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The map label for this gene is cheB

Identifier: 13488378

GI number: 13488378

Start: 5889

End: 6908

Strand: Reverse

Name: cheB

Synonym: mll9510

Alternate gene names: 13488378

Gene position: 6908-5889 (Counterclockwise)

Preceding gene: 13488379

Following gene: 13488377

Centisome position: 3.32

GC content: 59.31

Gene sequence:

>1020_bases
ATGAGAATCGGCGTAGTCAACGACATGCCGATGGCGGTTGAACTTTTGCGCCGACTGGTCCTGTCGACCGGCGAACATCA
GGTCGCATGGATCGCGACCAATGGGCGTGAGGCGGTCGAGGTCTGCAGACGTGATCTGCCGGATCTGATACTCATGGATC
TAGCGATGCCAGTGATGGACGGCGTGGAAGCGACCCGCAGAATCATGGCGGAAACCCCGTGCTCAATCTTGCTGGTGACC
GCCAGTATCGAATCCAACCTCGCGGACGTCTACGAAGCAATGGGTCATGGCGCGCTTGACGCAGTCGATATTCCGTCAGT
GGGCATTGAAGGTAACGCGTCCTCGCAATCCGCCCGGCTTTTGACGAACAAGATAGCAACGATCGGCAAGCTGATCGGTG
ATGCGCCGACCAAGGCAAAAAGGCGGATGTCACGTGCGGCTGAGCCGACACCTCGACGCCTGATCGCAATCGGTGCCTCC
GCGGGCGGGCCGGCTGCCGTTGCCGCAGTCCTGAGCGCGTTTCCCGTTGATTTTGGCGGCGCGATCGTGCTCGTCCAGCA
TCTCGATGCTCAGTTCGTTCCAGGCCTTGTTGATTGGCTGGGACAGCATACGCCTCTCCCGATCCGTCCGGCGCGGGAAA
GGGATAGTCCTCAAGCGGGCACCGTTCTCGTTGCCAGTTCTGCGGATCATCTGGTTTTCAAGTCAGTTCAGCAACTTGGC
TATACGCCCAGCCCCAAGGACAATGTTTATCGGCCGTCCGTAGATGTGTTTTTCGAAAGTGCGGCGCAATGGTGGCCTGG
CTCGGTGATTGGTGTTCTGCTCACAGGAATGGGCAGGGATGGTGCGCGCGGGCTGAGACAGCTCCGCGACAAGGGGCATC
TCACAATCGCGCAGGATAGAGCAACCAGTGCCGTCTATGGCATGCCGAAGGCCGCCGCCGACATCGGCGCGGCTGTTGAT
ATTCTTCCTTTGAGTGCGATCGGCTCACGTATTATCGAAGCCTGCGAGCGCTCCACATGA

Upstream 100 bases:

>100_bases
TATCTGACCAAGAGTAGCTTTCAGGACGAGGCGCTGATCCATGCCGTCGTGGACATGATTGGCGAGGCGGCTGAGTGAGA
TCGAAATCGGAAGCCAGCGA

Downstream 100 bases:

>100_bases
AAGGGCTCGTCCGATGACGCAAGAACCAGAGCTGGTCCCGCCACTCGCAGATAACTATTCATCCATGGTTCTGCTCATCG
ATGATCAGATCATGGTTTGC

Product: chemotaxis-specific methylesterase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 339; Mature: 339

Protein sequence:

>339_residues
MRIGVVNDMPMAVELLRRLVLSTGEHQVAWIATNGREAVEVCRRDLPDLILMDLAMPVMDGVEATRRIMAETPCSILLVT
ASIESNLADVYEAMGHGALDAVDIPSVGIEGNASSQSARLLTNKIATIGKLIGDAPTKAKRRMSRAAEPTPRRLIAIGAS
AGGPAAVAAVLSAFPVDFGGAIVLVQHLDAQFVPGLVDWLGQHTPLPIRPARERDSPQAGTVLVASSADHLVFKSVQQLG
YTPSPKDNVYRPSVDVFFESAAQWWPGSVIGVLLTGMGRDGARGLRQLRDKGHLTIAQDRATSAVYGMPKAAADIGAAVD
ILPLSAIGSRIIEACERST

Sequences:

>Translated_339_residues
MRIGVVNDMPMAVELLRRLVLSTGEHQVAWIATNGREAVEVCRRDLPDLILMDLAMPVMDGVEATRRIMAETPCSILLVT
ASIESNLADVYEAMGHGALDAVDIPSVGIEGNASSQSARLLTNKIATIGKLIGDAPTKAKRRMSRAAEPTPRRLIAIGAS
AGGPAAVAAVLSAFPVDFGGAIVLVQHLDAQFVPGLVDWLGQHTPLPIRPARERDSPQAGTVLVASSADHLVFKSVQQLG
YTPSPKDNVYRPSVDVFFESAAQWWPGSVIGVLLTGMGRDGARGLRQLRDKGHLTIAQDRATSAVYGMPKAAADIGAAVD
ILPLSAIGSRIIEACERST
>Mature_339_residues
MRIGVVNDMPMAVELLRRLVLSTGEHQVAWIATNGREAVEVCRRDLPDLILMDLAMPVMDGVEATRRIMAETPCSILLVT
ASIESNLADVYEAMGHGALDAVDIPSVGIEGNASSQSARLLTNKIATIGKLIGDAPTKAKRRMSRAAEPTPRRLIAIGAS
AGGPAAVAAVLSAFPVDFGGAIVLVQHLDAQFVPGLVDWLGQHTPLPIRPARERDSPQAGTVLVASSADHLVFKSVQQLG
YTPSPKDNVYRPSVDVFFESAAQWWPGSVIGVLLTGMGRDGARGLRQLRDKGHLTIAQDRATSAVYGMPKAAADIGAAVD
ILPLSAIGSRIIEACERST

Specific function: Involved in the modulation of the chemotaxis system; catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR

COG id: COG2201

COG function: function code NT; Chemotaxis response regulator containing a CheY-like receiver domain and a methylesterase domain

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain

Homologues:

Organism=Escherichia coli, GI1788192, Length=338, Percent_Identity=27.5147928994083, Blast_Score=137, Evalue=8e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): CHEB_RHILO (Q98PD1)

Other databases:

- EMBL:   AP003017
- RefSeq:   NP_109385.1
- ProteinModelPortal:   Q98PD1
- SMR:   Q98PD1
- GeneID:   1224357
- GenomeReviews:   AP003017_GR
- KEGG:   mlo:mll9510
- NMPDR:   fig|266835.1.peg.7074
- HOGENOM:   HBG705324
- OMA:   FFESVAR
- ProtClustDB:   PRK12555
- BRENDA:   3.1.1.61
- GO:   GO:0005737
- GO:   GO:0006935
- HAMAP:   MF_00099
- InterPro:   IPR011006
- InterPro:   IPR008248
- InterPro:   IPR000673
- InterPro:   IPR001789
- Gene3D:   G3DSA:3.40.50.180
- PIRSF:   PIRSF000876
- SMART:   SM00448

Pfam domain/function: PF01339 CheB_methylest; PF00072 Response_reg; SSF52738 Chemotax_RR_pGlu_Me-esterase; SSF52172 CheY_like

EC number: =3.1.1.61

Molecular weight: Translated: 35891; Mature: 35891

Theoretical pI: Translated: 6.79; Mature: 6.79

Prosite motif: PS50122 CHEB; PS50110 RESPONSE_REGULATORY

Important sites: ACT_SITE 160-160 ACT_SITE 187-187 ACT_SITE 280-280

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRIGVVNDMPMAVELLRRLVLSTGEHQVAWIATNGREAVEVCRRDLPDLILMDLAMPVMD
CEECCCCCCCHHHHHHHHHHHCCCCCEEEEEEECCHHHHHHHHHCCHHHHHHHHHHHHHH
GVEATRRIMAETPCSILLVTASIESNLADVYEAMGHGALDAVDIPSVGIEGNASSQSARL
HHHHHHHHHHCCCCEEEEEEECHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHH
LTNKIATIGKLIGDAPTKAKRRMSRAAEPTPRRLIAIGASAGGPAAVAAVLSAFPVDFGG
HHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCEEEEEECCCCCHHHHHHHHHHCCCCCCC
AIVLVQHLDAQFVPGLVDWLGQHTPLPIRPARERDSPQAGTVLVASSADHLVFKSVQQLG
CEEHEEHHCCHHCCHHHHHHCCCCCCCCCCCCCCCCCCCCEEEEECCCCHHHHHHHHHCC
YTPSPKDNVYRPSVDVFFESAAQWWPGSVIGVLLTGMGRDGARGLRQLRDKGHLTIAQDR
CCCCCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHCCCCHHHHHHHHHHHCCCEEEECCC
ATSAVYGMPKAAADIGAAVDILPLSAIGSRIIEACERST
CCHHHHCCCHHHHHHCCHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MRIGVVNDMPMAVELLRRLVLSTGEHQVAWIATNGREAVEVCRRDLPDLILMDLAMPVMD
CEECCCCCCCHHHHHHHHHHHCCCCCEEEEEEECCHHHHHHHHHCCHHHHHHHHHHHHHH
GVEATRRIMAETPCSILLVTASIESNLADVYEAMGHGALDAVDIPSVGIEGNASSQSARL
HHHHHHHHHHCCCCEEEEEEECHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHH
LTNKIATIGKLIGDAPTKAKRRMSRAAEPTPRRLIAIGASAGGPAAVAAVLSAFPVDFGG
HHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCEEEEEECCCCCHHHHHHHHHHCCCCCCC
AIVLVQHLDAQFVPGLVDWLGQHTPLPIRPARERDSPQAGTVLVASSADHLVFKSVQQLG
CEEHEEHHCCHHCCHHHHHHCCCCCCCCCCCCCCCCCCCCEEEEECCCCHHHHHHHHHCC
YTPSPKDNVYRPSVDVFFESAAQWWPGSVIGVLLTGMGRDGARGLRQLRDKGHLTIAQDR
CCCCCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHCCCCHHHHHHHHHHHCCCEEEECCC
ATSAVYGMPKAAADIGAAVDILPLSAIGSRIIEACERST
CCHHHHCCCHHHHHHCCHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11214968