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The map label for this gene is cat2 [H]

Identifier: 21672870

GI number: 21672870

Start: 23975

End: 25270

Strand: Reverse

Name: cat2 [H]

Synonym: CT0029

Alternate gene names: 21672870

Gene position: 25270-23975 (Counterclockwise)

Preceding gene: 21672871

Following gene: 21672868

Centisome position: 1.17

GC content: 62.11

Gene sequence:

>1296_bases
ATGAGTTACCGGACGATATCCGCAGAAGAGGCCGTCATGGCCATCAAGTCGGGAGACAGGGTTTTTCTGCACACCGCGGC
GGCAACGCCCCTCAGGCTGATCGAGGCGATGGTCAGCCGCGCCAGCCATCTGCGTGACGTCGAGATCGTCAGCCTGCACA
CCGAGGGCGACGCACCGTACGTCAGACCTGAATTTCAGGAGAGCTTCAGGCTCAACGCCTTCTTTGTCGGAAGGAACGTC
CGTTCGGCGGTGCAGTGCGGCTACGCCGATGCTATCCCGATTTTTCTGAGCGACGTGCCCGCGATGTTCTACGACGGAGT
CATGCCGCTCGACGTGGCACTGGTGCACGTTTCGCCGCCCGACCGTCACGGCTACTGCTCGCTCGGGGTGTCGGTTGATG
CGACCCGCGCCGCCGTGCATACCGCCCGGCACGTCATCGCCCAGGTGAACCCGAACATGCCCCGCACCCACGGCGAAGGG
CTGCTGCATGTCAGCAAGATTCATTCGCTGGTCGAGGTGGACGATCCTCTGCCGGAGACGCCGCGCCACGAGCTGACCGA
CGTCGAGCGCCAGATCGGCCAGCATATCGCCTCCATCGTCGAGGACGGCGCGACGCTACAGATGGGCATTGGCGCGATTC
CCGACGCGACGCTTGCCGCGCTGACGAACCACAAGGACCTTGGCATCCACTCGGAGATGTTTTCCGACGGCGTGGTCGAT
CTGGTTGAAAAGGGGGTGGTGAACGGACGCTGCAAGAAAACACACAACGAGATCATTGTGGCGAGCTTCCTTGTTGGCAC
CCGGAAGCTCTACGATTTCGTGGACGACAATCCGCTGGTCGAGATGTTCGGCTCGGACTACGTGAACGACACGAAGGAGA
TTCGCAAAAACCCGAAGGTGACAGCCATCAACAGCGCCATCGAAATCGACATGACCGGCCAGGTGTGCGCTGACTCGATC
GGCACCCGCCACTTTTCAGGTGTCGGCGGCCAGATGGACTTCATCCGCGGCGCGGCGCTTTCCCCCGGCGGCAAGCCGAT
CATCGCCCTTCCCGCCACAACGCGCAAGGGCGAGTCACGCATCGTGACGCAGCTCAAGCCCGGTGCAGGTGTCGTGACCA
CAAGGGCACACGTGCAGTACGTCGTCACCGAATACGGCATTGTCAACCTGCACGGCAAGAACCTCCGCCAGCGAGCTGAA
GCGCTCGCCACCATCGCCCACCCCGACTTCCGCGAAGAGATCCTCCGCCAGGCACACGAGCTGTATGGGCGAAAAAGCAA
TTGCCTGATCGATTGA

Upstream 100 bases:

>100_bases
TTTACCACTATCCATGAGCATCGCCATTCTTTGGGGCTAATCGCCTGAATTACGAGGCAGAGGCGGAGCTGTAACCAGTT
CAAAAAGGAGTCAAAGTATC

Downstream 100 bases:

>100_bases
TGAATTGGGAAAAGTGCCGATGAACGCGTAAGGGCAGGTCTCGAACCTGTCGTCTTTGAAGAGTGCAGTCAAATAAGCCC
TATACGAGAAAAGGCTGCCC

Product: 4-hydroxybutyrate coenzyme A transferase

Products: propionate; succinyl-CoA [C]

Alternate protein names: NA

Number of amino acids: Translated: 431; Mature: 430

Protein sequence:

>431_residues
MSYRTISAEEAVMAIKSGDRVFLHTAAATPLRLIEAMVSRASHLRDVEIVSLHTEGDAPYVRPEFQESFRLNAFFVGRNV
RSAVQCGYADAIPIFLSDVPAMFYDGVMPLDVALVHVSPPDRHGYCSLGVSVDATRAAVHTARHVIAQVNPNMPRTHGEG
LLHVSKIHSLVEVDDPLPETPRHELTDVERQIGQHIASIVEDGATLQMGIGAIPDATLAALTNHKDLGIHSEMFSDGVVD
LVEKGVVNGRCKKTHNEIIVASFLVGTRKLYDFVDDNPLVEMFGSDYVNDTKEIRKNPKVTAINSAIEIDMTGQVCADSI
GTRHFSGVGGQMDFIRGAALSPGGKPIIALPATTRKGESRIVTQLKPGAGVVTTRAHVQYVVTEYGIVNLHGKNLRQRAE
ALATIAHPDFREEILRQAHELYGRKSNCLID

Sequences:

>Translated_431_residues
MSYRTISAEEAVMAIKSGDRVFLHTAAATPLRLIEAMVSRASHLRDVEIVSLHTEGDAPYVRPEFQESFRLNAFFVGRNV
RSAVQCGYADAIPIFLSDVPAMFYDGVMPLDVALVHVSPPDRHGYCSLGVSVDATRAAVHTARHVIAQVNPNMPRTHGEG
LLHVSKIHSLVEVDDPLPETPRHELTDVERQIGQHIASIVEDGATLQMGIGAIPDATLAALTNHKDLGIHSEMFSDGVVD
LVEKGVVNGRCKKTHNEIIVASFLVGTRKLYDFVDDNPLVEMFGSDYVNDTKEIRKNPKVTAINSAIEIDMTGQVCADSI
GTRHFSGVGGQMDFIRGAALSPGGKPIIALPATTRKGESRIVTQLKPGAGVVTTRAHVQYVVTEYGIVNLHGKNLRQRAE
ALATIAHPDFREEILRQAHELYGRKSNCLID
>Mature_430_residues
SYRTISAEEAVMAIKSGDRVFLHTAAATPLRLIEAMVSRASHLRDVEIVSLHTEGDAPYVRPEFQESFRLNAFFVGRNVR
SAVQCGYADAIPIFLSDVPAMFYDGVMPLDVALVHVSPPDRHGYCSLGVSVDATRAAVHTARHVIAQVNPNMPRTHGEGL
LHVSKIHSLVEVDDPLPETPRHELTDVERQIGQHIASIVEDGATLQMGIGAIPDATLAALTNHKDLGIHSEMFSDGVVDL
VEKGVVNGRCKKTHNEIIVASFLVGTRKLYDFVDDNPLVEMFGSDYVNDTKEIRKNPKVTAINSAIEIDMTGQVCADSIG
TRHFSGVGGQMDFIRGAALSPGGKPIIALPATTRKGESRIVTQLKPGAGVVTTRAHVQYVVTEYGIVNLHGKNLRQRAEA
LATIAHPDFREEILRQAHELYGRKSNCLID

Specific function: Unknown

COG id: COG0427

COG function: function code C; Acetyl-CoA hydrolase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acetyl-CoA hydrolase/transferase family [H]

Homologues:

Organism=Escherichia coli, GI1789287, Length=483, Percent_Identity=24.4306418219462, Blast_Score=74, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI32563853, Length=426, Percent_Identity=51.4084507042254, Blast_Score=426, Evalue=1e-120,
Organism=Caenorhabditis elegans, GI17538151, Length=429, Percent_Identity=43.8228438228438, Blast_Score=369, Evalue=1e-102,
Organism=Saccharomyces cerevisiae, GI6319456, Length=280, Percent_Identity=28.9285714285714, Blast_Score=76, Evalue=8e-15,
Organism=Drosophila melanogaster, GI21358615, Length=420, Percent_Identity=55.7142857142857, Blast_Score=477, Evalue=1e-135,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003702 [H]

Pfam domain/function: PF02550 AcetylCoA_hydro [H]

EC number: NA

Molecular weight: Translated: 46984; Mature: 46853

Theoretical pI: Translated: 6.59; Mature: 6.59

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSYRTISAEEAVMAIKSGDRVFLHTAAATPLRLIEAMVSRASHLRDVEIVSLHTEGDAPY
CCCCCCCHHHHEEEEECCCEEEEEECCCCHHHHHHHHHHHHHHCCCEEEEEEEECCCCCC
VRPEFQESFRLNAFFVGRNVRSAVQCGYADAIPIFLSDVPAMFYDGVMPLDVALVHVSPP
CCCCHHHCCEEEEEEECCCHHHHHHCCCCCCHHHHHHCCCHHHHCCCCEEEEEEEEECCC
DRHGYCSLGVSVDATRAAVHTARHVIAQVNPNMPRTHGEGLLHVSKIHSLVEVDDPLPET
CCCCEEEECCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEHHHHHHHHHCCCCCCCC
PRHELTDVERQIGQHIASIVEDGATLQMGIGAIPDATLAALTNHKDLGIHSEMFSDGVVD
CCHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCHHHHHHCCCCCCCCHHHHHCCHHHH
LVEKGVVNGRCKKTHNEIIVASFLVGTRKLYDFVDDNPLVEMFGSDYVNDTKEIRKNPKV
HHHCCCCCCCCHHCCCCEEEEHHHHHHHHHHHHHCCCHHHHHHCCCCCCCHHHHHCCCCE
TAINSAIEIDMTGQVCADSIGTRHFSGVGGQMDFIRGAALSPGGKPIIALPATTRKGESR
EEECCEEEEECCCHHHHHHHCCCCCCCCCCCHHHHCCCCCCCCCCEEEEECCCCCCCCCE
IVTQLKPGAGVVTTRAHVQYVVTEYGIVNLHGKNLRQRAEALATIAHPDFREEILRQAHE
EEEEECCCCCEEEEHHHHEEEEECCCEEEECCHHHHHHHHHHHHHCCCCHHHHHHHHHHH
LYGRKSNCLID
HHCCCCCCCCC
>Mature Secondary Structure 
SYRTISAEEAVMAIKSGDRVFLHTAAATPLRLIEAMVSRASHLRDVEIVSLHTEGDAPY
CCCCCCHHHHEEEEECCCEEEEEECCCCHHHHHHHHHHHHHHCCCEEEEEEEECCCCCC
VRPEFQESFRLNAFFVGRNVRSAVQCGYADAIPIFLSDVPAMFYDGVMPLDVALVHVSPP
CCCCHHHCCEEEEEEECCCHHHHHHCCCCCCHHHHHHCCCHHHHCCCCEEEEEEEEECCC
DRHGYCSLGVSVDATRAAVHTARHVIAQVNPNMPRTHGEGLLHVSKIHSLVEVDDPLPET
CCCCEEEECCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEHHHHHHHHHCCCCCCCC
PRHELTDVERQIGQHIASIVEDGATLQMGIGAIPDATLAALTNHKDLGIHSEMFSDGVVD
CCHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCHHHHHHCCCCCCCCHHHHHCCHHHH
LVEKGVVNGRCKKTHNEIIVASFLVGTRKLYDFVDDNPLVEMFGSDYVNDTKEIRKNPKV
HHHCCCCCCCCHHCCCCEEEEHHHHHHHHHHHHHCCCHHHHHHCCCCCCCHHHHHCCCCE
TAINSAIEIDMTGQVCADSIGTRHFSGVGGQMDFIRGAALSPGGKPIIALPATTRKGESR
EEECCEEEEECCCHHHHHHHCCCCCCCCCCCHHHHCCCCCCCCCCEEEEECCCCCCCCCE
IVTQLKPGAGVVTTRAHVQYVVTEYGIVNLHGKNLRQRAEALATIAHPDFREEILRQAHE
EEEEECCCCCEEEEHHHHEEEEECCCEEEECCHHHHHHHHHHHHHCCCCHHHHHHHHHHH
LYGRKSNCLID
HHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: propionyl-CoA; succinate [C]

Specific reaction: propionyl-CoA + succinate = propionate + succinyl-CoA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8550525 [H]