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The map label for this gene is ctaD [H]

Identifier: 13488474

GI number: 13488474

Start: 96358

End: 98229

Strand: Reverse

Name: ctaD [H]

Synonym: mll9630

Alternate gene names: 13488474

Gene position: 98229-96358 (Counterclockwise)

Preceding gene: 13488475

Following gene: 13488473

Centisome position: 47.15

GC content: 60.79

Gene sequence:

>1872_bases
ATGGAAGCCGGCGAACTCGATCGTCGACTTGCCGCGACCTGGTCAACACCCCCTGGCCTGTGGGGTGCCCTGTCGACGGT
CGATCATAAGATTATCGGCCGCCGATACACCGTCACGGCGTTTGTCTTCCTGGCACTTGGCGGAGTGCTGGCTTTGCTGA
TGCGGCTGCAGCTGGCGCAACCCGAAGCCCGGTTCATCGGGCCCGATCGCTACAACCAGATTTTCACCATGCACGGCTCG
AACATGATGTTCCTGTTCGCCGTGCCGGTCATGCAGGCGATGGCGATCTACCTCGTGCCCTTGATGGTGGGGACCCGACA
CATCGCATTCCCGCGCCTCAACGCGTTCTCCTACTGGATGTACCTTGCCGGCGGCCTGCTGTTGTGGATCGCCTTCGCCG
TCGATACCGGTCCGGACATTGGATGGTTCGCCTACGTACCGCTGTCGGGGCCTCAATATGCAGCCGGGAAGCGGGCCGAC
ATATGGGCCCAGATGATCACCTTTACCGAGGTTTCCGCTCTCGCCATCGCCGTCGAAATCGTCGTCACCGTATTCAAGCA
ACGCGCCCCGGGAATGTCACTGGACAGGATTCCGCTGTTCGTCTGGTCGATGCTGGTCACGTCCTTCCTGGTCATCCTCG
CCATGCCGGCGATCATGATCGCCAGCACCAGCCTGATCCTCGATCGGCTCGTGGGGACGCATTTCTTCAACCCGGCCGAA
GGCGGTGACGTGCTGCTGTGGCAGCATCTGTTCTGGTTCTTCGGCCACCCTGAGGTCTATATCATCTTCCTGCCGGCGGT
GGGCATGGTCTCGAGCATCGTCGCCACATTCACACAGCGTCCGGTGTTCGGCTATCTGGCCATGGTGATGGCCTTGATCG
CGACGGGCGTTCTCGCCTTCGGGCTGTGGGTGCATCATATGTTCGTGGCCGGCCTCCCGCGGCTGGGCGAAAGCTTCTTC
ACCGCCTCAAGCATGGCGATCGCCGTTCCCGCAGGCCTGCAAATCTTCTGCTGGCTGGCGACGATCTGGGCCGGACGGCC
AATCTTCAAGACGCCGTTTTTGTTCGTCATCGGGTTCATCGTCGTGTTCGTCATTGGTGGGCTGACCGGTGTGATGGTGG
CATCGGTTCCGTTCGATACCCAGGTTCACGACACCTATTTCGTCGTCGCGCATTTCCACTACGTCCTGGTCGGTGGCGCC
GTGTTTCCCCTGCTGGGCGCGATCTATTACTGGTTTCCGAAACTGACGGGCCGAATGATGAGCGAGACGCTTGGCCGCTG
GTCGTTTGGCCTCATCTTCTCGGGTTTCAATCTGACTTTCTTCCCCATGCACATTCTCGGCCTGCAAGGCATGCCGCGGC
GCATCTACACCTATCAGCCGGAGATGCCGTGGTCCGGCCTGAACATGTTCATCAGTCTCAGCGGGATCGTTCTGGCCGCC
GGTTTCCTGCTGTTCTTCATCGACGCCATACGCAGCGCCAGATCAGGTCCCATCGCACCAGCCAATCCGTGGGGGGCCTC
GACGCTGGAGTGGGCGACGTCTTCGCCACCGCCGTCCTATAATTTCGCGCGGCTGCCTGTCGTCGAAAGCCTAGAGCCCT
TGTCGGACAGATCGGACCCACTTGGTACCGTCGAGGGTCTGCACACGGACCGGCGCGAACTGCTTATCACCAGTGTCGTG
GAAGCGCGTGCGGAAGCGCGTGAATCATCGGTCGGGAATTCGATTTGGCCGCTCCTGGCGGCGCTCGCTACGTCAGCAAT
GCTGATTTGGTCGATCTTTACCCCATGGGCCGTGGTCTGGGGCTCCATACCGATTGCAGTCGCACTCATTGGCTGGTTCT
GGCCAAAGGGCGACCCGGAGGATGAGTCATGA

Upstream 100 bases:

>100_bases
TGGTCCCGCTGACCAGCATCGAGCTCCAGAATATCTGCGCCTATATGGATAGTCTCAAATGAGTGCAGCAGCGGATCGCG
AAGGGGTTCGGGACACCGGG

Downstream 100 bases:

>100_bases
AGCATGTGCCCAAGCCGCTGATTTGCTAGCTACTCGTCGGCCGGATGTCGCAGTTCTGGACGTACTCCTTAGCGACGGCC
AATGCGTCGATGTAGCGAAG

Product: cytochrome C oxidase subunit I

Products: NA

Alternate protein names: Caa-3605 subunit 1; Cytochrome aa3 subunit 1; Cytochrome c oxidase polypeptide I; Oxidase aa(3) subunit 1 [H]

Number of amino acids: Translated: 623; Mature: 623

Protein sequence:

>623_residues
MEAGELDRRLAATWSTPPGLWGALSTVDHKIIGRRYTVTAFVFLALGGVLALLMRLQLAQPEARFIGPDRYNQIFTMHGS
NMMFLFAVPVMQAMAIYLVPLMVGTRHIAFPRLNAFSYWMYLAGGLLLWIAFAVDTGPDIGWFAYVPLSGPQYAAGKRAD
IWAQMITFTEVSALAIAVEIVVTVFKQRAPGMSLDRIPLFVWSMLVTSFLVILAMPAIMIASTSLILDRLVGTHFFNPAE
GGDVLLWQHLFWFFGHPEVYIIFLPAVGMVSSIVATFTQRPVFGYLAMVMALIATGVLAFGLWVHHMFVAGLPRLGESFF
TASSMAIAVPAGLQIFCWLATIWAGRPIFKTPFLFVIGFIVVFVIGGLTGVMVASVPFDTQVHDTYFVVAHFHYVLVGGA
VFPLLGAIYYWFPKLTGRMMSETLGRWSFGLIFSGFNLTFFPMHILGLQGMPRRIYTYQPEMPWSGLNMFISLSGIVLAA
GFLLFFIDAIRSARSGPIAPANPWGASTLEWATSSPPPSYNFARLPVVESLEPLSDRSDPLGTVEGLHTDRRELLITSVV
EARAEARESSVGNSIWPLLAALATSAMLIWSIFTPWAVVWGSIPIAVALIGWFWPKGDPEDES

Sequences:

>Translated_623_residues
MEAGELDRRLAATWSTPPGLWGALSTVDHKIIGRRYTVTAFVFLALGGVLALLMRLQLAQPEARFIGPDRYNQIFTMHGS
NMMFLFAVPVMQAMAIYLVPLMVGTRHIAFPRLNAFSYWMYLAGGLLLWIAFAVDTGPDIGWFAYVPLSGPQYAAGKRAD
IWAQMITFTEVSALAIAVEIVVTVFKQRAPGMSLDRIPLFVWSMLVTSFLVILAMPAIMIASTSLILDRLVGTHFFNPAE
GGDVLLWQHLFWFFGHPEVYIIFLPAVGMVSSIVATFTQRPVFGYLAMVMALIATGVLAFGLWVHHMFVAGLPRLGESFF
TASSMAIAVPAGLQIFCWLATIWAGRPIFKTPFLFVIGFIVVFVIGGLTGVMVASVPFDTQVHDTYFVVAHFHYVLVGGA
VFPLLGAIYYWFPKLTGRMMSETLGRWSFGLIFSGFNLTFFPMHILGLQGMPRRIYTYQPEMPWSGLNMFISLSGIVLAA
GFLLFFIDAIRSARSGPIAPANPWGASTLEWATSSPPPSYNFARLPVVESLEPLSDRSDPLGTVEGLHTDRRELLITSVV
EARAEARESSVGNSIWPLLAALATSAMLIWSIFTPWAVVWGSIPIAVALIGWFWPKGDPEDES
>Mature_623_residues
MEAGELDRRLAATWSTPPGLWGALSTVDHKIIGRRYTVTAFVFLALGGVLALLMRLQLAQPEARFIGPDRYNQIFTMHGS
NMMFLFAVPVMQAMAIYLVPLMVGTRHIAFPRLNAFSYWMYLAGGLLLWIAFAVDTGPDIGWFAYVPLSGPQYAAGKRAD
IWAQMITFTEVSALAIAVEIVVTVFKQRAPGMSLDRIPLFVWSMLVTSFLVILAMPAIMIASTSLILDRLVGTHFFNPAE
GGDVLLWQHLFWFFGHPEVYIIFLPAVGMVSSIVATFTQRPVFGYLAMVMALIATGVLAFGLWVHHMFVAGLPRLGESFF
TASSMAIAVPAGLQIFCWLATIWAGRPIFKTPFLFVIGFIVVFVIGGLTGVMVASVPFDTQVHDTYFVVAHFHYVLVGGA
VFPLLGAIYYWFPKLTGRMMSETLGRWSFGLIFSGFNLTFFPMHILGLQGMPRRIYTYQPEMPWSGLNMFISLSGIVLAA
GFLLFFIDAIRSARSGPIAPANPWGASTLEWATSSPPPSYNFARLPVVESLEPLSDRSDPLGTVEGLHTDRRELLITSVV
EARAEARESSVGNSIWPLLAALATSAMLIWSIFTPWAVVWGSIPIAVALIGWFWPKGDPEDES

Specific function: Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. Co I is the catalytic subunit of the enzyme. Electrons originating in cytochrome

COG id: COG0843

COG function: function code C; Heme/copper-type cytochrome/quinol oxidases, subunit 1

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the heme-copper respiratory oxidase family [H]

Homologues:

Organism=Homo sapiens, GI251831109, Length=508, Percent_Identity=39.5669291338583, Blast_Score=343, Evalue=3e-94,
Organism=Escherichia coli, GI1786634, Length=523, Percent_Identity=38.4321223709369, Blast_Score=376, Evalue=1e-105,
Organism=Saccharomyces cerevisiae, GI6226519, Length=534, Percent_Identity=37.0786516853933, Blast_Score=350, Evalue=3e-97,
Organism=Saccharomyces cerevisiae, GI6226524, Length=296, Percent_Identity=38.5135135135135, Blast_Score=226, Evalue=7e-60,
Organism=Saccharomyces cerevisiae, GI6226523, Length=222, Percent_Identity=36.9369369369369, Blast_Score=135, Evalue=2e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000883
- InterPro:   IPR014241 [H]

Pfam domain/function: PF00115 COX1 [H]

EC number: =1.9.3.1 [H]

Molecular weight: Translated: 68738; Mature: 68738

Theoretical pI: Translated: 7.02; Mature: 7.02

Prosite motif: PS50855 COX1 ; PS00077 COX1_CUB

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEAGELDRRLAATWSTPPGLWGALSTVDHKIIGRRYTVTAFVFLALGGVLALLMRLQLAQ
CCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCC
PEARFIGPDRYNQIFTMHGSNMMFLFAVPVMQAMAIYLVPLMVGTRHIAFPRLNAFSYWM
CCHHCCCCCHHCEEEEEECCCEEEHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHH
YLAGGLLLWIAFAVDTGPDIGWFAYVPLSGPQYAAGKRADIWAQMITFTEVSALAIAVEI
HHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
VVTVFKQRAPGMSLDRIPLFVWSMLVTSFLVILAMPAIMIASTSLILDRLVGTHFFNPAE
HHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
GGDVLLWQHLFWFFGHPEVYIIFLPAVGMVSSIVATFTQRPVFGYLAMVMALIATGVLAF
CCCCHHHHHHHHHHCCCCEEEEEECHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHH
GLWVHHMFVAGLPRLGESFFTASSMAIAVPAGLQIFCWLATIWAGRPIFKTPFLFVIGFI
HHHHHHHHHHCCHHHHHHHHHHCCCEEEECCCHHHHHHHHHHHCCCCCCCCHHHHHHHHH
VVFVIGGLTGVMVASVPFDTQVHDTYFVVAHFHYVLVGGAVFPLLGAIYYWFPKLTGRMM
HHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SETLGRWSFGLIFSGFNLTFFPMHILGLQGMPRRIYTYQPEMPWSGLNMFISLSGIVLAA
HHHHCCCCHHHEEECCCHHHHHHHHHCCCCCCCCEEEECCCCCCCHHHHHHHHHHHHHHH
GFLLFFIDAIRSARSGPIAPANPWGASTLEWATSSPPPSYNFARLPVVESLEPLSDRSDP
HHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEECCHHHHCCCCCCCCCC
LGTVEGLHTDRRELLITSVVEARAEARESSVGNSIWPLLAALATSAMLIWSIFTPWAVVW
CCHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
GSIPIAVALIGWFWPKGDPEDES
CCHHHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure
MEAGELDRRLAATWSTPPGLWGALSTVDHKIIGRRYTVTAFVFLALGGVLALLMRLQLAQ
CCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCC
PEARFIGPDRYNQIFTMHGSNMMFLFAVPVMQAMAIYLVPLMVGTRHIAFPRLNAFSYWM
CCHHCCCCCHHCEEEEEECCCEEEHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHH
YLAGGLLLWIAFAVDTGPDIGWFAYVPLSGPQYAAGKRADIWAQMITFTEVSALAIAVEI
HHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
VVTVFKQRAPGMSLDRIPLFVWSMLVTSFLVILAMPAIMIASTSLILDRLVGTHFFNPAE
HHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
GGDVLLWQHLFWFFGHPEVYIIFLPAVGMVSSIVATFTQRPVFGYLAMVMALIATGVLAF
CCCCHHHHHHHHHHCCCCEEEEEECHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHH
GLWVHHMFVAGLPRLGESFFTASSMAIAVPAGLQIFCWLATIWAGRPIFKTPFLFVIGFI
HHHHHHHHHHCCHHHHHHHHHHCCCEEEECCCHHHHHHHHHHHCCCCCCCCHHHHHHHHH
VVFVIGGLTGVMVASVPFDTQVHDTYFVVAHFHYVLVGGAVFPLLGAIYYWFPKLTGRMM
HHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SETLGRWSFGLIFSGFNLTFFPMHILGLQGMPRRIYTYQPEMPWSGLNMFISLSGIVLAA
HHHHCCCCHHHEEECCCHHHHHHHHHCCCCCCCCEEEECCCCCCCHHHHHHHHHHHHHHH
GFLLFFIDAIRSARSGPIAPANPWGASTLEWATSSPPPSYNFARLPVVESLEPLSDRSDP
HHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEECCHHHHCCCCCCCCCC
LGTVEGLHTDRRELLITSVVEARAEARESSVGNSIWPLLAALATSAMLIWSIFTPWAVVW
CCHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
GSIPIAVALIGWFWPKGDPEDES
CCHHHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1847686; 9384377 [H]