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The map label for this gene is virB9 [H]

Identifier: 13488267

GI number: 13488267

Start: 235797

End: 236633

Strand: Direct

Name: virB9 [H]

Synonym: mlr9258

Alternate gene names: 13488267

Gene position: 235797-236633 (Clockwise)

Preceding gene: 13488266

Following gene: 13488268

Centisome position: 67.0

GC content: 59.02

Gene sequence:

>837_bases
ATGAACGTCGCCGGCATCCTGATGGCAATCGGGCTCGGCGTTTGCGCGGTTCAGCCGGCCCTTGCCGAACAGACTCCTCG
GGCGGGATCTCGTGACAGTCGCATTCGCTTCGTCTGGTATCAGAAGGACGATGTGGTGTCGGTGCCGGCCAGCTATGGCG
CCTCGACCATGATCGAATTCGGCGATGACGAGAAAATCGAAACCCTCGGCGCCGGCGACGTCCCGGCCTGGAGCATCGAG
CCCAACAAGAAGGGCAACGTGCTGTTTGTGAAACCGATCGAGAAGAATGCGGGCGGGAATCTCAACGTCCTGACCAACAA
GCGCAGCTATGTGTTCTTCCTGAAGGGCGAGTTTCGGCCGGTTGCGCAACAGGTCTATGCGATCAAGTTCCGCTATCCCG
AAGAGGCCTCGGACGCGGCGCTGATGGACGAAGCCCGGGCCCGGGCATCACAACCGAACCGGCAGGGCTTCAAGGCCGAA
AATGCCAACTCGTCCTATGCCTATAAGGGTTCGTCGGCAAATAAGCCGCTCGTGATCTACGACGACGGCGTGAAGACCTG
GTTCCGCTTCGATCCGGCAAGGGAAGTGCCGGCGATCTATGTCGTCGACAGCGAGCGCAATGAGACCCTTGTGAATTATC
GCCGCGAGGGCGCGTACATCGTCGTCGACAAGGTCAATTTCCAATGGACCTTGCGCAACGGACACGACGCAACCTGCGTC
TTCAATCTGAGACTGAACAATGTGAACGAACCGACCGGGCTTGAACCTTACCAGCCACAGCGTGTCGGTGGTGGGGTTGT
TCAGAAAGTGAGGGGACCCGATGCCATCTCCCAATGA

Upstream 100 bases:

>100_bases
CTAAAAACGAGATCCGCTTTCAAAATCCGCTCGGCTTCCAGGTGCTCGAATATCGGCGCGATCAGGAGACGGCGCCGGCA
CCCACCGCGGAGACACCGCA

Downstream 100 bases:

>100_bases
GTACAGAATGCTCGCTGAGGAAGGCACGGCGGTCGCCGCGCCAAAATTCGGGGCGAGCACATTCTTCAAGATCGCGGTGC
CGCTGGGCGCGGTGGTCTTC

Product: conjugal transfer protein TrbG

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 278; Mature: 278

Protein sequence:

>278_residues
MNVAGILMAIGLGVCAVQPALAEQTPRAGSRDSRIRFVWYQKDDVVSVPASYGASTMIEFGDDEKIETLGAGDVPAWSIE
PNKKGNVLFVKPIEKNAGGNLNVLTNKRSYVFFLKGEFRPVAQQVYAIKFRYPEEASDAALMDEARARASQPNRQGFKAE
NANSSYAYKGSSANKPLVIYDDGVKTWFRFDPAREVPAIYVVDSERNETLVNYRREGAYIVVDKVNFQWTLRNGHDATCV
FNLRLNNVNEPTGLEPYQPQRVGGGVVQKVRGPDAISQ

Sequences:

>Translated_278_residues
MNVAGILMAIGLGVCAVQPALAEQTPRAGSRDSRIRFVWYQKDDVVSVPASYGASTMIEFGDDEKIETLGAGDVPAWSIE
PNKKGNVLFVKPIEKNAGGNLNVLTNKRSYVFFLKGEFRPVAQQVYAIKFRYPEEASDAALMDEARARASQPNRQGFKAE
NANSSYAYKGSSANKPLVIYDDGVKTWFRFDPAREVPAIYVVDSERNETLVNYRREGAYIVVDKVNFQWTLRNGHDATCV
FNLRLNNVNEPTGLEPYQPQRVGGGVVQKVRGPDAISQ
>Mature_278_residues
MNVAGILMAIGLGVCAVQPALAEQTPRAGSRDSRIRFVWYQKDDVVSVPASYGASTMIEFGDDEKIETLGAGDVPAWSIE
PNKKGNVLFVKPIEKNAGGNLNVLTNKRSYVFFLKGEFRPVAQQVYAIKFRYPEEASDAALMDEARARASQPNRQGFKAE
NANSSYAYKGSSANKPLVIYDDGVKTWFRFDPAREVPAIYVVDSERNETLVNYRREGAYIVVDKVNFQWTLRNGHDATCV
FNLRLNNVNEPTGLEPYQPQRVGGGVVQKVRGPDAISQ

Specific function: Component of the type IV secretion system virB/virD4 which could be a major virulence determinant for subversion of human endothelial cell (HEC) function [H]

COG id: COG3504

COG function: function code U; Type IV secretory pathway, VirB9 components

Gene ontology:

Cell location: Periplasm (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the trbG/virB9 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010258
- InterPro:   IPR014148 [H]

Pfam domain/function: PF03524 CagX [H]

EC number: NA

Molecular weight: Translated: 30818; Mature: 30818

Theoretical pI: Translated: 8.57; Mature: 8.57

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNVAGILMAIGLGVCAVQPALAEQTPRAGSRDSRIRFVWYQKDDVVSVPASYGASTMIEF
CCHHHHHHHHHHHHHHCCCHHHHCCCCCCCCCCEEEEEEEECCCEEECCCCCCCCEEEEE
GDDEKIETLGAGDVPAWSIEPNKKGNVLFVKPIEKNAGGNLNVLTNKRSYVFFLKGEFRP
CCCCCEEEECCCCCCEEEECCCCCCCEEEEEECCCCCCCCEEEEECCCEEEEEEECCCCH
VAQQVYAIKFRYPEEASDAALMDEARARASQPNRQGFKAENANSSYAYKGSSANKPLVIY
HHEEEEEEEEECCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCEEECCCCCCCCEEEE
DDGVKTWFRFDPAREVPAIYVVDSERNETLVNYRREGAYIVVDKVNFQWTLRNGHDATCV
ECCCCEEEEECCCCCCCEEEEEECCCCCEEEEEECCCCEEEEEECEEEEEEECCCCEEEE
FNLRLNNVNEPTGLEPYQPQRVGGGVVQKVRGPDAISQ
EEEEECCCCCCCCCCCCCCCCCCCHHHHCCCCCCCCCC
>Mature Secondary Structure
MNVAGILMAIGLGVCAVQPALAEQTPRAGSRDSRIRFVWYQKDDVVSVPASYGASTMIEF
CCHHHHHHHHHHHHHHCCCHHHHCCCCCCCCCCEEEEEEEECCCEEECCCCCCCCEEEEE
GDDEKIETLGAGDVPAWSIEPNKKGNVLFVKPIEKNAGGNLNVLTNKRSYVFFLKGEFRP
CCCCCEEEECCCCCCEEEECCCCCCCEEEEEECCCCCCCCEEEEECCCEEEEEEECCCCH
VAQQVYAIKFRYPEEASDAALMDEARARASQPNRQGFKAENANSSYAYKGSSANKPLVIY
HHEEEEEEEEECCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCEEECCCCCCCCEEEE
DDGVKTWFRFDPAREVPAIYVVDSERNETLVNYRREGAYIVVDKVNFQWTLRNGHDATCV
ECCCCEEEEECCCCCCCEEEEEECCCCCEEEEEECCCCEEEEEECEEEEEEECCCCEEEE
FNLRLNNVNEPTGLEPYQPQRVGGGVVQKVRGPDAISQ
EEEEECCCCCCCCCCCCCCCCCCCHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA