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The map label for this gene is galE [H]

Identifier: 21672865

GI number: 21672865

Start: 20271

End: 21260

Strand: Reverse

Name: galE [H]

Synonym: CT0024

Alternate gene names: 21672865

Gene position: 21260-20271 (Counterclockwise)

Preceding gene: 21672868

Following gene: 21672864

Centisome position: 0.99

GC content: 58.48

Gene sequence:

>990_bases
ATGAAAATTCTCGTTATCGGCGGCGCAGGGTATATCGGCAGTCATGTGGCTCGCGAGTTTCTCGACCGGGGCTACCAGGT
CACGGTGTTCGACAATCTCTCCACCGGTCGGGAGGAGAATCTTTTTGACGACGCGGAGTTTGTTCGTGGAGATATTTTCG
ACGCGGAAATGCTGGCCGAGGTGATGAATCGCGGGTTTGACGGCTGCGTTCATCTGGCGGCACTGAAGGCTGCCGGAGAG
TCGATGCAGAAGCCGGAGGAGTACTCCGTGCACAACATCTGCGGTACGATCGGCACCATCAACCAGGCGGTGGCAAGCGG
CATTAAATGCCTCCTCTTCTCCTCTTCGGCAGCCATTTTCGGCAGCCCGGCTTATTTGCCCATCGACGAGAATCATCCCA
AGAAGCCGGAAAACTACTACGGCTTCACCAAGCTCGAAATCGAGCGGATTCTCGAATGGTACGACCGGCTCAAGGGGCTG
AAGTTCGCGGCAGTCAGATATTTCAACGCCGCCGGATACGATGTGCGCGGGCGCATCCGAGGGCTGGAAAGGAATCCGGC
CAATCTGTTGCCGGTCATCATGGAGGTTGCGTCGGGCGTGAGGCCAATGCTCTCGGTGTTCGGCACCGACTACCCGACTC
GGGACGGCACCTGTATCCGCGACTATGTCCACGTCAACGATCTCGCTACCGCACACGTACTCGCGTTCGAGCAGGTAATC
GAGAGCGGCGAAAGCCTGTCGGTCAACCTCGGCAGCGAAACTGGCGTCACTGTGCTCGAAATGCTCGAAGCCGCGCGCCG
TTTGACAGGCAAAGAGATTATGGCAGAATTCGCGCCGCGTCGTGCGGGCGATCCGGCCAATCTGGTGGCAACCTCCGCGA
TGGCTCGCGAGTTGCTCGGCTGGGTTCCGCAGTACAGCGATCTGGACACGCTGGTTGAATCGACCTGGAATGTTTACCGG
GATGTTAACGCAGGTTCCGGCAGGCAATAG

Upstream 100 bases:

>100_bases
GAGCACAAGCAAATCACGCGTGGGCTCCACGTAAGTTATCTGGCGGGAAGTGTTATCTTTGGGCTTGATCGTGTATAAAC
CCCATATGAAATATTCAGGC

Downstream 100 bases:

>100_bases
CTATTACCCGATAGCGGCTCATGCCTCCAAAGGAGATGACCATGTTAGATAATGACAGGAAAAAGGATAAATTCTCCGAG
CAGTTTGGAGGAACGGTCAG

Product: UDP-glucose 4-epimerase

Products: NA

Alternate protein names: Galactowaldenase; UDP-galactose 4-epimerase [H]

Number of amino acids: Translated: 329; Mature: 329

Protein sequence:

>329_residues
MKILVIGGAGYIGSHVAREFLDRGYQVTVFDNLSTGREENLFDDAEFVRGDIFDAEMLAEVMNRGFDGCVHLAALKAAGE
SMQKPEEYSVHNICGTIGTINQAVASGIKCLLFSSSAAIFGSPAYLPIDENHPKKPENYYGFTKLEIERILEWYDRLKGL
KFAAVRYFNAAGYDVRGRIRGLERNPANLLPVIMEVASGVRPMLSVFGTDYPTRDGTCIRDYVHVNDLATAHVLAFEQVI
ESGESLSVNLGSETGVTVLEMLEAARRLTGKEIMAEFAPRRAGDPANLVATSAMARELLGWVPQYSDLDTLVESTWNVYR
DVNAGSGRQ

Sequences:

>Translated_329_residues
MKILVIGGAGYIGSHVAREFLDRGYQVTVFDNLSTGREENLFDDAEFVRGDIFDAEMLAEVMNRGFDGCVHLAALKAAGE
SMQKPEEYSVHNICGTIGTINQAVASGIKCLLFSSSAAIFGSPAYLPIDENHPKKPENYYGFTKLEIERILEWYDRLKGL
KFAAVRYFNAAGYDVRGRIRGLERNPANLLPVIMEVASGVRPMLSVFGTDYPTRDGTCIRDYVHVNDLATAHVLAFEQVI
ESGESLSVNLGSETGVTVLEMLEAARRLTGKEIMAEFAPRRAGDPANLVATSAMARELLGWVPQYSDLDTLVESTWNVYR
DVNAGSGRQ
>Mature_329_residues
MKILVIGGAGYIGSHVAREFLDRGYQVTVFDNLSTGREENLFDDAEFVRGDIFDAEMLAEVMNRGFDGCVHLAALKAAGE
SMQKPEEYSVHNICGTIGTINQAVASGIKCLLFSSSAAIFGSPAYLPIDENHPKKPENYYGFTKLEIERILEWYDRLKGL
KFAAVRYFNAAGYDVRGRIRGLERNPANLLPVIMEVASGVRPMLSVFGTDYPTRDGTCIRDYVHVNDLATAHVLAFEQVI
ESGESLSVNLGSETGVTVLEMLEAARRLTGKEIMAEFAPRRAGDPANLVATSAMARELLGWVPQYSDLDTLVESTWNVYR
DVNAGSGRQ

Specific function: Galactose metabolism; third step. [C]

COG id: COG1087

COG function: function code M; UDP-glucose 4-epimerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sugar epimerase family [H]

Homologues:

Organism=Homo sapiens, GI56237023, Length=348, Percent_Identity=39.367816091954, Blast_Score=216, Evalue=2e-56,
Organism=Homo sapiens, GI56118217, Length=348, Percent_Identity=39.367816091954, Blast_Score=216, Evalue=2e-56,
Organism=Homo sapiens, GI189083684, Length=348, Percent_Identity=39.367816091954, Blast_Score=216, Evalue=2e-56,
Organism=Homo sapiens, GI42516563, Length=315, Percent_Identity=26.984126984127, Blast_Score=93, Evalue=3e-19,
Organism=Escherichia coli, GI1786974, Length=328, Percent_Identity=37.5, Blast_Score=211, Evalue=4e-56,
Organism=Caenorhabditis elegans, GI71982035, Length=344, Percent_Identity=35.4651162790698, Blast_Score=192, Evalue=2e-49,
Organism=Caenorhabditis elegans, GI71982038, Length=346, Percent_Identity=35.2601156069364, Blast_Score=192, Evalue=2e-49,
Organism=Caenorhabditis elegans, GI17539532, Length=334, Percent_Identity=24.8502994011976, Blast_Score=80, Evalue=1e-15,
Organism=Saccharomyces cerevisiae, GI6319493, Length=321, Percent_Identity=38.6292834890966, Blast_Score=187, Evalue=2e-48,
Organism=Drosophila melanogaster, GI19923002, Length=336, Percent_Identity=39.2857142857143, Blast_Score=207, Evalue=8e-54,
Organism=Drosophila melanogaster, GI21356223, Length=341, Percent_Identity=25.2199413489736, Blast_Score=88, Evalue=8e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001509
- InterPro:   IPR005886
- InterPro:   IPR016040 [H]

Pfam domain/function: PF01370 Epimerase [H]

EC number: =5.1.3.2 [H]

Molecular weight: Translated: 36190; Mature: 36190

Theoretical pI: Translated: 4.82; Mature: 4.82

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKILVIGGAGYIGSHVAREFLDRGYQVTVFDNLSTGREENLFDDAEFVRGDIFDAEMLAE
CEEEEEECCCHHHHHHHHHHHHCCCEEEEECCCCCCCCCCCCCHHHHHHCCCCCHHHHHH
VMNRGFDGCVHLAALKAAGESMQKPEEYSVHNICGTIGTINQAVASGIKCLLFSSSAAIF
HHHCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCHHC
GSPAYLPIDENHPKKPENYYGFTKLEIERILEWYDRLKGLKFAAVRYFNAAGYDVRGRIR
CCCEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCHHHHHC
GLERNPANLLPVIMEVASGVRPMLSVFGTDYPTRDGTCIRDYVHVNDLATAHVLAFEQVI
CCCCCCHHHHHHHHHHHHCHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
ESGESLSVNLGSETGVTVLEMLEAARRLTGKEIMAEFAPRRAGDPANLVATSAMARELLG
HCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHH
WVPQYSDLDTLVESTWNVYRDVNAGSGRQ
HCCCCCHHHHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure
MKILVIGGAGYIGSHVAREFLDRGYQVTVFDNLSTGREENLFDDAEFVRGDIFDAEMLAE
CEEEEEECCCHHHHHHHHHHHHCCCEEEEECCCCCCCCCCCCCHHHHHHCCCCCHHHHHH
VMNRGFDGCVHLAALKAAGESMQKPEEYSVHNICGTIGTINQAVASGIKCLLFSSSAAIF
HHHCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCHHC
GSPAYLPIDENHPKKPENYYGFTKLEIERILEWYDRLKGLKFAAVRYFNAAGYDVRGRIR
CCCEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCHHHHHC
GLERNPANLLPVIMEVASGVRPMLSVFGTDYPTRDGTCIRDYVHVNDLATAHVLAFEQVI
CCCCCCHHHHHHHHHHHHCHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
ESGESLSVNLGSETGVTVLEMLEAARRLTGKEIMAEFAPRRAGDPANLVATSAMARELLG
HCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHH
WVPQYSDLDTLVESTWNVYRDVNAGSGRQ
HCCCCCHHHHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9603808 [H]