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The map label for this gene is coaD

Identifier: 21673793

GI number: 21673793

Start: 909557

End: 910054

Strand: Direct

Name: coaD

Synonym: CT0965

Alternate gene names: 21673793

Gene position: 909557-910054 (Clockwise)

Preceding gene: 21673792

Following gene: 21673794

Centisome position: 42.21

GC content: 55.42

Gene sequence:

>498_bases
ATGAGTAAGAAAGCCATCTATCCGGGGACCTTCGATCCCTTCACCAACGGCCATCTCGATGTGCTCGAGCGCGCGCTGAA
CATTTTTGAACATGTTGACGTGGTGCTTGCCGAGAACAGTCAGAAGCAGACCCTTTTTTCGGTTGAAGAGCGATTCGACA
TGGTCAGGGAGGTGGTTCGTGACCTTCCAAACGTGAGTGTCGATGTGTTGCGCGAGGGGCTTCTTGCCGACTACGCCCGG
CAGGCGGGGGCCAGCGCTATTGTCAGGGGCGTGCGGCAGGTGAAGGATTTCGAGTATGAGTTCCAGATGTCGCTCTTGAA
CCGTCACCTCTATCCCGAAGTGACTACGGTGTTTCTCATGCCGAACGTCAAATACACCTATGTCGCTTCGACGATTATCC
GCGAGGTCTCAATGCTCGGCGGCGATGTCAGCAAGTTTGTCCATCCCTACGTGCTCGACCAACTTTCGCGAAAAAGAGCG
GAACGGCGGGCGCACTGA

Upstream 100 bases:

>100_bases
CATCACGCGAGTCATGATTTTTCGCAATCTCGCGGGTATCTCTTCCACAAGGATTACGGCACGACCCGAGTCTCGTTTTT
TACACCACAACCTGAAGCGC

Downstream 100 bases:

>100_bases
TTTTTTTCAATTAACAACCAATTCTGCAAAGATGAGCGTAGAGAGCTTTGAACGATTCCTGAGCCGCCGGGTGCTGAGCA
TGCAGGAGTCGCAGACGATG

Product: phosphopantetheine adenylyltransferase

Products: NA

Alternate protein names: Dephospho-CoA pyrophosphorylase; Pantetheine-phosphate adenylyltransferase; PPAT

Number of amino acids: Translated: 165; Mature: 164

Protein sequence:

>165_residues
MSKKAIYPGTFDPFTNGHLDVLERALNIFEHVDVVLAENSQKQTLFSVEERFDMVREVVRDLPNVSVDVLREGLLADYAR
QAGASAIVRGVRQVKDFEYEFQMSLLNRHLYPEVTTVFLMPNVKYTYVASTIIREVSMLGGDVSKFVHPYVLDQLSRKRA
ERRAH

Sequences:

>Translated_165_residues
MSKKAIYPGTFDPFTNGHLDVLERALNIFEHVDVVLAENSQKQTLFSVEERFDMVREVVRDLPNVSVDVLREGLLADYAR
QAGASAIVRGVRQVKDFEYEFQMSLLNRHLYPEVTTVFLMPNVKYTYVASTIIREVSMLGGDVSKFVHPYVLDQLSRKRA
ERRAH
>Mature_164_residues
SKKAIYPGTFDPFTNGHLDVLERALNIFEHVDVVLAENSQKQTLFSVEERFDMVREVVRDLPNVSVDVLREGLLADYARQ
AGASAIVRGVRQVKDFEYEFQMSLLNRHLYPEVTTVFLMPNVKYTYVASTIIREVSMLGGDVSKFVHPYVLDQLSRKRAE
RRAH

Specific function: Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate

COG id: COG0669

COG function: function code H; Phosphopantetheine adenylyltransferase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial CoaD family

Homologues:

Organism=Escherichia coli, GI1790065, Length=160, Percent_Identity=43.125, Blast_Score=149, Evalue=6e-38,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): COAD_CHLTE (Q8KDS9)

Other databases:

- EMBL:   AE006470
- RefSeq:   NP_661858.1
- ProteinModelPortal:   Q8KDS9
- SMR:   Q8KDS9
- GeneID:   1007071
- GenomeReviews:   AE006470_GR
- KEGG:   cte:CT0965
- NMPDR:   fig|194439.1.peg.952
- TIGR:   CT0965
- HOGENOM:   HBG288308
- OMA:   VRQIAAM
- ProtClustDB:   PRK00168
- BioCyc:   CTEP194439:CT_0965-MONOMER
- BRENDA:   2.7.7.3
- GO:   GO:0005737
- HAMAP:   MF_00151
- InterPro:   IPR004821
- InterPro:   IPR004820
- InterPro:   IPR001980
- InterPro:   IPR014729
- Gene3D:   G3DSA:3.40.50.620
- PRINTS:   PR01020
- TIGRFAMs:   TIGR01510
- TIGRFAMs:   TIGR00125

Pfam domain/function: PF01467 CTP_transf_2

EC number: =2.7.7.3

Molecular weight: Translated: 18964; Mature: 18833

Theoretical pI: Translated: 7.09; Mature: 7.09

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKKAIYPGTFDPFTNGHLDVLERALNIFEHVDVVLAENSQKQTLFSVEERFDMVREVVR
CCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHH
DLPNVSVDVLREGLLADYARQAGASAIVRGVRQVKDFEYEFQMSLLNRHLYPEVTTVFLM
HCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHEEEC
PNVKYTYVASTIIREVSMLGGDVSKFVHPYVLDQLSRKRAERRAH
CCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SKKAIYPGTFDPFTNGHLDVLERALNIFEHVDVVLAENSQKQTLFSVEERFDMVREVVR
CCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHH
DLPNVSVDVLREGLLADYARQAGASAIVRGVRQVKDFEYEFQMSLLNRHLYPEVTTVFLM
HCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHEEEC
PNVKYTYVASTIIREVSMLGGDVSKFVHPYVLDQLSRKRAERRAH
CCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12093901