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The map label for this gene is dinB3

Identifier: 13488542

GI number: 13488542

Start: 169772

End: 170857

Strand: Reverse

Name: dinB3

Synonym: mll9709

Alternate gene names: 13488542

Gene position: 170857-169772 (Counterclockwise)

Preceding gene: 13488543

Following gene: 13488529

Centisome position: 82.02

GC content: 61.6

Gene sequence:

>1086_bases
ATGGTCCCTGAACGCGGCGCCGACCCTCGCAAGATCATCCATGTCGACATGGATGCATTCTATGCGTCGGTCGAACAGCG
CGACAATCCAGAACTGCGCGGCAAGCCGCTTGCCGTCGGCGGCGCCGCCGCCCGCGGCGTGGTTGCTGCCGCAAGTTACG
AGGCCCGAGCCTTTGGTGTTCGCTCCGCGATGCCTTCGGTCACGGCAAAGCGCAAATGCCCCGAACTGATCTTCGTGCCG
CCCCGATTCGACGTCTACCGGGCGGTCTCGGCTCAGATCCGAGACGTGTTCGCCGAACACACCGATCTCATCGAGCCGCT
CTCGCTTGACGAGGCCTATCTCGACGTGACGCAGAACCGGCTCAACATTTCGTCTGCCACGACGATCGCCGAGATGATCA
GGGCGAAGATCCTGGAGGTGACCGGTCTCACCGCTTCCGCGGGCATTTCGTACAACAAATTTCTCGCCAAGATGGCGTCC
GACCAGAACAAGCCGAACGGCCAGTTCGTCATCACGCCACGCCACGGGCCGGCCTTCGTGGAAACCTTGCCGGTCAACAA
ATTTCATGGTGTCGGTCCTGCGACAGCCGCGAAGATGGAGGCGCTCGGCATTGAGACCGGCGCTGATCTCAAGGAAAGGT
CCCTTTCCTTCCTGCAGCAGCATTTTGGAAAGTCGGGGCTCTGGTACTATCAGATCGCGCGCGCCATCGACGAACGTGCG
GTCGATCCGGATCGGCCACGCAAATCGATCGGCGCCGAGGACACGTTCGCAGCCGACATCGTCGATCTCGAAACATCGCT
CGCCGAACTCAAGCCGCTGGTGGCCAAAGTGTGGGGATACTGTGAGGGCAAAGGCATCCGGGGCCGGACCGTCACGCTGA
AGATCAAATTTGCCGACTTCCAGCAGATCACGCGCAGCCGGACTGTGGCGGTGCCGATCGAACTTTCCGACTTCGAGCAT
CTCGCAGCCGATCTCCTTGGATCGGTGTTTCCGGTGCGGAAGGGAATCCGCCTGTTGGGCGTGACGCTTTCGTCGCTGGG
CGACGTGTTGCCGCCGGATCAGCGGCAGTTGCGGTTCGAACTCTAG

Upstream 100 bases:

>100_bases
CATCTGCGCCAGGCTCGCAAACAGGCTGAATTTGCGATCTGAAGATTGTAGGATCTTTCAATACGAGGCTTAGACCCTGG
TGAAATGATATTGCAGGCAA

Downstream 100 bases:

>100_bases
GTATCTCCACGGCCGGGGGAAAAACCAACCGCAGGCTCTCAGTGTCAACGCGCATGCGGATCGATTTCGCGAACGATCTG
TGAGGCTTCTCCGTCATACT

Product: DNA polymerase IV

Products: NA

Alternate protein names: Pol IV 3

Number of amino acids: Translated: 361; Mature: 361

Protein sequence:

>361_residues
MVPERGADPRKIIHVDMDAFYASVEQRDNPELRGKPLAVGGAAARGVVAAASYEARAFGVRSAMPSVTAKRKCPELIFVP
PRFDVYRAVSAQIRDVFAEHTDLIEPLSLDEAYLDVTQNRLNISSATTIAEMIRAKILEVTGLTASAGISYNKFLAKMAS
DQNKPNGQFVITPRHGPAFVETLPVNKFHGVGPATAAKMEALGIETGADLKERSLSFLQQHFGKSGLWYYQIARAIDERA
VDPDRPRKSIGAEDTFAADIVDLETSLAELKPLVAKVWGYCEGKGIRGRTVTLKIKFADFQQITRSRTVAVPIELSDFEH
LAADLLGSVFPVRKGIRLLGVTLSSLGDVLPPDQRQLRFEL

Sequences:

>Translated_361_residues
MVPERGADPRKIIHVDMDAFYASVEQRDNPELRGKPLAVGGAAARGVVAAASYEARAFGVRSAMPSVTAKRKCPELIFVP
PRFDVYRAVSAQIRDVFAEHTDLIEPLSLDEAYLDVTQNRLNISSATTIAEMIRAKILEVTGLTASAGISYNKFLAKMAS
DQNKPNGQFVITPRHGPAFVETLPVNKFHGVGPATAAKMEALGIETGADLKERSLSFLQQHFGKSGLWYYQIARAIDERA
VDPDRPRKSIGAEDTFAADIVDLETSLAELKPLVAKVWGYCEGKGIRGRTVTLKIKFADFQQITRSRTVAVPIELSDFEH
LAADLLGSVFPVRKGIRLLGVTLSSLGDVLPPDQRQLRFEL
>Mature_361_residues
MVPERGADPRKIIHVDMDAFYASVEQRDNPELRGKPLAVGGAAARGVVAAASYEARAFGVRSAMPSVTAKRKCPELIFVP
PRFDVYRAVSAQIRDVFAEHTDLIEPLSLDEAYLDVTQNRLNISSATTIAEMIRAKILEVTGLTASAGISYNKFLAKMAS
DQNKPNGQFVITPRHGPAFVETLPVNKFHGVGPATAAKMEALGIETGADLKERSLSFLQQHFGKSGLWYYQIARAIDERA
VDPDRPRKSIGAEDTFAADIVDLETSLAELKPLVAKVWGYCEGKGIRGRTVTLKIKFADFQQITRSRTVAVPIELSDFEH
LAADLLGSVFPVRKGIRLLGVTLSSLGDVLPPDQRQLRFEL

Specific function: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits

COG id: COG0389

COG function: function code L; Nucleotidyltransferase/DNA polymerase involved in DNA repair

Gene ontology:

Cell location: Cytoplasm (Probable)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 umuC domain

Homologues:

Organism=Homo sapiens, GI7705344, Length=422, Percent_Identity=31.9905213270142, Blast_Score=179, Evalue=3e-45,
Organism=Homo sapiens, GI7706681, Length=366, Percent_Identity=30.327868852459, Blast_Score=158, Evalue=6e-39,
Organism=Homo sapiens, GI84043967, Length=365, Percent_Identity=30.1369863013699, Blast_Score=158, Evalue=9e-39,
Organism=Homo sapiens, GI5729982, Length=320, Percent_Identity=32.1875, Blast_Score=134, Evalue=2e-31,
Organism=Homo sapiens, GI154350220, Length=351, Percent_Identity=29.6296296296296, Blast_Score=133, Evalue=2e-31,
Organism=Escherichia coli, GI1786425, Length=376, Percent_Identity=44.9468085106383, Blast_Score=279, Evalue=2e-76,
Organism=Escherichia coli, GI1787432, Length=218, Percent_Identity=32.1100917431193, Blast_Score=102, Evalue=5e-23,
Organism=Caenorhabditis elegans, GI193205700, Length=397, Percent_Identity=30.2267002518892, Blast_Score=154, Evalue=7e-38,
Organism=Caenorhabditis elegans, GI17537959, Length=373, Percent_Identity=26.2734584450402, Blast_Score=105, Evalue=5e-23,
Organism=Caenorhabditis elegans, GI193205702, Length=218, Percent_Identity=35.3211009174312, Blast_Score=100, Evalue=8e-22,
Organism=Caenorhabditis elegans, GI115534089, Length=166, Percent_Identity=36.144578313253, Blast_Score=85, Evalue=7e-17,
Organism=Drosophila melanogaster, GI19923006, Length=406, Percent_Identity=27.5862068965517, Blast_Score=144, Evalue=9e-35,
Organism=Drosophila melanogaster, GI21355641, Length=316, Percent_Identity=30.379746835443, Blast_Score=121, Evalue=8e-28,
Organism=Drosophila melanogaster, GI24644984, Length=316, Percent_Identity=30.379746835443, Blast_Score=121, Evalue=8e-28,
Organism=Drosophila melanogaster, GI24668444, Length=258, Percent_Identity=28.6821705426357, Blast_Score=83, Evalue=2e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): DPO43_RHILO (Q98NW7)

Other databases:

- EMBL:   AP003017
- RefSeq:   NP_109549.1
- ProteinModelPortal:   Q98NW7
- SMR:   Q98NW7
- GeneID:   1224521
- GenomeReviews:   AP003017_GR
- KEGG:   mlo:mll9709
- NMPDR:   fig|266835.1.peg.7238
- HOGENOM:   HBG734504
- OMA:   QAMARQE
- ProtClustDB:   PRK02406
- BRENDA:   2.7.7.7
- GO:   GO:0005737
- HAMAP:   MF_01113
- InterPro:   IPR017962
- InterPro:   IPR017961
- InterPro:   IPR001126
- InterPro:   IPR017963
- InterPro:   IPR022880
- Gene3D:   G3DSA:3.30.1490.100
- PANTHER:   PTHR11076

Pfam domain/function: PF00817 IMS; SSF100879 DNA_pol_Y-fam_little_finger

EC number: =2.7.7.7

Molecular weight: Translated: 39532; Mature: 39532

Theoretical pI: Translated: 8.63; Mature: 8.63

Prosite motif: PS50173 UMUC

Important sites: ACT_SITE 111-111

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVPERGADPRKIIHVDMDAFYASVEQRDNPELRGKPLAVGGAAARGVVAAASYEARAFGV
CCCCCCCCCCEEEEEEHHHHHHHHHHCCCCCCCCCCEEECCHHHHCCCEECCCHHHHHHH
RSAMPSVTAKRKCPELIFVPPRFDVYRAVSAQIRDVFAEHTDLIEPLSLDEAYLDVTQNR
HHHCCCHHHHHCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCC
LNISSATTIAEMIRAKILEVTGLTASAGISYNKFLAKMASDQNKPNGQFVITPRHGPAFV
CCCHHHHHHHHHHHHHHHHHCCCCHHCCCCHHHHHHHHHHCCCCCCCEEEEECCCCCCEE
ETLPVNKFHGVGPATAAKMEALGIETGADLKERSLSFLQQHFGKSGLWYYQIARAIDERA
EEECCCCCCCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHC
VDPDRPRKSIGAEDTFAADIVDLETSLAELKPLVAKVWGYCEGKGIRGRTVTLKIKFADF
CCCCCCHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEEEECHH
QQITRSRTVAVPIELSDFEHLAADLLGSVFPVRKGIRLLGVTLSSLGDVLPPDQRQLRFE
HHHHHCCEEEEEEECCHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHCCCCCCCCHHHEEC
L
C
>Mature Secondary Structure
MVPERGADPRKIIHVDMDAFYASVEQRDNPELRGKPLAVGGAAARGVVAAASYEARAFGV
CCCCCCCCCCEEEEEEHHHHHHHHHHCCCCCCCCCCEEECCHHHHCCCEECCCHHHHHHH
RSAMPSVTAKRKCPELIFVPPRFDVYRAVSAQIRDVFAEHTDLIEPLSLDEAYLDVTQNR
HHHCCCHHHHHCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCC
LNISSATTIAEMIRAKILEVTGLTASAGISYNKFLAKMASDQNKPNGQFVITPRHGPAFV
CCCHHHHHHHHHHHHHHHHHCCCCHHCCCCHHHHHHHHHHCCCCCCCEEEEECCCCCCEE
ETLPVNKFHGVGPATAAKMEALGIETGADLKERSLSFLQQHFGKSGLWYYQIARAIDERA
EEECCCCCCCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHC
VDPDRPRKSIGAEDTFAADIVDLETSLAELKPLVAKVWGYCEGKGIRGRTVTLKIKFADF
CCCCCCHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEEEECHH
QQITRSRTVAVPIELSDFEHLAADLLGSVFPVRKGIRLLGVTLSSLGDVLPPDQRQLRFE
HHHHHCCEEEEEEECCHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHCCCCCCCCHHHEEC
L
C

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11214968