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The map label for this gene is virB10 [H]

Identifier: 13488268

GI number: 13488268

Start: 236743

End: 237975

Strand: Direct

Name: virB10 [H]

Synonym: mlr9259

Alternate gene names: 13488268

Gene position: 236743-237975 (Clockwise)

Preceding gene: 13488267

Following gene: 13488269

Centisome position: 67.27

GC content: 62.61

Gene sequence:

>1233_bases
ATGATCTATGCGGCGACGCGTGCGCCGGACAAGCCGCTGTTGACGGCGTCGGATGGCGAGGAGTTTCACACCACACAGTT
TCCCGCACCTGGGCTCGATACGCCGCGTCCCCAGCTTGACAACGGCACCCTGAAGATCCCGACGGCTCCCGAGGAGCCGC
CGGCTGCGCCGGCGCAGCCGCCGTCGACGATCGAGGCTCCCCCTCCACCTCCGCCAGCATTGCAACCGCCTGCAGCTCCA
CCGCAGGTTCAGGACGATTCCGAGGCCCGTCGTCTGGCTGAGGAAGAACGGCGCAGGCAGGAAGAAGAGGAGCGCCGCAA
ATGGGAGCGCTTGCGCGCCAAGCAGCTCGTCGTCGATAGCGGCGATGCGCCTGGCAGCGCGTCAGCATTGGGCGGCAATG
GTACGGATGCAGCGGCGGCCGGAAACGCAGGCGAGGGCGAGGAGGACCCCAATCGGCGTTTTTTGGCAAGGGCGAGCCAG
AGCGGAGCGGATACATCGAAGGCCACGATGAACCCGCGCACGGACGCTCTGGTCGCCCAAGGGACGATGATCAAGGGCGT
ACTCGAGACCGCGATCCAGAGCGATCTTGCCGGTATGGTTCGGGCCGTCGTGTCGGAGGATGTGTGGTCGTTCGACGGTC
GCAGGGTTTTGATCCCCGGTGGCTCCCGCCTTATCGGTGAATATCGCAGTGGCCTCGCAACCGGCCAAACGCGGGTGTTC
ATTGTGTGGACACGCCTGCTTCGATCGGACGGCATGTCGGTGCAGCTCGGTTCGACCGGCACCGACGAGCTCGGTCGCAG
CGGCATGCCGGGCGAGGTCGACAACCATTATTTCGAGCGGTTCGGCTCGGCGATCCTTTTAAGTGTCGTGGGTGGCGCGA
CGCAGTTCATCGCCAACCTTGGCACTGATCAGAACGGGTCGAACACCAATCAGACCTATACTGATCCGCAGACCGGACAG
ACGGTGACAATCCAGACGCAACCCAATCAGTACGTGCAGAACGCGCGCCAGATCGGCGCGCAACAGGTCTCACAAAGCCT
CAACCGCATTGCTGAAGAGGCGCTTCGCAATTCGATCAATATCGCGCCGACGATCCATGTCGATCAGGGATCGCGAATAA
TGGTGTTCGTGCGCCGCGACCTCGATTTTTCGGAGTTCTATCCGGACCCGGTACGCGAGGCGTTGACGGAGATACGACGT
GAGCGGGCAGCAAAGAACCGTCTTTCTAAATAA

Upstream 100 bases:

>100_bases
GCTCGCTGAGGAAGGCACGGCGGTCGCCGCGCCAAAATTCGGGGCGAGCACATTCTTCAAGATCGCGGTGCCGCTGGGCG
CGGTGGTCTTCGCCGGCTGG

Downstream 100 bases:

>100_bases
GGCGCTGGAGCCGGTGCGGCGCTGGCTCGACGACGATCGCGTGGTCGAAATCTGCGCAAACGGGCCTGGACTTGTGTGGG
TCGAAATTGTTGGCTCGACA

Product: conjugal transfer protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 410; Mature: 410

Protein sequence:

>410_residues
MIYAATRAPDKPLLTASDGEEFHTTQFPAPGLDTPRPQLDNGTLKIPTAPEEPPAAPAQPPSTIEAPPPPPPALQPPAAP
PQVQDDSEARRLAEEERRRQEEEERRKWERLRAKQLVVDSGDAPGSASALGGNGTDAAAAGNAGEGEEDPNRRFLARASQ
SGADTSKATMNPRTDALVAQGTMIKGVLETAIQSDLAGMVRAVVSEDVWSFDGRRVLIPGGSRLIGEYRSGLATGQTRVF
IVWTRLLRSDGMSVQLGSTGTDELGRSGMPGEVDNHYFERFGSAILLSVVGGATQFIANLGTDQNGSNTNQTYTDPQTGQ
TVTIQTQPNQYVQNARQIGAQQVSQSLNRIAEEALRNSINIAPTIHVDQGSRIMVFVRRDLDFSEFYPDPVREALTEIRR
ERAAKNRLSK

Sequences:

>Translated_410_residues
MIYAATRAPDKPLLTASDGEEFHTTQFPAPGLDTPRPQLDNGTLKIPTAPEEPPAAPAQPPSTIEAPPPPPPALQPPAAP
PQVQDDSEARRLAEEERRRQEEEERRKWERLRAKQLVVDSGDAPGSASALGGNGTDAAAAGNAGEGEEDPNRRFLARASQ
SGADTSKATMNPRTDALVAQGTMIKGVLETAIQSDLAGMVRAVVSEDVWSFDGRRVLIPGGSRLIGEYRSGLATGQTRVF
IVWTRLLRSDGMSVQLGSTGTDELGRSGMPGEVDNHYFERFGSAILLSVVGGATQFIANLGTDQNGSNTNQTYTDPQTGQ
TVTIQTQPNQYVQNARQIGAQQVSQSLNRIAEEALRNSINIAPTIHVDQGSRIMVFVRRDLDFSEFYPDPVREALTEIRR
ERAAKNRLSK
>Mature_410_residues
MIYAATRAPDKPLLTASDGEEFHTTQFPAPGLDTPRPQLDNGTLKIPTAPEEPPAAPAQPPSTIEAPPPPPPALQPPAAP
PQVQDDSEARRLAEEERRRQEEEERRKWERLRAKQLVVDSGDAPGSASALGGNGTDAAAAGNAGEGEEDPNRRFLARASQ
SGADTSKATMNPRTDALVAQGTMIKGVLETAIQSDLAGMVRAVVSEDVWSFDGRRVLIPGGSRLIGEYRSGLATGQTRVF
IVWTRLLRSDGMSVQLGSTGTDELGRSGMPGEVDNHYFERFGSAILLSVVGGATQFIANLGTDQNGSNTNQTYTDPQTGQ
TVTIQTQPNQYVQNARQIGAQQVSQSLNRIAEEALRNSINIAPTIHVDQGSRIMVFVRRDLDFSEFYPDPVREALTEIRR
ERAAKNRLSK

Specific function: Component of the type IV secretion system virB/virD4 which could be a major virulence determinant for subversion of human endothelial cell (HEC) function [H]

COG id: COG2948

COG function: function code U; Type IV secretory pathway, VirB10 components

Gene ontology:

Cell location: Cell inner membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the trbI/virB10 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005498 [H]

Pfam domain/function: PF03743 TrbI [H]

EC number: NA

Molecular weight: Translated: 44328; Mature: 44328

Theoretical pI: Translated: 4.91; Mature: 4.91

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIYAATRAPDKPLLTASDGEEFHTTQFPAPGLDTPRPQLDNGTLKIPTAPEEPPAAPAQP
CEEECCCCCCCCEEECCCCCCCCCCCCCCCCCCCCCCCCCCCEEECCCCCCCCCCCCCCC
PSTIEAPPPPPPALQPPAAPPQVQDDSEARRLAEEERRRQEEEERRKWERLRAKQLVVDS
CCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEC
GDAPGSASALGGNGTDAAAAGNAGEGEEDPNRRFLARASQSGADTSKATMNPRTDALVAQ
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCCCCCCCCCCCCCCHHHHC
GTMIKGVLETAIQSDLAGMVRAVVSEDVWSFDGRRVLIPGGSRLIGEYRSGLATGQTRVF
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCHHHHHHHHCCCCCCCCEEE
IVWTRLLRSDGMSVQLGSTGTDELGRSGMPGEVDNHYFERFGSAILLSVVGGATQFIANL
HHHHHHHHCCCCEEEECCCCCHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHC
GTDQNGSNTNQTYTDPQTGQTVTIQTQPNQYVQNARQIGAQQVSQSLNRIAEEALRNSIN
CCCCCCCCCCCCCCCCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
IAPTIHVDQGSRIMVFVRRDLDFSEFYPDPVREALTEIRRERAAKNRLSK
CCEEEEECCCCEEEEEEECCCCHHHCCCCHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MIYAATRAPDKPLLTASDGEEFHTTQFPAPGLDTPRPQLDNGTLKIPTAPEEPPAAPAQP
CEEECCCCCCCCEEECCCCCCCCCCCCCCCCCCCCCCCCCCCEEECCCCCCCCCCCCCCC
PSTIEAPPPPPPALQPPAAPPQVQDDSEARRLAEEERRRQEEEERRKWERLRAKQLVVDS
CCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEC
GDAPGSASALGGNGTDAAAAGNAGEGEEDPNRRFLARASQSGADTSKATMNPRTDALVAQ
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCCCCCCCCCCCCCCHHHHC
GTMIKGVLETAIQSDLAGMVRAVVSEDVWSFDGRRVLIPGGSRLIGEYRSGLATGQTRVF
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCHHHHHHHHCCCCCCCCEEE
IVWTRLLRSDGMSVQLGSTGTDELGRSGMPGEVDNHYFERFGSAILLSVVGGATQFIANL
HHHHHHHHCCCCEEEECCCCCHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHC
GTDQNGSNTNQTYTDPQTGQTVTIQTQPNQYVQNARQIGAQQVSQSLNRIAEEALRNSIN
CCCCCCCCCCCCCCCCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
IAPTIHVDQGSRIMVFVRRDLDFSEFYPDPVREALTEIRRERAAKNRLSK
CCEEEEECCCCEEEEEEECCCCHHHCCCCHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA