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The map label for this gene is ftsA [H]

Identifier: 21672872

GI number: 21672872

Start: 26772

End: 28115

Strand: Reverse

Name: ftsA [H]

Synonym: CT0031

Alternate gene names: 21672872

Gene position: 28115-26772 (Counterclockwise)

Preceding gene: 21672873

Following gene: 21672871

Centisome position: 1.3

GC content: 58.33

Gene sequence:

>1344_bases
TTGAACTCAAAACTTCTCATGCCGAAGAGCAATATTGTAGTCGGTCTCGATATAGGTACAACCAAGGTCTGCGTCGTCGT
CGCCGAAAAGGACGACGTCGGCAAGCTCAACGTCCTCGGCAAGGGGCGCGCCAACTCTGAGGGGTTGCAACGGGCGACGG
TGGTCAACATCAACAAGACGGTTGACGCCATCAGGAAGGCGGTGGCCGATGCTGAACGCGAGTCGTCGATCAAAATCAAG
GGAGTCAACGTCGGCATCTCCGGCGCGCACGTCCACTGCATCTACAGCAACTCCGAAATCAGCGTCAACCAGTCGGGCAT
CGTCAACGAGTCCGATGTGCGGCGCTTCCTCGAAAAGGCCAAAACCAACATCCGCTATCTCGACATCGACCACGAGATCA
TTCACGTCATTCCACAGGAGTTCATCGTCGATGACCAGGATGGCGTGCTCGATCCGATCGGCATGGCCGGAACGATCATG
CGCGGCAGCGCCTACATCGTCGTTGGACTTCGGACCAAGATCCGCAACATCAAGCAGTGCATCGAAAAGGCAGGCCTCGA
AGTCAGCGCCATGACCTTTGAGCCGGTGGCCTCCGGTCTCGCCGTGATGAAGGAGAGCGAGAGGCGGAGCGGCGTGGTGG
TGATCGACATCGGCGGCGGCACCACCGAGGTGGCCATCTACATCGACGGCGCGATCCGTTATTCCGAGGTGATCAAGGTT
GCGGCCAACGATGTGACTCACGATGTGGCCTATGGCATCAAGGCACTCAACGACGTGGCTGAAGAGATCAAGATCCAGCA
CGGATGCGCCTATGCAAAGGTGCTCGACAAGGAGGAGGAGATCCTGATCGAGAGCATCGAGGGACGGCCGAGCAAGTCGT
TCCCGAAAAGCTCCCTGACGGTGATCATCGAAGCCCGCATGATGGAGATTTTCGAACTGGTGCGAGACATCATCAAGCGC
TCGGGCTACTACGACTACCTGAACGCCGGAGTCATCATCACCGGCGGCGGCGCGCTCTTGCCCGGCACCGGCGAGCTGGC
CAGGGACATTCTCGGTCTCGACGTGCGCACGGGCTATCCGGAAGGGGTTTCGGGCGGCATCAAGGATGCGATCAACAACC
CGATGTACGCAACGGTGATGGGTCTGGTAGCTCACTCGCTCCAGAACAATCTGTACCAGGATTACGGAGAGGTTGCCCCG
GCACCGTCCGGGCAGACTCAGGAGCCGGTTACGTCTTCTCCTGAACCCTCGCAGGCTCAACAGAGTCCCGAGCAGAATCC
CGATACCCCGCCAACCGGAAAGAAGTTTGTTGACCGTCTGAAAAAGTTTTGGGATCAGTTGTAG

Upstream 100 bases:

>100_bases
GAGTGTTCGCCACTTCGCCCGTAAACGAAGAAGCCTCCGTAGATTCTACAGCGGCGCCGGTTGCCCCGCCTGCGGGCGGC
CAACTTCCCGATGAACACCA

Downstream 100 bases:

>100_bases
CAGAGATAGTTACCTGTAACGACAGGAAAAACAAGGAATAGAGAGTATGGCATTCGAACTCGATCCAGGCCTGTTCGACA
GCGATCAGGACAGCGGAGTC

Product: cell division protein FtsA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 447; Mature: 447

Protein sequence:

>447_residues
MNSKLLMPKSNIVVGLDIGTTKVCVVVAEKDDVGKLNVLGKGRANSEGLQRATVVNINKTVDAIRKAVADAERESSIKIK
GVNVGISGAHVHCIYSNSEISVNQSGIVNESDVRRFLEKAKTNIRYLDIDHEIIHVIPQEFIVDDQDGVLDPIGMAGTIM
RGSAYIVVGLRTKIRNIKQCIEKAGLEVSAMTFEPVASGLAVMKESERRSGVVVIDIGGGTTEVAIYIDGAIRYSEVIKV
AANDVTHDVAYGIKALNDVAEEIKIQHGCAYAKVLDKEEEILIESIEGRPSKSFPKSSLTVIIEARMMEIFELVRDIIKR
SGYYDYLNAGVIITGGGALLPGTGELARDILGLDVRTGYPEGVSGGIKDAINNPMYATVMGLVAHSLQNNLYQDYGEVAP
APSGQTQEPVTSSPEPSQAQQSPEQNPDTPPTGKKFVDRLKKFWDQL

Sequences:

>Translated_447_residues
MNSKLLMPKSNIVVGLDIGTTKVCVVVAEKDDVGKLNVLGKGRANSEGLQRATVVNINKTVDAIRKAVADAERESSIKIK
GVNVGISGAHVHCIYSNSEISVNQSGIVNESDVRRFLEKAKTNIRYLDIDHEIIHVIPQEFIVDDQDGVLDPIGMAGTIM
RGSAYIVVGLRTKIRNIKQCIEKAGLEVSAMTFEPVASGLAVMKESERRSGVVVIDIGGGTTEVAIYIDGAIRYSEVIKV
AANDVTHDVAYGIKALNDVAEEIKIQHGCAYAKVLDKEEEILIESIEGRPSKSFPKSSLTVIIEARMMEIFELVRDIIKR
SGYYDYLNAGVIITGGGALLPGTGELARDILGLDVRTGYPEGVSGGIKDAINNPMYATVMGLVAHSLQNNLYQDYGEVAP
APSGQTQEPVTSSPEPSQAQQSPEQNPDTPPTGKKFVDRLKKFWDQL
>Mature_447_residues
MNSKLLMPKSNIVVGLDIGTTKVCVVVAEKDDVGKLNVLGKGRANSEGLQRATVVNINKTVDAIRKAVADAERESSIKIK
GVNVGISGAHVHCIYSNSEISVNQSGIVNESDVRRFLEKAKTNIRYLDIDHEIIHVIPQEFIVDDQDGVLDPIGMAGTIM
RGSAYIVVGLRTKIRNIKQCIEKAGLEVSAMTFEPVASGLAVMKESERRSGVVVIDIGGGTTEVAIYIDGAIRYSEVIKV
AANDVTHDVAYGIKALNDVAEEIKIQHGCAYAKVLDKEEEILIESIEGRPSKSFPKSSLTVIIEARMMEIFELVRDIIKR
SGYYDYLNAGVIITGGGALLPGTGELARDILGLDVRTGYPEGVSGGIKDAINNPMYATVMGLVAHSLQNNLYQDYGEVAP
APSGQTQEPVTSSPEPSQAQQSPEQNPDTPPTGKKFVDRLKKFWDQL

Specific function: This protein may be involved in anomalous filament growth. May be a component of the septum [H]

COG id: COG0849

COG function: function code D; Actin-like ATPase involved in cell division

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ftsA/mreB family [H]

Homologues:

Organism=Escherichia coli, GI1786282, Length=387, Percent_Identity=33.3333333333333, Blast_Score=241, Evalue=5e-65,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020823
- InterPro:   IPR003494 [H]

Pfam domain/function: PF02491 FtsA [H]

EC number: NA

Molecular weight: Translated: 48334; Mature: 48334

Theoretical pI: Translated: 5.24; Mature: 5.24

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNSKLLMPKSNIVVGLDIGTTKVCVVVAEKDDVGKLNVLGKGRANSEGLQRATVVNINKT
CCCCEECCCCCEEEEEECCCCEEEEEEECCCCCCEEEEEECCCCCCCCCCEEEEEECHHH
VDAIRKAVADAERESSIKIKGVNVGISGAHVHCIYSNSEISVNQSGIVNESDVRRFLEKA
HHHHHHHHHHCCCCCCEEEEEEEEEECCEEEEEEEECCEEEECCCCCCCHHHHHHHHHHH
KTNIRYLDIDHEIIHVIPQEFIVDDQDGVLDPIGMAGTIMRGSAYIVVGLRTKIRNIKQC
HCCEEEEECCHHHHHHCCHHHEECCCCCCCCCCCCCCEEECCCEEEEEEHHHHHHHHHHH
IEKAGLEVSAMTFEPVASGLAVMKESERRSGVVVIDIGGGTTEVAIYIDGAIRYSEVIKV
HHHCCCEEEEEEHHHHHHHHHHHHHHHCCCCEEEEEECCCCEEEEEEECCCHHHHHHHHH
AANDVTHDVAYGIKALNDVAEEIKIQHGCAYAKVLDKEEEILIESIEGRPSKSFPKSSLT
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCCHHHHHHHCCCCCCCCCCCCCEE
VIIEARMMEIFELVRDIIKRSGYYDYLNAGVIITGGGALLPGTGELARDILGLDVRTGYP
EEEHHHHHHHHHHHHHHHHHCCCCEEECCCEEEECCCEECCCCHHHHHHHHCCCCCCCCC
EGVSGGIKDAINNPMYATVMGLVAHSLQNNLYQDYGEVAPAPSGQTQEPVTSSPEPSQAQ
CCCCCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHH
QSPEQNPDTPPTGKKFVDRLKKFWDQL
CCCCCCCCCCCCHHHHHHHHHHHHHCC
>Mature Secondary Structure
MNSKLLMPKSNIVVGLDIGTTKVCVVVAEKDDVGKLNVLGKGRANSEGLQRATVVNINKT
CCCCEECCCCCEEEEEECCCCEEEEEEECCCCCCEEEEEECCCCCCCCCCEEEEEECHHH
VDAIRKAVADAERESSIKIKGVNVGISGAHVHCIYSNSEISVNQSGIVNESDVRRFLEKA
HHHHHHHHHHCCCCCCEEEEEEEEEECCEEEEEEEECCEEEECCCCCCCHHHHHHHHHHH
KTNIRYLDIDHEIIHVIPQEFIVDDQDGVLDPIGMAGTIMRGSAYIVVGLRTKIRNIKQC
HCCEEEEECCHHHHHHCCHHHEECCCCCCCCCCCCCCEEECCCEEEEEEHHHHHHHHHHH
IEKAGLEVSAMTFEPVASGLAVMKESERRSGVVVIDIGGGTTEVAIYIDGAIRYSEVIKV
HHHCCCEEEEEEHHHHHHHHHHHHHHHCCCCEEEEEECCCCEEEEEEECCCHHHHHHHHH
AANDVTHDVAYGIKALNDVAEEIKIQHGCAYAKVLDKEEEILIESIEGRPSKSFPKSSLT
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCCHHHHHHHCCCCCCCCCCCCCEE
VIIEARMMEIFELVRDIIKRSGYYDYLNAGVIITGGGALLPGTGELARDILGLDVRTGYP
EEEHHHHHHHHHHHHHHHHHCCCCEEECCCEEEECCCEECCCCHHHHHHHHCCCCCCCCC
EGVSGGIKDAINNPMYATVMGLVAHSLQNNLYQDYGEVAPAPSGQTQEPVTSSPEPSQAQ
CCCCCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHH
QSPEQNPDTPPTGKKFVDRLKKFWDQL
CCCCCCCCCCCCHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10984043; 8581173 [H]