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The map label for this gene is tktB [C]

Identifier: 21673791

GI number: 21673791

Start: 908082

End: 908993

Strand: Direct

Name: tktB [C]

Synonym: CT0963

Alternate gene names: 21673791

Gene position: 908082-908993 (Clockwise)

Preceding gene: 21673789

Following gene: 21673792

Centisome position: 42.14

GC content: 55.48

Gene sequence:

>912_bases
ATGGCAAAACATCTGAAGCCTTATCCTGCGGAGAAAAAAGGCAAGTACTTGCAGCTTTCAACCATCGATGAACTCAAGGA
CATGGCCCGGCAGGTGCGCAGGGATGTGATCCGCATGCTGGCTAAAGCCAATTCGGGCCATACCGGCGGTTCGCTTGGCA
TGGCCGATATTTTTACGGCACTGTATTTCAAAATTCTGAAGCATCATCCGCATCAGTTCAAGGGCGAAGCCGATCAGGAT
ATGCTGTTTCTCTCGAACGGCCATATTGCTCCGGTCTGGTACAGCGTACTGGCCCGTTCGGGGTACTTTTCTCTCAATGA
GCTCAACTACCTGCGCGAAATCAACTCGTACCTGCAGGGGCACCCGACCTGCGAGTCAGGGCTGCCGGGCATCAATATCG
CATCCGGTTCGCTGGGTCAGGGTTTGTCGGCGGCTGTCGGTGCGGCGCTCGGCCTGCGCATGGATGGCAAAAAGGGTGAG
GTGTTTTGCCTGATGGGTGACGGTGAGTGCCAGGAAGGGCAGATCTGGGAGGCTGCCATGAGCGCCGCCCATTATCAGCT
CGGCAACCTGATCGGCATCGTCGATTACAACAACCAGCAGATTGACGGCGAGGTTTCGGAGGTGATGGACATCGAGCCGT
TCGCCGACAAGTGGCGCGCCTTCGGCTGGGATGTGCTCTCCTGCGACGGTAACGACATCGAGCATTTCATCGATACGCTT
GAGTATCTTCGCAAGGATACAGGCCGCACCAAACCGGTGGTGGTTTTGGCTAAAACGGTTATGGGCAAGGGGGTGCCGTT
CTTTGAAGGTACGATGCCCGACAAGTCCAACTGGCATGGCAAACCGCCATCCAAAGAGGACGAGGCAAAAGCGCTGGAGA
TTCTCGGCGTAACTATTTTCGGTGACTTTTAA

Upstream 100 bases:

>100_bases
GGCGTCCGCTTTTAACTTTGAGGTTTTCTGACGGGCGGTTTCCGGCGTTCTTCTGACACCATTTTTTATTTTCAGCCATC
ATTCATCCATCGCTTCCATC

Downstream 100 bases:

>100_bases
GCTGTTTCGATAGGTTTTGCAGATTCATGCGGGCAGATACCGGGGGCGAAAGATCAGGCATCTGCCTTCGCGCGACATCC
GGCCCTGCACCAGCAGGGTC

Product: transketolase, N-terminal subunit

Products: NA

Alternate protein names: TK [H]

Number of amino acids: Translated: 303; Mature: 302

Protein sequence:

>303_residues
MAKHLKPYPAEKKGKYLQLSTIDELKDMARQVRRDVIRMLAKANSGHTGGSLGMADIFTALYFKILKHHPHQFKGEADQD
MLFLSNGHIAPVWYSVLARSGYFSLNELNYLREINSYLQGHPTCESGLPGINIASGSLGQGLSAAVGAALGLRMDGKKGE
VFCLMGDGECQEGQIWEAAMSAAHYQLGNLIGIVDYNNQQIDGEVSEVMDIEPFADKWRAFGWDVLSCDGNDIEHFIDTL
EYLRKDTGRTKPVVVLAKTVMGKGVPFFEGTMPDKSNWHGKPPSKEDEAKALEILGVTIFGDF

Sequences:

>Translated_303_residues
MAKHLKPYPAEKKGKYLQLSTIDELKDMARQVRRDVIRMLAKANSGHTGGSLGMADIFTALYFKILKHHPHQFKGEADQD
MLFLSNGHIAPVWYSVLARSGYFSLNELNYLREINSYLQGHPTCESGLPGINIASGSLGQGLSAAVGAALGLRMDGKKGE
VFCLMGDGECQEGQIWEAAMSAAHYQLGNLIGIVDYNNQQIDGEVSEVMDIEPFADKWRAFGWDVLSCDGNDIEHFIDTL
EYLRKDTGRTKPVVVLAKTVMGKGVPFFEGTMPDKSNWHGKPPSKEDEAKALEILGVTIFGDF
>Mature_302_residues
AKHLKPYPAEKKGKYLQLSTIDELKDMARQVRRDVIRMLAKANSGHTGGSLGMADIFTALYFKILKHHPHQFKGEADQDM
LFLSNGHIAPVWYSVLARSGYFSLNELNYLREINSYLQGHPTCESGLPGINIASGSLGQGLSAAVGAALGLRMDGKKGEV
FCLMGDGECQEGQIWEAAMSAAHYQLGNLIGIVDYNNQQIDGEVSEVMDIEPFADKWRAFGWDVLSCDGNDIEHFIDTLE
YLRKDTGRTKPVVVLAKTVMGKGVPFFEGTMPDKSNWHGKPPSKEDEAKALEILGVTIFGDF

