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The map label for this gene is lrp [C]

Identifier: 13488125

GI number: 13488125

Start: 206862

End: 207338

Strand: Reverse

Name: lrp [C]

Synonym: mll9224

Alternate gene names: 13488125

Gene position: 207338-206862 (Counterclockwise)

Preceding gene: 161621457

Following gene: 13488124

Centisome position: 58.92

GC content: 53.04

Gene sequence:

>477_bases
ATGACGCAGGCTGGCAAAACTCGGCTCGACGATTTCGACATAAAAATCCTGCAATTGGTGCAGTTCGACAGCCTCATGCC
GCAGCACGAAATTTCGGACCGCGTTGGCCTCTCTGCAGCGGCGGTGGCGAGACGCCTAAAACGGCTTTCGTCCACAGGGA
TAATCAGAAAGGACATGTCCATCTCAAACGAGAGAGCGGTTGGGAGTCCTCAGACGGTCATCGTCGAGGTGACGGCTAAA
AACGGAAAACCGCATTTGCTCGACGGGATGAAAAGACGGTTCCTGAACTGCCCTCAGGTGCAGCAATGCTACCACGTTAC
CGGAGGGGCAGACTTCATCCTCATCATTAACACCAGGGGGATGGACGAGTATACGTTTCTCACACGCCAATTATTTTTCC
AGGAAGGAAACGTGAAGAGCTTCCGAACTCGCGTCATGATGGAAGAGGTTAAGTCCGCGGATCCAATCCCGCTTTAG

Upstream 100 bases:

>100_bases
ATGTCGTTCGAGCCCTCCTTACCGTCCAGACGCTGCGACGTGAGAACTATCATGGCCCAGAATTTGCGCTGAGAGCCACC
TATATCAGGAGAACGCCTAG

Downstream 100 bases:

>100_bases
CCATCGCAATTCCGGCGCTTCGACTTCAGCTTCGCCGCTTCACGCTCGAGGTACTGGATCAGTTTGAGAGTCTGAACGGG
TATAGCAAGAGCGATTTGAC

Product: transcription regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 158; Mature: 157

Protein sequence:

>158_residues
MTQAGKTRLDDFDIKILQLVQFDSLMPQHEISDRVGLSAAAVARRLKRLSSTGIIRKDMSISNERAVGSPQTVIVEVTAK
NGKPHLLDGMKRRFLNCPQVQQCYHVTGGADFILIINTRGMDEYTFLTRQLFFQEGNVKSFRTRVMMEEVKSADPIPL

Sequences:

>Translated_158_residues
MTQAGKTRLDDFDIKILQLVQFDSLMPQHEISDRVGLSAAAVARRLKRLSSTGIIRKDMSISNERAVGSPQTVIVEVTAK
NGKPHLLDGMKRRFLNCPQVQQCYHVTGGADFILIINTRGMDEYTFLTRQLFFQEGNVKSFRTRVMMEEVKSADPIPL
>Mature_157_residues
TQAGKTRLDDFDIKILQLVQFDSLMPQHEISDRVGLSAAAVARRLKRLSSTGIIRKDMSISNERAVGSPQTVIVEVTAKN
GKPHLLDGMKRRFLNCPQVQQCYHVTGGADFILIINTRGMDEYTFLTRQLFFQEGNVKSFRTRVMMEEVKSADPIPL

Specific function: Mediates A Global Response To Leucine. Exogenous Leucine Affects The Expression Of A Number Of Different Operons; Lrp Mediates This Effect For At Least Some Of These Operons. For Example It Is Regulator Of The Branched-Chain Amino Acid Transport Genes. [

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH asnC-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1787116, Length=146, Percent_Identity=30.1369863013699, Blast_Score=72, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011008
- InterPro:   IPR013196
- InterPro:   IPR000485
- InterPro:   IPR019885
- InterPro:   IPR019888
- InterPro:   IPR019887
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01037 AsnC_trans_reg; PF08279 HTH_11 [H]

EC number: NA

Molecular weight: Translated: 17842; Mature: 17711

Theoretical pI: Translated: 9.98; Mature: 9.98

Prosite motif: PS00519 HTH_ASNC_1 ; PS50956 HTH_ASNC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
4.4 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTQAGKTRLDDFDIKILQLVQFDSLMPQHEISDRVGLSAAAVARRLKRLSSTGIIRKDMS
CCCCCCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHCCHHHHHHHHHHHHHHCCCEECCCC
ISNERAVGSPQTVIVEVTAKNGKPHLLDGMKRRFLNCPQVQQCYHVTGGADFILIINTRG
CCCCCCCCCCCEEEEEEECCCCCCHHHHHHHHHHCCCCCHHHHEEECCCCCEEEEEECCC
MDEYTFLTRQLFFQEGNVKSFRTRVMMEEVKSADPIPL
CCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
TQAGKTRLDDFDIKILQLVQFDSLMPQHEISDRVGLSAAAVARRLKRLSSTGIIRKDMS
CCCCCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHCCHHHHHHHHHHHHHHCCCEECCCC
ISNERAVGSPQTVIVEVTAKNGKPHLLDGMKRRFLNCPQVQQCYHVTGGADFILIINTRG
CCCCCCCCCCCEEEEEEECCCCCCHHHHHHHHHHCCCCCHHHHEEECCCCCEEEEEECCC
MDEYTFLTRQLFFQEGNVKSFRTRVMMEEVKSADPIPL
CCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9163424 [H]