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The map label for this gene is dppA [H]

Identifier: 13488240

GI number: 13488240

Start: 189610

End: 191193

Strand: Direct

Name: dppA [H]

Synonym: mlr9210

Alternate gene names: 13488240

Gene position: 189610-191193 (Clockwise)

Preceding gene: 13488239

Following gene: 13488241

Centisome position: 53.88

GC content: 58.4

Gene sequence:

>1584_bases
ATGACAAATGAAATCCATCGTCTAGGCCAACAGGTTGTATCGGGAATACTATCTCGTCGTGATTTTCTTGGGCGTGCCGC
TGCGCTCGGTCTTAGCGCACCTTTCGCCAACTCGCTGCTTTCCAATGCAGCGCGCGCCGCGCAACCGGTCAAGGGCGGAA
CACTTAAGGCTGGCCTGCAGGGCGGAGCGGCCACCGACACTCTGGACACGGCACACTTTTCGACCTCGGTAGATATTACC
TTCGGTCGCGCATGGGGTGAACAGCTTGTGCAGATCGATCCCAAGGGCGGACTTCAGCCGGCACTCGCCGAAGAGTGGGG
CTCGTCGAAGGACGCCAAGGTCTGGACCTTCAAAATCCGCAAGGGCGTGCATTTCCACGATGGCAAGGAAATGACCCCGG
CCGACGTGCTTGCCACTATGGAGCGCCATTCCGACAAGAATTCAAAGTCGGGCGCGCTCGGCATCATGCAGGGCATCGAT
AAGATTGCTGTCGACGGCCAAAATGTGGTCTTTACGCTCAAGGACCCCAACGCCGACCTCCCCTTCCTAATGGATGACTA
CCACTTGATCATTCAGCCGAATGGCGGCAAGGACAACCCGGCCGCAGGGATTGGCACCGGCCCCTACAAGGTGACGACCA
ACGAACCCGGCGTCCGTCTCGGGGGTGAAAAGTTCGCCGGATATTGGCGCGACGACCGCGGCTTTGCCGACCAGGTCGAA
GTCATTGTCATCAATGATGCGACGGCCCGAATGTCCGCTTTGCAGAGCGGCCAGGTGCACATCGTCAACTTTGTCCAGCC
GAAACTCGTCGATCTCATCAAGCGGGTACCGGGCATGACCATCCGGAACGTGTCAGGCCGTGGCCACTACGTCTTTGTCG
CCCGCTGTAAGACGGCGCCATTCGACAACAACGACCTGCGCTTGGCTTTGAAGTTTGCGATCGACCGCGACGAGATGCTG
GACAAAGTGCTGCGCGGCTATGGCACGGTCGGCAACGACTTCCCGATCAACGCCGCCTACCCGCTGTTCACCGAGGTTGA
GCAGCGCAAATACGATCCCGACAAGGCCAAGTTCCACTACAAGAAGTCCGGCCATGACGGCCCCGTGCTGCTGAGGACGT
CGGACGTCGCCTTCCCCGGTGCCGTCGATGCCGCACAGCTGTTCCAGCAAAGTGCTGCCAAGGCCGGCATCCAGCTCGAG
ATTAAGCGCGAACCGGGCGACGGATACTGGTCAGAAGTCTGGCAAAAGCAGCCCTTCTGCGCCTCCTACTGGGGCGGCCG
CCCGACCCAGGATCAAATGTATTCCGTGGGCTACTACTCCAAAGCTGACTGGAACGAATCGCAATTCGTCAACGACAAGT
TTGACAAAATGCTTTTCCAGGCTCGCGCCGAGTTGGATCCCGAGAAGCGCAAGAAGATTTACGCAGACATGGGCACAATT
GTGAATCAGGAAGGCGGTACCATCGTCCCGATGTTCAACCAGTTCATTGATGCGACCGGCGCAAAGGTTGAGGGTTGGAT
CGACGATCCGAACTATGAGCTGTCAGGATACTATGCCCTGTCACGGTGCTGGATTGCCGGTTGA

Upstream 100 bases:

>100_bases
CAGCACCAGAAGCATCATACCAGTATATAGATCGTCATGCAGGTTGATGAAAAGCACACTCAGATAACTAGCCGCAATGG
CGTAAAAAAGGGGAAGTACC

Downstream 100 bases:

>100_bases
ATCGGAACCAGTAGATGTCTTCTTCTATCGCGAAACTTGGTGCCCAGCGGATTGCGCTGGGCATCATGCTGCTATTGGCC
GTCTCGGTCCTGATCTTCGC

Product: dipeptide binding protein

Products: ADP; phosphate; dipeptides [Cytoplasm] [C]

Alternate protein names: Dipeptide-binding protein; DBP [H]

Number of amino acids: Translated: 527; Mature: 526

Protein sequence:

>527_residues
MTNEIHRLGQQVVSGILSRRDFLGRAAALGLSAPFANSLLSNAARAAQPVKGGTLKAGLQGGAATDTLDTAHFSTSVDIT
FGRAWGEQLVQIDPKGGLQPALAEEWGSSKDAKVWTFKIRKGVHFHDGKEMTPADVLATMERHSDKNSKSGALGIMQGID
KIAVDGQNVVFTLKDPNADLPFLMDDYHLIIQPNGGKDNPAAGIGTGPYKVTTNEPGVRLGGEKFAGYWRDDRGFADQVE
VIVINDATARMSALQSGQVHIVNFVQPKLVDLIKRVPGMTIRNVSGRGHYVFVARCKTAPFDNNDLRLALKFAIDRDEML
DKVLRGYGTVGNDFPINAAYPLFTEVEQRKYDPDKAKFHYKKSGHDGPVLLRTSDVAFPGAVDAAQLFQQSAAKAGIQLE
IKREPGDGYWSEVWQKQPFCASYWGGRPTQDQMYSVGYYSKADWNESQFVNDKFDKMLFQARAELDPEKRKKIYADMGTI
VNQEGGTIVPMFNQFIDATGAKVEGWIDDPNYELSGYYALSRCWIAG

Sequences:

>Translated_527_residues
MTNEIHRLGQQVVSGILSRRDFLGRAAALGLSAPFANSLLSNAARAAQPVKGGTLKAGLQGGAATDTLDTAHFSTSVDIT
FGRAWGEQLVQIDPKGGLQPALAEEWGSSKDAKVWTFKIRKGVHFHDGKEMTPADVLATMERHSDKNSKSGALGIMQGID
KIAVDGQNVVFTLKDPNADLPFLMDDYHLIIQPNGGKDNPAAGIGTGPYKVTTNEPGVRLGGEKFAGYWRDDRGFADQVE
VIVINDATARMSALQSGQVHIVNFVQPKLVDLIKRVPGMTIRNVSGRGHYVFVARCKTAPFDNNDLRLALKFAIDRDEML
DKVLRGYGTVGNDFPINAAYPLFTEVEQRKYDPDKAKFHYKKSGHDGPVLLRTSDVAFPGAVDAAQLFQQSAAKAGIQLE
IKREPGDGYWSEVWQKQPFCASYWGGRPTQDQMYSVGYYSKADWNESQFVNDKFDKMLFQARAELDPEKRKKIYADMGTI
VNQEGGTIVPMFNQFIDATGAKVEGWIDDPNYELSGYYALSRCWIAG
>Mature_526_residues
TNEIHRLGQQVVSGILSRRDFLGRAAALGLSAPFANSLLSNAARAAQPVKGGTLKAGLQGGAATDTLDTAHFSTSVDITF
GRAWGEQLVQIDPKGGLQPALAEEWGSSKDAKVWTFKIRKGVHFHDGKEMTPADVLATMERHSDKNSKSGALGIMQGIDK
IAVDGQNVVFTLKDPNADLPFLMDDYHLIIQPNGGKDNPAAGIGTGPYKVTTNEPGVRLGGEKFAGYWRDDRGFADQVEV
IVINDATARMSALQSGQVHIVNFVQPKLVDLIKRVPGMTIRNVSGRGHYVFVARCKTAPFDNNDLRLALKFAIDRDEMLD
KVLRGYGTVGNDFPINAAYPLFTEVEQRKYDPDKAKFHYKKSGHDGPVLLRTSDVAFPGAVDAAQLFQQSAAKAGIQLEI
KREPGDGYWSEVWQKQPFCASYWGGRPTQDQMYSVGYYSKADWNESQFVNDKFDKMLFQARAELDPEKRKKIYADMGTIV
NQEGGTIVPMFNQFIDATGAKVEGWIDDPNYELSGYYALSRCWIAG

Specific function: Dipeptide-binding protein of a transport system that can be subject to osmotic shock. DppA is also required for peptide chemotaxis [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial solute-binding protein 5 family [H]

Homologues:

Organism=Escherichia coli, GI1789966, Length=458, Percent_Identity=24.0174672489083, Blast_Score=120, Evalue=1e-28,
Organism=Escherichia coli, GI1787052, Length=511, Percent_Identity=25.6360078277886, Blast_Score=117, Evalue=2e-27,
Organism=Escherichia coli, GI1787495, Length=520, Percent_Identity=23.2692307692308, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI1787762, Length=518, Percent_Identity=24.5173745173745, Blast_Score=72, Evalue=8e-14,
Organism=Escherichia coli, GI1787551, Length=480, Percent_Identity=21.0416666666667, Blast_Score=71, Evalue=2e-13,

Paralogues:

None

Copy number: 660 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2980 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 40 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000914 [H]

Pfam domain/function: PF00496 SBP_bac_5 [H]

EC number: NA

Molecular weight: Translated: 57986; Mature: 57855

Theoretical pI: Translated: 7.07; Mature: 7.07

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTNEIHRLGQQVVSGILSRRDFLGRAAALGLSAPFANSLLSNAARAAQPVKGGTLKAGLQ
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCCEEECCC
GGAATDTLDTAHFSTSVDITFGRAWGEQLVQIDPKGGLQPALAEEWGSSKDAKVWTFKIR
CCCCCCCCCCCCCCEEEEEEECCCCCCCEEEECCCCCCCCHHHHHCCCCCCCEEEEEEEE
KGVHFHDGKEMTPADVLATMERHSDKNSKSGALGIMQGIDKIAVDGQNVVFTLKDPNADL
CCCEECCCCCCCHHHHHHHHHHHCCCCCCCCCHHHHHCCHHEEECCCEEEEEECCCCCCC
PFLMDDYHLIIQPNGGKDNPAAGIGTGPYKVTTNEPGVRLGGEKFAGYWRDDRGFADQVE
CEEECCEEEEEECCCCCCCCCCCCCCCCEEEECCCCCCEECCHHHCCCCCCCCCCCCCEE
VIVINDATARMSALQSGQVHIVNFVQPKLVDLIKRVPGMTIRNVSGRGHYVFVARCKTAP
EEEEECCHHHHHHHCCCCEEEEECCCHHHHHHHHHCCCCEEEECCCCCCEEEEEEEECCC
FDNNDLRLALKFAIDRDEMLDKVLRGYGTVGNDFPINAAYPLFTEVEQRKYDPDKAKFHY
CCCCCEEEEEEEECCHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHCCCCCHHEEEE
KKSGHDGPVLLRTSDVAFPGAVDAAQLFQQSAAKAGIQLEIKREPGDGYWSEVWQKQPFC
ECCCCCCCEEEEECCCCCCCCCHHHHHHHHHHHCCCEEEEEEECCCCCHHHHHHCCCCCC
ASYWGGRPTQDQMYSVGYYSKADWNESQFVNDKFDKMLFQARAELDPEKRKKIYADMGTI
HHHCCCCCCHHHEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHH
VNQEGGTIVPMFNQFIDATGAKVEGWIDDPNYELSGYYALSRCWIAG
EECCCCEEHHHHHHHHHCCCCEEEEEECCCCCEEEEEEEEEEEEECC
>Mature Secondary Structure 
TNEIHRLGQQVVSGILSRRDFLGRAAALGLSAPFANSLLSNAARAAQPVKGGTLKAGLQ
CHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCCEEECCC
GGAATDTLDTAHFSTSVDITFGRAWGEQLVQIDPKGGLQPALAEEWGSSKDAKVWTFKIR
CCCCCCCCCCCCCCEEEEEEECCCCCCCEEEECCCCCCCCHHHHHCCCCCCCEEEEEEEE
KGVHFHDGKEMTPADVLATMERHSDKNSKSGALGIMQGIDKIAVDGQNVVFTLKDPNADL
CCCEECCCCCCCHHHHHHHHHHHCCCCCCCCCHHHHHCCHHEEECCCEEEEEECCCCCCC
PFLMDDYHLIIQPNGGKDNPAAGIGTGPYKVTTNEPGVRLGGEKFAGYWRDDRGFADQVE
CEEECCEEEEEECCCCCCCCCCCCCCCCEEEECCCCCCEECCHHHCCCCCCCCCCCCCEE
VIVINDATARMSALQSGQVHIVNFVQPKLVDLIKRVPGMTIRNVSGRGHYVFVARCKTAP
EEEEECCHHHHHHHCCCCEEEEECCCHHHHHHHHHCCCCEEEECCCCCCEEEEEEEECCC
FDNNDLRLALKFAIDRDEMLDKVLRGYGTVGNDFPINAAYPLFTEVEQRKYDPDKAKFHY
CCCCCEEEEEEEECCHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHCCCCCHHEEEE
KKSGHDGPVLLRTSDVAFPGAVDAAQLFQQSAAKAGIQLEIKREPGDGYWSEVWQKQPFC
ECCCCCCCEEEEECCCCCCCCCHHHHHHHHHHHCCCEEEEEEECCCCCHHHHHHCCCCCC
ASYWGGRPTQDQMYSVGYYSKADWNESQFVNDKFDKMLFQARAELDPEKRKKIYADMGTI
HHHCCCCCCHHHEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHH
VNQEGGTIVPMFNQFIDATGAKVEGWIDDPNYELSGYYALSRCWIAG
EECCCCEEHHHHHHHHHCCCCEEEEEECCCCCEEEEEEEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; dipeptides [Periplasm]; H2O [C]

Specific reaction: ATP + dipeptides [Periplasm] + H2O = ADP + phosphate + dipeptides [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1702779; 1956284; 7536291; 8041620; 9278503; 9298646; 9600841; 8563629; 8527431 [H]