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The map label for this gene is aceE [H]

Identifier: 13488399

GI number: 13488399

Start: 24761

End: 27139

Strand: Direct

Name: aceE [H]

Synonym: mlr9539

Alternate gene names: 13488399

Gene position: 24761-27139 (Clockwise)

Preceding gene: 13488397

Following gene: 13488400

Centisome position: 11.89

GC content: 63.85

Gene sequence:

>2379_bases
ATGACGATCCTTTCCGAGCTTGAGCGCAAGGTGCTTTGGTTGGCTGTCTGGATGATCCATCATGCCAATCATGTTCGCGG
GTCCGATGATGGCCTCAAGATCGGCGGCCATCAGGCGTCGTCGGCGTCCGCCTCGACCTTGCTGACGGCGCTCTATTTCC
AAATCCTCAGGCCTGAAGACCGGGTGGCCGTCAAGCCGCATGCCAGCCCGGTTTTTCACGCCATCCAGTATCTGTTCGGC
AAGCAGACGCTCGAGCAGCTGCAAAATTTTCGCGGCTATCGCGGCGCGCAGTCCTACCCATCCCGAACCAAGGATATCGA
CGATGTCGATTTCTCGACCGGGTCGGTTGGACTGGGGGTGGCGCAGACCCTCTTCTCGTCCCTCGTCCAGGATTATGTCA
GGGCAAAAGGCTGGAACGCGGACAAGCCCGACGGCCGGATGGTCGCCCTTCTCGGCGACGCTGAAATGGATGAGGGCAAT
ATCTTCGAGGCCCTTCTCGAAGGCTGGAAACACGGCCTGCGCAACACCTGGTGGGTCGTCGACTACAACAGGCAGAGCCT
GGATGCGGTGGTGCGCGAAGGCCTGTGGCAGCGCTTCGAGTCCATCTTTCGCAACTTCGGCTGGGATGTGGTGATCCTGA
AACATGGGACAATGCAAAAGGCGGCCTTTGAGGAGGAGGGCGGTGAAAAGCTGCGGTCCTGGATCGATGCATGCCCCAAC
CAGCTCTATTCGGCGCTGACCTTCCAGGGCGGCGCCGCGTGGCGCCGGCGCCTTCTGGATGACCTGGGGGACCAAGGACC
GGTGACCCGCCTGATCGAGAAGCGAAGCGACGACGACCTTGCCGCCTTGATGGCAAACCTTGGCGGCCACGATCTGGCAA
GCATCATCGATGCCTTCGAGCAAGCGCGCGGTCATGATCGTCCGACCTGTTTCATCGCCTATACGATCAAGGGCTTCGGC
CTGCCGCTCGCCGGCCACAAAGACAATCACGCCGGATTGATGACGCCGGCGCAGGTCGACGCGCTGCGGCAAGGCATGGG
TGTGCGCGAGGGGCGTGAATGGGACCTGTTCGAGGGCCTTGCATACGATGAGGCCGCGATCCGGTCCTATCTGGCGTCGT
CGCCTTTCGCGCAGGCAGCTACCCGTCGCCATAAAACTCCAGCCGTACCCGTGCCGCAGATCCCCTGGGGCGCACAGGCC
TCCATGTCGACACAACAGGGCTTCGGTCTCTTGATGCACGAGATCGCCAAGTCAGACAGCGATTTTTCCAAGCGTGTCGT
GACCACGTCTCCGGACGTCACGGTCTCGACCAATCTCGGGGCCTGGGTGAACAGGCGGGGCCTGTTCGCGCGCGGCGGAC
AGGCAGACCTCTTCCGGGAAGAGCGCATTCCCTCTACCTTCAACTGGACATTTTCGCCGTCGGGACAGCATCTCGAACTG
GGCATCTCGGAGATGAACCTCTTCACGATGCTGTCGGCGCTGGGTCTGTCGCACACGCTTCACGGCGAGCGCCTGCTTCC
GGTAGGAACGCTCTACGACCCCTTCATCGAGCGTGGTCTCGATGCGCTCAACTATGCTTGCTATCAGGATGCACGCTTTA
TCCTGGCGGCGACGCCATCAGGCGTGACACTGGCGCCCGAGGGAGGAGCGCATCAGTCGATCGCCACGCCGCTGATCGGC
ATGGCGCAAGACGGCCTGGCGGCGTTCGAGCCGGCCTATGTCGACGAGCTGGCAGTCATCCTGCGTTGGGCATTCGACTA
TATCCAGCGCTCCGGCGAGGCCGAGCCCGACAACCACAGCTGGCTGCGCGACCAGACCGGAGGTTCAGTCTACCTCAGGC
TCTCCACGCGATCGATCGAGCAGCCGGCACGCCAGATGGAGGATCCGCTGGCGCGCGCCATCGTCGATGGCGCCTACTGG
CTGCGCAAACCCGGGCCGAATGCCGCTGTGGTGATCGCCTATTCGGGAGCTGTCGCGCCGGAAGCTGTCCAGGCATTGGG
GCTGATGGCGGGTGACCGGCGCGATGTCGGGCTTCTGGCCGTGACCTCGGCCGATCGGCTGAACGCCGGCTGGTCTGCCG
CGGCGCGGGCGCGCCAGTATGGCCATCCCCGCGCCACCAGCCATGTCGAGCGCCTGCTGGCTGGTCTGCCCGCCTCATGC
GCCATCGTGACGGTGCTGGACGGGCATCCCGCGACGCTCGCCTGGCTGGGTTCGGTCCATGGCCATCGCACGCGCGCGCT
CGGCGTCGAGCATTTTGGCCAGACCGGTACGATCGCGGACCTCTACCAGTATTACGGGATCGATGCGCAAGGCATCATGG
CTGCGGCGCAATCGGTGTCAGTCGGCCGGCCGCTGAGGCACCTCGGCTCCGCCGCCTGA

Upstream 100 bases:

>100_bases
TAGCTAGATCAGCCAATCTTGCTGAATGCATCGAGCAAGAATAGCCACATTTCGACGACCGATCTAGCTATCCTCAAGAA
CGATTTTACGGGAGCCGACG

Downstream 100 bases:

>100_bases
CGATCGGCCAGCATCGCCTCGTCCCCTGCTGGTACAACAGGAAGCCGTCAATACCGGAATTCCTTGAGAGAGGCCGTCAG
TCGTCGGCGCCATCTTCCCG

Product: pyruvate dehydrogenase E1 component-like protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 792; Mature: 791

Protein sequence:

>792_residues
MTILSELERKVLWLAVWMIHHANHVRGSDDGLKIGGHQASSASASTLLTALYFQILRPEDRVAVKPHASPVFHAIQYLFG
KQTLEQLQNFRGYRGAQSYPSRTKDIDDVDFSTGSVGLGVAQTLFSSLVQDYVRAKGWNADKPDGRMVALLGDAEMDEGN
IFEALLEGWKHGLRNTWWVVDYNRQSLDAVVREGLWQRFESIFRNFGWDVVILKHGTMQKAAFEEEGGEKLRSWIDACPN
QLYSALTFQGGAAWRRRLLDDLGDQGPVTRLIEKRSDDDLAALMANLGGHDLASIIDAFEQARGHDRPTCFIAYTIKGFG
LPLAGHKDNHAGLMTPAQVDALRQGMGVREGREWDLFEGLAYDEAAIRSYLASSPFAQAATRRHKTPAVPVPQIPWGAQA
SMSTQQGFGLLMHEIAKSDSDFSKRVVTTSPDVTVSTNLGAWVNRRGLFARGGQADLFREERIPSTFNWTFSPSGQHLEL
GISEMNLFTMLSALGLSHTLHGERLLPVGTLYDPFIERGLDALNYACYQDARFILAATPSGVTLAPEGGAHQSIATPLIG
MAQDGLAAFEPAYVDELAVILRWAFDYIQRSGEAEPDNHSWLRDQTGGSVYLRLSTRSIEQPARQMEDPLARAIVDGAYW
LRKPGPNAAVVIAYSGAVAPEAVQALGLMAGDRRDVGLLAVTSADRLNAGWSAAARARQYGHPRATSHVERLLAGLPASC
AIVTVLDGHPATLAWLGSVHGHRTRALGVEHFGQTGTIADLYQYYGIDAQGIMAAAQSVSVGRPLRHLGSAA

Sequences:

>Translated_792_residues
MTILSELERKVLWLAVWMIHHANHVRGSDDGLKIGGHQASSASASTLLTALYFQILRPEDRVAVKPHASPVFHAIQYLFG
KQTLEQLQNFRGYRGAQSYPSRTKDIDDVDFSTGSVGLGVAQTLFSSLVQDYVRAKGWNADKPDGRMVALLGDAEMDEGN
IFEALLEGWKHGLRNTWWVVDYNRQSLDAVVREGLWQRFESIFRNFGWDVVILKHGTMQKAAFEEEGGEKLRSWIDACPN
QLYSALTFQGGAAWRRRLLDDLGDQGPVTRLIEKRSDDDLAALMANLGGHDLASIIDAFEQARGHDRPTCFIAYTIKGFG
LPLAGHKDNHAGLMTPAQVDALRQGMGVREGREWDLFEGLAYDEAAIRSYLASSPFAQAATRRHKTPAVPVPQIPWGAQA
SMSTQQGFGLLMHEIAKSDSDFSKRVVTTSPDVTVSTNLGAWVNRRGLFARGGQADLFREERIPSTFNWTFSPSGQHLEL
GISEMNLFTMLSALGLSHTLHGERLLPVGTLYDPFIERGLDALNYACYQDARFILAATPSGVTLAPEGGAHQSIATPLIG
MAQDGLAAFEPAYVDELAVILRWAFDYIQRSGEAEPDNHSWLRDQTGGSVYLRLSTRSIEQPARQMEDPLARAIVDGAYW
LRKPGPNAAVVIAYSGAVAPEAVQALGLMAGDRRDVGLLAVTSADRLNAGWSAAARARQYGHPRATSHVERLLAGLPASC
AIVTVLDGHPATLAWLGSVHGHRTRALGVEHFGQTGTIADLYQYYGIDAQGIMAAAQSVSVGRPLRHLGSAA
>Mature_791_residues
TILSELERKVLWLAVWMIHHANHVRGSDDGLKIGGHQASSASASTLLTALYFQILRPEDRVAVKPHASPVFHAIQYLFGK
QTLEQLQNFRGYRGAQSYPSRTKDIDDVDFSTGSVGLGVAQTLFSSLVQDYVRAKGWNADKPDGRMVALLGDAEMDEGNI
FEALLEGWKHGLRNTWWVVDYNRQSLDAVVREGLWQRFESIFRNFGWDVVILKHGTMQKAAFEEEGGEKLRSWIDACPNQ
LYSALTFQGGAAWRRRLLDDLGDQGPVTRLIEKRSDDDLAALMANLGGHDLASIIDAFEQARGHDRPTCFIAYTIKGFGL
PLAGHKDNHAGLMTPAQVDALRQGMGVREGREWDLFEGLAYDEAAIRSYLASSPFAQAATRRHKTPAVPVPQIPWGAQAS
MSTQQGFGLLMHEIAKSDSDFSKRVVTTSPDVTVSTNLGAWVNRRGLFARGGQADLFREERIPSTFNWTFSPSGQHLELG
ISEMNLFTMLSALGLSHTLHGERLLPVGTLYDPFIERGLDALNYACYQDARFILAATPSGVTLAPEGGAHQSIATPLIGM
AQDGLAAFEPAYVDELAVILRWAFDYIQRSGEAEPDNHSWLRDQTGGSVYLRLSTRSIEQPARQMEDPLARAIVDGAYWL
RKPGPNAAVVIAYSGAVAPEAVQALGLMAGDRRDVGLLAVTSADRLNAGWSAAARARQYGHPRATSHVERLLAGLPASCA
IVTVLDGHPATLAWLGSVHGHRTRALGVEHFGQTGTIADLYQYYGIDAQGIMAAAQSVSVGRPLRHLGSAA

Specific function: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components:pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydroge

COG id: COG2609

COG function: function code C; Pyruvate dehydrogenase complex, dehydrogenase (E1) component

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1786304, Length=818, Percent_Identity=23.960880195599, Blast_Score=141, Evalue=2e-34,

Paralogues:

None

Copy number: 1140 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). 400 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). 6,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004660
- InterPro:   IPR009014
- InterPro:   IPR015941
- InterPro:   IPR005474 [H]

Pfam domain/function: PF00456 Transketolase_N [H]

EC number: =1.2.4.1 [H]