Specific function: Unknown

COG id: COG3959

COG function: function code G; Transketolase, N-terminal subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the transketolase family [H]

Homologues:

Organism=Homo sapiens, GI133778974, Length=275, Percent_Identity=35.6363636363636, Blast_Score=168, Evalue=5e-42,
Organism=Homo sapiens, GI205277463, Length=267, Percent_Identity=35.5805243445693, Blast_Score=159, Evalue=2e-39,
Organism=Homo sapiens, GI4507521, Length=267, Percent_Identity=35.5805243445693, Blast_Score=159, Evalue=2e-39,
Organism=Homo sapiens, GI225637459, Length=267, Percent_Identity=29.9625468164794, Blast_Score=114, Evalue=8e-26,
Organism=Homo sapiens, GI225637463, Length=160, Percent_Identity=37.5, Blast_Score=106, Evalue=2e-23,
Organism=Homo sapiens, GI225637461, Length=160, Percent_Identity=37.5, Blast_Score=106, Evalue=3e-23,
Organism=Escherichia coli, GI1788808, Length=283, Percent_Identity=34.982332155477, Blast_Score=135, Evalue=4e-33,
Organism=Escherichia coli, GI48994911, Length=291, Percent_Identity=34.7079037800687, Blast_Score=123, Evalue=1e-29,
Organism=Caenorhabditis elegans, GI17539652, Length=261, Percent_Identity=37.1647509578544, Blast_Score=172, Evalue=2e-43,
Organism=Saccharomyces cerevisiae, GI6319593, Length=260, Percent_Identity=35, Blast_Score=126, Evalue=4e-30,
Organism=Saccharomyces cerevisiae, GI6325331, Length=260, Percent_Identity=33.8461538461538, Blast_Score=121, Evalue=1e-28,
Organism=Drosophila melanogaster, GI45551847, Length=269, Percent_Identity=34.5724907063197, Blast_Score=159, Evalue=2e-39,
Organism=Drosophila melanogaster, GI45550715, Length=269, Percent_Identity=34.5724907063197, Blast_Score=159, Evalue=2e-39,
Organism=Drosophila melanogaster, GI24666278, Length=277, Percent_Identity=33.5740072202166, Blast_Score=148, Evalue=5e-36,
Organism=Drosophila melanogaster, GI24645119, Length=228, Percent_Identity=35.5263157894737, Blast_Score=136, Evalue=1e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005474 [H]

Pfam domain/function: PF00456 Transketolase_N [H]

EC number: =2.2.1.1 [H]

Molecular weight: Translated: 33432; Mature: 33300

Theoretical pI: Translated: 6.00; Mature: 6.00

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKHLKPYPAEKKGKYLQLSTIDELKDMARQVRRDVIRMLAKANSGHTGGSLGMADIFTA
CCCCCCCCCCCCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHH
LYFKILKHHPHQFKGEADQDMLFLSNGHIAPVWYSVLARSGYFSLNELNYLREINSYLQG
HHHHHHHCCCCCCCCCCCCCEEEEECCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCC
HPTCESGLPGINIASGSLGQGLSAAVGAALGLRMDGKKGEVFCLMGDGECQEGQIWEAAM
CCCHHCCCCCCEECCCCCCCCHHHHHHHHHCEEECCCCCCEEEEECCCCCCCCHHHHHHH
SAAHYQLGNLIGIVDYNNQQIDGEVSEVMDIEPFADKWRAFGWDVLSCDGNDIEHFIDTL
HHHHHHHCCEEEEEECCCCCCCCHHHHHHCCCHHHHHHHHCCCEEEECCCCCHHHHHHHH
EYLRKDTGRTKPVVVLAKTVMGKGVPFFEGTMPDKSNWHGKPPSKEDEAKALEILGVTIF
HHHHHHCCCCCCEEEEEHHHHCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHEEEEEE
GDF
ECC
>Mature Secondary Structure 
AKHLKPYPAEKKGKYLQLSTIDELKDMARQVRRDVIRMLAKANSGHTGGSLGMADIFTA
CCCCCCCCCCCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHH
LYFKILKHHPHQFKGEADQDMLFLSNGHIAPVWYSVLARSGYFSLNELNYLREINSYLQG
HHHHHHHCCCCCCCCCCCCCEEEEECCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCC
HPTCESGLPGINIASGSLGQGLSAAVGAALGLRMDGKKGEVFCLMGDGECQEGQIWEAAM
CCCHHCCCCCCEECCCCCCCCHHHHHHHHHCEEECCCCCCEEEEECCCCCCCCHHHHHHH
SAAHYQLGNLIGIVDYNNQQIDGEVSEVMDIEPFADKWRAFGWDVLSCDGNDIEHFIDTL
HHHHHHHCCEEEEEECCCCCCCCHHHHHHCCCHHHHHHHHCCCEEEECCCCCHHHHHHHH
EYLRKDTGRTKPVVVLAKTVMGKGVPFFEGTMPDKSNWHGKPPSKEDEAKALEILGVTIF
HHHHHHCCCCCCEEEEEHHHHCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHEEEEEE
GDF
ECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]