Click here to switch to the map view.

The map label for this gene is phoB [H]

Identifier: 13488464

GI number: 13488464

Start: 84457

End: 85155

Strand: Reverse

Name: phoB [H]

Synonym: mll9617

Alternate gene names: 13488464

Gene position: 85155-84457 (Counterclockwise)

Preceding gene: 13488465

Following gene: 13488460

Centisome position: 40.88

GC content: 61.66

Gene sequence:

>699_bases
ATGAAGCCGCTGGTCCTGATCGCCTCGAAGGACCCGGATTTTTTCCTGGTCTTCGGGCACATACTGTCGGTAGCCGGCTT
CGAAACGCAGCTGATCACGGGAGACCGGGAAATCGCACGTGCCATCGCTGCGACAGCCCCGCTTGCCATAATCATGGACT
GCCGTCCGGGCGACCGTGCAATCGTCAAGCAGTGCAGCTGGTTGAAGTCCACCGCCGCAACCAAAGCCACACCGGTCGCG
GGACTGGTTGCCCCGCGCTCCGGCAGGCTGCATCTGGATTTGATCAAGGCTGGCGTCGACGAAATATTTTCCCGGCCGTT
CGCCCCCGAGCAGTTGCTGACATGGCTGCACGGCAAAGCAGGCCTCGCCAAGCTTTCACGCGAGACGGACTCGGGCGAGC
TGGTGCAAGGCGATTTTCGGCTGGAGCGACAGACCCACCGAACATTTTTCAGGCAAAACGAGATCGTGATGCCACCGATC
GAATTCAAGCTTCTGCGCAGCCTTTTGGCGCAGCCTGGCAAGGTCTTCAGCCGCGAGGAACTGGTCGCGACGGCATGGCC
TGAACATGCCGCCGCAACCGACGTGAGGGGCGTCGACGTCCATATAGCCAGGTTACGCAAAAGGCTTCGGGCATCCGTGG
GCAGCGATGTGATCCGGACCGTCCGCTCGGCAGGCTACGCCTTCGCGCCGGAGTGGTAA

Upstream 100 bases:

>100_bases
GCGGGAACCTCGCCGGGCGTCGATCGTCAGGGTGTATTGTCATCGCGCCCATTTGCGCGGTAGTCAGCCCTATGATGTGT
CGAAATCGGTTGATGGACTC

Downstream 100 bases:

>100_bases
CCTGCCGAGCGTGCAGCGTTGCCGGCGCGCCGGTCTGCACCCATCGCTCCTCAATGGCTCAGGATGGTGTCCAGGAACAG
CCGCGCCCGTGGGTGAGCGG

Product: transcriptional regulatory protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 232; Mature: 232

Protein sequence:

>232_residues
MKPLVLIASKDPDFFLVFGHILSVAGFETQLITGDREIARAIAATAPLAIIMDCRPGDRAIVKQCSWLKSTAATKATPVA
GLVAPRSGRLHLDLIKAGVDEIFSRPFAPEQLLTWLHGKAGLAKLSRETDSGELVQGDFRLERQTHRTFFRQNEIVMPPI
EFKLLRSLLAQPGKVFSREELVATAWPEHAAATDVRGVDVHIARLRKRLRASVGSDVIRTVRSAGYAFAPEW

Sequences:

>Translated_232_residues
MKPLVLIASKDPDFFLVFGHILSVAGFETQLITGDREIARAIAATAPLAIIMDCRPGDRAIVKQCSWLKSTAATKATPVA
GLVAPRSGRLHLDLIKAGVDEIFSRPFAPEQLLTWLHGKAGLAKLSRETDSGELVQGDFRLERQTHRTFFRQNEIVMPPI
EFKLLRSLLAQPGKVFSREELVATAWPEHAAATDVRGVDVHIARLRKRLRASVGSDVIRTVRSAGYAFAPEW
>Mature_232_residues
MKPLVLIASKDPDFFLVFGHILSVAGFETQLITGDREIARAIAATAPLAIIMDCRPGDRAIVKQCSWLKSTAATKATPVA
GLVAPRSGRLHLDLIKAGVDEIFSRPFAPEQLLTWLHGKAGLAKLSRETDSGELVQGDFRLERQTHRTFFRQNEIVMPPI
EFKLLRSLLAQPGKVFSREELVATAWPEHAAATDVRGVDVHIARLRKRLRASVGSDVIRTVRSAGYAFAPEW

Specific function: This protein is a positive regulator for the phosphate regulon. Transcription of this operon is positively regulated by phoB and phoR when phosphate is limited [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1786599, Length=184, Percent_Identity=30.9782608695652, Blast_Score=83, Evalue=2e-17,
Organism=Escherichia coli, GI1788394, Length=226, Percent_Identity=24.3362831858407, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1790860, Length=212, Percent_Identity=26.8867924528302, Blast_Score=65, Evalue=5e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR016032
- InterPro:   IPR011879
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 25600; Mature: 25600

Theoretical pI: Translated: 10.41; Mature: 10.41

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKPLVLIASKDPDFFLVFGHILSVAGFETQLITGDREIARAIAATAPLAIIMDCRPGDRA
CCCEEEEECCCCCEEEHHHHHHHHCCCCEEEEECCHHHHHHHHHHCCEEEEEECCCCCHH
IVKQCSWLKSTAATKATPVAGLVAPRSGRLHLDLIKAGVDEIFSRPFAPEQLLTWLHGKA
HHHHHHHHHHHHCCCCCCCCEEECCCCCCEEHHHHHHHHHHHHCCCCCHHHHHHHHCCCH
GLAKLSRETDSGELVQGDFRLERQTHRTFFRQNEIVMPPIEFKLLRSLLAQPGKVFSREE
HHHHHHCCCCCCCEEECHHHHHHHHHHHHHHCCCEEECCHHHHHHHHHHCCCCCCCCHHH
LVATAWPEHAAATDVRGVDVHIARLRKRLRASVGSDVIRTVRSAGYAFAPEW
HHHHCCCCHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure
MKPLVLIASKDPDFFLVFGHILSVAGFETQLITGDREIARAIAATAPLAIIMDCRPGDRA
CCCEEEEECCCCCEEEHHHHHHHHCCCCEEEEECCHHHHHHHHHHCCEEEEEECCCCCHH
IVKQCSWLKSTAATKATPVAGLVAPRSGRLHLDLIKAGVDEIFSRPFAPEQLLTWLHGKA
HHHHHHHHHHHHCCCCCCCCEEECCCCCCEEHHHHHHHHHHHHCCCCCHHHHHHHHCCCH
GLAKLSRETDSGELVQGDFRLERQTHRTFFRQNEIVMPPIEFKLLRSLLAQPGKVFSREE
HHHHHHCCCCCCCEEECHHHHHHHHHHHHHHCCCEEECCHHHHHHHHHHCCCCCCCCHHH
LVATAWPEHAAATDVRGVDVHIARLRKRLRASVGSDVIRTVRSAGYAFAPEW
HHHHCCCCHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11481430 [H]