Molecular weight: Translated: 86600; Mature: 86469

Theoretical pI: Translated: 6.58; Mature: 6.58

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTILSELERKVLWLAVWMIHHANHVRGSDDGLKIGGHQASSASASTLLTALYFQILRPED
CCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEECCCCCCCHHHHHHHHHHHHHHHCCCC
RVAVKPHASPVFHAIQYLFGKQTLEQLQNFRGYRGAQSYPSRTKDIDDVDFSTGSVGLGV
CEEECCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCHHHH
AQTLFSSLVQDYVRAKGWNADKPDGRMVALLGDAEMDEGNIFEALLEGWKHGLRNTWWVV
HHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHCCCCEEEEE
DYNRQSLDAVVREGLWQRFESIFRNFGWDVVILKHGTMQKAAFEEEGGEKLRSWIDACPN
ECCHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHH
QLYSALTFQGGAAWRRRLLDDLGDQGPVTRLIEKRSDDDLAALMANLGGHDLASIIDAFE
HHHHHHHCCCCHHHHHHHHHHCCCCCHHHHHHHCCCCCHHHHHHHHCCCHHHHHHHHHHH
QARGHDRPTCFIAYTIKGFGLPLAGHKDNHAGLMTPAQVDALRQGMGVREGREWDLFEGL
HHCCCCCCEEEEEEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCHHHCC
AYDEAAIRSYLASSPFAQAATRRHKTPAVPVPQIPWGAQASMSTQQGFGLLMHEIAKSDS
CHHHHHHHHHHHCCCHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCC
DFSKRVVTTSPDVTVSTNLGAWVNRRGLFARGGQADLFREERIPSTFNWTFSPSGQHLEL
CHHCEEEECCCCEEEECCCCCHHCCCCCEECCCCHHHHHHHCCCCCEEEEECCCCCEEEE
GISEMNLFTMLSALGLSHTLHGERLLPVGTLYDPFIERGLDALNYACYQDARFILAATPS
CHHHHHHHHHHHHHHCHHCCCCCCCCCCHHHHHHHHHHCHHHHHHHHHHCCEEEEEECCC
GVTLAPEGGAHQSIATPLIGMAQDGLAAFEPAYVDELAVILRWAFDYIQRSGEAEPDNHS
CCEECCCCCCCHHHHHHHHHHCCCCHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
WLRDQTGGSVYLRLSTRSIEQPARQMEDPLARAIVDGAYWLRKPGPNAAVVIAYSGAVAP
CHHCCCCCEEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCH
EAVQALGLMAGDRRDVGLLAVTSADRLNAGWSAAARARQYGHPRATSHVERLLAGLPASC
HHHHHHHHHCCCCCCCEEEEEECCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHCCCCCE
AIVTVLDGHPATLAWLGSVHGHRTRALGVEHFGQTGTIADLYQYYGIDAQGIMAAAQSVS
EEEEEECCCCCHHHHHHCCCCCHHHHHHHHHCCCCCCHHHHHHHHCCCHHHHHHHHHHHH
VGRPLRHLGSAA
CCCHHHHHCCCC
>Mature Secondary Structure 
TILSELERKVLWLAVWMIHHANHVRGSDDGLKIGGHQASSASASTLLTALYFQILRPED
CCHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEECCCCCCCHHHHHHHHHHHHHHHCCCC
RVAVKPHASPVFHAIQYLFGKQTLEQLQNFRGYRGAQSYPSRTKDIDDVDFSTGSVGLGV
CEEECCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCHHHH
AQTLFSSLVQDYVRAKGWNADKPDGRMVALLGDAEMDEGNIFEALLEGWKHGLRNTWWVV
HHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHCCCCEEEEE
DYNRQSLDAVVREGLWQRFESIFRNFGWDVVILKHGTMQKAAFEEEGGEKLRSWIDACPN
ECCHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHH
QLYSALTFQGGAAWRRRLLDDLGDQGPVTRLIEKRSDDDLAALMANLGGHDLASIIDAFE
HHHHHHHCCCCHHHHHHHHHHCCCCCHHHHHHHCCCCCHHHHHHHHCCCHHHHHHHHHHH
QARGHDRPTCFIAYTIKGFGLPLAGHKDNHAGLMTPAQVDALRQGMGVREGREWDLFEGL
HHCCCCCCEEEEEEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCHHHCC
AYDEAAIRSYLASSPFAQAATRRHKTPAVPVPQIPWGAQASMSTQQGFGLLMHEIAKSDS
CHHHHHHHHHHHCCCHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCC
DFSKRVVTTSPDVTVSTNLGAWVNRRGLFARGGQADLFREERIPSTFNWTFSPSGQHLEL
CHHCEEEECCCCEEEECCCCCHHCCCCCEECCCCHHHHHHHCCCCCEEEEECCCCCEEEE
GISEMNLFTMLSALGLSHTLHGERLLPVGTLYDPFIERGLDALNYACYQDARFILAATPS
CHHHHHHHHHHHHHHCHHCCCCCCCCCCHHHHHHHHHHCHHHHHHHHHHCCEEEEEECCC
GVTLAPEGGAHQSIATPLIGMAQDGLAAFEPAYVDELAVILRWAFDYIQRSGEAEPDNHS
CCEECCCCCCCHHHHHHHHHHCCCCHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
WLRDQTGGSVYLRLSTRSIEQPARQMEDPLARAIVDGAYWLRKPGPNAAVVIAYSGAVAP
CHHCCCCCEEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCH
EAVQALGLMAGDRRDVGLLAVTSADRLNAGWSAAARARQYGHPRATSHVERLLAGLPASC
HHHHHHHHHCCCCCCCEEEEEECCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHCCCCCE
AIVTVLDGHPATLAWLGSVHGHRTRALGVEHFGQTGTIADLYQYYGIDAQGIMAAAQSVS
EEEEEECCCCCHHHHHHCCCCCHHHHHHHHHCCCCCCHHHHHHHHCCCHHHHHHHHHHHH
VGRPLRHLGSAA
CCCHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA