine and deoxycytidylate deaminase family [H]

Homologues:

Organism=Caenorhabditis elegans, GI17555996, Length=116, Percent_Identity=39.6551724137931, Blast_Score=80, Evalue=7e-16,
Organism=Caenorhabditis elegans, GI17554608, Length=151, Percent_Identity=31.1258278145695, Blast_Score=79, Evalue=1e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016192
- InterPro:   IPR002125
- InterPro:   IPR016193 [H]

Pfam domain/function: PF00383 dCMP_cyt_deam_1 [H]

EC number: =3.5.4.3 [H]

Molecular weight: Translated: 21084; Mature: 20953

Theoretical pI: Translated: 5.68; Mature: 5.68

Prosite motif: PS00903 CYT_DCMP_DEAMINASES

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSYQPSHIRFSLPEWLESYCGTYQPSASLEARMRFVVGASRKSVEEVSGGPFAAAVFEIE
CCCCCCCEEECCHHHHHHHCCCCCCCCCHHHHHHHHHCCCHHHHHHHCCCCEEEEEEEEC
SGRLVSLGVNLVLTQNSSILHAEMVAIVLAQMKLGAYDLGGFGMPAHELVTSTEPCVMCF
CCEEEEECEEEEEECCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHCCCCHHHHHH
GAVLWSGVRHLATGALSEDARAIGFDEGPKPEKWIEELEARGIRVTTGVERDTARDVLQL
HHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHCCEEEECCCCHHHHHHHHHH
YARMGGQIYNARKG
HHHHCCCCCCCCCC
>Mature Secondary Structure 
SYQPSHIRFSLPEWLESYCGTYQPSASLEARMRFVVGASRKSVEEVSGGPFAAAVFEIE
CCCCCCEEECCHHHHHHHCCCCCCCCCHHHHHHHHHCCCHHHHHHHCCCCEEEEEEEEC
SGRLVSLGVNLVLTQNSSILHAEMVAIVLAQMKLGAYDLGGFGMPAHELVTSTEPCVMCF
CCEEEEECEEEEEECCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHCCCCHHHHHH
GAVLWSGVRHLATGALSEDARAIGFDEGPKPEKWIEELEARGIRVTTGVERDTARDVLQL
HHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHCCEEEECCCCHHHHHHHHHH
YARMGGQIYNARKG
HHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377; 11101664 [H]