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The map label for this gene is 15603871

Identifier: 15603871

GI number: 15603871

Start: 2246309

End: 2248675

Strand: Direct

Name: 15603871

Synonym: PM2006

Alternate gene names: NA

Gene position: 2246309-2248675 (Clockwise)

Preceding gene: 15603870

Following gene: 15603872

Centisome position: 99.5

GC content: 34.14

Gene sequence:

>2367_bases
ATGACTAAATCTGAACAGTATTTTGATCAAGCTAAACAAGCATATGATGATGGAAATTTTGAAAAAGCGATTGAGTTATT
CAATAAAATTAATCCGCATGATAAGGCTCTCTATTTCCTAGCACAATTTAATTTAGCATCTATTTTGAGAGAAAAAGGAG
AGCTGGATAAGGCGATAGAGACTTATCGAACCATTTCACGTGGAGATATTCCTAAGGTTTATGCTCAAGCACAATTTAAT
TTAGCAGGTATTTTGGTAGAAAAAGGTGCGCTAGATAAGGCGATAGCGACTTATTGTGCTATTTCACGTGAAGATGACCC
TGAAGCGTATGCCAAAGCACAATTGCAGCTAGCGCTTATTTGGGCAGAAAAAGGTGAACCGGATAAAGCGATAAAGGCTT
GTAATTCGGTTTTACGTGAAGATAACCCTGAGGCTTATGCGAAAGCACAATTCCAATTAGCGTTTATTTTTGTAGAAAAA
AATGAACGGGATAAAGCGATCGAAGCTTATGAAGCTATTTTACGTGAAGATAGTCCTGAGGCTTATGCGCAAGCACAATT
TCAGCTAGCGCTTATTTGGGCAGAAAAAGGTGAACCGGATAAAGCGATAAAGGCTTGTAATTCGGTTTTACGTGAAGATA
ACCCTGAGGCTTATGCGAAAGCACAATTCCAATTAGCGTTTATTTTTGTAGAAAAAAATGAACGGGATAAAGCGATCGAA
GCTTATGAAGCTATTTTACGTGAAGATAGTCCTGAGGCTTATGCGAAAGCACAATTTCAGCTAGCGCTTATTTGGGCAGA
AAAAGGTGACAAGAATAAAGCGATAAAGGCTTATAGATCAGTTTTACGTGAAGATAACCCTGATGCTTATGCGAAAGCAC
AATTTAATTTAGCATTTCTGTTGTCAAAAAAAAGTGAACTGGATAAAGCGATAAAGGCTTGTAATTCGGTTTTGCGTGAA
GATAGTCCTGAGGCTTATGCGAAAGCACAATTTCAGCTAGCGCTTATTTGGGCAGAAAAAGGTGACAAGAATAAAGCGAT
AAAGGCTTATAGGTCAGTTTTACGCGAAGATAACCCTGAGGCTTATGCAAAAGCACAATTTCAGTTAGCGTGTATTTTTA
TAGAAAAAGATGAACCGGATAAAGCGATAAAGGCTTGTAATTCAGTTTTGCATGAAGATAACCCTGATGTTTATGCGAAA
GCACAATTTATTCTAGGTATCTTATATAAATCTCAAAGTGATTTTAAAAAAGCAATAGAGGCTTATTCAAATGCTTATGG
TAGCAATGATCCAGCTATATATTATTGTGCAAAAGCAGAAATTCTACTTTTATCTGTTAAAGGATCTGAAAGAGAAGATC
TGTATGTTATATATTCAAATGTTATTCAAATATTGAATATATTGCACGTTATTTTTGATGGCGATACTGAAGAGGATTGT
AAGCAAGTTGCACACTATACGCGTCCTTCAACAGCCTTGAAATTATTAGGTTTAGATAATACAAACGGAAATTCTAGCTT
TAGATTAAGTACAATTCATGGCGTTAATGATCCGACAGAGGGGCGCGTTTTTTATGATTTTCTTAATTTCAGAGAAATGC
TAGAGCAAAAAGATAATACAGCTTTTATTAGTTGCTTTACATTTAATCATGATAGCTTAAATCAGTTTCGTCTATATGGT
AAAGAGGAGGGAAAAGAGGCGTCTGGTGTGAGTATGGTATTTAATGTTAAAAATTTTTTTAACAATAACTCAAATCAAAT
GTTTATTCCCTTTTCAAAGGATTTAATAAAAGTTAGTAAGAGTGAAAACACACAAGAAAGTCAAATTAATAAAAGTCATC
AAGAGACTTATTTACCTTTATATCGCTGTGTCTATCTTGATCCTGTTACTGGATATATATCTCTAGCCAAAAGAACAAGA
ATAACTTTTTTCAGAGAAAATGAGGAAAACTCAGATAACAGATGGCGTGAGTATCAGAACAAAATGTTGGAAAAAGAAAC
ACAAGTCCAAAAACATTTAAATAAAATAAAAGAAACTTTAGCGAAGATTAAAGGAAAAGATAAAGTTAATGAAGTTGTAC
AAGATATACTTTTACCTCTCAAATATTTAGTTAAACATTATGCTTTTGAAGAAGAACAAGAATGTCGAATGATCGCTATC
CATTCATTAATTAAAGAAAGTGATAAGGTTAAAATAGACATCACTAAAAAATCCATGTATGTGGAATACTTCATTGATGT
AAAAACTGCCATCGAAAAAGTGTATTTATCTGTGGGGGCTAAAGAATATGAAAGCTTCTTTATTAAAGCATTAGGCGATA
GTAGAAAAGTCCGTATTTCTGATAATCCTTTCCGAGCTAAGTCGTAA

Upstream 100 bases:

>100_bases
ACACCGCACTTTTTCTTGTCAAGAAAGTGCGGTGTTTGTTTAAAGCTGATGAGCCGTTGTGAAAATATCATTTTAAGTCT
AAATAATTGAGGGAATAATT

Downstream 100 bases:

>100_bases
GATAAAACTTTTCTAAAACATACCGCACTTTTTCTTTCACGATCGAGATCGCAAAAAAGTGCGGTGTTTTTTTACAGAGT
TTGGCGAAATTGCTAGATTA

Product: hypothetical protein

Products: NA

Alternate protein names: Peptidase; TPR Domain-Containing Protein; TPR Repeat Protein; Tetratricopeptide TPR_2 Repeat Protein; Tetratricopeptide Repeat Family; Tetratricopeptide TPR_1 Repeat-Containing Protein; Peptidase S1 And S6 Chymotrypsin/Hap; Tetratricopeptide Repeat Domain Protein

Number of amino acids: Translated: 788; Mature: 787

Protein sequence:

>788_residues
MTKSEQYFDQAKQAYDDGNFEKAIELFNKINPHDKALYFLAQFNLASILREKGELDKAIETYRTISRGDIPKVYAQAQFN
LAGILVEKGALDKAIATYCAISREDDPEAYAKAQLQLALIWAEKGEPDKAIKACNSVLREDNPEAYAKAQFQLAFIFVEK
NERDKAIEAYEAILREDSPEAYAQAQFQLALIWAEKGEPDKAIKACNSVLREDNPEAYAKAQFQLAFIFVEKNERDKAIE
AYEAILREDSPEAYAKAQFQLALIWAEKGDKNKAIKAYRSVLREDNPDAYAKAQFNLAFLLSKKSELDKAIKACNSVLRE
DSPEAYAKAQFQLALIWAEKGDKNKAIKAYRSVLREDNPEAYAKAQFQLACIFIEKDEPDKAIKACNSVLHEDNPDVYAK
AQFILGILYKSQSDFKKAIEAYSNAYGSNDPAIYYCAKAEILLLSVKGSEREDLYVIYSNVIQILNILHVIFDGDTEEDC
KQVAHYTRPSTALKLLGLDNTNGNSSFRLSTIHGVNDPTEGRVFYDFLNFREMLEQKDNTAFISCFTFNHDSLNQFRLYG
KEEGKEASGVSMVFNVKNFFNNNSNQMFIPFSKDLIKVSKSENTQESQINKSHQETYLPLYRCVYLDPVTGYISLAKRTR
ITFFRENEENSDNRWREYQNKMLEKETQVQKHLNKIKETLAKIKGKDKVNEVVQDILLPLKYLVKHYAFEEEQECRMIAI
HSLIKESDKVKIDITKKSMYVEYFIDVKTAIEKVYLSVGAKEYESFFIKALGDSRKVRISDNPFRAKS

Sequences:

>Translated_788_residues
MTKSEQYFDQAKQAYDDGNFEKAIELFNKINPHDKALYFLAQFNLASILREKGELDKAIETYRTISRGDIPKVYAQAQFN
LAGILVEKGALDKAIATYCAISREDDPEAYAKAQLQLALIWAEKGEPDKAIKACNSVLREDNPEAYAKAQFQLAFIFVEK
NERDKAIEAYEAILREDSPEAYAQAQFQLALIWAEKGEPDKAIKACNSVLREDNPEAYAKAQFQLAFIFVEKNERDKAIE
AYEAILREDSPEAYAKAQFQLALIWAEKGDKNKAIKAYRSVLREDNPDAYAKAQFNLAFLLSKKSELDKAIKACNSVLRE
DSPEAYAKAQFQLALIWAEKGDKNKAIKAYRSVLREDNPEAYAKAQFQLACIFIEKDEPDKAIKACNSVLHEDNPDVYAK
AQFILGILYKSQSDFKKAIEAYSNAYGSNDPAIYYCAKAEILLLSVKGSEREDLYVIYSNVIQILNILHVIFDGDTEEDC
KQVAHYTRPSTALKLLGLDNTNGNSSFRLSTIHGVNDPTEGRVFYDFLNFREMLEQKDNTAFISCFTFNHDSLNQFRLYG
KEEGKEASGVSMVFNVKNFFNNNSNQMFIPFSKDLIKVSKSENTQESQINKSHQETYLPLYRCVYLDPVTGYISLAKRTR
ITFFRENEENSDNRWREYQNKMLEKETQVQKHLNKIKETLAKIKGKDKVNEVVQDILLPLKYLVKHYAFEEEQECRMIAI
HSLIKESDKVKIDITKKSMYVEYFIDVKTAIEKVYLSVGAKEYESFFIKALGDSRKVRISDNPFRAKS
>Mature_787_residues
TKSEQYFDQAKQAYDDGNFEKAIELFNKINPHDKALYFLAQFNLASILREKGELDKAIETYRTISRGDIPKVYAQAQFNL
AGILVEKGALDKAIATYCAISREDDPEAYAKAQLQLALIWAEKGEPDKAIKACNSVLREDNPEAYAKAQFQLAFIFVEKN
ERDKAIEAYEAILREDSPEAYAQAQFQLALIWAEKGEPDKAIKACNSVLREDNPEAYAKAQFQLAFIFVEKNERDKAIEA
YEAILREDSPEAYAKAQFQLALIWAEKGDKNKAIKAYRSVLREDNPDAYAKAQFNLAFLLSKKSELDKAIKACNSVLRED
SPEAYAKAQFQLALIWAEKGDKNKAIKAYRSVLREDNPEAYAKAQFQLACIFIEKDEPDKAIKACNSVLHEDNPDVYAKA
QFILGILYKSQSDFKKAIEAYSNAYGSNDPAIYYCAKAEILLLSVKGSEREDLYVIYSNVIQILNILHVIFDGDTEEDCK
QVAHYTRPSTALKLLGLDNTNGNSSFRLSTIHGVNDPTEGRVFYDFLNFREMLEQKDNTAFISCFTFNHDSLNQFRLYGK
EEGKEASGVSMVFNVKNFFNNNSNQMFIPFSKDLIKVSKSENTQESQINKSHQETYLPLYRCVYLDPVTGYISLAKRTRI
TFFRENEENSDNRWREYQNKMLEKETQVQKHLNKIKETLAKIKGKDKVNEVVQDILLPLKYLVKHYAFEEEQECRMIAIH
SLIKESDKVKIDITKKSMYVEYFIDVKTAIEKVYLSVGAKEYESFFIKALGDSRKVRISDNPFRAKS

Specific function: Unknown

COG id: COG0457

COG function: function code R; FOG: TPR repeat

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI32307150, Length=449, Percent_Identity=26.0579064587973, Blast_Score=67, Evalue=5e-11,
Organism=Homo sapiens, GI32307148, Length=449, Percent_Identity=26.0579064587973, Blast_Score=67, Evalue=6e-11,
Organism=Caenorhabditis elegans, GI115532692, Length=385, Percent_Identity=28.3116883116883, Blast_Score=71, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI115532690, Length=385, Percent_Identity=28.3116883116883, Blast_Score=70, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 90283; Mature: 90152

Theoretical pI: Translated: 5.98; Mature: 5.98

Prosite motif: PS50005 TPR L=RR ; PS50293 TPR_REGION

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKSEQYFDQAKQAYDDGNFEKAIELFNKINPHDKALYFLAQFNLASILREKGELDKAIE
CCCCHHHHHHHHHHCCCCCHHHHHHHHHCCCCCHHHEEHHHHHHHHHHHHHHCHHHHHHH
TYRTISRGDIPKVYAQAQFNLAGILVEKGALDKAIATYCAISREDDPEAYAKAQLQLALI
HHHHHCCCCCCHHHHHHCCCEEEEEEECCCHHHHHHHHHHCCCCCCHHHHHHHEEEEEEE
WAEKGEPDKAIKACNSVLREDNPEAYAKAQFQLAFIFVEKNERDKAIEAYEAILREDSPE
EECCCCCHHHHHHHHHHHHCCCCCHHHEEEEEEEEEEEECCCCHHHHHHHHHHHCCCCCH
AYAQAQFQLALIWAEKGEPDKAIKACNSVLREDNPEAYAKAQFQLAFIFVEKNERDKAIE
HHHHHEEEEEEEEECCCCCHHHHHHHHHHHHCCCCCHHHEEEEEEEEEEEECCCCHHHHH
AYEAILREDSPEAYAKAQFQLALIWAEKGDKNKAIKAYRSVLREDNPDAYAKAQFNLAFL
HHHHHHCCCCCCHHHHEEEEEEEEEECCCCCHHHHHHHHHHHCCCCCCCEEEEEEEEEEE
LSKKSELDKAIKACNSVLREDSPEAYAKAQFQLALIWAEKGDKNKAIKAYRSVLREDNPE
ECCHHHHHHHHHHHHHHHHCCCCCHHHHEEEEEEEEEECCCCCHHHHHHHHHHHCCCCCC
AYAKAQFQLACIFIEKDEPDKAIKACNSVLHEDNPDVYAKAQFILGILYKSQSDFKKAIE
HHHEEEEEEEEEEEECCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCHHHHHHHHH
AYSNAYGSNDPAIYYCAKAEILLLSVKGSEREDLYVIYSNVIQILNILHVIFDGDTEEDC
HHHHCCCCCCCEEEEEECCEEEEEEECCCCCCCEEEEHHHHHHHHHHHHHHCCCCCHHHH
KQVAHYTRPSTALKLLGLDNTNGNSSFRLSTIHGVNDPTEGRVFYDFLNFREMLEQKDNT
HHHHHCCCCCCEEEEEECCCCCCCCEEEEEEEECCCCCCCCEEHHHHHHHHHHHHCCCCC
AFISCFTFNHDSLNQFRLYGKEEGKEASGVSMVFNVKNFFNNNSNQMFIPFSKDLIKVSK
EEEEEEEECCCCCCHHEECCCCCCCCCCCCEEEEEEHHHHCCCCCEEEEECCHHHHHHCC
SENTQESQINKSHQETYLPLYRCVYLDPVTGYISLAKRTRITFFRENEENSDNRWREYQN
CCCCHHHHHHHHHHHHHHHHHHEEEECCCHHHHHHHHHHEEEEEECCCCCCHHHHHHHHH
KMLEKETQVQKHLNKIKETLAKIKGKDKVNEVVQDILLPLKYLVKHYAFEEEQECRMIAI
HHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHH
HSLIKESDKVKIDITKKSMYVEYFIDVKTAIEKVYLSVGAKEYESFFIKALGDSRKVRIS
HHHHCCCCCEEEEEEEEEEEEEHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCEEEEC
DNPFRAKS
CCCCCCCC
>Mature Secondary Structure 
TKSEQYFDQAKQAYDDGNFEKAIELFNKINPHDKALYFLAQFNLASILREKGELDKAIE
CCCHHHHHHHHHHCCCCCHHHHHHHHHCCCCCHHHEEHHHHHHHHHHHHHHCHHHHHHH
TYRTISRGDIPKVYAQAQFNLAGILVEKGALDKAIATYCAISREDDPEAYAKAQLQLALI
HHHHHCCCCCCHHHHHHCCCEEEEEEECCCHHHHHHHHHHCCCCCCHHHHHHHEEEEEEE
WAEKGEPDKAIKACNSVLREDNPEAYAKAQFQLAFIFVEKNERDKAIEAYEAILREDSPE
EECCCCCHHHHHHHHHHHHCCCCCHHHEEEEEEEEEEEECCCCHHHHHHHHHHHCCCCCH
AYAQAQFQLALIWAEKGEPDKAIKACNSVLREDNPEAYAKAQFQLAFIFVEKNERDKAIE
HHHHHEEEEEEEEECCCCCHHHHHHHHHHHHCCCCCHHHEEEEEEEEEEEECCCCHHHHH
AYEAILREDSPEAYAKAQFQLALIWAEKGDKNKAIKAYRSVLREDNPDAYAKAQFNLAFL
HHHHHHCCCCCCHHHHEEEEEEEEEECCCCCHHHHHHHHHHHCCCCCCCEEEEEEEEEEE
LSKKSELDKAIKACNSVLREDSPEAYAKAQFQLALIWAEKGDKNKAIKAYRSVLREDNPE
ECCHHHHHHHHHHHHHHHHCCCCCHHHHEEEEEEEEEECCCCCHHHHHHHHHHHCCCCCC
AYAKAQFQLACIFIEKDEPDKAIKACNSVLHEDNPDVYAKAQFILGILYKSQSDFKKAIE
HHHEEEEEEEEEEEECCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCHHHHHHHHH
AYSNAYGSNDPAIYYCAKAEILLLSVKGSEREDLYVIYSNVIQILNILHVIFDGDTEEDC
HHHHCCCCCCCEEEEEECCEEEEEEECCCCCCCEEEEHHHHHHHHHHHHHHCCCCCHHHH
KQVAHYTRPSTALKLLGLDNTNGNSSFRLSTIHGVNDPTEGRVFYDFLNFREMLEQKDNT
HHHHHCCCCCCEEEEEECCCCCCCCEEEEEEEECCCCCCCCEEHHHHHHHHHHHHCCCCC
AFISCFTFNHDSLNQFRLYGKEEGKEASGVSMVFNVKNFFNNNSNQMFIPFSKDLIKVSK
EEEEEEEECCCCCCHHEECCCCCCCCCCCCEEEEEEHHHHCCCCCEEEEECCHHHHHHCC
SENTQESQINKSHQETYLPLYRCVYLDPVTGYISLAKRTRITFFRENEENSDNRWREYQN
CCCCHHHHHHHHHHHHHHHHHHEEEECCCHHHHHHHHHHEEEEEECCCCCCHHHHHHHHH
KMLEKETQVQKHLNKIKETLAKIKGKDKVNEVVQDILLPLKYLVKHYAFEEEQECRMIAI
HHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHH
HSLIKESDKVKIDITKKSMYVEYFIDVKTAIEKVYLSVGAKEYESFFIKALGDSRKVRIS
HHHHCCCCCEEEEEEEEEEEEEHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCEEEEC
DNPFRAKS
CCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA