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The map label for this gene is mogA [H]

Identifier: 15603868

GI number: 15603868

Start: 2243976

End: 2244554

Strand: Direct

Name: mogA [H]

Synonym: PM2003

Alternate gene names: 15603868

Gene position: 2243976-2244554 (Clockwise)

Preceding gene: 15603867

Following gene: 15603869

Centisome position: 99.4

GC content: 45.08

Gene sequence:

>579_bases
ATGACCGCAGTTTTAAAAATTGGTTTAGTTTCAGTCTCTGATCGTGCTTCACAAGGCGTGTATGCTGATCAAGGGATTCC
TGAATTACAAGCTTGGTTAGAAAAGGCATTATGTGAGCCCTTTGAGATAGAAACTCGCTTAATTCCTGATGAGCAAGATC
GTATCGAACAAACCTTATGTGAACTCGTTGATGATTACCATTGCCACTTGGTGTTAACCACAGGCGGAACTGGACCGGCA
AAACGCGATGTCACACCTGATGCGACTCTCGCGGTGGCAGATCGTGAAATGCCGGGATTTGGTGAACAAATGCGCCAAGT
CAGTTTGCATTTCGTCCCAACGGCGATTTTATCGCGTCAAGTAGGCGTCATTCGCAAAAACAGTTTAATCCTCAATCTGC
CGGGGCAACCTAAAGCGATTAAAGAAACGCTAGAAGGGGTGAAAGATGAAAACGGTCAGGTTATTGTGAAAGGGATTTTT
AGTGCGGTGCCCTATTGTTTACAACTGATCAACGGGATTTATATTGATACTCATCCCGACGTGATTGAAAGTTTTCGCCC
TAAATCCGCCCGTCGTTAG

Upstream 100 bases:

>100_bases
ATGTTAGATCGCATGGACAGTTTATGCTTTGCAGCACCTATCTTCTTCCATGTGGTGAGATATTATTGGGTTTAGTTGGT
AATAAAAAATAGAGGAAAAA

Downstream 100 bases:

>100_bases
ACGAGTTAGCGGAGATAAAAGTGCGGTCAAAAAAGGAAAAATTTATGAAAAAGATTGAAGCAATCATTAAACCTTTCAAA
TTAGATGACGTACGTGAAAG

Product: molybdenum cofactor biosynthesis protein MogA

Products: NA

Alternate protein names: MPT adenylyltransferase [H]

Number of amino acids: Translated: 192; Mature: 191

Protein sequence:

>192_residues
MTAVLKIGLVSVSDRASQGVYADQGIPELQAWLEKALCEPFEIETRLIPDEQDRIEQTLCELVDDYHCHLVLTTGGTGPA
KRDVTPDATLAVADREMPGFGEQMRQVSLHFVPTAILSRQVGVIRKNSLILNLPGQPKAIKETLEGVKDENGQVIVKGIF
SAVPYCLQLINGIYIDTHPDVIESFRPKSARR

Sequences:

>Translated_192_residues
MTAVLKIGLVSVSDRASQGVYADQGIPELQAWLEKALCEPFEIETRLIPDEQDRIEQTLCELVDDYHCHLVLTTGGTGPA
KRDVTPDATLAVADREMPGFGEQMRQVSLHFVPTAILSRQVGVIRKNSLILNLPGQPKAIKETLEGVKDENGQVIVKGIF
SAVPYCLQLINGIYIDTHPDVIESFRPKSARR
>Mature_191_residues
TAVLKIGLVSVSDRASQGVYADQGIPELQAWLEKALCEPFEIETRLIPDEQDRIEQTLCELVDDYHCHLVLTTGGTGPAK
RDVTPDATLAVADREMPGFGEQMRQVSLHFVPTAILSRQVGVIRKNSLILNLPGQPKAIKETLEGVKDENGQVIVKGIFS
AVPYCLQLINGIYIDTHPDVIESFRPKSARR

Specific function: Catalyzes the adenylation of molybdopterin as part of the biosynthesis of the molybdenum-cofactor [H]

COG id: COG0521

COG function: function code H; Molybdopterin biosynthesis enzymes

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the moaB/mog family [H]

Homologues:

Organism=Homo sapiens, GI10880983, Length=167, Percent_Identity=34.1317365269461, Blast_Score=92, Evalue=3e-19,
Organism=Homo sapiens, GI66932975, Length=167, Percent_Identity=34.1317365269461, Blast_Score=92, Evalue=3e-19,
Organism=Escherichia coli, GI1786190, Length=188, Percent_Identity=78.1914893617021, Blast_Score=314, Evalue=2e-87,
Organism=Caenorhabditis elegans, GI17564954, Length=146, Percent_Identity=35.6164383561644, Blast_Score=83, Evalue=1e-16,
Organism=Drosophila melanogaster, GI17136978, Length=143, Percent_Identity=34.965034965035, Blast_Score=84, Evalue=8e-17,
Organism=Drosophila melanogaster, GI24638841, Length=143, Percent_Identity=34.965034965035, Blast_Score=84, Evalue=8e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020817
- InterPro:   IPR008284
- InterPro:   IPR001453 [H]

Pfam domain/function: PF00994 MoCF_biosynth [H]

EC number: NA

Molecular weight: Translated: 21191; Mature: 21059

Theoretical pI: Translated: 5.07; Mature: 5.07

Prosite motif: PS01078 MOCF_BIOSYNTHESIS_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTAVLKIGLVSVSDRASQGVYADQGIPELQAWLEKALCEPFEIETRLIPDEQDRIEQTLC
CCCEEEEEEEEECCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCEEECCCHHHHHHHHHH
ELVDDYHCHLVLTTGGTGPAKRDVTPDATLAVADREMPGFGEQMRQVSLHFVPTAILSRQ
HHHCCCCEEEEEEECCCCCCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHH
VGVIRKNSLILNLPGQPKAIKETLEGVKDENGQVIVKGIFSAVPYCLQLINGIYIDTHPD
HCEEEECCEEEECCCCCHHHHHHHHHHCCCCCCEEHHHHHHHHHHHHHHHCCEEECCCHH
VIESFRPKSARR
HHHHCCCCCCCC
>Mature Secondary Structure 
TAVLKIGLVSVSDRASQGVYADQGIPELQAWLEKALCEPFEIETRLIPDEQDRIEQTLC
CCEEEEEEEEECCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCEEECCCHHHHHHHHHH
ELVDDYHCHLVLTTGGTGPAKRDVTPDATLAVADREMPGFGEQMRQVSLHFVPTAILSRQ
HHHCCCCEEEEEEECCCCCCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHH
VGVIRKNSLILNLPGQPKAIKETLEGVKDENGQVIVKGIFSAVPYCLQLINGIYIDTHPD
HCEEEECCEEEECCCCCHHHHHHHHHHCCCCCCEEHHHHHHHHHHHHHHHCCEEECCCHH
VIESFRPKSARR
HHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800; 10675023 [H]