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The map label for this gene is bioC [H]

Identifier: 21672890

GI number: 21672890

Start: 47436

End: 48218

Strand: Reverse

Name: bioC [H]

Synonym: CT0049

Alternate gene names: 21672890

Gene position: 48218-47436 (Counterclockwise)

Preceding gene: 21672891

Following gene: 21672889

Centisome position: 2.24

GC content: 63.73

Gene sequence:

>783_bases
ATGAACGGCGTGATCGACAAGCAGCTCGTGCGCCGCCGCTTCCGGCGGGCGCTGCCAACCTACGCAGGACACGCCGAGGT
GCAGCGGCGCATGGCCGTGCGGCTGGTCGCGCTGATCGAAAACGCCGGAGCCTCAACGCATCTCGGGCGCGTCTTCGAGT
TCGGCAGCGGCTCGGCCATGCTCACCTCGATACTCTTCGAGCGCTATTCTGCGAACGAATTCTTCGCCAACGACCTCGTC
GCCGAAAGCCGCGCCTTTGTCGAAAAAGCGGTGACGGGACGGAATGTCGAACGGCTGACGTTCCTGCCCGGCGACGTCGA
GCGGCTCGATCCGTTGCCCGGAAATCTCGACCTCGCCGTCTCGAACGCCACGGTGCAGTGGCTGCACGACCCGGCGCGAT
TTTTCGATCGGCTGGCAACATCGGTGAAACCCGGCGGCATCGTGGCCTTCAGCACCTTCGGTGCGGAAAACATGCACGAA
ATCGCCGCGCTCGGCGAGGCGGCGCTGCCCTACCGGAGCCTCGACAAAATCGCCGCGCTCAGCGGAGAGCTGTTCGAGCT
GGTCGCAATCGAAGACGACATCGTCCGGCAGGAGTTCGACACGCCGGAGGCGGTGCTTCGCCACATCCGCAAAACCGGCG
TGAACGGCGTAGCCCGCCGCGCCTGGACGCGCTCGCAGTACCTCGATTTTCTGCAACGCTACCGGTCAGCCTACCCGTCA
GGCGAAGGCGTTACGCTCACCTGGCATCCGGTATATTGCTGTTTCAGAAAGAAAAAGTCATGA

Upstream 100 bases:

>100_bases
AGCGCCGCGCGTGGAGCGAGGCGGGGGTTCGCGTCGCCGAAATCGCCGCAATGCCCCACTTCCCGTTCACCCACATCGCC
GGCTGGGGGGAGCTTTTCAC

Downstream 100 bases:

>100_bases
AAGGACAGGTACTCGCCATCTCCGGCATCGACACCGGCATCGGCAAAACCGTCGTCACCGGCCTGCTCGCCCGGTGCTTC
GCTGAAACGGGCTGGCGGAC

Product: biotin synthesis protein, putative

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 260; Mature: 260

Protein sequence:

>260_residues
MNGVIDKQLVRRRFRRALPTYAGHAEVQRRMAVRLVALIENAGASTHLGRVFEFGSGSAMLTSILFERYSANEFFANDLV
AESRAFVEKAVTGRNVERLTFLPGDVERLDPLPGNLDLAVSNATVQWLHDPARFFDRLATSVKPGGIVAFSTFGAENMHE
IAALGEAALPYRSLDKIAALSGELFELVAIEDDIVRQEFDTPEAVLRHIRKTGVNGVARRAWTRSQYLDFLQRYRSAYPS
GEGVTLTWHPVYCCFRKKKS

Sequences:

>Translated_260_residues
MNGVIDKQLVRRRFRRALPTYAGHAEVQRRMAVRLVALIENAGASTHLGRVFEFGSGSAMLTSILFERYSANEFFANDLV
AESRAFVEKAVTGRNVERLTFLPGDVERLDPLPGNLDLAVSNATVQWLHDPARFFDRLATSVKPGGIVAFSTFGAENMHE
IAALGEAALPYRSLDKIAALSGELFELVAIEDDIVRQEFDTPEAVLRHIRKTGVNGVARRAWTRSQYLDFLQRYRSAYPS
GEGVTLTWHPVYCCFRKKKS
>Mature_260_residues
MNGVIDKQLVRRRFRRALPTYAGHAEVQRRMAVRLVALIENAGASTHLGRVFEFGSGSAMLTSILFERYSANEFFANDLV
AESRAFVEKAVTGRNVERLTFLPGDVERLDPLPGNLDLAVSNATVQWLHDPARFFDRLATSVKPGGIVAFSTFGAENMHE
IAALGEAALPYRSLDKIAALSGELFELVAIEDDIVRQEFDTPEAVLRHIRKTGVNGVARRAWTRSQYLDFLQRYRSAYPS
GEGVTLTWHPVYCCFRKKKS

Specific function: BioC is involved in an early, but chemically unexplored, step in the conversion of pimelic acid to biotin [H]

COG id: COG0500

COG function: function code QR; SAM-dependent methyltransferases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011814
- InterPro:   IPR013216 [H]

Pfam domain/function: PF08241 Methyltransf_11 [H]

EC number: NA

Molecular weight: Translated: 29108; Mature: 29108

Theoretical pI: Translated: 9.37; Mature: 9.37

Prosite motif: PS00639 THIOL_PROTEASE_HIS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNGVIDKQLVRRRFRRALPTYAGHAEVQRRMAVRLVALIENAGASTHLGRVFEFGSGSAM
CCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCCCCHHH
LTSILFERYSANEFFANDLVAESRAFVEKAVTGRNVERLTFLPGDVERLDPLPGNLDLAV
HHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCHHHCCCCCCCEEEEE
SNATVQWLHDPARFFDRLATSVKPGGIVAFSTFGAENMHEIAALGEAALPYRSLDKIAAL
ECCCHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCHHHHHHHHHHHHCCHHHHHHHHHH
SGELFELVAIEDDIVRQEFDTPEAVLRHIRKTGVNGVARRAWTRSQYLDFLQRYRSAYPS
CCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCC
GEGVTLTWHPVYCCFRKKKS
CCCEEEEEHHHHHHHHCCCC
>Mature Secondary Structure
MNGVIDKQLVRRRFRRALPTYAGHAEVQRRMAVRLVALIENAGASTHLGRVFEFGSGSAM
CCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCCCCHHH
LTSILFERYSANEFFANDLVAESRAFVEKAVTGRNVERLTFLPGDVERLDPLPGNLDLAV
HHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCHHHCCCCCCCEEEEE
SNATVQWLHDPARFFDRLATSVKPGGIVAFSTFGAENMHEIAALGEAALPYRSLDKIAAL
ECCCHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCHHHHHHHHHHHHCCHHHHHHHHHH
SGELFELVAIEDDIVRQEFDTPEAVLRHIRKTGVNGVARRAWTRSQYLDFLQRYRSAYPS
CCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCC
GEGVTLTWHPVYCCFRKKKS
CCCEEEEEHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]