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The map label for this gene is yegS [C]

Identifier: 13488518

GI number: 13488518

Start: 142412

End: 143854

Strand: Reverse

Name: yegS [C]

Synonym: mll9677

Alternate gene names: 13488518

Gene position: 143854-142412 (Counterclockwise)

Preceding gene: 13488519

Following gene: 13488517

Centisome position: 69.06

GC content: 59.53

Gene sequence:

>1443_bases
ATGGCTTCAGGAAGCGGCCAGGGATGTGACCTCGTTCGGCAGCATGGTGTTTCTTGGCTTCGTGCTGCTGGCAGCGGTTG
TTTATCTGCTTCTGGTCCACAAGCGGGCACTGGCCATTTGGATGGCGGTGGCGGTGGCCGGCGGCGAACTGCTTGGCACG
ATCCTCAAGCTGAGCTTCAACCGGCCCAGGCCGGAAATTCCTCATGTCACGCGAGTATTCACGGCAAGCTTCCCGAGTGG
ACATGCAATGCTCTCGGCGATCACGTTCCTGACCGTAGGCGCTCTCCTTTCACATGCAAGTCAGGATCTGCGCCTCAAAG
TGTATTTCATGTTGCTTGCCGTGTTTCTGACGGTGGCCGTTGGCATAAGCCGGGTCTATCTGGCGGTCCACTATCCTACG
GATGTCTTGGCCGGATGGTGCGTTGGCTCTGGCTGGGCGGTCCTGTGCTGGATAGTCGCTTTATGGTTTCAGGAAAGGCC
GAAGCGGGGGCCAAAGACTTGAAGGTTATGGCGCTCATCAACAAAAGGGCCGGCGCTGCGGCGCGCGAGGGCGACATAGA
GAGAGCCGTGCGGGATGGGTTCGCCGAACGTGGCGTCGAGGCCGATGTGCGATTGGTAGAAGGGCGAGAGGTGGGAGAGC
TCGCTCAGCGCTTTGTTGCCGAAAACAAGTCGAGCTCCGGCCATGGATCGATATTGGTGGTGGGCGGCGGCGACGGCACT
CTCGGCAGCGCCGCCTCCGCGCTGGCGGGGACGGATGTGGTGCTCGGTGTTCTTCCGCTCGGCACGTTAAACCACTTTGC
CAAGGATTTGGGTGTGCCGCTCGACCTGACGGCGGCGATCGATACAATCGCGACCGGCAAGCCTGTCGCGGTCGATGTCG
CCGAGGTCAACGGCCGCGTCTTTCTCAACAACTCATCGATCGGCATCTATCCCTTCTTTGTAGCAAAGCGTTCAGCCGAG
CAGCGGCGCCGCGGGTTAGGCAAGCTCGCGGCTATCGGACCCGCTCTGATGAGAACGTTGAGATTCGCCTCCTGGCAGGC
TGTCCACGTCGCCGCCCAGGGTACCCGCGAAAGACTGCGGACGCCCTGCGTGTTTGTTGGCAACAATTTCTACGACATCG
CCGATCTTGGCCGCCGCCGCAGCCTGTCGTCGAAAGAGCTGTGCGTTTATGTCGTCAAGCAGCAGTCCTGGTTTGGACTG
GCATTGCTTCCGTTCAAGATCGCCTTCGGCATGGTCGACGCCACACGAGATCTGGAAATCTATCGCACCAATTCGCTCCA
AATCACATCGCATAGACGCGCCATGCTGATCTCTCTGGACGGCGAAGCCGTCAGTATAAACACGCCCCTGAATTTTCAGA
TTCGGCCAGCGGCTCTGCAGGTCTTCGCACCTGCCAAAATACCGGAACCGGTGGTCGTAGCTGAAAGCGGAGAAATTCAG
TGA

Upstream 100 bases:

>100_bases
TGCTCGCCGAGGAAGTCCTGGAAGGCGATACAACCAAATTTGATATGGCCATTATGTCGACCCTTCGCGCAGCCGATCCG
GCCTACCCGATCGGTCCACC

Downstream 100 bases:

>100_bases
AGACCCTCGTCCACCTTTCGGATTTGCACTTCGGAAAAACAGAAAGCCAGCTTGTGGACGCGATCGCGGCTGAGGTTCGT
GCCGTCGACTCTGATTTGCT

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 480; Mature: 479

Protein sequence:

>480_residues
MASGSGQGCDLVRQHGVSWLRAAGSGCLSASGPQAGTGHLDGGGGGRRRTAWHDPQAELQPAQAGNSSCHASIHGKLPEW
TCNALGDHVPDRRRSPFTCKSGSAPQSVFHVACRVSDGGRWHKPGLSGGPLSYGCLGRMVRWLWLGGPVLDSRFMVSGKA
EAGAKDLKVMALINKRAGAAAREGDIERAVRDGFAERGVEADVRLVEGREVGELAQRFVAENKSSSGHGSILVVGGGDGT
LGSAASALAGTDVVLGVLPLGTLNHFAKDLGVPLDLTAAIDTIATGKPVAVDVAEVNGRVFLNNSSIGIYPFFVAKRSAE
QRRRGLGKLAAIGPALMRTLRFASWQAVHVAAQGTRERLRTPCVFVGNNFYDIADLGRRRSLSSKELCVYVVKQQSWFGL
ALLPFKIAFGMVDATRDLEIYRTNSLQITSHRRAMLISLDGEAVSINTPLNFQIRPAALQVFAPAKIPEPVVVAESGEIQ

Sequences:

>Translated_480_residues
MASGSGQGCDLVRQHGVSWLRAAGSGCLSASGPQAGTGHLDGGGGGRRRTAWHDPQAELQPAQAGNSSCHASIHGKLPEW
TCNALGDHVPDRRRSPFTCKSGSAPQSVFHVACRVSDGGRWHKPGLSGGPLSYGCLGRMVRWLWLGGPVLDSRFMVSGKA
EAGAKDLKVMALINKRAGAAAREGDIERAVRDGFAERGVEADVRLVEGREVGELAQRFVAENKSSSGHGSILVVGGGDGT
LGSAASALAGTDVVLGVLPLGTLNHFAKDLGVPLDLTAAIDTIATGKPVAVDVAEVNGRVFLNNSSIGIYPFFVAKRSAE
QRRRGLGKLAAIGPALMRTLRFASWQAVHVAAQGTRERLRTPCVFVGNNFYDIADLGRRRSLSSKELCVYVVKQQSWFGL
ALLPFKIAFGMVDATRDLEIYRTNSLQITSHRRAMLISLDGEAVSINTPLNFQIRPAALQVFAPAKIPEPVVVAESGEIQ
>Mature_479_residues
ASGSGQGCDLVRQHGVSWLRAAGSGCLSASGPQAGTGHLDGGGGGRRRTAWHDPQAELQPAQAGNSSCHASIHGKLPEWT
CNALGDHVPDRRRSPFTCKSGSAPQSVFHVACRVSDGGRWHKPGLSGGPLSYGCLGRMVRWLWLGGPVLDSRFMVSGKAE
AGAKDLKVMALINKRAGAAAREGDIERAVRDGFAERGVEADVRLVEGREVGELAQRFVAENKSSSGHGSILVVGGGDGTL
GSAASALAGTDVVLGVLPLGTLNHFAKDLGVPLDLTAAIDTIATGKPVAVDVAEVNGRVFLNNSSIGIYPFFVAKRSAEQ
RRRGLGKLAAIGPALMRTLRFASWQAVHVAAQGTRERLRTPCVFVGNNFYDIADLGRRRSLSSKELCVYVVKQQSWFGLA
LLPFKIAFGMVDATRDLEIYRTNSLQITSHRRAMLISLDGEAVSINTPLNFQIRPAALQVFAPAKIPEPVVVAESGEIQ

Specific function: Probably phosphorylates lipids; the in vivo substrate is unknown [H]

COG id: COG1597

COG function: function code IR; Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 DAGKc domain [H]

Homologues:

Organism=Escherichia coli, GI1788402, Length=289, Percent_Identity=26.9896193771626, Blast_Score=69, Evalue=8e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005218
- InterPro:   IPR001206
- InterPro:   IPR022433
- InterPro:   IPR022862 [H]

Pfam domain/function: PF00781 DAGK_cat [H]

