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The map label for this gene is cspA [C]

Identifier: 13488430

GI number: 13488430

Start: 50969

End: 51178

Strand: Reverse

Name: cspA [C]

Synonym: msl9578

Alternate gene names: 13488430

Gene position: 51178-50969 (Counterclockwise)

Preceding gene: 13488433

Following gene: 13488429

Centisome position: 24.57

GC content: 56.67

Gene sequence:

>210_bases
ATGACCACTGGCACAGTTAAATGGTTCAATTCCACCAAGGGCTTCGGCTTCATTCAGCCTGACAGCGGCGGCGCTGACGC
TTTCGTTCACATCTCTGCCGTCGAACGCGCCGGAATGCGCGAAATCGTCGAGGGTCAGAAGATCGGCTATGAGATGGAGC
GCGACAGCAAGTCAGGCAAAATGTCTGCCTGCAACCTGCAGGCCGTCTGA

Upstream 100 bases:

>100_bases
CCGCGCCCTGAACGAACCTTCCCTTCAAAATCGTCATCGTCACAAATCGGGAGCGCACTCGCGTTGCCGTCGTCCAATAT
TGCTATGAAAAGGGTTCATC

Downstream 100 bases:

>100_bases
TCGGTCCAGCTTTCCTTTGATCACGGATGTACTGGCACTGTTGAAAGCGTGAGACCAAGCGAGGTCAGGCAAAATTGGCT
GACCTTTTTATGTCCGGCCG

Product: cold shock protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 69; Mature: 68

Protein sequence:

>69_residues
MTTGTVKWFNSTKGFGFIQPDSGGADAFVHISAVERAGMREIVEGQKIGYEMERDSKSGKMSACNLQAV

Sequences:

>Translated_69_residues
MTTGTVKWFNSTKGFGFIQPDSGGADAFVHISAVERAGMREIVEGQKIGYEMERDSKSGKMSACNLQAV
>Mature_68_residues
TTGTVKWFNSTKGFGFIQPDSGGADAFVHISAVERAGMREIVEGQKIGYEMERDSKSGKMSACNLQAV

Specific function: Binds To And Stimulates The Transcription Of The CCAAT- Containing, Cold-Shock-Inducible Promoters Of The H-Ns And Gyra Proteins. Binds Also To The Inverted Repeat 5'-ATTGG-3'. [C]

COG id: COG1278

COG function: function code K; Cold shock proteins

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 CSD (cold-shock) domain [H]

Homologues:

Organism=Escherichia coli, GI1789979, Length=55, Percent_Identity=52.7272727272727, Blast_Score=69, Evalue=6e-14,
Organism=Escherichia coli, GI1786841, Length=66, Percent_Identity=45.4545454545455, Blast_Score=67, Evalue=3e-13,
Organism=Escherichia coli, GI1787839, Length=55, Percent_Identity=50.9090909090909, Blast_Score=66, Evalue=6e-13,
Organism=Escherichia coli, GI2367114, Length=52, Percent_Identity=50, Blast_Score=64, Evalue=2e-12,
Organism=Escherichia coli, GI1788126, Length=66, Percent_Identity=45.4545454545455, Blast_Score=64, Evalue=2e-12,
Organism=Escherichia coli, GI1787107, Length=62, Percent_Identity=43.5483870967742, Blast_Score=62, Evalue=1e-11,
Organism=Escherichia coli, GI1787834, Length=55, Percent_Identity=45.4545454545455, Blast_Score=59, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR019844
- InterPro:   IPR012156
- InterPro:   IPR011129
- InterPro:   IPR002059
- InterPro:   IPR012340
- InterPro:   IPR016027 [H]

Pfam domain/function: PF00313 CSD [H]

EC number: NA

Molecular weight: Translated: 7460; Mature: 7328

Theoretical pI: Translated: 7.36; Mature: 7.36

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
5.8 %Met     (Translated Protein)
7.2 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
4.4 %Met     (Mature Protein)
5.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTGTVKWFNSTKGFGFIQPDSGGADAFVHISAVERAGMREIVEGQKIGYEMERDSKSGK
CCCCEEEECCCCCCCEEECCCCCCCCEEEEEEHHHCCCHHHHHCCCCCCEEECCCCCCCC
MSACNLQAV
EEEEEEECC
>Mature Secondary Structure 
TTGTVKWFNSTKGFGFIQPDSGGADAFVHISAVERAGMREIVEGQKIGYEMERDSKSGK
CCCEEEECCCCCCCEEECCCCCCCCEEEEEEHHHCCCHHHHHCCCCCCEEECCCCCCCC
MSACNLQAV
EEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9163424 [H]