EC number: NA

Molecular weight: Translated: 50854; Mature: 50722

Theoretical pI: Translated: 9.84; Mature: 9.84

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MASGSGQGCDLVRQHGVSWLRAAGSGCLSASGPQAGTGHLDGGGGGRRRTAWHDPQAELQ
CCCCCCCCHHHHHHCCHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
PAQAGNSSCHASIHGKLPEWTCNALGDHVPDRRRSPFTCKSGSAPQSVFHVACRVSDGGR
CCCCCCCCEEEEECCCCCCCCHHHHHCCCCCCCCCCCCCCCCCCHHHEEEEEEEECCCCC
WHKPGLSGGPLSYGCLGRMVRWLWLGGPVLDSRFMVSGKAEAGAKDLKVMALINKRAGAA
CCCCCCCCCCCCHHHHHHHHHHHHCCCCHHCCEEEEECCCCCCCCCEEEEEEECCCCCCC
AREGDIERAVRDGFAERGVEADVRLVEGREVGELAQRFVAENKSSSGHGSILVVGGGDGT
CCCCHHHHHHHHHHHHCCCCCCEEEECCCCHHHHHHHHHHCCCCCCCCCEEEEEECCCCC
LGSAASALAGTDVVLGVLPLGTLNHFAKDLGVPLDLTAAIDTIATGKPVAVDVAEVNGRV
CHHHHHHHCCCHHEEEHHCHHHHHHHHHHHCCCEEHHHHHHHHCCCCCEEEEEEECCCEE
FLNNSSIGIYPFFVAKRSAEQRRRGLGKLAAIGPALMRTLRFASWQAVHVAAQGTRERLR
EEECCCCEEEEEEEHHCCHHHHHHCCHHHHHHHHHHHHHHHHCCCEEEEEEHHCCHHHHC
TPCVFVGNNFYDIADLGRRRSLSSKELCVYVVKQQSWFGLALLPFKIAFGMVDATRDLEI
CCEEEECCCEEEHHHHHHHCCCCCCCEEEEEEECCCCCCEEHHHHHHHHHHHCCCCCEEE
YRTNSLQITSHRRAMLISLDGEAVSINTPLNFQIRPAALQVFAPAKIPEPVVVAESGEIQ
EEECCEEEECCCEEEEEEECCCEEEECCCCCEEECCCEEEEEECCCCCCCEEEECCCCCC
>Mature Secondary Structure 
ASGSGQGCDLVRQHGVSWLRAAGSGCLSASGPQAGTGHLDGGGGGRRRTAWHDPQAELQ
CCCCCCCHHHHHHCCHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
PAQAGNSSCHASIHGKLPEWTCNALGDHVPDRRRSPFTCKSGSAPQSVFHVACRVSDGGR
CCCCCCCCEEEEECCCCCCCCHHHHHCCCCCCCCCCCCCCCCCCHHHEEEEEEEECCCCC
WHKPGLSGGPLSYGCLGRMVRWLWLGGPVLDSRFMVSGKAEAGAKDLKVMALINKRAGAA
CCCCCCCCCCCCHHHHHHHHHHHHCCCCHHCCEEEEECCCCCCCCCEEEEEEECCCCCCC
AREGDIERAVRDGFAERGVEADVRLVEGREVGELAQRFVAENKSSSGHGSILVVGGGDGT
CCCCHHHHHHHHHHHHCCCCCCEEEECCCCHHHHHHHHHHCCCCCCCCCEEEEEECCCCC
LGSAASALAGTDVVLGVLPLGTLNHFAKDLGVPLDLTAAIDTIATGKPVAVDVAEVNGRV
CHHHHHHHCCCHHEEEHHCHHHHHHHHHHHCCCEEHHHHHHHHCCCCCEEEEEEECCCEE
FLNNSSIGIYPFFVAKRSAEQRRRGLGKLAAIGPALMRTLRFASWQAVHVAAQGTRERLR
EEECCCCEEEEEEEHHCCHHHHHHCCHHHHHHHHHHHHHHHHCCCEEEEEEHHCCHHHHC
TPCVFVGNNFYDIADLGRRRSLSSKELCVYVVKQQSWFGLALLPFKIAFGMVDATRDLEI
CCEEEECCCEEEHHHHHHHCCCCCCCEEEEEEECCCCCCEEHHHHHHHHHHHCCCCCEEE
YRTNSLQITSHRRAMLISLDGEAVSINTPLNFQIRPAALQVFAPAKIPEPVVVAESGEIQ
EEECCEEEECCCEEEEEEECCCEEEECCCCCEEECCCEEEEEECCCCCCCEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA